IE43284L - Benzyloxyalkyl derivatives - Google Patents

Benzyloxyalkyl derivatives

Info

Publication number
IE43284L
IE43284L IE761746A IE174676A IE43284L IE 43284 L IE43284 L IE 43284L IE 761746 A IE761746 A IE 761746A IE 174676 A IE174676 A IE 174676A IE 43284 L IE43284 L IE 43284L
Authority
IE
Ireland
Prior art keywords
formula
benzyloxyalkyl
derivatives
benzyloxyalkyl derivatives
gb1488646a
Prior art date
Application number
IE761746A
Other versions
IE43284B1 (en
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of IE43284L publication Critical patent/IE43284L/en
Publication of IE43284B1 publication Critical patent/IE43284B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Aminoalkoxyphenylalkyl benzyl ethers of the formula I are prepared by reacting a compound of the formula II with one of the formula III. The symbols in the formulae have the meaning stated in Claim 1. The compounds of the formula I and their pharmacologically compatible salts display lower toxicity, and pronounced antiinflammatory and good analgesic effects. <IMAGE> [GB1488646A]
IE1746/76A 1975-09-09 1976-08-06 Benzyloxyalkyl derivatives IE43284B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2539941A DE2539941C2 (en) 1975-09-09 1975-09-09 Basic benzyloxyalkyl derivatives, their preparation and pharmaceuticals containing these compounds

Publications (2)

Publication Number Publication Date
IE43284L true IE43284L (en) 1977-03-09
IE43284B1 IE43284B1 (en) 1981-01-28

Family

ID=5955902

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1746/76A IE43284B1 (en) 1975-09-09 1976-08-06 Benzyloxyalkyl derivatives

Country Status (14)

Country Link
JP (1) JPS5233639A (en)
AT (1) AT346306B (en)
AU (1) AU502573B2 (en)
BE (1) BE845964A (en)
CH (1) CH628613A5 (en)
DE (1) DE2539941C2 (en)
DK (1) DK153142C (en)
ES (1) ES451158A1 (en)
FR (1) FR2323377A1 (en)
GB (1) GB1488646A (en)
IE (1) IE43284B1 (en)
LU (1) LU75735A1 (en)
NL (1) NL186238C (en)
SE (1) SE430056B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK368687A (en) * 1986-11-21 1988-05-22 Cheminova As AMINOALCYLED HYDROXY COMPOUNDS AND THEIR USE AS FUNGICIDES
JPH032229U (en) * 1989-05-26 1991-01-10

Also Published As

Publication number Publication date
ES451158A1 (en) 1977-12-01
IE43284B1 (en) 1981-01-28
GB1488646A (en) 1977-10-12
BE845964A (en) 1977-03-08
JPS5233639A (en) 1977-03-14
FR2323377B1 (en) 1978-11-17
NL186238C (en) 1990-10-16
LU75735A1 (en) 1977-06-15
SE7609746L (en) 1977-03-10
AU1736176A (en) 1978-03-09
ATA668876A (en) 1978-03-15
CH628613A5 (en) 1982-03-15
DK153142B (en) 1988-06-20
JPS6121940B2 (en) 1986-05-29
DE2539941C2 (en) 1984-04-26
DK403576A (en) 1977-03-10
NL186238B (en) 1990-05-16
FR2323377A1 (en) 1977-04-08
AT346306B (en) 1978-11-10
DE2539941A1 (en) 1977-03-17
DK153142C (en) 1988-11-07
NL7610040A (en) 1977-03-11
AU502573B2 (en) 1979-08-02
SE430056B (en) 1983-10-17

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