ID22156A - Turunan substitusi benzosikloheptapiridina yang berguna untuk menghambat fernesil protein transferase - Google Patents

Turunan substitusi benzosikloheptapiridina yang berguna untuk menghambat fernesil protein transferase

Info

Publication number: ID22156A
Authority: ID; Indonesia
Prior art keywords: substitution; protein transferase; fernesil; benzosicloheptapiridina; inhibit
Prior art date: 1996-09-13

Application number

IDW990087A

Other languages

English (en)

Inventor

Arthur G Taveras

F George Njoroge

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-09-13

Filing date

1997-09-11

Publication date

1999-09-09

1997-09-11 Application filed by Schering Corp filed Critical Schering Corp

1999-09-09 Publication of ID22156A publication Critical patent/ID22156A/id

Links

102000004357 Transferases Human genes 0.000 title abstract 2
108090000992 Transferases Proteins 0.000 title abstract 2
238000006467 substitution reaction Methods 0.000 title 2
150000001875 compounds Chemical class 0.000 abstract 3
230000002159 abnormal effect Effects 0.000 abstract 1
210000004027 cell Anatomy 0.000 abstract 1
125000004030 farnesyl group Chemical group [H]C([*])([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
210000004881 tumor cell Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Enzymes And Modification Thereof (AREA)
Cosmetics (AREA)
Confectionery (AREA)
Indole Compounds (AREA)
Medicines Containing Plant Substances (AREA)

IDW990087A 1996-09-13 1997-09-11 Turunan substitusi benzosikloheptapiridina yang berguna untuk menghambat fernesil protein transferase ID22156A (id)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US71192596A	1996-09-13	1996-09-13

Publications (1)

Publication Number	Publication Date
ID22156A true ID22156A (id)	1999-09-09

Family

ID=24860067

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW990087A ID22156A (id)	1996-09-13	1997-09-11	Turunan substitusi benzosikloheptapiridina yang berguna untuk menghambat fernesil protein transferase

Country Status (20)

Country	Link
EP (1)	EP0931079B1 (id)
JP (1)	JP2001500508A (id)
KR (1)	KR20000036103A (id)
CN (1)	CN1122031C (id)
AT (1)	ATE209201T1 (id)
AU (1)	AU4337797A (id)
BR (1)	BR9711477A (id)
CA (1)	CA2264513C (id)
CZ (1)	CZ87499A3 (id)
DE (1)	DE69709774T2 (id)
ES (1)	ES2163195T3 (id)
HU (1)	HUP9904056A3 (id)
ID (1)	ID22156A (id)
IL (1)	IL128929A0 (id)
NO (1)	NO991229L (id)
NZ (1)	NZ334437A (id)
PL (1)	PL332253A1 (id)
SK (1)	SK33599A3 (id)
TR (1)	TR199901205T2 (id)
WO (1)	WO1998011099A1 (id)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998057948A1 (en) *	1997-06-17	1998-12-23	Schering Corporation	Novel n-substituted urea inhibitors of farnesyl-protein transferase
US6358968B1 (en)	1997-06-17	2002-03-19	Schering Corporation	N-substituted urea inhibitors of farnesyl-protein transferase
BR9910144A (pt)	1998-01-21	2002-04-02	Millennium Pharm Inc	Antagonistas de receptores de quimiocinas e seu uso
US6509346B2 (en)	1998-01-21	2003-01-21	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
US6613905B1 (en)	1998-01-21	2003-09-02	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
EP1047675A1 (en)	1998-01-21	2000-11-02	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
US6503926B2 (en)	1998-09-04	2003-01-07	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
US7271176B2 (en)	1998-09-04	2007-09-18	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use thereof
US6288083B1 (en)	1998-09-04	2001-09-11	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
US7541365B2 (en)	2001-11-21	2009-06-02	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
TWI291467B (en)	2002-11-13	2007-12-21	Millennium Pharm Inc	CCR1 antagonists and methods of use therefor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5719148A (en) *	1993-10-15	1998-02-17	Schering Corporation	Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
IL111235A (en) *	1993-10-15	2001-03-19	Schering Plough Corp	Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
DE69635424T2 (de) *	1995-12-22	2006-08-03	Schering Corp.	Zur hemming der g-protein-funktion und zur behandlung proliferativer krankheiten geeignete tricyclische amide

