ID19074A - Sediaan rekombinan faktor viii bebas albumin dengan isi gula rendah yang berimbang - Google Patents

Sediaan rekombinan faktor viii bebas albumin dengan isi gula rendah yang berimbang

Info

Publication number
ID19074A
ID19074A IDP972395A ID972395A ID19074A ID 19074 A ID19074 A ID 19074A ID P972395 A IDP972395 A ID P972395A ID 972395 A ID972395 A ID 972395A ID 19074 A ID19074 A ID 19074A
Authority
ID
Indonesia
Prior art keywords
recommination
albumin
ready
sugar contents
free factor
Prior art date
Application number
IDP972395A
Other languages
English (en)
Indonesian (id)
Inventor
Rajiv Nayar
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ID19074A publication Critical patent/ID19074A/id

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IDP972395A 1996-07-12 1997-07-10 Sediaan rekombinan faktor viii bebas albumin dengan isi gula rendah yang berimbang ID19074A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/678,492 US5763401A (en) 1996-07-12 1996-07-12 Stabilized albumin-free recombinant factor VIII preparation having a low sugar content

Publications (1)

Publication Number Publication Date
ID19074A true ID19074A (id) 1998-06-11

Family

ID=24723010

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP972395A ID19074A (id) 1996-07-12 1997-07-10 Sediaan rekombinan faktor viii bebas albumin dengan isi gula rendah yang berimbang

Country Status (30)

Country Link
US (2) US5763401A (fr)
EP (1) EP0818204B1 (fr)
JP (1) JP4077055B2 (fr)
KR (1) KR100491281B1 (fr)
CN (1) CN1130224C (fr)
AR (1) AR007845A1 (fr)
AT (1) ATE191146T1 (fr)
AU (1) AU718901B2 (fr)
BR (1) BR9704407B1 (fr)
CA (1) CA2210038C (fr)
CO (1) CO4700302A1 (fr)
CZ (1) CZ292183B6 (fr)
DE (1) DE69701548T2 (fr)
DK (1) DK0818204T3 (fr)
ES (1) ES2144293T3 (fr)
GR (1) GR3033669T3 (fr)
HU (1) HU221415B1 (fr)
ID (1) ID19074A (fr)
IL (1) IL121273A (fr)
MY (1) MY125544A (fr)
NZ (1) NZ328297A (fr)
PL (1) PL186950B1 (fr)
PT (1) PT818204E (fr)
RU (1) RU2201252C2 (fr)
SG (1) SG50864A1 (fr)
SK (1) SK282207B6 (fr)
TR (1) TR199700628A2 (fr)
TW (1) TW381027B (fr)
UA (1) UA43882C2 (fr)
ZA (1) ZA976167B (fr)

Families Citing this family (71)

