ID19245A - Antagonis reseptor vitronektin, pembuatannya dan pemakaiannya - Google Patents

Antagonis reseptor vitronektin, pembuatannya dan pemakaiannya

Info

Publication number
ID19245A
ID19245A IDP973917A ID973917A ID19245A ID 19245 A ID19245 A ID 19245A ID P973917 A IDP973917 A ID P973917A ID 973917 A ID973917 A ID 973917A ID 19245 A ID19245 A ID 19245A
Authority
ID
Indonesia
Prior art keywords
vitronektin
production
receptor antagonists
antagonists
receptor
Prior art date
Application number
IDP973917A
Other languages
English (en)
Inventor
Volkmar Dr Wehner
Hans Ulrich Dr Stilz
Anuschirwan Dr Peyman
Karlheinz Dr Scheunemann
Jean-Marie Dr Ruxer
Denis Dr Carniato
Jean-Michel Lefrancois
Thomas Richard Dr Gadek
Robert Dr Mcdowell
Original Assignee
Hoechst Ag
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag, Genentech Inc filed Critical Hoechst Ag
Publication of ID19245A publication Critical patent/ID19245A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IDP973917A 1996-12-20 1997-12-18 Antagonis reseptor vitronektin, pembuatannya dan pemakaiannya ID19245A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19653645A DE19653645A1 (de) 1996-12-20 1996-12-20 Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung

Publications (1)

Publication Number Publication Date
ID19245A true ID19245A (id) 1998-06-28

Family

ID=7815760

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP973917A ID19245A (id) 1996-12-20 1997-12-18 Antagonis reseptor vitronektin, pembuatannya dan pemakaiannya

Country Status (19)

