IE46916B1 - New pharmacologically-active 4-acetamidophenyl -(2-methyl-ind(en/ol)-3-yl)-acetates, process for their preparation, and pharmaceutical compositions incorporating them - Google Patents

New pharmacologically-active 4-acetamidophenyl -(2-methyl-ind(en/ol)-3-yl)-acetates, process for their preparation, and pharmaceutical compositions incorporating them

Info

Publication number
IE46916B1
IE46916B1 IE1106/78A IE110678A IE46916B1 IE 46916 B1 IE46916 B1 IE 46916B1 IE 1106/78 A IE1106/78 A IE 1106/78A IE 110678 A IE110678 A IE 110678A IE 46916 B1 IE46916 B1 IE 46916B1
Authority
IE
Ireland
Prior art keywords
general formula
methyl
acetamidophenyl
ind
acetate
Prior art date
Application number
IE1106/78A
Other languages
English (en)
Other versions
IE781106L (en
Original Assignee
Sterwin Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterwin Ag filed Critical Sterwin Ag
Publication of IE781106L publication Critical patent/IE781106L/xx
Publication of IE46916B1 publication Critical patent/IE46916B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IE1106/78A 1977-06-02 1978-06-01 New pharmacologically-active 4-acetamidophenyl -(2-methyl-ind(en/ol)-3-yl)-acetates, process for their preparation, and pharmaceutical compositions incorporating them IE46916B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB23320/77A GB1587070A (en) 1977-06-02 1977-06-02 Pharmacologically-active 4-acetamidophenyl a-(2-methyl-ind(en/ol)-3-yl)-acetates processes for their preparation and pharmaceutical composition incorporating them

Publications (2)

Publication Number Publication Date
IE781106L IE781106L (en) 1978-12-02
IE46916B1 true IE46916B1 (en) 1983-11-02

Family

ID=10193704

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1106/78A IE46916B1 (en) 1977-06-02 1978-06-01 New pharmacologically-active 4-acetamidophenyl -(2-methyl-ind(en/ol)-3-yl)-acetates, process for their preparation, and pharmaceutical compositions incorporating them

Country Status (13)

Country Link
AT (1) AT364822B (fr)
BE (1) BE867760A (fr)
CH (1) CH644594A5 (fr)
DE (1) DE2824056A1 (fr)
DK (1) DK243978A (fr)
FI (2) FI781760A7 (fr)
FR (1) FR2392975A1 (fr)
GB (1) GB1587070A (fr)
IE (1) IE46916B1 (fr)
LU (1) LU79756A1 (fr)
NL (1) NL175818C (fr)
NO (1) NO149064C (fr)
SE (1) SE429340B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0078765B1 (fr) * 1981-11-02 1986-02-26 Cermol S.A. Dérivés de p-acylaminophénol à effet thérapeutique, procédé pour leur préparation, et composition à effet thérapeutique contenant lesdits dérivés à titre d'ingrédients pharmacologiquement actifs
FR2835433B1 (fr) * 2002-02-01 2006-02-17 Richard Lab M Utilisation de la 1-(-4-chlorobenzoyl)-5methoxy-2-methyl-1h- indole-3acetic 4-(acetylamino)phenylester pour la fabrication d'un medicament destine a inhiber exclusivement la cox2

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2234651C3 (de) * 1972-07-14 1978-11-09 Troponwerke Gmbh & Co Kg, 5000 Koeln Eckige Klammer auf l-(p-Chlorbenzoyl)-5-methoxy-2-methyl-3-indol] -acetoxj essigsaure, ihre Salze mit Basen, Verfahren zu ihrer Herstellung sowie pharmakologische Zubereitungen

Also Published As

Publication number Publication date
NO781906L (no) 1978-12-05
SE429340B (sv) 1983-08-29
NO149064B (no) 1983-10-31
NL175818C (nl) 1985-01-02
ATA398678A (de) 1981-04-15
NL7805966A (nl) 1978-12-05
FI781761A7 (fi) 1978-12-03
FI781760A7 (fi) 1978-12-03
DK243978A (da) 1978-12-03
BE867760A (fr) 1978-10-02
NL175818B (nl) 1984-08-01
GB1587070A (en) 1981-03-25
FR2392975B1 (fr) 1982-12-31
IE781106L (en) 1978-12-02
NO149064C (no) 1984-02-22
SE7806461L (sv) 1979-02-09
AT364822B (de) 1981-11-25
DE2824056A1 (de) 1978-12-14
CH644594A5 (en) 1984-08-15
FR2392975A1 (fr) 1978-12-29
LU79756A1 (fr) 1978-11-28

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