ID28953A - 4-(aminometil)-piperidina benzamida untuk mengobati gangguan gastrointestinal - Google Patents

4-(aminometil)-piperidina benzamida untuk mengobati gangguan gastrointestinal

Info

Publication number
ID28953A
ID28953A IDW00200101336A ID20011336A ID28953A ID 28953 A ID28953 A ID 28953A ID W00200101336 A IDW00200101336 A ID W00200101336A ID 20011336 A ID20011336 A ID 20011336A ID 28953 A ID28953 A ID 28953A
Authority
ID
Indonesia
Prior art keywords
aminometyl
benzamide
piperidine
gastrointestinal disorders
treat gastrointestinal
Prior art date
Application number
IDW00200101336A
Other languages
English (en)
Inventor
J P R M A Bosmans
Ann L G Meulemans
M A J De Cleyn
H J M Gijsen
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ID28953A publication Critical patent/ID28953A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IDW00200101336A 1998-12-22 1999-12-14 4-(aminometil)-piperidina benzamida untuk mengobati gangguan gastrointestinal ID28953A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98204411 1998-12-22

Publications (1)

Publication Number Publication Date
ID28953A true ID28953A (id) 2001-07-19

Family

ID=8234539

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW00200101336A ID28953A (id) 1998-12-22 1999-12-14 4-(aminometil)-piperidina benzamida untuk mengobati gangguan gastrointestinal

Country Status (34)

Country Link
US (2) US6544997B1 (id)
EP (1) EP1140915B1 (id)
JP (1) JP4615725B2 (id)
KR (1) KR100633680B1 (id)
CN (1) CN1150190C (id)
AR (1) AR024240A1 (id)
AT (1) ATE297917T1 (id)
AU (1) AU770397B2 (id)
BG (1) BG64953B1 (id)
BR (1) BR9916491A (id)
CA (1) CA2355857C (id)
CZ (1) CZ300851B6 (id)
DE (1) DE69925865T2 (id)
DK (1) DK1140915T3 (id)
EA (1) EA003608B1 (id)
EE (1) EE200100335A (id)
ES (1) ES2245131T3 (id)
HK (1) HK1039114B (id)
HR (1) HRP20010445A2 (id)
HU (1) HUP0104838A3 (id)
ID (1) ID28953A (id)
IL (1) IL143858A (id)
MY (1) MY121852A (id)
NO (1) NO321324B1 (id)
NZ (1) NZ512871A (id)
PL (1) PL197409B1 (id)
PT (1) PT1140915E (id)
SI (1) SI1140915T1 (id)
SK (1) SK285829B6 (id)
TR (1) TR200101962T2 (id)
TW (1) TW570920B (id)
UA (1) UA71591C2 (id)
WO (1) WO2000037461A1 (id)
ZA (1) ZA200105135B (id)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7485665B2 (en) * 2002-09-12 2009-02-03 Nagase Chemtex Corporation Medicinal composition
JO2478B1 (en) * 2003-06-19 2009-01-20 جانسين فارماسوتيكا ان. في. (Aminomethyl) -biperidine benzamides as 5 HT4 antagonists
US7498347B2 (en) 2003-06-19 2009-03-03 Janssen Pharmaceutica, N.V. Hydroxycarbonylphenyl substituted 4-(aminomethyl)-piperidine benzamides as 5HT4 antagonists
AU2004254190B2 (en) * 2003-06-19 2010-04-22 Janssen Pharmaceutica N.V. Heterocyclic substituted 4-(aminomethyl)-piperidine benzamides as 5HT4-antagonists
US7652040B2 (en) * 2003-06-19 2010-01-26 Janssen Pharmaceutica N.V. Aminosulfonyl substituted 4-(aminomethyl)-piperidine benzamides as 5HT4-antagonists
AU2004254193B2 (en) * 2003-06-19 2010-02-18 Janssen Pharmaceutica N.V. 5ht4-antagonistic 4-(aminomethyl)-piperidine benzamides
ATE539077T1 (de) * 2003-09-03 2012-01-15 Pfizer Benzimidazolonverbindungen mit agonistischer wirkung am 5-ht4 rezeptor
CA2545092C (en) * 2003-11-24 2010-08-17 Pfizer Inc. Quinolonecarboxylic acid compounds having 5-ht4 receptor agonistic activity
TW200533348A (en) * 2004-02-18 2005-10-16 Theravance Inc Indazole-carboxamide compounds as 5-ht4 receptor agonists
US8309575B2 (en) 2004-04-07 2012-11-13 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
TWI351282B (en) 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
US7728006B2 (en) * 2004-04-07 2010-06-01 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
BRPI0512046A (pt) 2004-06-15 2008-02-06 Pfizer derivados de ácido benzimidazolona carboxìlico
US20060035890A1 (en) * 2004-08-10 2006-02-16 Amit Banerjee Compounds and methods for the treatment of ubiquitin conjugating disorders
ES2332808T3 (es) * 2004-11-05 2010-02-12 Theravance, Inc. Compuestos agonistas del receptor 5-ht4.
EP1807423B1 (en) * 2004-11-05 2009-05-20 Theravance, Inc. Quinolinone-carboxamide compounds
MX2007007818A (es) * 2004-12-22 2007-09-11 Theravance Inc Compuestos de indazol-carboxamida.
ES2523851T3 (es) * 2005-03-02 2014-12-02 Theravance Biopharma R&D Ip, Llc Compuestos de quinolinona como agonistas de los receptores 5-HT4
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
US8377968B2 (en) * 2008-06-02 2013-02-19 Zalicus Pharmaceuticals, Ltd. N-piperidinyl acetamide derivatives as calcium channel blockers
EP2961403A4 (en) 2013-03-01 2016-11-30 Zalicus Pharmaceuticals Ltd HETEROCYCLIC INHIBITORS OF SODIUM CHANNEL
CA3001857A1 (en) * 2015-10-14 2017-04-20 Aquinnah Pharmaceuticals, Inc. Compounds, compositions and methods of use against stress granules
KR20220066252A (ko) 2019-07-11 2022-05-24 프락시스 프리시젼 메디신즈, 인크. T형 칼슘 채널 조절제의 제형 및 이의 사용 방법