Country Link
US (1) US5990145A (id)
EP (1) EP0854145A3 (id)
JP (1) JPH10182617A (id)
KR (1) KR19980064419A (id)
CN (1) CN1200373A (id)
AR (1) AR010369A1 (id)
AU (1) AU729760B2 (id)
BR (1) BR9706386A (id)
CA (1) CA2225267A1 (id)
CZ (1) CZ411297A3 (id)
DE (1) DE19653645A1 (id)
HU (1) HUP9702509A3 (id)
ID (1) ID19245A (id)
IL (1) IL122643A0 (id)
NO (1) NO975975L (id)
NZ (1) NZ329429A (id)
PL (1) PL323968A1 (id)
TR (1) TR199701645A2 (id)
ZA (1) ZA9711315B (id)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19647380A1 (de) * 1996-11-15 1998-05-20 Hoechst Ag 5-Ring-Heterocyclen als Inhibitoren der Leukozytenadhäsion und VLA-4-Antagonisten
BR9916536A (pt) 1998-12-23 2002-01-02 Searle & Co Método para o tratamento ou prevenção de um distúrbio de neoplasia em um mamìfero em necessidade deste tratamento ou prevenção, e, combinação
US6545032B1 (en) 1999-09-17 2003-04-08 Torrey Pines Institute For Molecular Studies Synthesis of [3,5,7]-H-imidazo[1,5-a] imidazol-2(3H)-one compounds
DE10028575A1 (de) 2000-06-14 2002-03-14 Basf Ag Integrinliganden
JP4250423B2 (ja) * 2001-03-19 2009-04-08 大日本住友製薬株式会社 アリール置換脂環式化合物及びそれを含有する医薬組成物
WO2002085405A2 (en) 2001-04-24 2002-10-31 Merck Patent Gmbh COMBINATION THERAPY USING ANTI-ANGIOGENIC AGENTS AND TNF$g(a)
EP1443963B1 (en) 2001-10-22 2014-05-21 The Scripps Research Institute Antibody targeting compounds
PT1443937E (pt) 2001-11-13 2008-09-23 Ortho Mcneil Janssen Pharm 1,4-benzodiazepinas substituídas e as suas utilizações para o tratamento de cancro
US7205315B2 (en) * 2003-09-27 2007-04-17 Sanofi-Aventis Deutschland Gmbh Bicyclic imino acid derivatives as inhibitors of matrix metalloproteinases
WO2007048127A2 (en) * 2005-10-20 2007-04-26 The Scripps Research Institute Fc labeling for immunostaining and immunotargeting
US8618115B2 (en) * 2005-10-26 2013-12-31 Bristol-Myers Squibb Company Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them
AU2007207465B2 (en) 2006-01-18 2012-12-06 Merck Patent Gmbh Specific therapy using integrin ligands for treating cancer
US7553836B2 (en) * 2006-02-06 2009-06-30 Bristol-Myers Squibb Company Melanin concentrating hormone receptor-1 antagonists
CN101588812A (zh) 2007-01-18 2009-11-25 默克专利有限公司 使用整联蛋白配体治疗癌的特异疗法和药物
JP2010520875A (ja) 2007-03-09 2010-06-17 レノビス， インコーポレイテッド Ｐ２ｘ７調節因子としてのビシクロヘテロアリール化合物およびその使用
PE20091928A1 (es) * 2008-05-29 2009-12-31 Bristol Myers Squibb Co Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos
EP2395992A2 (en) 2009-02-10 2011-12-21 The Scripps Research Institute Chemically programmed vaccination
NZ597339A (en) 2009-05-25 2013-10-25 Merck Patent Gmbh Continuous administration of cilengitide in cancer treatments
SG11201609050UA (en) 2014-05-30 2016-12-29 Pfizer Carbonitrile derivatives as selective androgen receptor modulators
WO2023275715A1 (en) 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU666318B2 (en) * 1991-06-28 1996-02-08 Smithkline Beecham Corporation Bicyclic fibrinogen antagonists
US5204350A (en) * 1991-08-09 1993-04-20 Merck & Co., Inc. Method of inhibiting osteoclast-mediated bone resorption by administration of n-heterocyclicalkyl-substituted phenyl derivatives
US5217994A (en) * 1991-08-09 1993-06-08 Merck & Co., Inc. Method of inhibiting osteoclast-mediated bone resorption by administration of aminoalkyl-substituted phenyl derivatives
DE4129603A1 (de) * 1991-09-06 1993-03-11 Thomae Gmbh Dr K Kondensierte 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
AU674553B2 (en) * 1992-10-14 1997-01-02 Merck & Co., Inc. Fibrinogen receptor antagonists
JPH08504194A (ja) * 1992-12-01 1996-05-07 メルク エンド カンパニー インコーポレーテッド フィブリノーゲンレセプターアンタゴニスト
NZ314922A (en) * 1992-12-21 1998-11-25 Smithkline Beecham Corp Benzodiazepinones; nitrogen containing heterocyclic intermediates and pharmaceutical compositions
US5563158A (en) * 1993-12-28 1996-10-08 The Dupont Merck Pharmaceutical Company Aromatic compounds containing basic and acidic termini useful as fibrinogen receptor antagonists
JPH10501222A (ja) * 1994-05-27 1998-02-03 メルク エンド カンパニー インコーポレーテッド 破骨細胞仲介骨吸収を抑制するための化合物
EP0762882A4 (en) * 1994-06-29 2002-09-11 Smithkline Beecham Corp Vibronectin Receptor Antagonists
EP0767792A4 (en) * 1994-06-29 2002-11-20 Smithkline Beecham Corp VITRONECTIN RECEPTOR ANTAGONISTS
WO1996026190A1 (en) * 1995-02-22 1996-08-29 Smithkline Beecham Corporation Integrin receptor antagonists
DE19516483A1 (de) * 1995-05-05 1996-11-07 Merck Patent Gmbh Adhäsionsrezeptor-Antagonisten
PT910563E (pt) * 1995-06-29 2003-09-30 Smithkline Beecham Corp Antagonistas de receptores de integrina
EP0895475A4 (en) * 1995-12-29 2000-08-23 Smithkline Beecham Corp VITRONECTIN RECEPTOR ANTAGONISTS
JP2000502704A (ja) * 1995-12-29 2000-03-07 スミスクライン・ビーチャム・コーポレイション ビトロネクチン受容体拮抗物質
PL327694A1 (en) * 1995-12-29 1998-12-21 Smithkline Beecham Corp Antagonists of vitronectin receptor
EP0796855B1 (de) * 1996-03-20 2002-02-06 Hoechst Aktiengesellschaft Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten
DE19629817A1 (de) * 1996-07-24 1998-01-29 Hoechst Ag Neue Imino-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten
DE19629816A1 (de) * 1996-07-24 1998-01-29 Hoechst Ag Neue Cycloalkyl-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten

