ID29095A - Antagonis mglur5 untuk pengobatan rasa sakit dan kegelisahan - Google Patents

Antagonis mglur5 untuk pengobatan rasa sakit dan kegelisahan

Info

Publication number: ID29095A
Authority: ID; Indonesia
Prior art keywords: pain; treatment; antagonists; mglur5 antagonists; mglur
Prior art date: 1998-10-02

Application number

IDW20010730A

Other languages

English (en)

Inventor

Hans Allgeier

Nicholas D Cosford

Peter Josef Flor

Fabrizio Gasparini

Conrad Gentsch

Stephen D Hess

Edwin C Johnson

Rainer Kuhn

Mark Tricklebank

Laszlo Urban

Mark A Varney

Gonul Velicelebi

Katharine Walker

Original Assignee

Novartis Ag Cs

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-10-02

Filing date

1999-09-30

Publication date

2001-07-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26314451&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ID29095(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-10-02 Priority claimed from GBGB9821503.1A external-priority patent/GB9821503D0/en

1999-09-30 Application filed by Novartis Ag Cs filed Critical Novartis Ag Cs

2001-07-26 Publication of ID29095A publication Critical patent/ID29095A/id

Links

239000005557 antagonist Substances 0.000 title abstract 3
101150087728 Grm5 gene Proteins 0.000 title 1
102100038357 Metabotropic glutamate receptor 5 Human genes 0.000 title 1
208000019901 Anxiety disease Diseases 0.000 abstract 1
102000012777 Metabotropic Glutamate 5 Receptor Human genes 0.000 abstract 1
108010065028 Metabotropic Glutamate 5 Receptor Proteins 0.000 abstract 1
102000016193 Metabotropic glutamate receptors Human genes 0.000 abstract 1
108010010914 Metabotropic glutamate receptors Proteins 0.000 abstract 1
230000000202 analgesic effect Effects 0.000 abstract 1
230000036506 anxiety Effects 0.000 abstract 1
230000003993 interaction Effects 0.000 abstract 1
229940124807 mGLUR antagonist Drugs 0.000 abstract 1
230000002093 peripheral effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyridine Compounds (AREA)

IDW20010730A 1998-10-02 1999-09-30 Antagonis mglur5 untuk pengobatan rasa sakit dan kegelisahan ID29095A (id)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9821503.1A GB9821503D0 (en)	1998-10-02	1998-10-02	Organic compounds
US22081398A	1998-12-23	1998-12-23

Publications (1)

Publication Number	Publication Date
ID29095A true ID29095A (id)	2001-07-26

Family

ID=26314451

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW20010730A ID29095A (id)	1998-10-02	1999-09-30	Antagonis mglur5 untuk pengobatan rasa sakit dan kegelisahan

Country Status (21)

