ID27206A - Generasi produk-produk perbanyakan gena dari protein-protein fusi simerik melalui pemutusan endoprotease ubikuitus - Google Patents

Generasi produk-produk perbanyakan gena dari protein-protein fusi simerik melalui pemutusan endoprotease ubikuitus

Info

Publication number: ID27206A
Authority: ID; Indonesia
Prior art keywords: expression; sequence encoding; endoprotease; ubikuitus; simeric
Prior art date: 1998-05-21

Application number

IDW20002666A

Other languages

English (en)

Indonesian (id)

Inventor

J A Gaken

Farzin Farzaneh

S J Russel

Original Assignee

Cancer Res Ventures Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-05-21

Filing date

1999-05-21

Publication date

2001-03-08

1999-05-21 Application filed by Cancer Res Ventures Ltd filed Critical Cancer Res Ventures Ltd

2001-03-08 Publication of ID27206A publication Critical patent/ID27206A/id

Links

101710118538 Protease Proteins 0.000 title abstract 2
108020001507 fusion proteins Proteins 0.000 title abstract 2
102000037865 fusion proteins Human genes 0.000 title abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 4
229920001184 polypeptide Polymers 0.000 abstract 3
102000004196 processed proteins & peptides Human genes 0.000 abstract 3
108090000765 processed proteins & peptides Proteins 0.000 abstract 3
102000002067 Protein Subunits Human genes 0.000 abstract 2
108010001267 Protein Subunits Proteins 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 2
238000003776 cleavage reaction Methods 0.000 abstract 1
239000000470 constituent Substances 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
102000039446 nucleic acids Human genes 0.000 abstract 1
108020004707 nucleic acids Proteins 0.000 abstract 1
150000007523 nucleic acids Chemical class 0.000 abstract 1
230000007017 scission Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4721—Lipocortins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5406—IL-4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5425—IL-9
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5434—IL-12
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Zoology (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Physics & Mathematics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Plant Pathology (AREA)
Microbiology (AREA)
Veterinary Medicine (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Saccharide Compounds (AREA)
Sorting Of Articles (AREA)

IDW20002666A 1998-05-21 1999-05-21 Generasi produk-produk perbanyakan gena dari protein-protein fusi simerik melalui pemutusan endoprotease ubikuitus ID27206A (id)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9810999.4A GB9810999D0 (en)	1998-05-21	1998-05-21	Materials and methods relating to the expression of genes

Publications (1)

Publication Number	Publication Date
ID27206A true ID27206A (id)	2001-03-08

Family

ID=10832516

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW20002666A ID27206A (id)	1998-05-21	1999-05-21	Generasi produk-produk perbanyakan gena dari protein-protein fusi simerik melalui pemutusan endoprotease ubikuitus

Country Status (13)