Also Published As

Publication number Publication date
HUP9702509A3 (en) 2001-04-28
CZ411297A3 (cs) 1998-07-15
KR19980064419A (ko) 1998-10-07
CN1200373A (zh) 1998-12-02
EP0854145A3 (de) 2000-03-22
ZA9711315B (en) 1998-06-22
JPH10182617A (ja) 1998-07-07
HU9702509D0 (en) 1998-03-02
CA2225267A1 (en) 1998-06-20
NO975975L (no) 1998-06-22
DE19653645A1 (de) 1998-06-25
EP0854145A2 (de) 1998-07-22
MX9710389A (es) 1998-08-30
NO975975D0 (no) 1997-12-19
TR199701645A3 (tr) 1998-07-21
HUP9702509A2 (hu) 1999-06-28
AR010369A1 (es) 2000-06-07
IL122643A0 (en) 1998-08-16
AU729760B2 (en) 2001-02-08
BR9706386A (pt) 2003-04-22
TR199701645A2 (xx) 1998-07-21
US5990145A (en) 1999-11-23
PL323968A1 (en) 1998-06-22
AU4846497A (en) 1998-06-25
NZ329429A (en) 1999-05-28

Similar Documents

Publication Publication Date Title
ID19253A (id) Bahan antagonis reseptor vitronektin, pembuatannya dan penggunaannya
ID26099A (id) Turunan amida dan antagonis nosiseptin
ID19245A (id) Antagonis reseptor vitronektin, pembuatannya dan pemakaiannya
PT1009732E (pt) 1-amino-alquilciclo-hexanos antagonistas do receptor nmda
ID28846A (id) 2-fenilbenzimidazol dan 2_fenilindol, pembuatan dan penggunaanya
DE69734833D1 (de) Vitronektin rezeptor antagonisten
DK0738150T3 (da) Bicykliske fibrinogene antagonister
FI955223L (fi) Adheesioreseptoriantagonisteja
ID26305A (id) Benzamida tersubstitusi baru, pembuatan dan penggunaannya
PT1131291E (pt) Antagonistas iii do receptor 4-aroil-piperidin-ccr-3
ID27757A (id) Indolinona-indolinona tersubstitusi baru, preparasi dan penggunaannya sebagai obat
ID16742A (id) Antagonis reseptor endotelin
EP0866705A4 (en) FIBRINOGENIC RECEPTOR ANTAGONISTS
ATE235467T1 (de) Antagonisten des vitronectin-rezeptors
ID22916A (id) Turunan-turunan ergolin dan penggunaannya sebagai antagonis reseptor somatostatin
ID24714A (id) Turunan tiazolidindion tersubstitusi, proses pembuatannya dan penggunaan bahan farmasinya
IS5295A (is) Azetidínýlprópýlpíperidín afleiður, milliefni og notkun sem mótlyf gegn kínínhröðun
ID24726A (id) Antagonis-antagonis reseptor trombin
ID27544A (id) Agonis dan antagonis muskarinat
ID17266A (id) Antagonis antagonis reseptor d4 dopamin benzoksazinon
ID26223A (id) Antagonis reseptor vitronektin
ID24162A (id) Antagonis-antagonis reseptor vitronektin
ID22838A (id) Oksazolidina sebagai antagonis 5-ht2a
ID24633A (id) Turunan tetrahidropirimidinon 3-tersubstitusi, pembuatan dan penggunaannya
ID30484A (id) Turunan 4-heterosikliksulfonamidil 6 metoksi 5 (2 metoksi fenoksi) 2 piridil-pirimidin, pembuatannya dan penggunaan sebagai antagonis reseptor endotelin