Country	Link
EP (1)	EP1117403B1 (id)
JP (1)	JP2002526408A (id)
KR (1)	KR20010088832A (id)
CN (1)	CN1187048C (id)
AT (1)	ATE255894T1 (id)
AU (1)	AU765644B2 (id)
BR (1)	BR9914215A (id)
CA (1)	CA2345137A1 (id)
DE (1)	DE69913548T2 (id)
DK (1)	DK1117403T3 (id)
ES (1)	ES2213389T3 (id)
HU (1)	HUP0200553A3 (id)
ID (1)	ID29095A (id)
IL (2)	IL142047A0 (id)
NO (1)	NO20011440L (id)
NZ (1)	NZ510743A (id)
PL (1)	PL202906B1 (id)
PT (1)	PT1117403E (id)
RU (1)	RU2232017C2 (id)
SK (1)	SK4382001A3 (id)
WO (1)	WO2000020001A1 (id)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0005700D0 (en) *	2000-03-09	2000-05-03	Glaxo Group Ltd	Therapy
KR100545906B1 (ko) *	2000-12-22	2006-01-26	에프. 호프만-라 로슈 아게	ｍＧｌｕＲ 1 길항물질로서의 테트라하이드로-(벤조 또는티에노)-아제핀-피라진 및 트리아진 유도체
GB0128996D0 (en)	2001-12-04	2002-01-23	Novartis Ag	Organic compounds
SE0303419D0 (sv) *	2003-12-17	2003-12-17	Astrazeneca Ab	New use 11
SE0303418D0 (sv) *	2003-12-17	2003-12-17	Astrazeneca Ab	New use 1
FR2883180B1 (fr) *	2005-03-18	2007-05-25	Pierre Fabre Medicament Sa	Utilisation de l'acetyl-leucine pour la preparation d'un medicament destine au traitement de troubles de l'equilibre
GB0525068D0 (en)	2005-12-08	2006-01-18	Novartis Ag	Organic compounds
DE102005062985A1 (de) *	2005-12-28	2007-07-05	Grünenthal GmbH	Substituierte bis(hetero)aromatische N-Ethylpropiolamide und ihre Verwendung zur Herstellung von Arzneimitteln
HUE032743T2 (en)	2006-11-22	2017-10-30	Clinical Res Ass Llc	A method for treating Down syndrome, fragilis X syndrome and autism
US8349852B2 (en)	2009-01-13	2013-01-08	Novartis Ag	Quinazolinone derivatives useful as vanilloid antagonists
US8586581B2 (en) *	2009-12-17	2013-11-19	Hoffmann-La Roche Inc	Ethynyl compounds useful for treatment of CNS disorders
CN102762572A (zh)	2010-02-01	2012-10-31	诺瓦提斯公司	作为CRF-1受体拮抗剂的吡唑并[5,1b]*唑衍生物
AR080056A1 (es)	2010-02-01	2012-03-07	Novartis Ag	Derivados de ciclohexil-amida como antagonistas de los receptores de crf
JP5748777B2 (ja)	2010-02-02	2015-07-15	ノバルティスアーゲー	Ｃｒｆ受容体アンタゴニストとしてのシクロヘキシルアミド誘導体
WO2011109398A2 (en)	2010-03-02	2011-09-09	President And Fellows Of Harvard College	Methods and compositions for treatment of angelman syndrome and autism spectrum disorders
WO2011150380A1 (en)	2010-05-28	2011-12-01	Xenoport, Inc.	Methods of treatment of fragile x syndrome, down's syndrome, autism and related disorders
US20120016021A1 (en)	2010-07-15	2012-01-19	Xenoport, Inc.	Methods of treating fragile x syndrome, down's syndrome, autism and related disorders
WO2012054724A1 (en)	2010-10-21	2012-04-26	Massachusetts Institute Of Technology	Methods of treating seizure disorders
US8546416B2 (en)	2011-05-27	2013-10-01	Novartis Ag	3-spirocyclic piperidine derivatives as ghrelin receptor agonists
EP2557183A1 (de)	2011-08-12	2013-02-13	Siemens Aktiengesellschaft	Verfahren zum Betrieb einer Konti-Glühe für die Verarbeitung eines Walzguts
CA2867043A1 (en)	2012-05-03	2013-11-07	Novartis Ag	L-malate salt of 2,7-diaza-spiro[4.5]dec-7-yle derivatives and crystalline forms thereof as ghrelin receptor agonists
JP6603334B2 (ja)	2015-06-03	2019-11-06	エフ．ホフマン−ラロシュアーゲー	エチニル誘導体
KR20200035035A (ko)	2017-07-31	2020-04-01	노파르티스 아게	코카인 사용 감소 또는 코카인 사용 재발 예방에 있어서 마보글루란트의 용도
EP3459939A1 (en)	2017-09-26	2019-03-27	Pragma Therapeutics	Novel heterocyclic compounds as modulators of mglur7
KR102027368B1 (ko) *	2018-05-29	2019-10-01	서울대학교산학협력단	통증의 강도를 측정하는 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE68907095T2 (de) *	1988-03-21	1994-01-05	Boehringer Ingelheim Pharma	Verbindungen zur Verhinderung der Biosynthese von der Lipoxygenase abgeleiteten Metaboliten der Arachidonsäure.
TW544448B (en) *	1997-07-11	2003-08-01	Novartis Ag	Pyridine derivatives

1999
- 1999-09-30 JP JP2000573360A patent/JP2002526408A/ja active Pending
- 1999-09-30 BR BR9914215-5A patent/BR9914215A/pt not_active Application Discontinuation
- 1999-09-30 DK DK99948905T patent/DK1117403T3/da active
- 1999-09-30 EP EP99948905A patent/EP1117403B1/en not_active Revoked
- 1999-09-30 HU HU0200553A patent/HUP0200553A3/hu unknown
- 1999-09-30 CA CA002345137A patent/CA2345137A1/en not_active Abandoned
- 1999-09-30 PT PT99948905T patent/PT1117403E/pt unknown
- 1999-09-30 PL PL346876A patent/PL202906B1/pl not_active IP Right Cessation
- 1999-09-30 AU AU61984/99A patent/AU765644B2/en not_active Ceased
- 1999-09-30 IL IL14204799A patent/IL142047A0/xx active IP Right Grant
- 1999-09-30 CN CNB998117110A patent/CN1187048C/zh not_active Expired - Fee Related
- 1999-09-30 ES ES99948905T patent/ES2213389T3/es not_active Expired - Lifetime
- 1999-09-30 ID IDW20010730A patent/ID29095A/id unknown
- 1999-09-30 WO PCT/EP1999/007239 patent/WO2000020001A1/en not_active Ceased
- 1999-09-30 RU RU2001111868/14A patent/RU2232017C2/ru not_active IP Right Cessation
- 1999-09-30 AT AT99948905T patent/ATE255894T1/de active
- 1999-09-30 SK SK438-2001A patent/SK4382001A3/sk unknown
- 1999-09-30 KR KR1020017004152A patent/KR20010088832A/ko not_active Ceased
- 1999-09-30 DE DE69913548T patent/DE69913548T2/de not_active Revoked
- 1999-09-30 NZ NZ510743A patent/NZ510743A/en unknown
2001
- 2001-03-15 IL IL142047A patent/IL142047A/en not_active IP Right Cessation
- 2001-03-21 NO NO20011440A patent/NO20011440L/no unknown

