IE41143B1 - Thienyl and thietyl compounds - Google Patents

Thienyl and thietyl compounds

Info

Publication number: IE41143B1
Authority: IE; Ireland
Prior art keywords: thienyl; thietyl; compounds; ureas; urea
Prior art date: 1974-04-17

Application number

IE865/75A

Other languages

English (en)

Other versions

IE41143L (en

Original Assignee

Du Pont

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-04-17

Filing date

1975-04-17

Publication date

1979-10-24

1975-04-17 Application filed by Du Pont filed Critical Du Pont

1975-10-17 Publication of IE41143L publication Critical patent/IE41143L/xx

1979-10-24 Publication of IE41143B1 publication Critical patent/IE41143B1/xx

Links

150000001875 compounds Chemical class 0.000 title abstract 2
125000001544 thienyl group Chemical group 0.000 title abstract 2
235000013877 carbamide Nutrition 0.000 abstract 3
150000003672 ureas Chemical class 0.000 abstract 2
ZJEBGSGYSRSENA-UHFFFAOYSA-N 1-tert-butyl-3-(2,3-dihydrothiophen-4-yl)urea Chemical compound CC(C)(C)NC(=O)NC1=CSCC1 ZJEBGSGYSRSENA-UHFFFAOYSA-N 0.000 abstract 1
241001465754 Metazoa Species 0.000 abstract 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
230000003276 anti-hypertensive effect Effects 0.000 abstract 1
239000004202 carbamide Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
- C07D333/48—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D331/00—Heterocyclic compounds containing rings of less than five members, having one sulfur atom as the only ring hetero atom
- C07D331/04—Four-membered rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IE865/75A 1974-04-17 1975-04-17 Thienyl and thietyl compounds IE41143B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US46169974A	1974-04-17	1974-04-17
US05/555,307 US4009847A (en)	1974-04-17	1975-03-11	1-Tertiary-alkyl-3-(substituted thienyl)ureas and 1-tertiary-alkyl-3-(substituted thietyl)ureas as antihypertensive agents

Publications (2)

Publication Number	Publication Date
IE41143L IE41143L (en)	1975-10-17
IE41143B1 true IE41143B1 (en)	1979-10-24

Family

ID=27040095

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IE865/75A IE41143B1 (en)	1974-04-17	1975-04-17	Thienyl and thietyl compounds

Country Status (21)