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ225152A (en) * 1987-07-17 1990-04-26 Janssen Pharmaceutica Nv Heterocyclically substituted piperidinyl benzamides as pharmaceuticals
CA1317940C (en) * 1987-09-25 1993-05-18 Georges H. P. Van Daele Substituted n-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides
US5374637A (en) 1989-03-22 1994-12-20 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
AU2435092A (en) 1991-08-20 1993-03-16 Smithkline Beecham Plc 5-ht4 receptor antagonists
FI941178L (fi) * 1991-09-12 1994-03-11 Smithkline Beecham Plc 5-HT4-reseptoriantagonisteja
ES2121988T3 (es) * 1992-01-23 1998-12-16 Toray Industries Derivado de morfinano y uso medicinal.
NZ246915A (en) * 1992-02-06 1996-05-28 Smithkline Beecham Plc Benzopyran, benzothiopyran and benzofuran derivatives, preparation and pharmaceutical compositions thereof
WO1994008994A1 (en) 1992-10-13 1994-04-28 Smithkline Beecham Plc Heterocyclic -esters or -amides used as 5-ht4 receptor antagonists
GB9219163D0 (en) 1992-09-10 1992-10-28 Smithkline Beecham Plc Pharmaceuticals
MX9306311A (es) 1992-10-13 1994-04-29 Smithkline Beecham Plc Compuestos antagonistas del receptor de 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que los contienen
WO1994010174A1 (en) * 1992-11-05 1994-05-11 Smithkline Beecham Plc Piperidine derivatives as 5-ht4 receptor antagonists
GB9301660D0 (en) * 1993-01-28 1993-03-17 Smithkline Beecham Plc Pharmaceuticals
GB9312348D0 (en) 1993-06-16 1993-07-28 Smithkline Beecham Plc Pharmaceuticals
ES2103675B1 (es) * 1995-01-10 1998-07-01 Almirall Lab Nuevas piperidinas sustituidas.
IT1275903B1 (it) 1995-03-14 1997-10-24 Boehringer Ingelheim Italia Esteri e ammidi della 1,4-piperidina disostituita
GB9507882D0 (en) * 1995-04-18 1995-05-31 Pharmacia Spa Substituted dihydrobenzofuran derivatives as 5-ht4 agonists
CA2237582C (en) * 1996-02-15 2009-04-14 Janssen Pharmaceutica N.V. Use of 5ht4 receptor antagonists for overcoming gastrointestinal effects of serotonin reuptake inhibitors
TW445263B (en) * 1996-02-29 2001-07-11 Janssen Pharmaceutica Nv Novel esters of 1,4-disubstituted piperidine derivatives
TW548103B (en) * 1997-07-11 2003-08-21 Janssen Pharmaceutica Nv Bicyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives
CA2340952C (en) * 1998-09-10 2009-12-08 F. Hoffmann-La Roche Ag Dihydrobenzodioxine carboxamide and ketone derivatives as 5-ht4 receptor antagonists
DE10217868A1 (de) * 2002-04-22 2003-10-30 Jomed N V Ballon-Katheter

