ID30237A - KOMBINASI PENGHAMBAT-PENGHAMBAT FBPase DAN PEMEKA-PEMEKA INSULIN UNTUK PENGOBATAN DIABETES - Google Patents

KOMBINASI PENGHAMBAT-PENGHAMBAT FBPase DAN PEMEKA-PEMEKA INSULIN UNTUK PENGOBATAN DIABETES

Info

Publication number: ID30237A
Authority: ID; Indonesia
Prior art keywords: insulin; fbpase; obstacles; plants; combination
Prior art date: 1998-12-24

Application number

IDW00200101612A

Other languages

English (en)

Inventor

Mark D Erion

Paul Van Poelje

Original Assignee

Metabasis Therapeutics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-24

Filing date

1999-12-22

Publication date

2001-11-15

1999-12-22 Application filed by Metabasis Therapeutics Inc filed Critical Metabasis Therapeutics Inc

2001-11-15 Publication of ID30237A publication Critical patent/ID30237A/id

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 4
102000004877 Insulin Human genes 0.000 title abstract 2
108090001061 Insulin Proteins 0.000 title abstract 2
206010012601 diabetes mellitus Diseases 0.000 title abstract 2
229940125396 insulin Drugs 0.000 title abstract 2
101710099475 3'-phosphoadenosine 5'-phosphate phosphatase Proteins 0.000 abstract 1
101710196411 Fructose-1,6-bisphosphatase Proteins 0.000 abstract 1
101710186733 Fructose-1,6-bisphosphatase, chloroplastic Proteins 0.000 abstract 1
101710109119 Fructose-1,6-bisphosphatase, cytosolic Proteins 0.000 abstract 1
101710198902 Fructose-1,6-bisphosphate aldolase/phosphatase Proteins 0.000 abstract 1
206010022489 Insulin Resistance Diseases 0.000 abstract 1
229940122355 Insulin sensitizer Drugs 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
230000002641 glycemic effect Effects 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
230000003914 insulin secretion Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Hematology (AREA)
Endocrinology (AREA)
Obesity (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
Cardiology (AREA)
Child & Adolescent Psychology (AREA)
Reproductive Health (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Plant Substances (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)

IDW00200101612A 1998-12-24 1999-12-22 KOMBINASI PENGHAMBAT-PENGHAMBAT FBPase DAN PEMEKA-PEMEKA INSULIN UNTUK PENGOBATAN DIABETES ID30237A (id)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US11471898P	1998-12-24	1998-12-24

Publications (1)

Publication Number	Publication Date
ID30237A true ID30237A (id)	2001-11-15

Family

ID=22357016

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW00200101612A ID30237A (id)	1998-12-24	1999-12-22	KOMBINASI PENGHAMBAT-PENGHAMBAT FBPase DAN PEMEKA-PEMEKA INSULIN UNTUK PENGOBATAN DIABETES

Country Status (25)