Country	Link
US (1)	US4009847A (2)
JP (1)	JPS50148349A (2)
AR (1)	AR208545A1 (2)
CA (1)	CA1047042A (2)
CH (1)	CH611292A5 (2)
DD (1)	DD117223A5 (2)
DE (1)	DE2516554A1 (2)
DK (1)	DK164175A (2)
ES (1)	ES436648A1 (2)
FI (1)	FI751128A7 (2)
FR (1)	FR2267773B1 (2)
GB (1)	GB1461209A (2)
HU (1)	HU173052B (2)
IE (1)	IE41143B1 (2)
IL (1)	IL47095A (2)
LU (1)	LU72306A1 (2)
NL (1)	NL7504570A (2)
NO (1)	NO144071C (2)
PH (1)	PH11722A (2)
SE (1)	SE417965B (2)
YU (1)	YU96075A (2)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4156738A (en) *	1977-10-07	1979-05-29	E. I. Du Pont De Nemours And Company	Ureidonitriles useful as antihypertensives
US6187799B1 (en) *	1997-05-23	2001-02-13	Onyx Pharmaceuticals	Inhibition of raf kinase activity using aryl ureas
US6344476B1 (en)	1997-05-23	2002-02-05	Bayer Corporation	Inhibition of p38 kinase activity by aryl ureas
US20080300281A1 (en) *	1997-12-22	2008-12-04	Jacques Dumas	Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas
US7329670B1 (en)	1997-12-22	2008-02-12	Bayer Pharmaceuticals Corporation	Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
US7517880B2 (en) *	1997-12-22	2009-04-14	Bayer Pharmaceuticals Corporation	Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
US20080269265A1 (en) *	1998-12-22	2008-10-30	Scott Miller	Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas
US7928239B2 (en)	1999-01-13	2011-04-19	Bayer Healthcare Llc	Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas
US7351834B1 (en)	1999-01-13	2008-04-01	Bayer Pharmaceuticals Corporation	ω-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US8124630B2 (en)	1999-01-13	2012-02-28	Bayer Healthcare Llc	ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
WO2000042012A1 (en)	1999-01-13	2000-07-20	Bayer Corporation	φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS
ATE538794T1 (de) *	1999-01-13	2012-01-15	Bayer Healthcare Llc	Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer
US7235576B1 (en)	2001-01-12	2007-06-26	Bayer Pharmaceuticals Corporation	Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US7371763B2 (en) *	2001-04-20	2008-05-13	Bayer Pharmaceuticals Corporation	Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
JP4982685B2 (ja) *	2001-12-03	2012-07-25	バイエル、ファーマシューテイカルズ、コーポレイション	ヒトがんを処置するための他の細胞毒剤又は細胞増殖抑制剤と組合わせたアリール尿素化合物
US20080108672A1 (en) *	2002-01-11	2008-05-08	Bernd Riedl	Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
MXPA04007830A (es) *	2002-02-11	2005-07-01	Bayer Pharmaceuticals Corp	Arilureas como inhibidores de cinasa.
MXPA04007832A (es)	2002-02-11	2005-09-08	Bayer Pharmaceuticals Corp	Aril-ureas con actividad inhibitoria de angiogenesis.
WO2003068229A1 (en) *	2002-02-11	2003-08-21	Bayer Pharmaceuticals Corporation	Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors
US20040023961A1 (en) *	2002-02-11	2004-02-05	Bayer Corporation	Aryl ureas with raf kinase and angiogenisis inhibiting activity
US7557129B2 (en)	2003-02-28	2009-07-07	Bayer Healthcare Llc	Cyanopyridine derivatives useful in the treatment of cancer and other disorders
WO2004113274A2 (en) *	2003-05-20	2004-12-29	Bayer Pharmaceuticals Corporation	Diaryl ureas with kinase inhibiting activity
EA010485B1 (ru) *	2003-07-23	2008-10-30	Байер Фамэсьютиклс Копэрейшн	Производное n,n'-дифенилмочевины, фармацевтическая композиция (варианты) и способ лечения и предупреждения заболеваний и состояний с его использованием (варианты)
CN101010315A (zh) *	2004-04-30	2007-08-01	拜耳制药公司	用于治疗癌症的取代的吡唑基脲衍生物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH452475A (de) *	1965-05-20	1968-05-31	Bayer Ag	Verfahren zum Färben und Bedrucken von synthetischem Textilmaterial mit Anthrachinonfarbstoffen

1975
- 1975-03-11 US US05/555,307 patent/US4009847A/en not_active Expired - Lifetime
- 1975-03-26 SE SE7503523A patent/SE417965B/xx unknown
- 1975-04-15 CA CA224,634A patent/CA1047042A/en not_active Expired
- 1975-04-15 IL IL47095A patent/IL47095A/xx unknown
- 1975-04-16 NO NO751351A patent/NO144071C/no unknown
- 1975-04-16 PH PH17061A patent/PH11722A/en unknown
- 1975-04-16 DE DE19752516554 patent/DE2516554A1/de not_active Withdrawn
- 1975-04-16 GB GB1567175A patent/GB1461209A/en not_active Expired
- 1975-04-16 FR FR7511796A patent/FR2267773B1/fr not_active Expired
- 1975-04-16 DD DD185482A patent/DD117223A5/xx unknown
- 1975-04-16 YU YU00960/75A patent/YU96075A/xx unknown
- 1975-04-16 FI FI751128A patent/FI751128A7/fi not_active Application Discontinuation
- 1975-04-16 DK DK164175A patent/DK164175A/da not_active IP Right Cessation
- 1975-04-16 ES ES436648A patent/ES436648A1/es not_active Expired
- 1975-04-16 HU HU75DU237A patent/HU173052B/hu unknown
- 1975-04-16 AR AR258396A patent/AR208545A1/es active
- 1975-04-17 NL NL7504570A patent/NL7504570A/xx not_active Application Discontinuation
- 1975-04-17 JP JP50045924A patent/JPS50148349A/ja active Pending
- 1975-04-17 LU LU72306A patent/LU72306A1/xx unknown
- 1975-04-17 IE IE865/75A patent/IE41143B1/xx unknown
- 1975-04-17 CH CH494875A patent/CH611292A5/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE2516554A1 (de)	1975-10-30
AU8013575A (en)	1976-10-21
DK164175A (da)	1975-10-18
IL47095A0 (en)	1975-06-25
GB1461209A (en)	1977-01-13
FI751128A7 (2)	1975-10-18
IE41143L (en)	1975-10-17
DD117223A5 (2)	1976-01-05
AR208545A1 (es)	1977-02-15
YU96075A (en)	1983-04-27
NO751351L (2)	1975-10-20
IL47095A (en)	1978-03-10
JPS50148349A (2)	1975-11-27
NO144071B (no)	1981-03-09
LU72306A1 (2)	1976-03-17
ES436648A1 (es)	1977-08-01
SE417965B (sv)	1981-04-27
NO144071C (no)	1981-06-17
FR2267773A1 (2)	1975-11-14
HU173052B (hu)	1979-02-28
PH11722A (en)	1978-05-30
NL7504570A (nl)	1975-10-21
SE7503523L (sv)	1975-10-20
CH611292A5 (2)	1979-05-31
US4009847A (en)	1977-03-01
CA1047042A (en)	1979-01-23
FR2267773B1 (2)	1978-08-18

