ID30183A - Turunan-turunan peptida berat molekul rendah sebagai penghambat-penghambat interaksi laminin/nidogen - Google Patents

Turunan-turunan peptida berat molekul rendah sebagai penghambat-penghambat interaksi laminin/nidogen

Info

Publication number
ID30183A
ID30183A IDW00200101881A ID20011881A ID30183A ID 30183 A ID30183 A ID 30183A ID W00200101881 A IDW00200101881 A ID W00200101881A ID 20011881 A ID20011881 A ID 20011881A ID 30183 A ID30183 A ID 30183A
Authority
ID
Indonesia
Prior art keywords
laminin
nidogen
low
interactions
weight peptides
Prior art date
Application number
IDW00200101881A
Other languages
English (en)
Inventor
Hans U Dr Stilz
Martin Dr Gerl
Gary A Dr Flynn
Magda Stankova
Robert A Binnie
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of ID30183A publication Critical patent/ID30183A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
IDW00200101881A 1999-03-01 2000-02-19 Turunan-turunan peptida berat molekul rendah sebagai penghambat-penghambat interaksi laminin/nidogen ID30183A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99103869A EP1070727A1 (en) 1999-03-01 1999-03-01 Low molecular weight peptide derivatives as inhibitors of the laminin/nidogen interaction

Publications (1)

Publication Number Publication Date
ID30183A true ID30183A (id) 2001-11-08

Family

ID=8237658

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW00200101881A ID30183A (id) 1999-03-01 2000-02-19 Turunan-turunan peptida berat molekul rendah sebagai penghambat-penghambat interaksi laminin/nidogen

Country Status (21)

Country Link
US (1) US6365572B1 (id)
EP (4) EP1070727A1 (id)
JP (1) JP4542272B2 (id)
CN (2) CN1237075C (id)
AT (2) ATE477271T1 (id)
AU (1) AU779779B2 (id)
BR (1) BR0008647A (id)
CA (1) CA2363958C (id)
CY (1) CY1106967T1 (id)
CZ (1) CZ300736B6 (id)
DE (2) DE60044832D1 (id)
DK (1) DK1157040T3 (id)
ES (1) ES2288844T3 (id)
HU (1) HU228993B1 (id)
ID (1) ID30183A (id)
PL (2) PL202887B1 (id)
PT (1) PT1157040E (id)
RU (2) RU2262509C2 (id)
TR (2) TR200102560T2 (id)
WO (1) WO2000052051A1 (id)
ZA (1) ZA200106972B (id)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1070727A1 (en) * 1999-03-01 2001-01-24 Aventis Pharma Deutschland GmbH Low molecular weight peptide derivatives as inhibitors of the laminin/nidogen interaction
US20080241835A1 (en) * 1999-11-01 2008-10-02 Genentech, Inc. Differentially expressed genes involved in angiogenesis, the polypeptides encoded thereby, and methods of using the same
AU784338B2 (en) * 1999-11-01 2006-03-16 Curagen Corporation Differentially expressed genes involved in angiogenesis, the polypeptides encoded thereby, and methods of using the same
WO2004093892A2 (en) 2003-04-16 2004-11-04 Genentech, Inc. Stanniocalcin-1, variant or antagonists thereof for selective modulation of vascularization
FR2947452B1 (fr) 2009-07-01 2012-04-20 Fabre Pierre Dermo Cosmetique L-serine et/ou l-asparagine et/ou l-valine pour prevenir et/ou au traiter des reactions inflammatoires de la peau.
RU2622018C1 (ru) * 2016-06-16 2017-06-08 федеральное государственное автономное образовательное учреждение высшего образования "Российский университет дружбы народов" (РУДН) Быстро растворяющаяся трансбуккальная плёнка для лечения депрессивных расстройств, тревоги и расстройств адаптации
EP3551608A1 (en) * 2016-12-09 2019-10-16 Celtaxsys Inc. Pendant amines and derivatives as inhibitors of leukotriene a4 hydrolase

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8821785D0 (en) * 1988-09-16 1988-10-19 Nycomed As Peptide compounds
RU2145233C1 (ru) * 1990-07-02 2000-02-10 Дзе Аризона Борд оф Риджентс Неупорядоченная библиотека пептидов, способ ее получения и способ идентификации пептида, синтезированного твердофазным синтезом
US5493008A (en) * 1994-08-15 1996-02-20 The University Of Virginia Patent Foundation Two non-contiguous regions contribute to nidogen binding to a single EGF-like motif of the laminin γ1 chain
DE19622489A1 (de) * 1996-06-05 1997-12-11 Hoechst Ag Salze des 3-(2-(4-(4-(Amino-imino-methyl)-phenyl)-4- methyl-2,5-dioxo-imidazolidin-1-yl)-acetylamino)-3- phenyl-propionsäure-ethylesters
DE19701607A1 (de) 1997-01-17 1998-07-23 Hoechst Ag Anitkörper, die an die Nidogen-Bindungsdomäne des Laminins binden, deren Herstellung und Verwendung
EP1070727A1 (en) * 1999-03-01 2001-01-24 Aventis Pharma Deutschland GmbH Low molecular weight peptide derivatives as inhibitors of the laminin/nidogen interaction

Also Published As

Publication number Publication date
EP2239270A2 (en) 2010-10-13
DK1157040T3 (da) 2007-12-03
RU2262509C2 (ru) 2005-10-20
DE60036087D1 (de) 2007-10-04
TR200102560T2 (tr) 2002-01-21
CZ20013063A3 (cs) 2001-11-14
EP1157040B1 (en) 2007-08-22
PL202887B1 (pl) 2009-08-31
EP1070727A1 (en) 2001-01-24
AU3157700A (en) 2000-09-21
PT1157040E (pt) 2007-09-25
CA2363958C (en) 2012-04-17
DE60044832D1 (de) 2010-09-23
CN1237075C (zh) 2006-01-18
JP2002539092A (ja) 2002-11-19
CN1775801A (zh) 2006-05-24
US6365572B1 (en) 2002-04-02
EP2239270A3 (en) 2011-01-12
AU779779B2 (en) 2005-02-10
DE60036087T2 (de) 2008-05-15
EP1157040A1 (en) 2001-11-28
ES2288844T3 (es) 2008-02-01
ATE477271T1 (de) 2010-08-15
PL351483A1 (en) 2003-04-22
HK1087126A1 (zh) 2006-10-06
HUP0200192A3 (en) 2002-09-30
RU2005114905A (ru) 2006-11-20
CY1106967T1 (el) 2012-01-25
EP1845106A1 (en) 2007-10-17
ATE370969T1 (de) 2007-09-15
HU228993B1 (en) 2013-07-29
WO2000052051A1 (en) 2000-09-08
CA2363958A1 (en) 2000-09-08
EP1845106B1 (en) 2010-08-11
CZ300736B6 (cs) 2009-07-29
ZA200106972B (en) 2002-08-07
CN1342167A (zh) 2002-03-27
PL208356B1 (pl) 2011-04-29
HK1042499A1 (en) 2002-08-16
HUP0200192A2 (en) 2002-06-29
BR0008647A (pt) 2002-01-22
CN100441594C (zh) 2008-12-10
RU2380371C2 (ru) 2010-01-27
JP4542272B2 (ja) 2010-09-08
TR200800782T2 (tr) 2008-08-21

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