Country	Link
EP (1)	EP1143955B1 (id)
JP (1)	JP2003515523A (id)
KR (3)	KR100689943B1 (id)
CN (3)	CN101164618A (id)
AT (1)	ATE300288T1 (id)
AU (1)	AU771039B2 (id)
BR (1)	BR9917005A (id)
CA (1)	CA2354053A1 (id)
CZ (1)	CZ20012353A3 (id)
DE (1)	DE69926400T2 (id)
DK (1)	DK1143955T3 (id)
ES (1)	ES2246586T3 (id)
HK (1)	HK1046863B (id)
HU (1)	HUP0402506A3 (id)
ID (1)	ID30237A (id)
IL (2)	IL143569A0 (id)
MX (1)	MXPA01006511A (id)
NO (1)	NO20013115L (id)
NZ (1)	NZ512219A (id)
PL (1)	PL352756A1 (id)
PT (1)	PT1143955E (id)
RU (2)	RU2227749C2 (id)
SK (1)	SK9172001A3 (id)
WO (1)	WO2000038666A2 (id)
ZA (1)	ZA200105016B (id)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6284748B1 (en)	1997-03-07	2001-09-04	Metabasis Therapeutics, Inc.	Purine inhibitors of fructose 1,6-bisphosphatase
US6312662B1 (en)	1998-03-06	2001-11-06	Metabasis Therapeutics, Inc.	Prodrugs phosphorus-containing compounds
DE69910045T2 (de)	1998-09-09	2004-04-22	Metabasis Therapeutics Inc., San Diego	Neue heteroaromatische fructose 1,6-bisphosphatase inhibitoren
MXPA02006156A (es) *	1999-12-22	2003-09-22	Metabasis Therapeutics Inc	Nuevos profarmacos de bisamidato fosfonato.
AU2001245532B2 (en)	2000-03-08	2005-08-11	Metabasis Therapeutics, Inc.	Novel aryl fructose-1,6-bisphosphatase inhibitors
US7563774B2 (en)	2000-06-29	2009-07-21	Metabasis Therapeutics, Inc.	Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes
PL365779A1 (en) *	2000-07-06	2005-01-10	Metabasis Therapeutics, Inc.	A combination of fbpase inhibitors and antidiabetic agents useful for the treatment of diabetes
EP1340749A4 (en)	2000-11-17	2007-09-05	Takeda Pharmaceutical	ISOXAZOLE DERIVATIVES
AU2003235501A1 (en)	2002-05-13	2003-11-11	Metabasis Therapeutics, Inc.	PMEA and PMPA cyclic producing synthesis
US7214668B2 (en)	2002-05-13	2007-05-08	Metabasis Therapeutics, Inc.	Phosphonic acid based prodrugs of PMEA and its analogues
JP4719465B2 (ja) *	2002-09-04	2011-07-06	ディーエスエムアイピーアセッツビー．ブイ．	インスリン感受性増強剤およびペプチド画分を含む栄養補給用および治療用組成物
UA80991C2 (en)	2002-10-07	2007-11-26		Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes
CA2515726C (en) *	2003-02-11	2012-07-10	Vernalis (Cambridge) Limited	Isoxazole compounds
BRPI0418082B8 (pt)	2003-12-26	2021-05-25	Kyowa Hakko Kirin Co Ltd	derivados de tiazol úteis como antagonistas de receptor de adenosina a2a
JP2008510018A (ja) *	2004-08-18	2008-04-03	メタバシス・セラピューティクス・インコーポレイテッド	フルクトース−１，６−ビスホスファターゼの新規チアゾール阻害物質
US20070259928A1 (en) *	2004-12-13	2007-11-08	Taishi Yoshida	Medicinal Composition for Treating Diabetes
EP1825854A1 (en) *	2004-12-15	2007-08-29	Daiichi Sankyo Company, Limited	MEDICINAL COMPOSITION CONTAINING FBPase INHIBITOR
TW200722088A (en) *	2005-05-27	2007-06-16	Sankyo Co	Diabetes remedy
US20100280023A1 (en)	2005-06-23	2010-11-04	Kyowa Hakko Kogyo Co., Ltd.	Thiazole derivatives
WO2008057930A2 (en)	2006-11-02	2008-05-15	Aestus Therapeutics, Inc.	Methods of treating neuropathic pain with retinoic acid receptor agonists
CN103665043B (zh)	2012-08-30	2017-11-10	江苏豪森药业集团有限公司	一种替诺福韦前药及其在医药上的应用
US9631825B2 (en)	2012-12-18	2017-04-25	Nortek Air Solutions, Llc	Air filter assembly
AU2015217221A1 (en)	2014-02-13	2016-08-11	Ligand Pharmaceuticals, Inc.	Prodrug compounds and their uses
JP2017520545A (ja)	2014-07-02	2017-07-27	リガンド・ファーマシューティカルズ・インコーポレイテッド	プロドラッグ化合物およびそれらの使用
CN105481896A (zh) *	2015-12-03	2016-04-13	浙江大学	一种地马格列的制备方法
CN113416739B (zh) *	2021-06-24	2022-04-19	黑龙江八一农垦大学	鲁氏酵母菌基因在提高微生物产hdmf的产量中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4968790A (en) *	1988-08-12	1990-11-06	American Cyanamid Company	Antidiabetic phosphates
JPH03157377A (ja) *	1988-11-18	1991-07-05	Takeda Chem Ind Ltd	チオ尿素誘導体及びａｇｅ生成阻害剤
JPH03504728A (ja) *	1989-01-24	1991-10-17	ジェンシア・ファーマシュウティカルズ，インコーポレイテッド	Ａｉｃａリボシドの放出および血液グルコースの低減のための化合物および方法
TWI238064B (en) *	1995-06-20	2005-08-21	Takeda Chemical Industries Ltd	A pharmaceutical composition for prophylaxis and treatment of diabetes
US5859037A (en) *	1997-02-19	1999-01-12	Warner-Lambert Company	Sulfonylurea-glitazone combinations for diabetes
US6284748B1 (en) *	1997-03-07	2001-09-04	Metabasis Therapeutics, Inc.	Purine inhibitors of fructose 1,6-bisphosphatase
AU6691798A (en) *	1997-03-07	1998-09-22	Metabasis Therapeutics, Inc.	Novel indole and azaindole inhibitors of fructose-1,6-bisphosphatase
DE69819311T2 (de) *	1997-03-07	2004-07-29	Metabasis Therapeutics Inc., San Diego	Neue benzimidazol inhibitoren der fructose-1,6-bisphosphatase

