ID30485A - Kombinasi obat yang terdiri dari ( e ) 7 [ 4 ( 4 fluorofenil ) 6 isopropil 2 [ metil (metilsulfonil) - amino ] pirimidin 5 il ] (3r,5s) 3,5 dihidroksihept-6- asam enoik dan suatu penghambat, bahat penginduksi atau bahan dari p450 isoenzim 3a4 - Google Patents

Kombinasi obat yang terdiri dari ( e ) 7 [ 4 ( 4 fluorofenil ) 6 isopropil 2 [ metil (metilsulfonil) - amino ] pirimidin 5 il ] (3r,5s) 3,5 dihidroksihept-6- asam enoik dan suatu penghambat, bahat penginduksi atau bahan dari p450 isoenzim 3a4

Info

Publication number
ID30485A
ID30485A IDW00200101892A ID20011892A ID30485A ID 30485 A ID30485 A ID 30485A ID W00200101892 A IDW00200101892 A ID W00200101892A ID 20011892 A ID20011892 A ID 20011892A ID 30485 A ID30485 A ID 30485A
Authority
ID
Indonesia
Prior art keywords
pyrimidine
amino
metylsulfonyl
methodsulfonyl
isoenzim
Prior art date
Application number
IDW00200101892A
Other languages
English (en)
Indonesian (id)
Inventor
Ali Raza
John Stuart Pears
Howard Gerard Hutchinson
Dennis Schneck
Takahiko Baba
Akira Touchi
Yoshitaka Yamaguchi
Original Assignee
Astrazeneca Ab
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27269637&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ID30485(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9902593.4A external-priority patent/GB9902593D0/en
Priority claimed from GBGB9921063.5A external-priority patent/GB9921063D0/en
Priority claimed from GBGB9921064.3A external-priority patent/GB9921064D0/en
Application filed by Astrazeneca Ab, Shionogi & Co filed Critical Astrazeneca Ab
Publication of ID30485A publication Critical patent/ID30485A/id

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IDW00200101892A 1999-02-06 2000-02-01 Kombinasi obat yang terdiri dari ( e ) 7 [ 4 ( 4 fluorofenil ) 6 isopropil 2 [ metil (metilsulfonil) - amino ] pirimidin 5 il ] (3r,5s) 3,5 dihidroksihept-6- asam enoik dan suatu penghambat, bahat penginduksi atau bahan dari p450 isoenzim 3a4 ID30485A (id)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9902593.4A GB9902593D0 (en) 1999-02-06 1999-02-06 Drug combinations
GBGB9921063.5A GB9921063D0 (en) 1999-09-08 1999-09-08 Therapy
GBGB9921064.3A GB9921064D0 (en) 1999-09-08 1999-09-08 Drug combination

Publications (1)

Publication Number Publication Date
ID30485A true ID30485A (id) 2001-12-13

Family

ID=27269637

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW00200101892A ID30485A (id) 1999-02-06 2000-02-01 Kombinasi obat yang terdiri dari ( e ) 7 [ 4 ( 4 fluorofenil ) 6 isopropil 2 [ metil (metilsulfonil) - amino ] pirimidin 5 il ] (3r,5s) 3,5 dihidroksihept-6- asam enoik dan suatu penghambat, bahat penginduksi atau bahan dari p450 isoenzim 3a4

Country Status (28)

Country Link
US (3) US6982157B1 (pl)
EP (1) EP1185274B1 (pl)
JP (2) JP2002536331A (pl)
KR (2) KR20010101790A (pl)
CN (1) CN1165310C (pl)
AR (1) AR029333A1 (pl)
AT (1) ATE282415T1 (pl)
AU (1) AU767304B2 (pl)
BR (1) BR0007999A (pl)
CA (1) CA2358632C (pl)
CZ (1) CZ301296B6 (pl)
DE (1) DE60015965T2 (pl)
EE (1) EE04929B1 (pl)
EG (1) EG23858A (pl)
ES (1) ES2232418T3 (pl)
GB (1) GB0000710D0 (pl)
ID (1) ID30485A (pl)
IL (1) IL144715A0 (pl)
IS (1) IS2337B (pl)
MX (1) MXPA01007905A (pl)
MY (1) MY130606A (pl)
NO (1) NO320745B1 (pl)
NZ (1) NZ512982A (pl)
PL (1) PL198034B1 (pl)
PT (1) PT1185274E (pl)
TR (1) TR200102228T2 (pl)
TW (1) TWI282738B (pl)
WO (1) WO2000045817A1 (pl)

