ID21682A - Turunan-turunan pirolo [3,4-d] pirimidinon dan penggunaannya sebagai obat-obatan - Google Patents

Turunan-turunan pirolo [3,4-d] pirimidinon dan penggunaannya sebagai obat-obatan

Info

Publication number: ID21682A
Authority: ID; Indonesia
Prior art keywords: pct; pyramidinons; pirolo; medicines; sec
Prior art date: 1996-12-21

Application number

IDW990507A

Other languages

English (en)

Inventor

Martin Cooper

David Cheshire

David Donald

Mark Furber

Matthew Perry

Richard Harrison

Nicholas Tomkinson

Original Assignee

Astra Pharma Prod

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-21

Filing date

1997-12-18

Publication date

1999-07-08

1997-12-18 Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod

1999-07-08 Publication of ID21682A publication Critical patent/ID21682A/id

Links

239000003814 drug Substances 0.000 title 1
238000000034 method Methods 0.000 abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 2
-1 5-substituted pyrrolo[3,4-d]pyrimidine-2,4-diones Chemical class 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Dermatology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Neurology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Cardiology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Vascular Medicine (AREA)
Transplantation (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IDW990507A 1996-12-21 1997-12-18 Turunan-turunan pirolo [3,4-d] pirimidinon dan penggunaannya sebagai obat-obatan ID21682A (id)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9626643.2A GB9626643D0 (en)	1996-12-21	1996-12-21	Compounds

Publications (1)

Publication Number	Publication Date
ID21682A true ID21682A (id)	1999-07-08

Family

ID=10804862

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW990507A ID21682A (id)	1996-12-21	1997-12-18	Turunan-turunan pirolo [3,4-d] pirimidinon dan penggunaannya sebagai obat-obatan

Country Status (23)