1999
- 1999-12-22 ID IDW00200101612A patent/ID30237A/id unknown
- 1999-12-22 CN CNA2007101628889A patent/CN101164618A/zh active Pending
- 1999-12-22 MX MXPA01006511A patent/MXPA01006511A/es active IP Right Grant
- 1999-12-22 HU HU0402506A patent/HUP0402506A3/hu active IP Right Revival
- 1999-12-22 DE DE69926400T patent/DE69926400T2/de not_active Expired - Lifetime
- 1999-12-22 JP JP2000590620A patent/JP2003515523A/ja active Pending
- 1999-12-22 CZ CZ20012353A patent/CZ20012353A3/cs unknown
- 1999-12-22 RU RU2001120726/15A patent/RU2227749C2/ru not_active IP Right Cessation
- 1999-12-22 WO PCT/US1999/030713 patent/WO2000038666A2/en not_active Ceased
- 1999-12-22 DK DK99964313T patent/DK1143955T3/da active
- 1999-12-22 AU AU20583/00A patent/AU771039B2/en not_active Ceased
- 1999-12-22 NZ NZ512219A patent/NZ512219A/xx not_active IP Right Cessation
- 1999-12-22 ES ES99964313T patent/ES2246586T3/es not_active Expired - Lifetime
- 1999-12-22 KR KR1020017008102A patent/KR100689943B1/ko not_active Expired - Fee Related
- 1999-12-22 BR BR9917005-1A patent/BR9917005A/pt not_active Application Discontinuation
- 1999-12-22 CN CNA2005100806150A patent/CN1714866A/zh active Pending
- 1999-12-22 KR KR1020067022095A patent/KR20060114724A/ko not_active Ceased
- 1999-12-22 IL IL14356999A patent/IL143569A0/xx active IP Right Grant
- 1999-12-22 EP EP99964313A patent/EP1143955B1/en not_active Expired - Lifetime
- 1999-12-22 SK SK917-2001A patent/SK9172001A3/sk unknown
- 1999-12-22 PL PL99352756A patent/PL352756A1/xx not_active Application Discontinuation
- 1999-12-22 HK HK02108475.5A patent/HK1046863B/zh not_active IP Right Cessation
- 1999-12-22 KR KR1020077008649A patent/KR20070046210A/ko not_active Ceased
- 1999-12-22 CA CA002354053A patent/CA2354053A1/en not_active Abandoned
- 1999-12-22 CN CNB998163562A patent/CN100352505C/zh not_active Expired - Fee Related
- 1999-12-22 PT PT99964313T patent/PT1143955E/pt unknown
- 1999-12-22 AT AT99964313T patent/ATE300288T1/de active
2001
- 2001-06-05 IL IL143569A patent/IL143569A/en not_active IP Right Cessation
- 2001-06-19 ZA ZA200105016A patent/ZA200105016B/en unknown
- 2001-06-21 NO NO20013115A patent/NO20013115L/no not_active Application Discontinuation
2003
- 2003-10-31 RU RU2003132054/14A patent/RU2003132054A/ru not_active Application Discontinuation

