IE58361B1 - Ijectable vitamin compostion - Google Patents

Ijectable vitamin compostion

Info

Publication number: IE58361B1
Authority: IE; Ireland
Prior art keywords: vitamin; tocopherol; solvent; iron; sulfate
Prior art date: 1983-05-03

Application number

IE108784A

Other languages

English (en)

Other versions

IE841087L (en

Original Assignee

Ssm Int Chem Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-05-03

Filing date

1984-05-02

Publication date

1993-09-08

1984-05-02 Application filed by Ssm Int Chem Co Ltd filed Critical Ssm Int Chem Co Ltd

1984-11-03 Publication of IE841087L publication Critical patent/IE841087L/xx

1993-09-08 Publication of IE58361B1 publication Critical patent/IE58361B1/en

Links

229940088594 vitamin Drugs 0.000 title claims description 22
229930003231 vitamin Natural products 0.000 title claims description 22
235000013343 vitamin Nutrition 0.000 title claims description 22
239000011782 vitamin Substances 0.000 title claims description 22
150000003722 vitamin derivatives Chemical class 0.000 title claims description 22
239000000203 mixture Substances 0.000 claims abstract description 25
XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims abstract description 20
229910052742 iron Inorganic materials 0.000 claims abstract description 10
229910052751 metal Inorganic materials 0.000 claims abstract description 9
239000002184 metal Substances 0.000 claims abstract description 9
150000002739 metals Chemical class 0.000 claims abstract description 9
241000282849 Ruminantia Species 0.000 claims abstract description 7
239000000470 constituent Substances 0.000 claims abstract description 7
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims abstract description 6
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 6
229910052802 copper Inorganic materials 0.000 claims abstract description 6
239000010949 copper Substances 0.000 claims abstract description 6
229910052725 zinc Inorganic materials 0.000 claims abstract description 6
239000011701 zinc Substances 0.000 claims abstract description 6
239000011573 trace mineral Substances 0.000 claims abstract description 4
235000013619 trace mineral Nutrition 0.000 claims abstract description 4
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical group CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 19
239000002904 solvent Substances 0.000 claims description 11
GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 10
PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims description 10
FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 10
UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 claims description 10
TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims description 8
UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 8
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims description 6
RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Chemical compound N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 claims description 6
229960004063 propylene glycol Drugs 0.000 claims description 6
235000013772 propylene glycol Nutrition 0.000 claims description 6
235000005282 vitamin D3 Nutrition 0.000 claims description 6
239000011647 vitamin D3 Substances 0.000 claims description 6
QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 claims description 6
229940021056 vitamin d3 Drugs 0.000 claims description 6
GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 6
FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 5
AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims description 5
AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims description 5
235000019169 all-trans-retinol Nutrition 0.000 claims description 5
239000011717 all-trans-retinol Substances 0.000 claims description 5
229910052500 inorganic mineral Inorganic materials 0.000 claims description 5
239000011707 mineral Substances 0.000 claims description 5
235000010755 mineral Nutrition 0.000 claims description 5
229960003512 nicotinic acid Drugs 0.000 claims description 5
239000011664 nicotinic acid Substances 0.000 claims description 5
235000001968 nicotinic acid Nutrition 0.000 claims description 5
229960002477 riboflavin Drugs 0.000 claims description 5
229960005322 streptomycin Drugs 0.000 claims description 5
AEDORKVKMIVLBW-BLDDREHASA-N 3-oxo-3-[[(2r,3s,4s,5r,6r)-3,4,5-trihydroxy-6-[[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methoxy]oxan-2-yl]methoxy]propanoic acid Chemical compound OCC1=C(O)C(C)=NC=C1CO[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](COC(=O)CC(O)=O)O1 AEDORKVKMIVLBW-BLDDREHASA-N 0.000 claims description 4
SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims description 4
235000001815 DL-alpha-tocopherol Nutrition 0.000 claims description 4
