ID17266A - Antagonis antagonis reseptor d4 dopamin benzoksazinon - Google Patents

Antagonis antagonis reseptor d4 dopamin benzoksazinon

Info

Publication number: ID17266A
Authority: ID; Indonesia
Prior art keywords: antagonists; benzoksazinon; dopamin; receptor; receptor antagonists
Prior art date: 1996-05-29

Application number

IDP971778A

Other languages

English (en)

Inventor

Thomas Belliotti

Lawrence David Wise

David Juergen Wustrow

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-29

Filing date

1997-05-28

Publication date

1997-12-18

1997-05-28 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

1997-12-18 Publication of ID17266A publication Critical patent/ID17266A/id

Links

239000005557 antagonist Substances 0.000 title 1
VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 title 1
229960003638 dopamine Drugs 0.000 title 1
239000002464 receptor antagonist Substances 0.000 title 1
229940044551 receptor antagonist Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Biomedical Technology (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IDP971778A 1996-05-29 1997-05-28 Antagonis antagonis reseptor d4 dopamin benzoksazinon ID17266A (id)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1838396P	1996-05-29	1996-05-29
US4020897P	1997-03-06	1997-03-06

Publications (1)

Publication Number	Publication Date
ID17266A true ID17266A (id)	1997-12-18

Family

ID=26691052

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDP971778A ID17266A (id)	1996-05-29	1997-05-28	Antagonis antagonis reseptor d4 dopamin benzoksazinon

Country Status (36)

Country	Link
EP (1)	EP0906294B1 (id)
JP (1)	JP2000511534A (id)
KR (1)	KR20000016151A (id)
CN (1)	CN1074764C (id)
AR (1)	AR008372A1 (id)
AT (1)	ATE231846T1 (id)
AU (1)	AU731104B2 (id)
BG (1)	BG64049B1 (id)
BR (1)	BR9709630A (id)
CA (1)	CA2253406A1 (id)
CO (1)	CO4940505A1 (id)
CZ (1)	CZ384698A3 (id)
DE (1)	DE69718786T2 (id)
DK (1)	DK0906294T3 (id)
EA (1)	EA001486B1 (id)
EE (1)	EE03686B1 (id)
ES (1)	ES2191180T3 (id)
GE (1)	GEP20012389B (id)
HN (1)	HN1997000075A (id)
HR (1)	HRP970301B1 (id)
HU (1)	HUP9903758A3 (id)
ID (1)	ID17266A (id)
IL (1)	IL126895A (id)
NO (1)	NO312296B1 (id)
NZ (1)	NZ332737A (id)
PA (1)	PA8431101A1 (id)
PE (1)	PE69398A1 (id)
PL (1)	PL330195A1 (id)
PT (1)	PT906294E (id)
RO (1)	RO120845B1 (id)
SI (1)	SI0906294T1 (id)
SK (1)	SK282703B6 (id)
SV (1)	SV1997000047A (id)
TW (1)	TW542833B (id)
UY (1)	UY24569A1 (id)
WO (1)	WO1997045419A1 (id)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6177422B1 (en)	1996-05-29	2001-01-23	Warner-Lambert Company	Benzoxazinone dopamine D4 receptor antagonists
GB9801392D0 (en) *	1998-01-22	1998-03-18	Smithkline Beecham Plc	Novel compounds
US6177566B1 (en)	1998-06-30	2001-01-23	Neurogen Corporation	6-(4-arylalkylpiperazin-1-yl) benzodioxane and 6-(4-arylalkylpiperazin-1-yl) chromane derivatives: dopamine receptor subtype specific ligands
CA2336089A1 (en) *	1998-06-30	2000-01-06	Neurogen Corporation	6-(4-arylalkylpiperazin-1-yl)benzodioxane and 6-(4-arylalkylpiperazin-1-yl)chromane derivatives: dopamine receptor subtype specific ligands
US6291463B1 (en)	1998-06-30	2001-09-18	Neurogen Corporation	1-(Benzothiazol-2-yl)-4-(1-phenylmethyl) piperazines: dopamine receptor subtype specific ligands
WO2000000482A1 (en) *	1998-06-30	2000-01-06	Neurogen Corporation	1-(benzothiazol-2-yl)-4-(1-phenylmethyl)piperazines: dopamine receptor subtype specific ligands
DE19844291A1 (de)	1998-09-18	2000-03-23	Schering Ag	Benzoxazin- und Benzothiazin-Derivate und deren Verwendung in Arzneimitteln
GB9912411D0 (en) *	1999-05-28	1999-07-28	Pfizer Ltd	Compounds useful in therapy
US6939871B2 (en) *	2000-10-26	2005-09-06	Smithkline Beecham P.L.C.	Benzoxazinone derivatives, their preparation and use
GB0203804D0 (en)	2002-02-18	2002-04-03	Glaxo Group Ltd	Compounds
GB0209244D0 (en) *	2002-04-23	2002-06-05	Glaxo Group Ltd	Compounds
GB0227240D0 (en) *	2002-11-21	2002-12-31	Glaxo Group Ltd	Compounds
ES2232292B1 (es) *	2003-07-30	2006-11-01	Laboratorios Del Dr. Esteve, S.A.	Compuestos sulfonamidicos derivados de benzoxazinona, su preparacion y uso como medicamentos.
CN100455573C (zh) *	2005-11-11	2009-01-28	华东理工大学	一种制备1,4-苯并噁唑嗪-3-酮化合物的微波合成方法
KR200482995Y1 (ko)	2015-08-19	2017-03-23	이현진	물 공급부를 구비하는 얼음 트레이
CN116601148A (zh) *	2021-04-23	2023-08-15	上海翰森生物医药科技有限公司	杂环类衍生物抑制剂、其制备方法和应用
US20250214980A1 (en)	2022-03-14	2025-07-03	Slap Pharmaceuticals Llc	Multicyclic compounds
EP4514795A4 (en) *	2022-04-28	2025-12-31	Ningbo Newbay Tech Development Co Ltd	COMPOUNDS USED AS PARP1 INHIBITORS
CN117903159A (zh) *	2022-12-30	2024-04-19	成都硕德药业有限公司	一种内酰胺类衍生物、其制备方法及用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4613598A (en) *	1984-03-13	1986-09-23	Mitsubishi Chemical Industries Limited	Piperazine derivatives and their acid addition salts
EP0233728A1 (en) *	1986-02-11	1987-08-26	Takeda Chemical Industries, Ltd.	1,4-Benzoxazine derivatives their production and use
ATE171162T1 (de) *	1992-08-06	1998-10-15	Smithkline Beecham Plc	5-(2-oxyphenyl)-pyrrol-derivate als dopamin-d3- rezeptor-antagonisten