Also Published As

Publication number	Publication date
IL143569A0 (en)	2002-04-21
DK1143955T3 (da)	2005-11-14
WO2000038666A2 (en)	2000-07-06
KR100689943B1 (ko)	2007-03-08
HUP0402506A2 (hu)	2005-04-28
EP1143955A3 (en)	2002-08-28
DE69926400T2 (de)	2006-05-24
NO20013115L (no)	2001-08-24
BR9917005A (pt)	2002-04-02
ZA200105016B (en)	2002-09-19
HK1046863A1 (zh)	2003-01-30
WO2000038666A3 (en)	2001-11-29
KR20010099942A (ko)	2001-11-09
CN100352505C (zh)	2007-12-05
HK1046863B (zh)	2008-07-25
PL352756A1 (en)	2003-09-08
EP1143955B1 (en)	2005-07-27
AU2058300A (en)	2000-07-31
CN1714866A (zh)	2006-01-04
CZ20012353A3 (cs)	2001-12-12
ATE300288T1 (de)	2005-08-15
CN1350466A (zh)	2002-05-22
NZ512219A (en)	2004-12-24
KR20070046210A (ko)	2007-05-02
KR20060114724A (ko)	2006-11-07
JP2003515523A (ja)	2003-05-07
HUP0402506A3 (en)	2007-05-29
PT1143955E (pt)	2005-11-30
IL143569A (en)	2006-06-11
EP1143955A2 (en)	2001-10-17
AU771039B2 (en)	2004-03-11
RU2003132054A (ru)	2005-04-20
SK9172001A3 (en)	2002-04-04
ES2246586T3 (es)	2006-02-16
MXPA01006511A (es)	2004-03-19
NO20013115D0 (no)	2001-06-21
CA2354053A1 (en)	2000-07-06
RU2227749C2 (ru)	2004-04-27
DE69926400D1 (de)	2005-09-01
CN101164618A (zh)	2008-04-23

Publication	Publication Date	Title
ID30237A (id)	2001-11-15	KOMBINASI PENGHAMBAT-PENGHAMBAT FBPase DAN PEMEKA-PEMEKA INSULIN UNTUK PENGOBATAN DIABETES
BR0308928A (pt)	2005-01-04	Uso de toxina botulìnica para o tratamento de doenças cardiovasculares, bem como composição para uso em um procedimento cardiovascular
DK1373215T3 (da)	2006-11-13	Gelanamycinderivater egnet til behandling af cancer
TW200502385A (en)	2005-01-16	Modulation of forkhead box o1a expression
DE60118723D1 (de)	2006-05-24	Verwendung von azetogenischen hydrogenotrophischen stämmen zur vorbeugung und behandlung von verdauungskrankheiten
MXPA02012272A (es)	2003-04-25	Compuestos heterociclicos que son inhibidores de la enzima dipeptidilpeptidasa-iv.
DE69525151D1 (de)	2002-03-14	Methoden zur krankheitsbehandlung unter verwendung von sertoli-zellen und allotransplantat oder xenotransplantat
ATE531688T1 (de)	2011-11-15	Verbindungen zur modulation des rage-rezeptors
EP1505990A4 (en)	2008-02-20	METHOD FOR THE TREATMENT OF HEPATITIS
ATE415962T1 (de)	2008-12-15	Verwendung von asiatsäure oder asiaticosid zur behandlung von krebs
WO2002078639A3 (en)	2003-04-10	A method of treating proliferative diseases using eg5 inhibitors
EP1098642A4 (en)	2004-08-18	METHODS OF TREATING MODULATED CONDITIONS WITH LACTOSYLCERAMIDE
AU8647101A (en)	2002-03-13	Compounds having activity as inhibitors of cytochrome p450rai
MXPA05000765A (es)	2005-10-19	Compuestos de 5-ariltetrazola, composiciones de los mismos y usos para los mismos.
DK1237562T3 (da)	2005-03-14	Fremgangsmåde til fremstilling af mikania-ekstrakter, som indeholder mikanolid og dihydromikanolid, og anvendelse i behandlingen af prolifererende sygdomme
ATE402694T1 (de)	2008-08-15	Verwendung von 1-phenyl-3-dimethylamino-propan- verbindungen zur therapie der harninkontinenz
AU3308099A (en)	1999-09-15	Method for the treatment of pain, including chronic and female specific pain
PL1865990T3 (pl)	2011-04-29	Sposób leczenia cukrzycy typu 2
DE60034110D1 (de)	2007-05-10	Verwendung von 4-aminopyridin zur behandlung von peripheren neuropathien
DE60128084D1 (de)	2007-06-06	Verwendung von inaktives cln2 proenzym zur behandlung von lincl
ATE526992T1 (de)	2011-10-15	Methode zum schutz therapeutischer zusammensetzungen von hostvermittelter inaktivierung
AP9801416A0 (en)	1998-12-31	Method Of treating a plant disease.
ATE306278T1 (de)	2005-10-15	Behandlung von knochenleiden mit adrenomedullin
DE69928814D1 (de)	2006-01-12	Verwendung von tgf-beta inhibitoren zur behandlung von cerebralen krankheiten
SE9702993D0 (sv)	1997-08-18	Anti-mikrobial komposition