239000011627 DL-alpha-tocopherol Substances 0.000 claims description 4
FCASKLHVRFDIJB-UHFFFAOYSA-N Riboflavine Natural products Cc1cc2N=C3C(NC(=O)NC3=O)N(CC(O)C(O)C(O)CO)c2cc1C FCASKLHVRFDIJB-UHFFFAOYSA-N 0.000 claims description 4
KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims description 4
239000004327 boric acid Substances 0.000 claims description 4
ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 claims description 4
229910000366 copper(II) sulfate Inorganic materials 0.000 claims description 4
UEGPKNKPLBYCNK-UHFFFAOYSA-L magnesium acetate Chemical compound [Mg+2].CC([O-])=O.CC([O-])=O UEGPKNKPLBYCNK-UHFFFAOYSA-L 0.000 claims description 4
229910001629 magnesium chloride Inorganic materials 0.000 claims description 4
SEQVSYFEKVIYCP-UHFFFAOYSA-L magnesium hypophosphite Chemical compound [Mg+2].[O-]P=O.[O-]P=O SEQVSYFEKVIYCP-UHFFFAOYSA-L 0.000 claims description 4
229910001381 magnesium hypophosphite Inorganic materials 0.000 claims description 4
239000011702 manganese sulphate Substances 0.000 claims description 4
235000007079 manganese sulphate Nutrition 0.000 claims description 4
SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 claims description 4
235000020957 pantothenol Nutrition 0.000 claims description 4
239000011619 pantothenol Substances 0.000 claims description 4
235000019171 pyridoxine hydrochloride Nutrition 0.000 claims description 4
239000011764 pyridoxine hydrochloride Substances 0.000 claims description 4
235000019192 riboflavin Nutrition 0.000 claims description 4
239000002151 riboflavin Substances 0.000 claims description 4
229940082569 selenite Drugs 0.000 claims description 4
MCAHWIHFGHIESP-UHFFFAOYSA-L selenite(2-) Chemical compound [O-][Se]([O-])=O MCAHWIHFGHIESP-UHFFFAOYSA-L 0.000 claims description 4
239000011734 sodium Substances 0.000 claims description 4
229910052708 sodium Inorganic materials 0.000 claims description 4
-1 sodium anhydride Chemical class 0.000 claims description 4
235000017557 sodium bicarbonate Nutrition 0.000 claims description 4
229910000030 sodium bicarbonate Inorganic materials 0.000 claims description 4
235000019157 thiamine Nutrition 0.000 claims description 4
JZRWCGZRTZMZEH-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 claims description 4
239000011721 thiamine Substances 0.000 claims description 4
229940011671 vitamin b6 Drugs 0.000 claims description 4
NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims description 4
229960001763 zinc sulfate Drugs 0.000 claims description 4
229910000368 zinc sulfate Inorganic materials 0.000 claims description 4
RPERJPYDELTDMR-UHFFFAOYSA-K 2-hydroxyethyl(trimethyl)azanium;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound C[N+](C)(C)CCO.C[N+](C)(C)CCO.C[N+](C)(C)CCO.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O RPERJPYDELTDMR-UHFFFAOYSA-K 0.000 claims description 3
229940087168 alpha tocopherol Drugs 0.000 claims description 3
239000004227 calcium gluconate Substances 0.000 claims description 3
229960004494 calcium gluconate Drugs 0.000 claims description 3
235000013927 calcium gluconate Nutrition 0.000 claims description 3
NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 claims description 3
229960003257 choline citrate Drugs 0.000 claims description 3
GVPFVAHMJGGAJG-UHFFFAOYSA-L cobalt dichloride Chemical compound [Cl-].[Cl-].[Co+2] GVPFVAHMJGGAJG-UHFFFAOYSA-L 0.000 claims description 3
229940097267 cobaltous chloride Drugs 0.000 claims description 3
229960002104 cyanocobalamin Drugs 0.000 claims description 3
235000000639 cyanocobalamin Nutrition 0.000 claims description 3
239000011666 cyanocobalamin Substances 0.000 claims description 3
229940099596 manganese sulfate Drugs 0.000 claims description 3
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 3
229960000984 tocofersolan Drugs 0.000 claims description 3
239000002076 α-tocopherol Substances 0.000 claims description 3
235000004835 α-tocopherol Nutrition 0.000 claims description 3
FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 2
MECHNRXZTMCUDQ-UHFFFAOYSA-N Vitamin D2 Natural products C1CCC2(C)C(C(C)C=CC(C)C(C)C)CCC2C1=CC=C1CC(O)CCC1=C MECHNRXZTMCUDQ-UHFFFAOYSA-N 0.000 claims 2
229960002061 ergocalciferol Drugs 0.000 claims 2
229960000367 inositol Drugs 0.000 claims 2
CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 claims 2
229930182817 methionine Natural products 0.000 claims 2
CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 claims 2
235000001892 vitamin D2 Nutrition 0.000 claims 2
239000011653 vitamin D2 Substances 0.000 claims 2
MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 claims 2
KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims 1
239000003242 anti bacterial agent Substances 0.000 abstract description 5
229940088710 antibiotic agent Drugs 0.000 abstract description 5