Country	Link
US (8)	US6046204A (id)
EP (1)	EP0946562B1 (id)
JP (1)	JP2001507687A (id)
KR (1)	KR20000069605A (id)
CN (1)	CN1246119A (id)
AT (1)	ATE215088T1 (id)
AU (1)	AU717429B2 (id)
BR (1)	BR9714063A (id)
CA (1)	CA2275312A1 (id)
CZ (1)	CZ289925B6 (id)
DE (1)	DE69711430T2 (id)
EE (1)	EE9900315A (id)
GB (1)	GB9626643D0 (id)
HU (1)	HUP0002839A3 (id)
ID (1)	ID21682A (id)
IL (1)	IL130538A0 (id)
IS (1)	IS5082A (id)
NO (1)	NO993027L (id)
NZ (1)	NZ336124A (id)
PL (1)	PL334228A1 (id)
SK (1)	SK76699A3 (id)
TR (1)	TR199901433T2 (id)
WO (1)	WO1998028301A1 (id)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9801399D0 (sv)	1998-04-21	1998-04-21	Astra Pharma Prod	Method and apparatus for filling containers
WO2000042017A1 (en)	1999-01-15	2000-07-20	Byk Gulden Lomberg Chemische Fabrik Gmbh	Phenanthridine-n-oxides with pde-iv inhibiting activity
DE60033918D1 (de)	1999-01-15	2007-04-26	Altana Pharma Ag	Polysubstituted 6-phenylphenanthridines mit pde-iv hemmender wirkung
CA2359449A1 (en)	1999-01-15	2000-07-20	Beate Gutterer	Phenanthridine-n-oxides with pde-iv inhibiting activity
US6361486B1 (en) *	2000-02-29	2002-03-26	Agilent Technologies, Inc.	Coaxial-drive centrifuge providing tilt control relative to centrifugal force
US20070105841A1 (en) *	2000-08-14	2007-05-10	Breitenbucher J G	Method for treating allergies using substituted pyrazoles
AU2001281255B2 (en) *	2000-08-14	2006-07-20	Ortho-Mcneil Pharmaceutical, Inc.	Substituted pyrazoles
TW200407315A (en) *	2002-04-23	2004-05-16	Sankyo Co	Pyrimidine derivatives
JP2006528515A (ja) *	2003-07-24	2006-12-21	テコメット・インコーポレーテッド	海綿状の構造体
WO2006115509A2 (en)	2004-06-24	2006-11-02	Novartis Vaccines And Diagnostics Inc.	Small molecule immunopotentiators and assays for their detection
MY140748A (en)	2004-12-06	2010-01-15	Astrazeneca Ab	Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy
US8198288B2 (en)	2006-05-04	2012-06-12	Pulmagen Therapeutics (Inflammation) Limited	Tetrahydropyrrolopyrimidinediones and their use in therapy
NZ572250A (en)	2006-05-04	2011-10-28	Pulmagen Therapeutics Inflammation Ltd	Tetrahydropyrrolopyrimidinediones and their use as human neutrophil elastase inhibitors
JP5453086B2 (ja)	2006-06-06	2014-03-26	イントラ−セルラー・セラピーズ・インコーポレイテッド	有機化合物
WO2009073210A1 (en)	2007-12-06	2009-06-11	Intra-Cellular Therapies, Inc	Organic compounds
WO2009100403A1 (en) *	2008-02-07	2009-08-13	Neurogen Corporation	Substituted aryl pyrimidinones
BRPI0922700A2 (pt)	2008-12-06	2015-08-11	Intracellular Therapies Inc	Compostos orgânicos
MX2011005935A (es)	2008-12-06	2011-12-16	Intra Cellular Therapies Inc	Compuestos organicos.
EA201170772A1 (ru)	2008-12-06	2012-03-30	Интра-Селлулар Терапиз, Инк.	Органические соединения
EP2464354B1 (en)	2009-08-10	2015-04-01	The Regents of The University of California	Pyrimido-pyrrolo-quinoxalinedione inhibitors of cystic fibrosis transmembrane conductance regulator protein and uses therefor
US9371327B2 (en)	2010-05-31	2016-06-21	Intra-Cellular Therapies, Inc.	PDE1 inhibitor compounds
US9434730B2 (en)	2010-05-31	2016-09-06	Intra-Cellular Therapies, Inc.	PDE1 inhibitor compounds
USRE48842E1 (en)	2011-05-27	2021-12-07	The Regents Of The University Of California	Pyrimido-pyrrolo-oxazine-dione compound inhibitors of the cystic fibrosis transmembrane conductance regulator protein and uses therefor
US9546175B2 (en)	2014-08-07	2017-01-17	Intra-Cellular Therapies, Inc.	Organic compounds
CN108129486B (zh) *	2018-01-25	2020-06-05	华东理工大学	嘧啶酮衍生物及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2436792A (en) *	1991-08-16	1993-03-16	Merck & Co., Inc.	Quinazoline derivatives as inhibitors of hiv reverse transcriptase
GB9424842D0 (en) *	1994-12-09	1995-02-08	British Tech Group	Pharmaceutical compositions