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US5763401A (en) * 1996-07-12 1998-06-09 Bayer Corporation Stabilized albumin-free recombinant factor VIII preparation having a low sugar content
EP1820516B1 (fr) * 1999-02-22 2013-07-24 University of Connecticut Nouvelles formulations de facteur VIII sans albumine
US7601691B2 (en) 1999-05-17 2009-10-13 Conjuchem Biotechnologies Inc. Anti-obesity agents
US20040266673A1 (en) * 2002-07-31 2004-12-30 Peter Bakis Long lasting natriuretic peptide derivatives
US6887470B1 (en) 1999-09-10 2005-05-03 Conjuchem, Inc. Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
KR20020072563A (ko) * 1999-12-30 2002-09-16 인터뮨, 인크. γ―ＩＦＮ 액체―소적 에어로졸 및 방법
US6689353B1 (en) 2000-06-28 2004-02-10 Bayer Pharmaceuticals Corporation Stabilized interleukin 2
JP2005530683A (ja) 2001-12-21 2005-10-13 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 第ｖｉｉ因子ポリペプチドの液体組成物
DE10211227A1 (de) * 2002-03-13 2003-10-02 Aventis Behring Gmbh Verfahren zur Rekonstitution von Iyophilisierten Proteinen
GB0207092D0 (en) 2002-03-26 2002-05-08 Sod Conseils Rech Applic Stable pharmaceutical composition containing factor VIII
CN101912601B (zh) 2002-06-21 2012-08-29 诺和诺德医疗保健公司 因子vii多肽的稳定化固体组合物
JP2006504772A (ja) * 2002-10-29 2006-02-09 アルザ・コーポレーション 安定化された固体ポリペプチド粒子
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JP5306597B2 (ja) * 2003-07-01 2013-10-02 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 第ｖｉｉ因子ポリペプチドの液体水性薬学的組成物
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US8541002B2 (en) 2003-09-12 2013-09-24 Agenus Inc. Vaccine for treatment and prevention of herpes simplex virus infection
AU2004288854B2 (en) * 2003-11-10 2009-10-01 Arriva-Pharmaceuticals, Inc. Dry recombinant human alpha 1-antitrypsin formulation
EP2311437A1 (fr) * 2003-12-19 2011-04-20 Novo Nordisk Health Care AG Compositions stabilisees de polypeptides de facteur VII
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ES2347902T3 (es) * 2004-04-23 2010-11-22 Conjuchem Biotechnologies Inc. Canadian Corporation 4528590 Fase solida para uso en un procedimiento para la purificacion de conjugados de albumina.
PL1750733T3 (pl) 2004-05-03 2014-05-30 Univ Emory Sposób podawania świńskiego czynnika krzepnięcia VIII pozbawionego domeny B
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EP2385825B1 (fr) 2008-11-07 2018-10-10 University of Connecticut Formulation de facteur viii
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DK2632478T3 (da) 2010-10-27 2019-10-07 Novo Nordisk As Behandling af diabetes melitus under anvendelse af insulinindsprøjtninger indgivet med varierende indsprøjtningsintervaller
BR112013011041B1 (pt) 2010-11-05 2021-05-25 Baxalta GmbH variante de fator viii, método para produzir uma variante de fviii, uso da variante de fator viii, e, composição farmacêutica
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CN108348458A (zh) * 2015-11-05 2018-07-31 诺和诺德股份有限公司 Fviii制剂
CN106139127B (zh) * 2016-08-05 2020-04-07 无锡药明生物技术股份有限公司 重组凝血因子ⅷ冻干制剂
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Also Published As

Publication number Publication date
TW381027B (en) 2000-02-01
US5763401A (en) 1998-06-09
ZA976167B (en) 1998-02-02
TR199700628A2 (xx) 1998-01-21
CZ292183B6 (cs) 2003-08-13
IL121273A0 (en) 1998-01-04
ES2144293T3 (es) 2000-06-01
JP4077055B2 (ja) 2008-04-16
EP0818204A3 (fr) 1998-02-04
CN1181974A (zh) 1998-05-20
HUP9701191A2 (hu) 1999-06-28
ATE191146T1 (de) 2000-04-15
PL321058A1 (en) 1998-01-19
DE69701548T2 (de) 2000-07-27
CZ219497A3 (cs) 1998-01-14
DE69701548D1 (de) 2000-05-04
DK0818204T3 (da) 2000-07-17
CA2210038A1 (fr) 1998-01-12
AU2860497A (en) 1998-01-22
BR9704407A (pt) 2000-06-06
UA43882C2 (uk) 2002-01-15
KR980008241A (ko) 1998-04-30
KR100491281B1 (ko) 2005-08-05
SK92197A3 (en) 1998-02-04
PT818204E (pt) 2000-08-31
MY125544A (en) 2006-08-30
IL121273A (en) 2000-09-28
EP0818204A2 (fr) 1998-01-14
CO4700302A1 (es) 1998-12-29
SG50864A1 (en) 1998-07-20
PL186950B1 (pl) 2004-04-30
AU718901B2 (en) 2000-04-20
CA2210038C (fr) 2007-03-13
EP0818204B1 (fr) 2000-03-29
AR007845A1 (es) 1999-11-24
MX9705209A (es) 1998-05-31
RU2201252C2 (ru) 2003-03-27
SK282207B6 (sk) 2001-12-03
GR3033669T3 (en) 2000-10-31
HU221415B1 (en) 2002-09-28
HUP9701191A3 (en) 2000-08-28
JPH1067679A (ja) 1998-03-10
HU9701191D0 (en) 1997-08-28
CN1130224C (zh) 2003-12-10
BR9704407B1 (pt) 2010-03-09
US5874408A (en) 1999-02-23
NZ328297A (en) 1999-09-29

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