ID29578A - Turunan-turunan indeno-, nafto- dan benzosikloheptadihidrotiazol serta pembuatan dan penggunaannya sebagai obat-obatan anorektik - Google Patents

Turunan-turunan indeno-, nafto- dan benzosikloheptadihidrotiazol serta pembuatan dan penggunaannya sebagai obat-obatan anorektik

Info

Publication number
ID29578A
ID29578A IDW20010719A ID20010719A ID29578A ID 29578 A ID29578 A ID 29578A ID W20010719 A IDW20010719 A ID W20010719A ID 20010719 A ID20010719 A ID 20010719A ID 29578 A ID29578 A ID 29578A
Authority
ID
Indonesia
Prior art keywords
benzosicloheptihihidrotiazol
nafto
indeno
derives
manufacturing
Prior art date
Application number
IDW20010719A
Other languages
English (en)
Indonesian (id)
Inventor
Gerhard Dr Jaehne
Heiner Dr Glombik
Karl Dr Geisen
Martin Dr Bickel
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of ID29578A publication Critical patent/ID29578A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IDW20010719A 1998-09-29 1999-09-16 Turunan-turunan indeno-, nafto- dan benzosikloheptadihidrotiazol serta pembuatan dan penggunaannya sebagai obat-obatan anorektik ID29578A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19844547A DE19844547C2 (de) 1998-09-29 1998-09-29 Polycyclische Dihydrothiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
ID29578A true ID29578A (id) 2001-09-06

Family

ID=7882588

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20010719A ID29578A (id) 1998-09-29 1999-09-16 Turunan-turunan indeno-, nafto- dan benzosikloheptadihidrotiazol serta pembuatan dan penggunaannya sebagai obat-obatan anorektik

Country Status (25)

Country Link
US (2) US6090833A (tr)
EP (1) EP1119557B1 (tr)
JP (1) JP3542078B2 (tr)
KR (1) KR20010079952A (tr)
CN (1) CN1143852C (tr)
AR (1) AR020662A1 (tr)
AT (1) ATE255569T1 (tr)
AU (1) AU755158B2 (tr)
BR (1) BR9915014A (tr)
CA (1) CA2345359A1 (tr)
DE (2) DE19844547C2 (tr)
DK (1) DK1119557T3 (tr)
ES (1) ES2212673T3 (tr)
HK (1) HK1040080B (tr)
HU (1) HUP0103504A3 (tr)
ID (1) ID29578A (tr)
IL (1) IL142096A0 (tr)
NO (1) NO318388B1 (tr)
NZ (1) NZ510399A (tr)
PL (1) PL347072A1 (tr)
PT (1) PT1119557E (tr)
RU (1) RU2217427C2 (tr)
TR (1) TR200100868T2 (tr)
WO (1) WO2000018749A1 (tr)
ZA (1) ZA200102446B (tr)

Families Citing this family (32)