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Publication number Priority date Publication date Assignee Title
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
DE19944803A1 (de) * 1999-09-20 2001-03-29 Bayer Ag Kombination von Dihydropyridinverbindungen und HMG-CoA-Reduktase-Inhibitoren und ihre Verwendung in Arzneimitteln
GB0001621D0 (en) * 2000-01-26 2000-03-15 Astrazeneca Ab Pharmaceutical compositions
GB0003305D0 (en) 2000-02-15 2000-04-05 Zeneca Ltd Pyrimidine derivatives
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
HU230253B1 (hu) 2001-01-26 2015-11-30 Merck Sharp & Dohme Corp Peroxiszóma proliferátor-aktivált receptor (PPAR) aktivátor(ok) és szterin-abszorpció inhibitor(ok) kombinációi és alkalmazásuk vaszkuláris indikációk kezelésére
DK1355644T3 (da) 2001-01-26 2006-10-23 Schering Corp Anvendelse af substituerede azetidinonforbindelser til behandling af sitosterolæmi
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
JP2005504091A (ja) 2001-09-21 2005-02-10 シェーリング コーポレイション ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置
WO2004043457A1 (en) 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
CA2517571C (en) 2003-03-07 2011-07-05 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP4589919B2 (ja) 2003-03-07 2010-12-01 シェーリング コーポレイション 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
JP2006519869A (ja) 2003-03-07 2006-08-31 シェーリング コーポレイション 置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
GB0322552D0 (en) 2003-09-26 2003-10-29 Astrazeneca Uk Ltd Therapeutic treatment
US9173847B2 (en) 2003-10-10 2015-11-03 Veloxis Pharmaceuticals A/S Tablet comprising a fibrate
CA2540984C (en) 2003-10-10 2011-02-08 Lifecycle Pharma A/S A solid dosage form comprising a fibrate
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
JP2008509154A (ja) 2004-08-06 2008-03-27 トランスフオーム・フアーマシユーチカルズ・インコーポレーテツド 新規なスタチン薬剤組成物および関連治療方法
WO2007005941A2 (en) 2005-07-05 2007-01-11 President And Fellows Of Harvard College Liver targeted conjugates
WO2007071357A2 (en) 2005-12-20 2007-06-28 Lek Pharmaceuticals D.D. Pharmaceutical composition comprising (e) -7- [4- (4-fluorophenyl) -6-isopropyl-2- [methyl (methylsulfonyl) amino] pyrimidin-5 -yl- (3r, 5s) -3, 5-dihydr0xyhept-6-en0ic acid
US20080109252A1 (en) * 2006-11-08 2008-05-08 Lafountain Andrea Predicting patient compliance with medical treatment
US20120130202A1 (en) * 2010-11-24 2012-05-24 Fujitsu Limited Diagnosis and Monitoring of Musculoskeletal Pathologies
WO2019241519A1 (en) * 2018-06-14 2019-12-19 Astrazeneca Uk Limited Methods for lowering blood pressure with a dihydropyridine-type calcium channel blocker pharmaceutical composition
BR112022001514A2 (pt) * 2019-07-31 2022-03-22 Intas Pharmaceuticals Ltd Composição farmacêutica multicamada e processo para a preparação de uma composição farmacêutica
WO2024223797A1 (en) 2023-04-28 2024-10-31 Institut National de la Santé et de la Recherche Médicale Use of cyp3a4 inhibitors for the treatment of hepatitis d virus (hdv) infections

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2627696B1 (fr) * 1988-02-26 1991-09-13 Fournier Innovation Synergie Nouvelle forme galenique du fenofibrate
JP2648897B2 (ja) * 1991-07-01 1997-09-03 塩野義製薬株式会社 ピリミジン誘導体
ATE114286T1 (de) * 1991-07-02 1994-12-15 Benckiser Gmbh Joh A Zusammenfaltbare vorratsflasche.
JP3852621B2 (ja) * 1992-01-21 2006-12-06 あすか製薬株式会社 血管内皮細胞機能改善剤
FR2730231B1 (fr) * 1995-02-02 1997-04-04 Fournier Sca Lab Association de fenofibrate et de vitamine e, utilisation en therapeutique
EP1027045A4 (en) * 1997-10-31 2004-12-08 Arch Dev Corp METHODS AND COMPILATIONS FOR REGULATING S-ALPHA REDUCTASE ACTIVITY

Also Published As

Publication number Publication date
PT1185274E (pt) 2005-03-31
US20060040969A1 (en) 2006-02-23
WO2000045817A1 (en) 2000-08-10
IL144715A0 (en) 2002-06-30
US20090042911A1 (en) 2009-02-12
CZ301296B6 (cs) 2010-01-06
EE04929B1 (et) 2007-12-17
US6982157B1 (en) 2006-01-03
JP2002536331A (ja) 2002-10-29
NZ512982A (en) 2003-08-29
NO20013811D0 (no) 2001-08-03
IS2337B (is) 2008-02-15
EP1185274A1 (en) 2002-03-13
TWI282738B (en) 2007-06-21
BR0007999A (pt) 2001-11-06
ATE282415T1 (de) 2004-12-15
DE60015965T2 (de) 2006-01-05
ES2232418T3 (es) 2005-06-01
NO320745B1 (no) 2006-01-23
AU2121800A (en) 2000-08-25
CN1338936A (zh) 2002-03-06
KR20010101790A (ko) 2001-11-14
NO20013811L (no) 2001-10-02
IS6009A (is) 2001-07-17
EG23858A (en) 2007-11-18
AU767304B2 (en) 2003-11-06
EE200100406A (et) 2002-10-15
GB0000710D0 (en) 2000-03-08
PL198034B1 (pl) 2008-05-30
PL364780A1 (pl) 2004-12-13
CN1165310C (zh) 2004-09-08
DE60015965D1 (de) 2004-12-23
KR20060117381A (ko) 2006-11-16
CA2358632C (en) 2008-10-28
MY130606A (en) 2007-07-31
AR029333A1 (es) 2003-06-25
TR200102228T2 (tr) 2002-03-21
CA2358632A1 (en) 2000-08-10
CZ20012844A3 (cs) 2001-11-14
JP2007277267A (ja) 2007-10-25
EP1185274B1 (en) 2004-11-17
MXPA01007905A (es) 2003-06-04
HK1041817A1 (en) 2002-07-26

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