JPS50148349A - - Google Patents
Info
- Publication number
- JPS50148349A JPS50148349A JP50045924A JP4592475A JPS50148349A JP S50148349 A JPS50148349 A JP S50148349A JP 50045924 A JP50045924 A JP 50045924A JP 4592475 A JP4592475 A JP 4592475A JP S50148349 A JPS50148349 A JP S50148349A
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D331/00—Heterocyclic compounds containing rings of less than five members, having one sulfur atom as the only ring hetero atom
- C07D331/04—Four-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
- C07D333/48—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46169974A | 1974-04-17 | 1974-04-17 | |
| US05/555,307 US4009847A (en) | 1974-04-17 | 1975-03-11 | 1-Tertiary-alkyl-3-(substituted thienyl)ureas and 1-tertiary-alkyl-3-(substituted thietyl)ureas as antihypertensive agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS50148349A true JPS50148349A (2) | 1975-11-27 |
Family
ID=27040095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50045924A Pending JPS50148349A (2) | 1974-04-17 | 1975-04-17 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4009847A (2) |
| JP (1) | JPS50148349A (2) |
| AR (1) | AR208545A1 (2) |
| CA (1) | CA1047042A (2) |
| CH (1) | CH611292A5 (2) |
| DD (1) | DD117223A5 (2) |
| DE (1) | DE2516554A1 (2) |
| DK (1) | DK164175A (2) |
| ES (1) | ES436648A1 (2) |
| FI (1) | FI751128A7 (2) |
| FR (1) | FR2267773B1 (2) |
| GB (1) | GB1461209A (2) |
| HU (1) | HU173052B (2) |
| IE (1) | IE41143B1 (2) |
| IL (1) | IL47095A (2) |
| LU (1) | LU72306A1 (2) |
| NL (1) | NL7504570A (2) |
| NO (1) | NO144071C (2) |
| PH (1) | PH11722A (2) |
| SE (1) | SE417965B (2) |
| YU (1) | YU96075A (2) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4156738A (en) * | 1977-10-07 | 1979-05-29 | E. I. Du Pont De Nemours And Company | Ureidonitriles useful as antihypertensives |
| US6187799B1 (en) * | 1997-05-23 | 2001-02-13 | Onyx Pharmaceuticals | Inhibition of raf kinase activity using aryl ureas |
| US6344476B1 (en) | 1997-05-23 | 2002-02-05 | Bayer Corporation | Inhibition of p38 kinase activity by aryl ureas |
| US20080300281A1 (en) * | 1997-12-22 | 2008-12-04 | Jacques Dumas | Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas |
| US7329670B1 (en) | 1997-12-22 | 2008-02-12 | Bayer Pharmaceuticals Corporation | Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas |
| US7517880B2 (en) * | 1997-12-22 | 2009-04-14 | Bayer Pharmaceuticals Corporation | Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas |
| US20080269265A1 (en) * | 1998-12-22 | 2008-10-30 | Scott Miller | Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas |
| US7928239B2 (en) | 1999-01-13 | 2011-04-19 | Bayer Healthcare Llc | Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas |
| US7351834B1 (en) | 1999-01-13 | 2008-04-01 | Bayer Pharmaceuticals Corporation | ω-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| WO2000042012A1 (en) | 1999-01-13 | 2000-07-20 | Bayer Corporation | φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS |
| ATE538794T1 (de) * | 1999-01-13 | 2012-01-15 | Bayer Healthcare Llc | Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer |
| US7235576B1 (en) | 2001-01-12 | 2007-06-26 | Bayer Pharmaceuticals Corporation | Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| US7371763B2 (en) * | 2001-04-20 | 2008-05-13 | Bayer Pharmaceuticals Corporation | Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas |
| JP4982685B2 (ja) * | 2001-12-03 | 2012-07-25 | バイエル、ファーマシューテイカルズ、コーポレイション | ヒトがんを処置するための他の細胞毒剤又は細胞増殖抑制剤と組合わせたアリール尿素化合物 |
| US20080108672A1 (en) * | 2002-01-11 | 2008-05-08 | Bernd Riedl | Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors |
