ID26862A - Gen-gen biosintetis untuk produksi insektisida spinosin - Google Patents

Gen-gen biosintetis untuk produksi insektisida spinosin

Info

Publication number
ID26862A
ID26862A IDW20001725A ID20001725A ID26862A ID 26862 A ID26862 A ID 26862A ID W20001725 A IDW20001725 A ID W20001725A ID 20001725 A ID20001725 A ID 20001725A ID 26862 A ID26862 A ID 26862A
Authority
ID
Indonesia
Prior art keywords
biosinetic
spinosin
genes
insecticide production
insecticide
Prior art date
Application number
IDW20001725A
Other languages
English (en)
Inventor
Richard H Baltz
Broughton M Christine
Kathryn P Crawford
Krishnamurthy Madduri
Donald J Merlo
Patti J Treadway
Jan R Turner
Clive Waldron
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Publication of ID26862A publication Critical patent/ID26862A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
IDW20001725A 1998-03-09 1999-02-16 Gen-gen biosintetis untuk produksi insektisida spinosin ID26862A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/036,987 US6143526A (en) 1998-03-09 1998-03-09 Biosynthetic genes for spinosyn insecticide production

Publications (1)

Publication Number Publication Date
ID26862A true ID26862A (id) 2001-02-15

Family

ID=21891822

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20001725A ID26862A (id) 1998-03-09 1999-02-16 Gen-gen biosintetis untuk produksi insektisida spinosin

Country Status (18)