Also Published As

Publication number	Publication date
CN1187048C (zh)	2005-02-02
PT1117403E (pt)	2004-04-30
AU6198499A (en)	2000-04-26
NO20011440L (no)	2001-05-15
IL142047A (en)	2007-09-20
PL202906B1 (pl)	2009-08-31
CA2345137A1 (en)	2000-04-13
DE69913548T2 (de)	2004-09-23
SK4382001A3 (en)	2001-08-06
EP1117403A1 (en)	2001-07-25
BR9914215A (pt)	2001-07-03
PL346876A1 (en)	2002-03-11
HUP0200553A3 (en)	2002-11-28
IL142047A0 (en)	2002-03-10
HUP0200553A2 (hu)	2002-07-29
DK1117403T3 (da)	2004-04-13
DE69913548D1 (de)	2004-01-22
RU2232017C2 (ru)	2004-07-10
NO20011440D0 (no)	2001-03-21
ES2213389T3 (es)	2004-08-16
EP1117403B1 (en)	2003-12-10
NZ510743A (en)	2003-10-31
JP2002526408A (ja)	2002-08-20
WO2000020001A1 (en)	2000-04-13
CN1321087A (zh)	2001-11-07
KR20010088832A (ko)	2001-09-28
ATE255894T1 (de)	2003-12-15
AU765644B2 (en)	2003-09-25

Publication	Publication Date	Title
ID29095A (id)	2001-07-26	Antagonis mglur5 untuk pengobatan rasa sakit dan kegelisahan
ATE359076T1 (de)	2007-05-15	Mittel gegen juckreiz
TR200100922T2 (tr)	2001-09-21	Aktif maddelerin akciğerler yolu ile tatbik edilmesi.
CY1108610T1 (el)	2014-04-09	Πεπτιδια της il-2 και παραγωγα αυτων και χρηση αυτων ως θεραπευτικοι παραγοντες
ATE284388T1 (de)	2004-12-15	Cyclpentanoindole, mischungen derartige verbindungen enthaltend und behandlungsmethoden
ID29950A (id)	2001-10-25	Bahan-bahan karbon amorf gabungan, pembuatan dan penggunaannya
EA200100780A1 (ru)	2001-12-24	Антагонисты tweak и рецептора tweak и их использование для лечения иммунологических заболеваний
ID30393A (id)	2001-11-29	Senyawa tienopirimidina, pembuatan dan penggunaannya
DE60118544D1 (de)	2006-05-18	Methoden und zusammensetzungen zur modulation der aktivität der alpha-adrenergen rezeptoren
CY1111946T1 (el)	2015-11-04	To (1s, 5s) -3-(5,6-διχλωρο-3-πυριδινυλο)-3, 6-διαζαδικυ-κλο[3.2.0]επτανιο ειναι ενας αποτελεσματiκος αναλγητικος παραγοντας
PT951282E (pt)	2008-06-09	Prevenção e tratamento de doenças esqueléticas com agonistas e2 de protaglandinas selectivos do subtipo de receptores ep2
DE60108857D1 (de)	2005-03-17	Methoden und zusammensetzungen zur modulierung der aktivität von alpha-adrenergen rezeptoren
EE200300559A (et)	2004-02-16	Osteopontiini kasutamine neuroloogiliste haigusteraviks ja/või vältimiseks
EA199900912A1 (ru)	2000-04-24	Фармацевтические средства
ATE371454T1 (de)	2007-09-15	Antagonisten der prostaglandin ep2 und/oder ep4 rezeptoren zur behandlung von menorrhagie
DE50114605D1 (de)	2009-02-05	No-thien-2-yl-essigsaure-derivate und ihre verwendung zur behandlung von migraine bzw. schmerz
DE60016047D1 (de)	2004-12-23	Dihydrobenzopyrane, dihydrobenzothiopyrane und tetrahydrochinoline zur behandlung cox-2-abhängiger krankheiten
DE602004016752D1 (de)	2008-11-06	Kombination enthaltend substanzen mit npy-rezeptor affinität und substanzen mit 5-ht6-rezeptor affinität
NO991460L (no)	1999-03-25	Anvendelse av 1-hydroksy-2-pyridoner til behandling av seborÚisk dermatitt
FR2820036B1 (fr)	2005-12-09	Utilisation d'un isothiocyanate, d'un thiocyanate ou de leur melange en tant que depigmentant
NO20005548D0 (no)	2000-11-03	Mykobakterieinhibitorer
EA200001050A1 (ru)	2001-04-23	Малеат пароксетина
DK1054671T3 (da)	2003-02-24	Ny anvendelse til smertebehandling
DE69936779D1 (de)	2007-09-20	Verwendung von ngali nussöl zur behandlung/linderung der arthritisschmerzen und anderer ähnlichen störungen
FR2841897B1 (fr)	2004-12-10	Procede de preparation d'un ciment apatitique, ledit ciment ainsi que son utilisation pour pieger les polluants