Also Published As

Publication number Publication date
ES2245131T3 (es) 2005-12-16
NO321324B1 (no) 2006-04-24
CN1150190C (zh) 2004-05-19
ZA200105135B (en) 2002-06-21
EA200100710A1 (ru) 2001-12-24
PL197409B1 (pl) 2008-03-31
WO2000037461A1 (en) 2000-06-29
HK1039114A1 (en) 2002-04-12
HUP0104838A2 (hu) 2002-07-29
SK285829B6 (sk) 2007-09-06
US7205410B2 (en) 2007-04-17
HUP0104838A3 (en) 2003-05-28
AR024240A1 (es) 2002-09-25
JP2002533337A (ja) 2002-10-08
EP1140915A1 (en) 2001-10-10
DK1140915T3 (da) 2005-10-10
MY121852A (en) 2006-02-28
HK1039114B (en) 2005-08-19
CZ20012117A3 (cs) 2001-10-17
NO20012858L (no) 2001-06-08
KR100633680B1 (ko) 2006-10-11
KR20010080293A (ko) 2001-08-22
CA2355857A1 (en) 2000-06-29
SK8592001A3 (en) 2002-02-05
BG105571A (en) 2002-01-31
EA003608B1 (ru) 2003-06-26
BG64953B1 (bg) 2006-10-31
CN1331690A (zh) 2002-01-16
UA71591C2 (en) 2004-12-15
CA2355857C (en) 2008-10-28
EE200100335A (et) 2002-08-15
DE69925865D1 (de) 2005-07-21
EP1140915B1 (en) 2005-06-15
TW570920B (en) 2004-01-11
BR9916491A (pt) 2001-09-04
ATE297917T1 (de) 2005-07-15
IL143858A (en) 2005-03-20
TR200101962T2 (tr) 2002-04-22
AU2432800A (en) 2000-07-12
NO20012858D0 (no) 2001-06-08
DE69925865T2 (de) 2006-05-11
JP4615725B2 (ja) 2011-01-19
US6544997B1 (en) 2003-04-08
AU770397B2 (en) 2004-02-19
PL348417A1 (en) 2002-05-20
US20030181456A1 (en) 2003-09-25
IL143858A0 (en) 2002-04-21
NZ512871A (en) 2002-11-26
PT1140915E (pt) 2005-11-30
HRP20010445A2 (en) 2002-06-30
SI1140915T1 (sl) 2005-12-31
CZ300851B6 (cs) 2009-08-26

Similar Documents

Publication Publication Date Title
ID28953A (id) 4-(aminometil)-piperidina benzamida untuk mengobati gangguan gastrointestinal
ID24481A (id) Gastrokinetik monosiklik benzamida dari derivat-3-atau-tersubstitusi 4-(aminometil)-piperidin
DE60121614D1 (de) Nachweis von neurologischen funktionsstörungen
EP1496894A4 (en) ANGIOGENESIS INHIBITORS
DE60118908D1 (de) Behandlung von mineralischen stoffen
ATE411332T1 (de) 3'-prodrugs von 2'-deoxy-beta-l-nukleosiden
DE60300021D1 (de) (S)-4-Amino-5-Chloro-2-Methoxy-N-[1-[1-(2-Tetrahydrofuryl-Carbonyl)-4-Piperidinylmethyl]-4-Piperidinyl]benzamid zur Behandlung von Magen-Darmbewegungskrankheiten
DE59912795D1 (de) Substituierte Benzamide und ihre Verwendung als Immunmodulatoren
PL357674A1 (pl) Kompozycje i sposoby leczenia zaburzeń związanychz hiperlipidemią
EP1379236A4 (en) TREATMENT OF TICS, TREMOR AND RELATED DISORDER
NO20006547D0 (no) Salter av paroxetine
NO20032156L (no) Behandling av angstforstyrrelser
DE60019145D1 (de) Verwendung von carbonylaminoderivaten gegen zentralnervensystem-störungen
ATE243197T1 (de) Kristallformen von osanetant
ATE317261T1 (de) Verwendung von mirtazapin zur behandlung von schlafstörungen
DE60026931D1 (de) Ausrichtung von Ausdrucken
NO20010390D0 (no) Behandling av angstsykdommer
NO20014953L (no) Anvendelse av osanetant for fremstilling av medikamenter anvendt for å behandle sinnsstemningslidelser
ATE221882T1 (de) Neue substituierte n-methyl-n-(4-(4-(1h- benzimidazol-2-yl-amino)-piperidin-1-yl)- 2(aryl)butyl)benzamide zur behandlung von allergischen krankheiten
NO993372D0 (no) Substituerte 4-(6-fluor-(1H)-indol-3-yl)-1,2,3,6-tetrahydropyridin for behandling av CNS-forstyrrelser
DE60336549D1 (de) Hepatoprotektor aktivität von 2'-p-hydroxybenzoylmussaenosidsäure
NO20004583D0 (no) Krystallinsk form av paroxetine
NO20005351D0 (no) Paroksetin 10-kamfersulfonat for behandling av CNS lidelser
NO20005286L (no) Behandling av generelle angstforstyrrelser med paroxetin
DK82798A (da) Treatment of GABA-uptake related disorders