Country Link
US (4) US6143526A (id)
EP (1) EP1062345B1 (id)
JP (1) JP2002505881A (id)
KR (1) KR100588436B1 (id)
CN (1) CN1227362C (id)
AR (1) AR014687A1 (id)
AT (1) ATE380872T1 (id)
AU (1) AU764737B2 (id)
BR (1) BR9909257B1 (id)
CA (1) CA2322449C (id)
DE (1) DE69937732T2 (id)
ES (1) ES2299240T3 (id)
ID (1) ID26862A (id)
IL (2) IL138241A0 (id)
NZ (1) NZ506624A (id)
TW (1) TWI237058B (id)
WO (1) WO1999046387A1 (id)
ZA (1) ZA991837B (id)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143526A (en) * 1998-03-09 2000-11-07 Baltz; Richard H. Biosynthetic genes for spinosyn insecticide production
AU6839300A (en) * 1999-08-27 2001-03-26 Bayer Aktiengesellschaft Nucleic acids which code for the enzyme activities of the spinosyn biosynthesis
AR033022A1 (es) 2001-03-30 2003-12-03 Dow Agrosciences Llc Genes biosinteticos para la produccion de insecticida de butenilespinosina
JP2005508622A (ja) * 2001-08-06 2005-04-07 キュービスト ファーマシューティカルズ， インコーポレイテッド ダプトマイシン生合成遺伝子クラスターに関する組成物および方法
WO2003070908A2 (en) * 2002-02-19 2003-08-28 Dow Agrosciences Llc Novel spinosyn-producing polyketide synthases
EP1477563A3 (en) * 2003-05-16 2004-11-24 Wyeth Cloning genes from streptomyces cyaneogriseus subsp.noncyanogenus for biosynthesis of antibiotics and methods of use
GB0327721D0 (en) * 2003-11-28 2003-12-31 Biotica Tech Ltd Polyketides and their synthesis
WO2010032135A2 (en) * 2008-09-22 2010-03-25 Kritikou, Christine Spinosyn antifouling compositions, methods of use thereof and articles protected from attachment of biofouling organisms
TW201041509A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
TW201041507A (en) * 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity and methods for preparing same
TW201041508A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
TW201041510A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
CA2764526A1 (en) 2009-06-24 2010-12-29 Christine Kritikou The use of spinosyns and spinosyn compositions against diseases caused by protozoans, viral infections and cancer
CN102191208A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 高产多杀菌素的基因工程菌及其制备方法
WO2011143291A1 (en) * 2010-05-11 2011-11-17 Dow Agrosciences Llc Spnk strains
EP2654757A1 (en) 2010-12-22 2013-10-30 Entarco SA The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents
AU2012211052A1 (en) 2011-01-28 2013-09-05 Amyris, Inc. Gel-encapsulated microcolony screening
US9404107B2 (en) 2011-05-03 2016-08-02 Dow Agrosciences Llc Integration of genes into the chromosome of Saccharopolyspora spinosa
EP2520653B1 (en) 2011-05-03 2017-03-29 Dow AgroSciences LLC Integration of genes into the chromosome of saccharopolyspora spinosa
US8741603B2 (en) * 2011-05-03 2014-06-03 Agrigenetics Inc. Enhancing spinosyn production with oxygen binding proteins
US20140057314A1 (en) 2011-05-13 2014-02-27 Amyris, Inc. Methods and compositions for detecting microbial production of water-immiscible compounds
WO2013009690A2 (en) * 2011-07-09 2013-01-17 The Regents Of The University Of California Leukemia stem cell targeting ligands and methods of use
US9631195B2 (en) * 2011-12-28 2017-04-25 Dow Agrosciences Llc Identification and characterization of the spinactin biosysnthesis gene cluster from spinosyn producing saccharopolyspora spinosa
BR112015002724B1 (pt) 2012-08-07 2022-02-01 Total Marketing Services Método para produzir um composto não catabólico heterólogo, e, composição de fermentação
BR112015023089A2 (pt) 2013-03-15 2017-11-21 Amyris Inc célula hospedeira, método para produzir um isoprenoide, e método para aumentar a produção de acetil-coa ou um composto derivado de acetil-coa
US10563229B2 (en) 2013-08-07 2020-02-18 Amyris, Inc. Methods for stabilizing production of acetyl-coenzyme a derived compounds
CN103740631B (zh) * 2013-12-31 2015-09-30 天津大学 能提高多杀菌素产量的基因工程菌及构建方法及应用
WO2016074221A1 (zh) * 2014-11-14 2016-05-19 浙江海正药业股份有限公司 多杀菌素异源表达菌株及其构建方法和应用
CN108474009B (zh) 2015-06-25 2022-10-04 阿迈瑞斯公司 麦芽糖依赖性降解决定子、麦芽糖响应型启动子、稳定化构建体及其在生成非分解代谢化合物中的用途
EP3344612B1 (en) 2015-09-03 2020-06-17 Agrimetis, LLC Spinosyn derivatives as insecticides
MX376448B (es) 2017-01-13 2025-03-07 Agrimetis Llc Derivados de espinosina aziridina y métodos de preparación.
WO2018226810A1 (en) * 2017-06-06 2018-12-13 Zymergen Inc. High throughput transposon mutagenesis
CN109096366B (zh) * 2017-06-21 2021-09-10 中南大学 Rgd环肽偶联亲脂性阳离子多杀菌素衍生物及其制备方法和应用
CN116334021B (zh) * 2023-03-30 2026-02-03 上海交通大学 一种多杀菌素酰基转移酶突变体及其应用
WO2025003522A1 (en) * 2023-06-30 2025-01-02 Acies Bio D.O.O Genetically modified organism and method for spinosyn production
CN118420725A (zh) * 2024-05-07 2024-08-02 武汉大学 Orf-l16基因在调控多杀菌素合成中的应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935340A (en) * 1985-06-07 1990-06-19 Eli Lilly And Company Method of isolating antibiotic biosynthetic genes
EP0463707A1 (en) * 1985-12-17 1992-01-02 Lubrizol Genetics Inc. Production of polyketide antibiotics
US5672497A (en) * 1986-03-21 1997-09-30 Eli Lilly And Company Method for increasing the antibiotic-producing ability of antibiotic-producing microorganisms
US4874748A (en) * 1986-03-24 1989-10-17 Abbott Laboratories Cloning vectors for streptomyces and use thereof in macrolide antibiotic production
US5149638A (en) * 1988-09-29 1992-09-22 Eli Lilly And Company Tylosin biosynthetic genes tylA, tylB and tylI
US5362634A (en) * 1989-10-30 1994-11-08 Dowelanco Process for producing A83543 compounds
US5252474A (en) * 1989-03-31 1993-10-12 Merck & Co., Inc. Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use
WO1993013663A1 (en) * 1992-01-17 1993-07-22 Abbott Laboratories Method of directing biosynthesis of specific polyketides
WO1993006219A1 (de) 1991-09-18 1993-04-01 Hoechst Aktiengesellschaft Sekundärmetabolit-biosynthesegene aus aktinomyceten, verfahren zu ihrer isolierung sowie ihre verwendung
US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
US5672491A (en) * 1993-09-20 1997-09-30 The Leland Stanford Junior University Recombinant production of novel polyketides
DK0725778T3 (da) * 1993-09-20 2001-12-17 Univ Leland Stanford Junior Rekombinant produktion af hidtil ukendte polyketider
US5712146A (en) * 1993-09-20 1998-01-27 The Leland Stanford Junior University Recombinant combinatorial genetic library for the production of novel polyketides
CA2197524A1 (en) * 1996-02-22 1997-08-22 Bradley Stuart Dehoff Polyketide synthase genes
US6143526A (en) * 1998-03-09 2000-11-07 Baltz; Richard H. Biosynthetic genes for spinosyn insecticide production
DE19957268A1 (de) * 1999-08-27 2001-03-08 Bayer Ag Nucleinsäuren, die für Enzymaktivitäten der Spinosyn-Biosynthese kodieren
AU6839300A (en) * 1999-08-27 2001-03-26 Bayer Aktiengesellschaft Nucleic acids which code for the enzyme activities of the spinosyn biosynthesis
AR033022A1 (es) * 2001-03-30 2003-12-03 Dow Agrosciences Llc Genes biosinteticos para la produccion de insecticida de butenilespinosina

Also Published As

Publication number Publication date
CA2322449C (en) 2013-01-15
DE69937732T2 (de) 2008-12-04
IL138241A0 (en) 2001-10-31
US6521406B1 (en) 2003-02-18
AU2680099A (en) 1999-09-27
ES2299240T3 (es) 2008-05-16
DE69937732D1 (de) 2008-01-24
BR9909257B1 (pt) 2014-01-14
AR014687A1 (es) 2001-03-28
TWI237058B (en) 2005-08-01
EP1062345B1 (en) 2007-12-12
CN1227362C (zh) 2005-11-16
KR100588436B1 (ko) 2006-06-13
US6274350B1 (en) 2001-08-14
ZA991837B (en) 2000-09-08
BR9909257A (pt) 2000-11-28
US6143526A (en) 2000-11-07
EP1062345A1 (en) 2000-12-27
KR20010041750A (ko) 2001-05-25
JP2002505881A (ja) 2002-02-26
NZ506624A (en) 2003-08-29
WO1999046387A9 (en) 2001-10-04
CN1298447A (zh) 2001-06-06
IL138241A (en) 2007-09-20
US7015001B2 (en) 2006-03-21
ATE380872T1 (de) 2007-12-15
US20040023343A1 (en) 2004-02-05
AU764737B2 (en) 2003-08-28
CA2322449A1 (en) 1999-09-16
WO1999046387A1 (en) 1999-09-16

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