1996
- 1996-12-21 GB GBGB9626643.2A patent/GB9626643D0/en active Pending
1997
- 1997-12-18 HU HU0002839A patent/HUP0002839A3/hu unknown
- 1997-12-18 IL IL13053897A patent/IL130538A0/xx unknown
- 1997-12-18 DE DE69711430T patent/DE69711430T2/de not_active Expired - Fee Related
- 1997-12-18 EE EEP199900315A patent/EE9900315A/xx unknown
- 1997-12-18 WO PCT/SE1997/002157 patent/WO1998028301A1/en not_active Ceased
- 1997-12-18 JP JP52869798A patent/JP2001507687A/ja not_active Ceased
- 1997-12-18 PL PL97334228A patent/PL334228A1/xx unknown
- 1997-12-18 AU AU55809/98A patent/AU717429B2/en not_active Ceased
- 1997-12-18 SK SK766-99A patent/SK76699A3/sk unknown
- 1997-12-18 CZ CZ19992204A patent/CZ289925B6/cs not_active IP Right Cessation
- 1997-12-18 BR BR9714063-5A patent/BR9714063A/pt not_active IP Right Cessation
- 1997-12-18 US US09/011,780 patent/US6046204A/en not_active Expired - Fee Related
- 1997-12-18 TR TR1999/01433T patent/TR199901433T2/xx unknown
- 1997-12-18 NZ NZ336124A patent/NZ336124A/en unknown
- 1997-12-18 KR KR1019997005595A patent/KR20000069605A/ko not_active Withdrawn
- 1997-12-18 EP EP97952146A patent/EP0946562B1/en not_active Expired - Lifetime
- 1997-12-18 CN CN97181811A patent/CN1246119A/zh active Pending
- 1997-12-18 CA CA002275312A patent/CA2275312A1/en not_active Abandoned
- 1997-12-18 ID IDW990507A patent/ID21682A/id unknown
- 1997-12-18 AT AT97952146T patent/ATE215088T1/de active
1999
- 1999-06-14 IS IS5082A patent/IS5082A/is unknown
- 1999-06-18 NO NO993027A patent/NO993027L/no not_active Application Discontinuation
2000
- 2000-02-17 US US09/505,857 patent/US6136974A/en not_active Expired - Fee Related
- 2000-02-17 US US09/506,091 patent/US6229013B1/en not_active Expired - Fee Related
- 2000-02-17 US US09/505,862 patent/US6211368B1/en not_active Expired - Fee Related
- 2000-02-17 US US09/506,090 patent/US6166206A/en not_active Expired - Fee Related
- 2000-11-08 US US09/707,880 patent/US6306863B1/en not_active Expired - Fee Related
2001
- 2001-10-09 US US09/971,709 patent/US20020025966A1/en not_active Abandoned
2003
- 2003-03-05 US US10/378,913 patent/US20030162798A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CN1246119A (zh)	2000-03-01
EP0946562B1 (en)	2002-03-27
HUP0002839A3 (en)	2001-04-28
US20030162798A1 (en)	2003-08-28
TR199901433T2 (xx)	1999-09-21
KR20000069605A (ko)	2000-11-25
AU717429B2 (en)	2000-03-23
CA2275312A1 (en)	1998-07-02
EP0946562A1 (en)	1999-10-06
ATE215088T1 (de)	2002-04-15
SK76699A3 (en)	2000-05-16
US6046204A (en)	2000-04-04
US6211368B1 (en)	2001-04-03
US20020025966A1 (en)	2002-02-28
NO993027D0 (no)	1999-06-18
HUP0002839A2 (hu)	2001-02-28
NO993027L (no)	1999-08-20
US6229013B1 (en)	2001-05-08
BR9714063A (pt)	2002-01-02
GB9626643D0 (en)	1997-02-12
IL130538A0 (en)	2000-06-01
PL334228A1 (en)	2000-02-14
WO1998028301A1 (en)	1998-07-02
CZ220499A3 (cs)	2000-02-16
AU5580998A (en)	1998-07-17
US6306863B1 (en)	2001-10-23
NZ336124A (en)	2001-03-30
DE69711430D1 (de)	2002-05-02
CZ289925B6 (cs)	2002-04-17
DE69711430T2 (de)	2002-10-31
IS5082A (is)	1999-06-14
EE9900315A (et)	2000-02-15
US6136974A (en)	2000-10-24
JP2001507687A (ja)	2001-06-12
US6166206A (en)	2000-12-26

Publication	Publication Date	Title
EE9900315A (et)	2000-02-15	Pürrolo[3,4-d]pürimidinooni derivaadid ja nende kasutamine ravimitena
EE200000318A (et)	2001-08-15	Uudsed ühendid
SE9701398D0 (sv)	1997-04-15	Novel compounds
SE9702001D0 (sv)	1997-05-28	Novel compounds
ID24837A (id)	2000-08-24	Senyawa triazolo [4,5-d] pirimidina, penggunaan, komposisi dan proses pembuatannya
HUT75776A (en)	1997-05-28	Pyrazolo and pyrrolopyridines, their using, pharmaceutical compositions containing them and intermediates
ES2132383T3 (es)	1999-08-16	Inhibidores de proteasa hiv.
DE69804766D1 (de)	2002-05-16	Isoflavonderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
AU1929688A (en)	1989-01-27	Leukotriene antagonists, processes for the preparation thereof, the use thereof for the treatment of diseases, and precursors
ATE66468T1 (de)	1991-09-15	Leukotrienantagonisten, verfahren zu ihrer herstellung und ihre anwendung zur behandlung von krankheiten.
ATE221068T1 (de)	2002-08-15	Anellierte beta-carboline