ID25698A - Proses pembuatan granul semprot yang mengandung riboflavin - Google Patents

Proses pembuatan granul semprot yang mengandung riboflavin

Info

Publication number
ID25698A
ID25698A IDP20000337A ID20000337A ID25698A ID 25698 A ID25698 A ID 25698A ID P20000337 A IDP20000337 A ID P20000337A ID 20000337 A ID20000337 A ID 20000337A ID 25698 A ID25698 A ID 25698A
Authority
ID
Indonesia
Prior art keywords
granul
making
spray drying
drying process
spray containing
Prior art date
Application number
IDP20000337A
Other languages
English (en)
Inventor
Markus Nowotny
Jean-Claude Tritsch
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8238078&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ID25698(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ID25698A publication Critical patent/ID25698A/id

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/12—Heterocyclic compounds containing pteridine ring systems containing pteridine ring systems condensed with carbocyclic rings or ring systems
    • C07D475/14—Benz [g] pteridines, e.g. riboflavin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IDP20000337A 1999-04-30 2000-04-26 Proses pembuatan granul semprot yang mengandung riboflavin ID25698A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99108476 1999-04-30

Publications (1)

Publication Number Publication Date
ID25698A true ID25698A (id) 2000-11-02

Family

ID=8238078

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP20000337A ID25698A (id) 1999-04-30 2000-04-26 Proses pembuatan granul semprot yang mengandung riboflavin

Country Status (16)

Country Link
US (1) US6723346B1 (id)
EP (1) EP1048668B2 (id)
JP (1) JP4965013B2 (id)
KR (1) KR100720202B1 (id)
CN (1) CN1198595C (id)
AT (1) ATE231864T1 (id)
AU (1) AU770320B2 (id)
BR (1) BR0002390A (id)
CA (1) CA2306502A1 (id)
DE (1) DE60001286T3 (id)
DK (1) DK1048668T3 (id)
ES (1) ES2189711T5 (id)
ID (1) ID25698A (id)
MX (1) MXPA00004185A (id)
NO (1) NO318219B1 (id)
TW (1) TWI253347B (id)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0219815D0 (en) * 2002-08-24 2002-10-02 Accentus Plc Preparation of small crystals
DE10317051A1 (de) 2003-04-11 2004-10-21 Basf Ag Verfahren zur Herstellung von Riboflavin der Modifikation B/C in Granulatform
ATE442369T1 (de) 2003-07-22 2009-09-15 Dsm Ip Assets Bv Verfahren zur aufreinigung von riboflavin
US8689459B2 (en) * 2006-12-07 2014-04-08 Friesland Brands B.V. Method and apparatus for spray drying and powder produced using said method
CN104961740B (zh) * 2015-06-02 2016-04-27 湖北广济药业股份有限公司 一种含核黄素的固体制剂及其制备方法
ES2949057T3 (es) 2018-11-07 2023-09-25 Dsm Ip Assets Bv Medicamentos con contenido en riboflavina que exhiben una fluidez mejorada

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0307767B1 (en) * 1987-09-18 1993-07-21 F. Hoffmann-La Roche Ag Novel form of riboflavin
DE3819745A1 (de) * 1988-06-10 1989-12-14 Basf Ag Verfahren zur herstellung von auf mikrobiellem wege hergestelltem riboflavin in form von sprueh- oder mikrogranulaten
JP2634285B2 (ja) * 1989-03-28 1997-07-23 積水化学工業株式会社 放射性物質取扱所の被覆材用非灰分性樹脂組成物
DE3927810A1 (de) 1989-08-23 1991-02-28 Basf Ag Riboflavingranulate
US4994458A (en) * 1990-04-30 1991-02-19 Basf Corporation Process for rotary fluid bed granulation of riboflavin
US5236920A (en) * 1990-04-30 1993-08-17 Basf Corporation Granulated riboflavin product having high flowability, high riboflavin content
DE4014262A1 (de) 1990-05-04 1991-11-07 Basf Ag Gut rieselfaehige, nichtstaubende bindemittelfreie riboflavinspruehgranulate oder -mikrogranulate aus reinem riboflavin und ein verfahren zu deren herstellung
US5000888A (en) * 1990-05-23 1991-03-19 Basf Corporation Process for spray drying riboflavin to produce a granulate product having low binder content
JP2000112883A (ja) * 1998-09-24 2000-04-21 Internatl Business Mach Corp <Ibm> 情報処理方法、情報処理装置、情報処理プログラムを格納する記憶媒体
CA2282908A1 (en) 1998-10-19 2000-04-19 F. Hoffmann-La Roche Ag Purification and crystallization process for riboflavin
US6093715A (en) * 1999-03-24 2000-07-25 Basf Aktiengesellschaft Process for producing riboflavin-containing granules