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DE19908539A1 (de) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Polycyclische 2-Amino-Dihydrothiazolsysteme, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
BR0015322A (pt) * 1999-11-05 2002-07-09 Aventis Pharma Gmbh Derivados de indeno-, nafto- e benzociclohepta-dihidrotiazol, sua preparação e seu emprego como medicamentos anoréticos
HRP20020688A2 (en) * 2000-02-23 2004-12-31 Aventis Pharma Gmbh 8,8a-dihydro-indeno[1,2-d]thiazole derivatives, substituted in position 8a, a method for their production and their use as medicaments, e.g. anorectic agents
DE10008274A1 (de) * 2000-02-23 2001-08-30 Aventis Pharma Gmbh Substituierte 8,8a-Dihydro-3aH-indeno[1,2-d]thiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE50100558D1 (de) * 2000-02-26 2003-10-02 Aventis Pharma Gmbh 8,8a-dihydro-indeno 1,2-d]thiazol-derivate, die in 2-stellung einen substituenten mit einer sulfonamidstruktur oder sulfonstruktur tragen; verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE10142665B4 (de) * 2001-08-31 2004-05-06 Aventis Pharma Deutschland Gmbh C2-Disubstituierte Indan-1-one und ihre Derivate
DE10142663B4 (de) 2001-08-31 2004-08-19 Aventis Pharma Deutschland Gmbh C2-Disubstituierte Indan-1-ol-Systeme
DE10142722A1 (de) 2001-08-31 2003-03-27 Aventis Pharma Deutschland GmbH, 65929 Frankfurt C2-substituierte Indan-1-one und ihre Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US20080125403A1 (en) 2004-04-02 2008-05-29 Merck & Co., Inc. Method of Treating Men with Metabolic and Anthropometric Disorders
UA100497C2 (ru) 2006-09-07 2013-01-10 Никомед Гмбх Комбинированное лечение сахарного диабета
KR101560844B1 (ko) 2007-06-04 2015-10-15 벤-구리온 유니버시티 오브 더 네게브 리서치 앤드 디벨럽먼트 어쏘러티 트라이-아릴계 화합물 및 이를 포함하는 조성물
MX2009013293A (es) 2007-06-04 2010-02-15 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2810951B1 (en) 2008-06-04 2017-03-15 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2348857B1 (en) 2008-10-22 2016-02-24 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
JP5557845B2 (ja) 2008-10-31 2014-07-23 メルク・シャープ・アンド・ドーム・コーポレーション 糖尿病用剤として有用な新規環状ベンゾイミダゾール誘導体
AU2011218830B2 (en) 2010-02-25 2014-07-24 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
MX348131B (es) 2011-02-25 2017-05-26 Merck Sharp & Dohme Novedosos derivados de azabencimidazol ciclico utiles como agentes antidiabeticos.
CA3100941C (en) 2011-03-01 2024-03-05 Synergy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
WO2014022528A1 (en) 2012-08-02 2014-02-06 Merck Sharp & Dohme Corp. Antidiabetic tricyclic compounds
WO2014130608A1 (en) 2013-02-22 2014-08-28 Merck Sharp & Dohme Corp. Antidiabetic bicyclic compounds
WO2014139388A1 (en) 2013-03-14 2014-09-18 Merck Sharp & Dohme Corp. Novel indole derivatives useful as anti-diabetic agents
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
EA201592263A1 (ru) 2013-06-05 2016-05-31 Синерджи Фармасьютикалз, Инк. Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования
WO2015051496A1 (en) 2013-10-08 2015-04-16 Merck Sharp & Dohme Corp. Antidiabetic tricyclic compounds
EA201690938A1 (ru) 2013-11-05 2016-11-30 Бен-Гурион Юниверсити Оф Дзе Негев Рисерч Энд Дивелопмент Оторити Соединения для лечения диабета и осложнений, возникающих из-за этого заболевания
US11072602B2 (en) 2016-12-06 2021-07-27 Merck Sharp & Dohme Corp. Antidiabetic heterocyclic compounds
EP3558298B1 (en) 2016-12-20 2026-03-11 Merck Sharp & Dohme LLC Antidiabetic spirochroman compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2942003A (en) * 1957-06-06 1960-06-21 Gen Aniline & Film Corp Process for preparing naphtho [1, 2-d]-thiazoles
DE2640358A1 (de) * 1976-09-08 1978-03-16 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
CA1292226C (en) * 1986-01-16 1991-11-19 Terumi Hachiya Indenothiazole derivative and process for preparing the same
JPH0514068A (ja) * 1991-07-03 1993-01-22 Shimada Phys & Chem Ind Co Ltd 並列増幅部切換型高周波低雑音増幅装置
JP3197602B2 (ja) * 1992-02-17 2001-08-13 久光製薬株式会社 チアゾール類縁化合物及び皮膚外用剤
MX9603998A (es) * 1994-03-11 1997-12-31 Yamanouchi Pharma Co Ltd Agonista receptor de 5-ht3, derivado de tiazol novedoso e intermediario del mismo.
GB9517381D0 (en) * 1995-08-24 1995-10-25 Pharmacia Spa Aryl and heteroaryl piperazine derivatives
TW416953B (en) * 1996-09-25 2001-01-01 Takeda Chemical Industries Ltd Tricyclic compounds for eliciting a prostaglandin I2 receptor agonistic effect, their production and use

Also Published As

Publication number Publication date
HUP0103504A2 (hu) 2002-07-29
PL347072A1 (en) 2002-03-11
JP2002525363A (ja) 2002-08-13
JP3542078B2 (ja) 2004-07-14
US6291486B1 (en) 2001-09-18
NO20011503L (no) 2001-03-23
US6090833A (en) 2000-07-18
CN1143852C (zh) 2004-03-31
ATE255569T1 (de) 2003-12-15
DE19844547C2 (de) 2002-11-07
NO20011503D0 (no) 2001-03-23
ES2212673T3 (es) 2004-07-16
DK1119557T3 (da) 2004-04-13
DE19844547A1 (de) 2000-03-30
AU5978799A (en) 2000-04-17
BR9915014A (pt) 2001-08-07
KR20010079952A (ko) 2001-08-22
TR200100868T2 (tr) 2001-09-21
DE59907961D1 (de) 2004-01-15
CA2345359A1 (en) 2000-04-06
HK1040080A1 (en) 2002-05-24
AR020662A1 (es) 2002-05-22
CN1320120A (zh) 2001-10-31
NZ510399A (en) 2003-10-31
ZA200102446B (en) 2001-09-28
HK1040080B (zh) 2004-08-20
EP1119557A1 (de) 2001-08-01
HUP0103504A3 (en) 2002-10-28
EP1119557B1 (de) 2003-12-03
PT1119557E (pt) 2004-04-30
RU2217427C2 (ru) 2003-11-27
NO318388B1 (no) 2005-03-14
IL142096A0 (en) 2002-03-10
WO2000018749A1 (de) 2000-04-06
AU755158B2 (en) 2002-12-05

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