1997
- 1997-05-20 SI SI9730482T patent/SI0906294T1/xx unknown
- 1997-05-20 CZ CZ983846A patent/CZ384698A3/cs unknown
- 1997-05-20 SK SK1627-98A patent/SK282703B6/sk unknown
- 1997-05-20 ES ES97925651T patent/ES2191180T3/es not_active Expired - Lifetime
- 1997-05-20 EE EE9800417A patent/EE03686B1/xx not_active IP Right Cessation
- 1997-05-20 BR BR9709630A patent/BR9709630A/pt not_active Application Discontinuation
- 1997-05-20 DE DE69718786T patent/DE69718786T2/de not_active Expired - Fee Related
- 1997-05-20 AT AT97925651T patent/ATE231846T1/de not_active IP Right Cessation
- 1997-05-20 JP JP09542647A patent/JP2000511534A/ja not_active Ceased
- 1997-05-20 GE GEAP19974623A patent/GEP20012389B/en unknown
- 1997-05-20 NZ NZ332737A patent/NZ332737A/en unknown
- 1997-05-20 EP EP97925651A patent/EP0906294B1/en not_active Expired - Lifetime
- 1997-05-20 KR KR1019980709719A patent/KR20000016151A/ko not_active Ceased
- 1997-05-20 HU HU9903758A patent/HUP9903758A3/hu unknown
- 1997-05-20 PL PL97330195A patent/PL330195A1/xx unknown
- 1997-05-20 IL IL12689597A patent/IL126895A/en not_active IP Right Cessation
- 1997-05-20 EA EA199800987A patent/EA001486B1/ru not_active IP Right Cessation
- 1997-05-20 WO PCT/US1997/008524 patent/WO1997045419A1/en not_active Ceased
- 1997-05-20 PT PT97925651T patent/PT906294E/pt unknown
- 1997-05-20 DK DK97925651T patent/DK0906294T3/da active
- 1997-05-20 CA CA002253406A patent/CA2253406A1/en not_active Abandoned
- 1997-05-20 RO RO98-01622A patent/RO120845B1/ro unknown
- 1997-05-20 CN CN97195015A patent/CN1074764C/zh not_active Expired - Fee Related
- 1997-05-20 AU AU30727/97A patent/AU731104B2/en not_active Ceased
- 1997-05-22 HN HN1997000075A patent/HN1997000075A/es unknown
- 1997-05-27 AR ARP970102249A patent/AR008372A1/es unknown
- 1997-05-28 PE PE1997000432A patent/PE69398A1/es not_active Application Discontinuation
- 1997-05-28 SV SV1997000047A patent/SV1997000047A/es not_active Application Discontinuation
- 1997-05-28 ID IDP971778A patent/ID17266A/id unknown
- 1997-05-28 PA PA19978431101A patent/PA8431101A1/es unknown
- 1997-05-28 CO CO97029474A patent/CO4940505A1/es unknown
- 1997-05-28 TW TW086107221A patent/TW542833B/zh active
- 1997-05-28 UY UY24569A patent/UY24569A1/es not_active Application Discontinuation
- 1997-05-29 HR HR970301A patent/HRP970301B1/xx not_active IP Right Cessation
1998
- 1998-11-26 BG BG102959A patent/BG64049B1/bg unknown
- 1998-11-27 NO NO19985531A patent/NO312296B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR20000016151A (ko)	2000-03-25
PA8431101A1 (es)	2001-12-14
PE69398A1 (es)	1998-12-02
SK162798A3 (en)	1999-06-11
DE69718786T2 (de)	2003-10-23
IL126895A0 (en)	1999-09-22
HK1019737A1 (en)	2000-02-25
DK0906294T3 (da)	2003-05-05
SV1997000047A (es)	1998-08-13
HRP970301A2 (en)	1998-04-30
TW542833B (en)	2003-07-21
BR9709630A (pt)	1999-08-10
JP2000511534A (ja)	2000-09-05
HN1997000075A (es)	1997-07-30
DE69718786D1 (de)	2003-03-06
AU3072797A (en)	1998-01-05
HRP970301B1 (en)	2002-08-31
GEP20012389B (en)	2001-03-25
EA199800987A1 (ru)	1999-06-24
CO4940505A1 (es)	2000-07-24
ATE231846T1 (de)	2003-02-15
NO312296B1 (no)	2002-04-22
WO1997045419A1 (en)	1997-12-04
NZ332737A (en)	2000-06-23
NO985531D0 (no)	1998-11-27
NO985531L (no)	1998-11-27
CA2253406A1 (en)	1997-12-04
AU731104B2 (en)	2001-03-22
SI0906294T1 (en)	2003-04-30
PT906294E (pt)	2003-06-30
AR008372A1 (es)	2000-01-19
EP0906294A1 (en)	1999-04-07
PL330195A1 (en)	1999-04-26
BG64049B1 (bg)	2003-11-28
EP0906294B1 (en)	2003-01-29
IL126895A (en)	2001-06-14
HUP9903758A3 (en)	2000-07-28
HUP9903758A2 (hu)	2000-06-28
UY24569A1 (es)	2001-08-27
BG102959A (en)	1999-08-31
EE03686B1 (et)	2002-04-15
EA001486B1 (ru)	2001-04-23
CN1074764C (zh)	2001-11-14
CZ384698A3 (cs)	1999-03-17
ES2191180T3 (es)	2003-09-01
EE9800417A (et)	1999-06-15
RO120845B1 (ro)	2006-08-30
SK282703B6 (sk)	2002-11-06
CN1219930A (zh)	1999-06-16