Also Published As

Publication number Publication date
ES2189711T3 (es) 2003-07-16
KR100720202B1 (ko) 2007-05-21
EP1048668A3 (en) 2001-03-28
CN1275375A (zh) 2000-12-06
EP1048668B1 (en) 2003-01-29
KR20010029668A (ko) 2001-04-06
JP2000327562A (ja) 2000-11-28
NO20002283L (no) 2000-10-31
CA2306502A1 (en) 2000-10-30
DE60001286T3 (de) 2010-10-28
AU770320B2 (en) 2004-02-19
EP1048668A2 (en) 2000-11-02
DE60001286T2 (de) 2003-11-06
JP4965013B2 (ja) 2012-07-04
ES2189711T5 (es) 2010-07-28
EP1048668B2 (en) 2010-06-09
NO20002283D0 (no) 2000-04-28
DK1048668T3 (da) 2003-05-26
NO318219B1 (no) 2005-02-21
US6723346B1 (en) 2004-04-20
AU3018900A (en) 2000-11-02
CN1198595C (zh) 2005-04-27
ATE231864T1 (de) 2003-02-15
TWI253347B (en) 2006-04-21
MXPA00004185A (es) 2002-03-08
BR0002390A (pt) 2000-10-31
DE60001286D1 (de) 2003-03-06

Similar Documents

Publication Publication Date Title
YU70901A (sh) Derivati 1,4-benzotiazepin-1,1 dioksida zamenjeni radikalima šećera, postupak za njihovu proizvodnju, lekovi koji sadrže ova jedinjenja i njihova primena
CA2334775A1 (en) Benzo(b)thiepine-1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
HUT61543A (en) Process for producing serotonin antagonist indole derivatives and pharmaceutical compositions comprising same as active ingredient
FI113651B (fi) Menetelmä terapeuttisesti käyttökelpoisten bentsimidatsoliyhdisteiden valmistamiseksi
WO1999006032A3 (es) Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion
MX9200817A (es) Derivados de piranil cianoguanidina y proceso para su preparacion.
HUT62893A (en) Process for producing substituted pyrimidine derivatives and pharmaceutical compositions comprising such compounds as active ingredient
BRPI0116967A2 (pt) derivado de pirazina ou um sal deste, composição farmacêutica, e, derivado de fluoropirazina ou um sal deste
WO2001014379A3 (en) A novel crystalline form of disodium n-[4-[2-(2-amino-4,7-dihydro-4-oxo-3h-pyrrolo[2,3-d]-pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid salt and processes therefor
ID25698A (id) Proses pembuatan granul semprot yang mengandung riboflavin
SE8901464D0 (sv) Pyridonkarboxylsyraderivat och salter daerav, foerfarande foer deras framstaellning samt antibakteriella medel innehaallande dessa
EP0994108A4 (en) METHOD FOR PRODUCING 2-HYDROXYBENZAMIDE DERIVATIVES
NO20016389L (no) Fremgangsmåte for fremstilling av substituerte cyklopentanderivater og nye krystallinske strukturer derav
DE60104697D1 (de) Sulfonamid-derivate
ES2147749T3 (es) Procedimiento para la preparacion de derivados de ciano-metoxiiminometilo.
DE3882895D1 (de) Imid-derivate, ihre herstellung und verwendung.
HUT55397A (en) Process for producing mevalonic acid derivatives comprising thienopyridine ring and pharmaceutical compositions containing such active ingredient
WO1994019343A3 (en) Novel use as anti-inflammatory agents for bis-heterocyclic compounds and pharmaceutical compositions thereof
WO1999062888A8 (en) Aza-heterocyclic compounds used to treat neurological disorders and hair loss
EP0302967A3 (en) Quinazoline derivative, processes for its production, and cerebral dysfunction remedying agent comprising it as active ingredient
DK0717042T3 (da) Fremgangsmåde til fremstilling af 1-(4,5-dihydro-2-thiazolyl)-3-azetidin-thiol-derivater
NO912650L (no) 3-((5-methyl-2-furanyl)methyl)-n-(4-piperidinyl)-3h-imidazo(4,5-b)-pyridin-2-amin-2-hydroksy-1,2,3-propantricarboksylat, dets fremstilling og anvendelse.
EP1571144A4 (en) HYDROXYALKYLATED CYCLIC DEDIAMINE COMPOUND
NO20006073L (no) Fremgangsmåte for fremstilling av krystallinske salter av amoxycillin
EP0703232A3 (en) 2,3-dihydro-1H-isoindole derivatives, process for their preparation and their use as serotonin re-assimilation inhibitors