Publication	Publication Date	Title
IE41143B1 (en)	1979-10-24	Thienyl and thietyl compounds
AU503525B2 (en)	1979-09-06	Guanidines, thioureas and 2, 2-diamino-1-nitroethylene derivatives
IE45170L (en)	1978-01-20	Ureas and thioureas
PH12321A (en)	1979-01-16	Water-soluble,non-ionixing derivatives of 2,4,6-triiodo-isophthalic acid
IL52280A (en)	1981-07-31	6-(cyclic polymethylene imine)-methyleneamino-penicillanic acid derivatives,cyclic polymethylene imine intermediates therefor and pharmaceutical compositions containing said penicillanic acid derivatives
IE41209B1 (en)	1979-11-07	Substituded chalcones
IL44625A (en)	1978-07-31	Diuretic and antihypertensive compositions containing certain pyrazole derivatives
IE41440L (en)	1976-02-03	Thiatetracyclines
IE40510L (en)	1975-02-17	Cephalosporin derivatives
CA1014564A (en)	1977-07-26	Derivatives of 1,3-benzodioxole-2-carboxylic acid
GB1548466A (en)	1979-07-18	Urea derivatives having pharmacological activity and compositions containing the same
IE40593B1 (en)	1979-07-04	Novel piperazine derivatives and compositions containing them for treating parkinson's disease
FR2303021A1 (fr)	1976-10-01	Complexes d'enzymes
IE39049L (en)	1974-09-03	1, 4-dihydroquinolines.
GB1547826A (en)	1979-06-27	Pfarmaceutical compositions having diuretic and anthypertensive activity
IL47761A (en)	1979-07-25	9-hydroxy-19,20-bis-nor-prostanic acid and derivatives andpharmaceutical compositions containing them
IL46375A (en)	1982-04-30	4,5,6,7-tetrahydrobenzo-(b)thienyl and 5,6,7,8-tetrahydro-4h-cyclohepta(b)thienyl urea derivatives,their preparation and animal feed compositions containing them
IL45778A0 (en)	1974-12-31	Diuretic formulations comprising indanyloxyacetic acid derivatives
IE34594B1 (en)	1975-06-25	Methods of and compositions for the killing of weeds
IE39496L (en)	1974-12-15	5''-amino-4', 5''-dideoxy-ambutyrosin a.
IL44624A0 (en)	1974-06-30	Diuretic and antihypertensive compositions containing certain pyrazole derivatives
IL51965A0 (en)	1977-06-30	Novel urea derivatives their production and pesticidal compositions containing them
JPS5289678A (en)	1977-07-27	Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil
IE870244L (en)	1987-07-31	Platinum complexes
JPS52139056A (en)	1977-11-19	Preparation of 11tertiary alkyll33 substituted furyl urea