Publication	Publication Date	Title
ID19623A (id)	1998-07-23	Antagonis reseptor vitronektin
ID18003A (id)	1998-02-19	Antagonis muskarinik
ID16742A (id)	1997-11-06	Antagonis reseptor endotelin
DE69812096D1 (de)	2003-04-17	Neuropeptid y rezeptorantagonisten
FI955223A7 (fi)	1996-05-03	Adheesioreseptoriantagonisteja
DK1009732T3 (da)	2003-09-22	1-Amino-alkylcyclohexan NMDA receptor antagonister
NO986110D0 (no)	1998-12-23	IL-8 reseptor-antagonister
NO986109D0 (no)	1998-12-23	IL-8 reseptor-antagonister
FI970107L (fi)	1997-03-07	Heterosyklisiä takykiniinireseptoriantagonisteja
EP0986385A4 (en)	2001-05-16	GONADORELIN ANTAGONISTS
EP0866705A4 (en)	1999-03-03	FIBRINOGENIC RECEPTOR ANTAGONISTS
EP0885205A4 (en)	2002-11-27	Fibrinogen Receptor Antagonists
NO990668L (no)	1999-04-12	IL-8 reseptor antagonister
FI960516A7 (fi)	1996-08-07	Substituoituja bifenyylisulfonamidiendoteliiniantagonisteja
TR199600359A2 (tr)	1996-11-21	Adezyon reseptörü antagonistleri.
ID24726A (id)	2000-08-03	Antagonis-antagonis reseptor trombin
DK0906294T3 (da)	2003-05-05	Benzoxazinon-dopamin D4-receptor-antagonister
NO950606D0 (no)	1995-02-17	Adhesjonsreseptor-antagonister
ID26223A (id)	2000-12-07	Antagonis reseptor vitronektin
ID19245A (id)	1998-06-28	Antagonis reseptor vitronektin, pembuatannya dan pemakaiannya
ID24162A (id)	2000-07-13	Antagonis-antagonis reseptor vitronektin
TR199501389A2 (tr)	1996-07-21	Adesyon reseptörü antagonistleri (karsitlari).
ID22838A (id)	1999-12-09	Oksazolidina sebagai antagonis 5-ht2a
DZ2322A1 (fr)	2002-12-28	Antagonistes de récepteurs de vitronectine.
ID28811A (id)	2001-07-05	Antagonis reseptor vitronektin