230000001225 therapeutic effect Effects 0.000 abstract description 3
230000035558 fertility Effects 0.000 abstract description 2
DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 abstract 1
238000007911 parenteral administration Methods 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 3
229930003427 Vitamin E Natural products 0.000 description 3
230000007812 deficiency Effects 0.000 description 3
230000001079 digestive effect Effects 0.000 description 3
WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 3
238000002347 injection Methods 0.000 description 3
239000007924 injection Substances 0.000 description 3
239000011669 selenium Substances 0.000 description 3
229910052711 selenium Inorganic materials 0.000 description 3
239000011709 vitamin E Substances 0.000 description 3
235000019165 vitamin E Nutrition 0.000 description 3
229940046009 vitamin E Drugs 0.000 description 3
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
235000001484 Trigonella foenum graecum Nutrition 0.000 description 2
244000250129 Trigonella foenum graecum Species 0.000 description 2
230000037396 body weight Effects 0.000 description 2
201000010099 disease Diseases 0.000 description 2
208000035475 disorder Diseases 0.000 description 2
230000000694 effects Effects 0.000 description 2
230000007257 malfunction Effects 0.000 description 2
210000003205 muscle Anatomy 0.000 description 2
208000007442 rickets Diseases 0.000 description 2
MECHNRXZTMCUDQ-AAGLSAJLSA-N (3z)-3-[(2e)-2-[1-[(e)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1h-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol Chemical compound C1CCC2(C)C(C(C)/C=C/C(C)C(C)C)CCC2\C1=C\C=C1\CC(O)CCC1=C MECHNRXZTMCUDQ-AAGLSAJLSA-N 0.000 description 1
208000032484 Accidental exposure to product Diseases 0.000 description 1
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
206010012735 Diarrhoea Diseases 0.000 description 1
241000372361 Hyaena Species 0.000 description 1
206010023126 Jaundice Diseases 0.000 description 1
241001465754 Metazoa Species 0.000 description 1
229930003471 Vitamin B2 Natural products 0.000 description 1
230000002159 abnormal effect Effects 0.000 description 1
229910021529 ammonia Inorganic materials 0.000 description 1
208000007502 anemia Diseases 0.000 description 1
229960005069 calcium Drugs 0.000 description 1
239000011575 calcium Substances 0.000 description 1
229910052791 calcium Inorganic materials 0.000 description 1
239000002775 capsule Substances 0.000 description 1
230000002802 cardiorespiratory effect Effects 0.000 description 1
239000000969 carrier Substances 0.000 description 1
230000015556 catabolic process Effects 0.000 description 1
MPMSMUBQXQALQI-UHFFFAOYSA-N cobalt phthalocyanine Chemical compound [Co+2].C12=CC=CC=C2C(N=C2[N-]C(C3=CC=CC=C32)=N2)=NC1=NC([C]1C=CC=CC1=1)=NC=1N=C1[C]3C=CC=CC3=C2[N-]1 MPMSMUBQXQALQI-UHFFFAOYSA-N 0.000 description 1
238000006731 degradation reaction Methods 0.000 description 1
238000011161 development Methods 0.000 description 1
230000018109 developmental process Effects 0.000 description 1
239000003085 diluting agent Substances 0.000 description 1
239000003814 drug Substances 0.000 description 1
230000002526 effect on cardiovascular system Effects 0.000 description 1
230000004720 fertilization Effects 0.000 description 1
210000001035 gastrointestinal tract Anatomy 0.000 description 1
239000007972 injectable composition Substances 0.000 description 1
238000007918 intramuscular administration Methods 0.000 description 1
230000001788 irregular Effects 0.000 description 1
239000007788 liquid Substances 0.000 description 1
210000004185 liver Anatomy 0.000 description 1
206010025482 malaise Diseases 0.000 description 1
239000004292 methyl p-hydroxybenzoate Substances 0.000 description 1
235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 1
LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 1
229960002216 methylparaben Drugs 0.000 description 1
238000012986 modification Methods 0.000 description 1
230000004048 modification Effects 0.000 description 1
201000000585 muscular atrophy Diseases 0.000 description 1
230000001473 noxious effect Effects 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
210000004767 rumen Anatomy 0.000 description 1
239000000243 solution Substances 0.000 description 1
238000001228 spectrum Methods 0.000 description 1
239000000126 substance Substances 0.000 description 1
229960001295 tocopherol Drugs 0.000 description 1
239000011732 tocopherol Substances 0.000 description 1
235000019164 vitamin B2 Nutrition 0.000 description 1
239000011716 vitamin B2 Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Inorganic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Diabetes (AREA)
Obesity (AREA)
Dermatology (AREA)
Gastroenterology & Hepatology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