Country	Link
EP (1)	EP1080206B1 (de)
JP (1)	JP2002515251A (de)
KR (1)	KR20010052383A (de)
CN (1)	CN1308679A (de)
AT (1)	ATE236259T1 (de)
AU (1)	AU753785B2 (de)
CA (1)	CA2333144A1 (de)
DE (1)	DE69906509D1 (de)
ES (1)	ES2201718T3 (de)
GB (1)	GB9810999D0 (de)
ID (1)	ID27206A (de)
NZ (1)	NZ508863A (de)
WO (1)	WO1999060135A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6586411B1 (en) *	2000-08-16	2003-07-01	Mayo Foundation For Medical Education And Research	System for monitoring the location of transgenes
AU7593001A (en)	2000-07-14	2002-01-30	Zycos Inc	Alpha-msh related compounds and methods of use
EP1369128A1 (de) *	2002-06-07	2003-12-10	Procorde GmbH	Glycoprotein VI Inhibitoren und deren therapeutische Verwendung
DE602004028007D1 (de) *	2003-05-14	2010-08-19	Bayer Pharmaceuticals Corp	Interleukin-9 antagonist-muteine und ihre pharmakologischen anwendungsverfahren
WO2005017149A1 (en) *	2003-06-03	2005-02-24	Cell Genesys, Inc.	Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site
US7485291B2 (en) *	2003-06-03	2009-02-03	Cell Genesys, Inc.	Compositions and methods for generating multiple polypeptides from a single vector using a virus derived peptide cleavage site, and uses thereof
FR2856069A1 (fr) *	2003-06-10	2004-12-17	Bionexis	Molecules de ciblage et de liberation de composes therapeutiques et leur utilisation
MX2008000985A (es)	2005-07-21	2008-04-07	Abbott Lab	Expresion de gen multiple que incluye construcciones y metodos sorf (cuadro de lectura abierta simple) con poliproteinas, pro-proteinas y proteolisis.
WO2009032954A1 (en) *	2007-09-04	2009-03-12	The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services	Deletions in domain ii of pseudomonas exotoxin a that reduce non-specific toxicity
US8715964B2 (en)	2008-05-11	2014-05-06	The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services	Expression of IL-12 family heterodimers
WO2011042874A1 (en) *	2009-10-06	2011-04-14	Ecole Polytechnique Federale De Lausanne (Epfl)	Visualization of proprotein convertase activity in living cells and tissues
WO2012031137A2 (en)	2010-09-02	2012-03-08	Mayo Foundation For Medical Education And Research	Vesicular stomatitis viruses
US9951117B2 (en)	2010-09-02	2018-04-24	Mayo Foundation For Medical Education And Research	Vesicular stomatitis viruses
EP3197911A4 (de) *	2014-09-22	2018-06-20	Intrexon Corporation	Verbesserter therapeutische kontrolle von heterodimeren und einkettigen formen von interleukin-12
WO2017062953A1 (en) *	2015-10-10	2017-04-13	Intrexon Corporation	Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12
US11492384B2 (en)	2018-09-17	2022-11-08	Gi Innovation, Inc.	Fusion protein comprising IL-2 protein and CD80 protein, and use thereof
WO2020198145A1 (en) *	2019-03-22	2020-10-01	The Johns Hopkins University	Gene delivery particles to induce tumor-derived antigen presenting cells
BR112023020209A2 (pt)	2021-04-02	2023-12-19	Krystal Biotech Inc	Genoma do vírus do herpes recombinante, vírus do herpes, composição farmacêutica, uso do vírus do herpes ou da composição farmacêutica, método para expressar, realçar, aumentar, ampliar e/ou suplementar os níveis de um polipeptídeo imunomodulatório, método para prover alívio profilático, paliativo ou terapêutico, e, método para tratar câncer
CA3235894A1 (en) *	2021-10-25	2023-05-04	Brile Chung	Compositions and methods for therapeutic delivery

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2000859A6 (es) *	1985-08-12	1988-03-16	Syntex Inc	Un metodo para producir un vector de expresion bacteriana para la expresion de proteinas de fusion
DK0485504T3 (da) *	1989-08-11	1994-04-18	Zymogenetics Inc	Fremgangsmåde til fremstilling af aktiveret protein C ved celledyrkning
WO1997012048A1 (en) *	1995-09-27	1997-04-03	Medical Research Council	Recombinant viruses incorporating a protease cleavable protein

1998
- 1998-05-21 GB GBGB9810999.4A patent/GB9810999D0/en not_active Ceased
1999
- 1999-05-21 ID IDW20002666A patent/ID27206A/id unknown
- 1999-05-21 CA CA002333144A patent/CA2333144A1/en not_active Abandoned
- 1999-05-21 DE DE69906509T patent/DE69906509D1/de not_active Expired - Lifetime
- 1999-05-21 AU AU40508/99A patent/AU753785B2/en not_active Ceased
- 1999-05-21 KR KR1020007013081A patent/KR20010052383A/ko not_active Withdrawn
- 1999-05-21 CN CN99808292A patent/CN1308679A/zh active Pending
- 1999-05-21 NZ NZ508863A patent/NZ508863A/xx unknown
- 1999-05-21 AT AT99923745T patent/ATE236259T1/de not_active IP Right Cessation
- 1999-05-21 WO PCT/GB1999/001609 patent/WO1999060135A1/en not_active Ceased
- 1999-05-21 ES ES99923745T patent/ES2201718T3/es not_active Expired - Lifetime
- 1999-05-21 EP EP99923745A patent/EP1080206B1/de not_active Expired - Lifetime
- 1999-05-21 JP JP2000549741A patent/JP2002515251A/ja active Pending