1997
- 1997-09-11 AT AT97941478T patent/ATE209201T1/de not_active IP Right Cessation
- 1997-09-11 DE DE69709774T patent/DE69709774T2/de not_active Expired - Fee Related
- 1997-09-11 PL PL97332253A patent/PL332253A1/xx unknown
- 1997-09-11 WO PCT/US1997/015905 patent/WO1998011099A1/en not_active Ceased
- 1997-09-11 JP JP10513763A patent/JP2001500508A/ja not_active Ceased
- 1997-09-11 KR KR1019997002125A patent/KR20000036103A/ko not_active Withdrawn
- 1997-09-11 EP EP97941478A patent/EP0931079B1/en not_active Expired - Lifetime
- 1997-09-11 HU HU9904056A patent/HUP9904056A3/hu unknown
- 1997-09-11 CA CA002264513A patent/CA2264513C/en not_active Expired - Fee Related
- 1997-09-11 NZ NZ334437A patent/NZ334437A/xx unknown
- 1997-09-11 CN CN97199527A patent/CN1122031C/zh not_active Expired - Fee Related
- 1997-09-11 SK SK335-99A patent/SK33599A3/sk unknown
- 1997-09-11 CZ CZ99874A patent/CZ87499A3/cs unknown
- 1997-09-11 AU AU43377/97A patent/AU4337797A/en not_active Abandoned
- 1997-09-11 BR BR9711477A patent/BR9711477A/pt unknown
- 1997-09-11 IL IL12892997A patent/IL128929A0/xx unknown
- 1997-09-11 ID IDW990087A patent/ID22156A/id unknown
- 1997-09-11 TR TR1999/01205T patent/TR199901205T2/xx unknown
- 1997-09-11 ES ES97941478T patent/ES2163195T3/es not_active Expired - Lifetime
1999
- 1999-03-12 NO NO991229A patent/NO991229L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0931079A1 (en)	1999-07-28
JP2001500508A (ja)	2001-01-16
SK33599A3 (en)	2000-03-13
IL128929A0 (en)	2000-02-17
DE69709774D1 (de)	2002-02-21
CZ87499A3 (cs)	1999-08-11
HUP9904056A2 (hu)	2000-04-28
CA2264513A1 (en)	1998-03-19
NZ334437A (en)	2000-09-29
CA2264513C (en)	2004-03-30
CN1122031C (zh)	2003-09-24
DE69709774T2 (de)	2002-08-08
NO991229L (no)	1999-05-12
TR199901205T2 (xx)	1999-07-21
ES2163195T3 (es)	2002-01-16
BR9711477A (pt)	1999-08-24
AU4337797A (en)	1998-04-02
ATE209201T1 (de)	2001-12-15
HUP9904056A3 (en)	2001-10-29
WO1998011099A1 (en)	1998-03-19
KR20000036103A (ko)	2000-06-26
EP0931079B1 (en)	2001-11-21
CN1236364A (zh)	1999-11-24
PL332253A1 (en)	1999-08-30
HK1018443A1 (en)	1999-12-24
NO991229D0 (no)	1999-03-12

Publication	Publication Date	Title
ID21699A (id)	1999-07-15	Penghambat-penghambat trisiklik dari transferase protein farnesil
ATE282036T1 (de)	2004-11-15	Trizyklische antitumor verbindungen mit farnesyl protein transferase inhibierender wirkung
ID22156A (id)	1999-09-09	Turunan substitusi benzosikloheptapiridina yang berguna untuk menghambat fernesil protein transferase
ID21577A (id)	1999-06-24	Komposisi-komposisi yang berguna untuk tranferase protein farnesil
ID22067A (id)	1999-08-26	Senyawa-senyawa yang berguna untuk inhibisi transferase protein farnesil
ID22002A (id)	1999-08-19	Derivatif benzosikloheptapiridin tersubstitusi yang berguna untuk penghalangan transferase protein farnesil