IE108784A 1983-05-03 1984-05-02 Ijectable vitamin compostion IE58361B1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
LU84787		1983-05-03

Publications (2)

Publication Number	Publication Date
IE841087L IE841087L (en)	1984-11-03
IE58361B1 true IE58361B1 (en)	1993-09-08

Family

ID=19730091

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IE108784A IE58361B1 (en)	1983-05-03	1984-05-02	Ijectable vitamin compostion

Country Status (9)

Country	Link
EP (1)	EP0155941A1 (da)
JP (1)	JPH01500745A (da)
CA (1)	CA1226522A (da)
DK (1)	DK3685A (da)
IE (1)	IE58361B1 (da)
IT (1)	IT1180165B (da)
PT (1)	PT78541B (da)
WO (1)	WO1984004243A2 (da)
ZA (1)	ZA843279B (da)

Cited By (1)

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Publication number	Priority date	Publication date	Assignee	Title
WO2021007610A1 (en)	2019-07-12	2021-01-21	Chemvet Australia Pty Ltd	Injectable nutritional supplement

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US4600586A (en) *	1983-08-08	1986-07-15	Green Milton L	Livestock feed lot adaptation composition and method
FR2599967B1 (fr) *	1986-06-16	1989-03-31	Bfb Etudes Rech Experimentale	Utilisation de sel de zinc et de la vitamine b6 pour enrayer les processus alopeciques et/ou seborrheiques.
NZ222664A (en) *	1986-11-29	1990-06-26	Vesta Med Pty Ltd	Pharmaceutical compositions containing pyridoxal as a source of vitamin b6
FR2625414B1 (fr) *	1987-12-31	1990-06-01	Unicor Union Cooperatives Agri	Melange d'ingredients nutritionnels pour l'alimentation des ruminants
NZ272317A (en) *	1995-06-09	1997-07-27	Bomac Lab Ltd	Veterinary formulation; comprises calcium borogluconate, vitamin b12 or a derivative thereof and a carrier; treatment of milk fever in animals
WO1998006410A1 (en) *	1996-08-12	1998-02-19	Taisho Pharmaceutical Co., Ltd.	Zinc-containing composition
DE19731432C2 (de) *	1997-07-22	1999-07-15	Phoenix Lab Pharmazeutische Pr	Verwendung von Cholincitrat

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JPS5176436A (ja) *	1974-12-24	1976-07-02	Kumiai Chemical Industry Co	Dobutsuyohinketsuyobo chiryozai
JPS6039681B2 (ja) *	1976-01-01	1985-09-07	日本臓器製薬株式会社	デキストリン・クエン酸・第二鉄多核複合体及び該複合体を含有する非経口用鉄剤
EP0046409A1 (en) *	1980-08-20	1982-02-24	Erwin Günther Walliczek	A process for the preparation of a solution of a cuprous complex; solutions of the cuprous complexes for use in the therapeutic treatment of the human or animal body; and a method of therapeutic treatment of a plant
IL61080A0 (en) *	1980-09-19	1980-11-30	Garfinkel D	Pharmaceutical composition containing zinc ions

1984
- 1984-05-02 JP JP59501884A patent/JPH01500745A/ja active Pending
- 1984-05-02 EP EP84901728A patent/EP0155941A1/fr active Pending
- 1984-05-02 IE IE108784A patent/IE58361B1/en not_active IP Right Cessation
- 1984-05-02 IT IT20758/84A patent/IT1180165B/it active
- 1984-05-02 ZA ZA843279A patent/ZA843279B/xx unknown
- 1984-05-02 WO PCT/BE1984/000011 patent/WO1984004243A2/fr not_active Ceased
- 1984-05-02 CA CA000453414A patent/CA1226522A/fr not_active Expired
- 1984-05-03 PT PT78541A patent/PT78541B/pt not_active IP Right Cessation
1985
- 1985-01-03 DK DK3685A patent/DK3685A/da unknown

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2021007610A1 (en)	2019-07-12	2021-01-21	Chemvet Australia Pty Ltd	Injectable nutritional supplement
EP3996720A4 (en) *	2019-07-12	2023-05-10	Chemvet Australia Pty Ltd	INJECTABLE FOOD SUPPLEMENT
EP3996720B1 (en)	2019-07-12	2025-02-12	Chemvet Australia Pty Ltd	Injectable nutritional supplement

Also Published As

Publication number	Publication date
DK3685D0 (da)	1985-01-03
DK3685A (da)	1985-01-03
PT78541A (fr)	1984-06-01
ZA843279B (en)	1985-03-27
WO1984004243A3 (fr)	1985-03-14
JPH01500745A (ja)	1989-03-16
CA1226522A (fr)	1987-09-08
PT78541B (fr)	1986-07-14
WO1984004243A2 (fr)	1984-11-08
IT1180165B (it)	1987-09-23
IT8420758A1 (it)	1985-11-02
IE841087L (en)	1984-11-03
IT8420758A0 (it)	1984-05-02
EP0155941A1 (fr)	1985-10-02

Legal Events

Date	Code	Title	Description
1996-02-21	MM4A	Patent lapsed

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JPH10509729A (ja)	1998-09-22	骨粗鬆症治療サイクル用キット
Wadhwani	1952	Mitigation of Fluorosis (Experimental). Part I
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JPH033642B2 (da)	1991-01-21
US3129139A (en)	1964-04-14	Therapeutic composition
AU629520B2 (en)	1992-10-08	A medicament
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