Also Published As

Publication number	Publication date
WO1999060135A8 (en)	2000-01-13
KR20010052383A (ko)	2001-06-25
ATE236259T1 (de)	2003-04-15
CN1308679A (zh)	2001-08-15
GB9810999D0 (en)	1998-07-22
ES2201718T3 (es)	2004-03-16
NZ508863A (en)	2003-03-28
EP1080206A1 (de)	2001-03-07
EP1080206B1 (de)	2003-04-02
DE69906509D1 (de)	2003-05-08
AU4050899A (en)	1999-12-06
AU753785B2 (en)	2002-10-31
JP2002515251A (ja)	2002-05-28
WO1999060135A1 (en)	1999-11-25
CA2333144A1 (en)	1999-11-25

Publication	Publication Date	Title
ID27206A (id)	2001-03-08	Generasi produk-produk perbanyakan gena dari protein-protein fusi simerik melalui pemutusan endoprotease ubikuitus
DK1218504T3 (da)	2007-11-12	GL50 molekyler og anvendelser deraf
ES2177475T1 (es)	2002-12-16	Genes de corynebacterium glutamicum que codifican proteinas de una ruta metabolica.
WO1999020766A3 (en)	1999-09-02	NOVEL MODIFIED NUCLEIC ACID SEQUENCES AND METHODS FOR INCREASING mRNA LEVELS AND PROTEIN EXPRESSION IN CELL SYSTEMS
WO2002006457A3 (en)	2002-10-17	Novel lipase genes
WO2005003315A3 (en)	2005-04-14	Compositions and methods for peptide-assisted transfection
AU6518386A (en)	1987-05-21	Novel vector comprising DNA sequences containing a part of polyhedral structural gene from Bombyx Mori nuclear polyhedrosis virus, and use of said vector to produce gene products by genetic engineering
DE60144021D1 (de)	2011-03-24	Für zellzyklusproteine kodierende nukleinsäure und deren verwendung
WO2000052164A3 (en)	2001-04-05	Potassium channel molecules and uses therefor
WO2004087886A3 (en)	2006-08-10	Modified adenoviral e1a constructs and methods of use thereof
CY1106593T1 (el)	2012-01-25	Μια κωδικευουσα ακολουθια mycobacterium tuberculosis για εκφραση ετερολογων πρωτεϊνων
WO2002002771A3 (en)	2003-01-23	Human sparc-homologous (hsparc-h1) gene and methods and uses thereof
WO2002012475A3 (en)	2003-05-15	C1q-related factor, homologous polypeptides and therapeutic uses thereof
WO2001032872A3 (en)	2002-03-21	Twik potassium channel molecules and uses therefor
WO2003020912A3 (en)	2003-08-28	Novel clark protein and nucleic acid molecules and uses therefor
SE0303093D0 (sv)	2003-11-18	Expression vector, host cell and method for producing fusion proteins
WO2003040312A3 (en)	2004-10-28	Multifunctional green fluorescent protein and uses thereof
WO2003025182A1 (fr)	2003-03-27	Adn de surexpression d'une hormone de croissance et utilisation
ATE386129T1 (de)	2008-03-15	Produktion eukaryontischer proteine und nukleinsäuremoleküle in c. elegans
ATE429446T1 (de)	2009-05-15	Recombinante igf expressionssysteme
ATE346926T1 (de)	2006-12-15	Menschliche twik-8 moleküle und ihre verwendung
WO2002070708A3 (en)	2003-12-04	Glutamate receptor modulatory proteins and nucleic acids encoding them
DK0959130T3 (da)	2003-08-04	Kloning og udtrykkelse af nyt glucoamylasegen fra Endomyces fibuliger
WO2002000709A3 (en)	2002-06-20	Cerebellin homologous polypeptides and therapeutic uses thereof
WO2002016579A3 (en)	2002-11-28	Nucleic acids, vectors, host cells, polypeptides and uses thereof