| MXPA04007830A (es) * | 2002-02-11 | 2005-07-01 | Bayer Pharmaceuticals Corp | Arilureas como inhibidores de cinasa. |
| MXPA04007832A (es) | 2002-02-11 | 2005-09-08 | Bayer Pharmaceuticals Corp | Aril-ureas con actividad inhibitoria de angiogenesis. |
| WO2003068229A1 (en) * | 2002-02-11 | 2003-08-21 | Bayer Pharmaceuticals Corporation | Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors |
| US20040023961A1 (en) * | 2002-02-11 | 2004-02-05 | Bayer Corporation | Aryl ureas with raf kinase and angiogenisis inhibiting activity |
| US7557129B2 (en) | 2003-02-28 | 2009-07-07 | Bayer Healthcare Llc | Cyanopyridine derivatives useful in the treatment of cancer and other disorders |
| WO2004113274A2 (en) * | 2003-05-20 | 2004-12-29 | Bayer Pharmaceuticals Corporation | Diaryl ureas with kinase inhibiting activity |
| EA010485B1 (ru) * | 2003-07-23 | 2008-10-30 | Байер Фамэсьютиклс Копэрейшн | Производное n,n'-дифенилмочевины, фармацевтическая композиция (варианты) и способ лечения и предупреждения заболеваний и состояний с его использованием (варианты) |
| CN101010315A (zh) * | 2004-04-30 | 2007-08-01 | 拜耳制药公司 | 用于治疗癌症的取代的吡唑基脲衍生物 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH452475A (de) * | 1965-05-20 | 1968-05-31 | Bayer Ag | Verfahren zum Färben und Bedrucken von synthetischem Textilmaterial mit Anthrachinonfarbstoffen |
-
1975
- 1975-03-11 US US05/555,307 patent/US4009847A/en not_active Expired - Lifetime
- 1975-03-26 SE SE7503523A patent/SE417965B/xx unknown
- 1975-04-15 CA CA224,634A patent/CA1047042A/en not_active Expired
- 1975-04-15 IL IL47095A patent/IL47095A/xx unknown
- 1975-04-16 NO NO751351A patent/NO144071C/no unknown
- 1975-04-16 PH PH17061A patent/PH11722A/en unknown
- 1975-04-16 DE DE19752516554 patent/DE2516554A1/de not_active Withdrawn
- 1975-04-16 GB GB1567175A patent/GB1461209A/en not_active Expired
- 1975-04-16 FR FR7511796A patent/FR2267773B1/fr not_active Expired
- 1975-04-16 DD DD185482A patent/DD117223A5/xx unknown
- 1975-04-16 YU YU00960/75A patent/YU96075A/xx unknown
- 1975-04-16 FI FI751128A patent/FI751128A7/fi not_active Application Discontinuation
- 1975-04-16 DK DK164175A patent/DK164175A/da not_active IP Right Cessation
- 1975-04-16 ES ES436648A patent/ES436648A1/es not_active Expired
- 1975-04-16 HU HU75DU237A patent/HU173052B/hu unknown
- 1975-04-16 AR AR258396A patent/AR208545A1/es active
- 1975-04-17 NL NL7504570A patent/NL7504570A/xx not_active Application Discontinuation
- 1975-04-17 JP JP50045924A patent/JPS50148349A/ja active Pending
- 1975-04-17 LU LU72306A patent/LU72306A1/xx unknown
- 1975-04-17 IE IE865/75A patent/IE41143B1/xx unknown
- 1975-04-17 CH CH494875A patent/CH611292A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IE41143B1 (en) | 1979-10-24 |
| DE2516554A1 (de) | 1975-10-30 |
| AU8013575A (en) | 1976-10-21 |
| DK164175A (da) | 1975-10-18 |
| IL47095A0 (en) | 1975-06-25 |
| GB1461209A (en) | 1977-01-13 |
| FI751128A7 (2) | 1975-10-18 |
| IE41143L (en) | 1975-10-17 |
| DD117223A5 (2) | 1976-01-05 |
| AR208545A1 (es) | 1977-02-15 |
| YU96075A (en) | 1983-04-27 |
| NO751351L (2) | 1975-10-20 |
| IL47095A (en) | 1978-03-10 |
| NO144071B (no) | 1981-03-09 |
| LU72306A1 (2) | 1976-03-17 |
| ES436648A1 (es) | 1977-08-01 |
| SE417965B (sv) | 1981-04-27 |
| NO144071C (no) | 1981-06-17 |
| FR2267773A1 (2) | 1975-11-14 |
| HU173052B (hu) | 1979-02-28 |
| PH11722A (en) | 1978-05-30 |
| NL7504570A (nl) | 1975-10-21 |
| SE7503523L (sv) | 1975-10-20 |
| CH611292A5 (2) | 1979-05-31 |
| US4009847A (en) | 1977-03-01 |
| CA1047042A (en) | 1979-01-23 |
| FR2267773B1 (2) | 1978-08-18 |