IE59494B1 - 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6-dihydro-5--methyl-6-oxo-4h-imidazo(1,4-a)(1,4)benzodiazepine, a process for its preparation and pharmaceutical compositions - Google Patents

3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6-dihydro-5--methyl-6-oxo-4h-imidazo(1,4-a)(1,4)benzodiazepine, a process for its preparation and pharmaceutical compositions

Info

Publication number: IE59494B1
Authority: IE; Ireland
Prior art keywords: compound; benzodiazepine; cyclopropyl; oxo; imidazo
Prior art date: 1985-05-17

Application number

IE130686A

Other languages

English (en)

Other versions

IE861306L (en

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-05-17

Filing date

1986-05-16

Publication date

1994-02-23

1985-05-17 Priority claimed from DK220485A external-priority patent/DK220485D0/da

1985-08-12 Priority claimed from DK365985A external-priority patent/DK365985D0/da

1985-10-17 Priority claimed from DK476985A external-priority patent/DK476985D0/da

1986-05-16 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

1986-11-17 Publication of IE861306L publication Critical patent/IE861306L/en

1994-02-23 Publication of IE59494B1 publication Critical patent/IE59494B1/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Plural Heterocyclic Compounds (AREA)
Polyethers (AREA)
Phenolic Resins Or Amino Resins (AREA)
Polyesters Or Polycarbonates (AREA)

IE130686A 1985-05-17 1986-05-16 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6-dihydro-5--methyl-6-oxo-4h-imidazo(1,4-a)(1,4)benzodiazepine, a process for its preparation and pharmaceutical compositions IE59494B1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DK220485A DK220485D0 (da)	1985-05-17	1985-05-17	Nye oxadiazolylimidazobenzodiazepinderivater samt fremgangsmaade tilfremstilling heraf
DK365985A DK365985D0 (da)	1985-08-12	1985-08-12	Nye oxadiazolylimidazobenzodiazepinderivater samt fremgangsmaade tilfremstilling heraf
DK476985A DK476985D0 (da)	1985-10-17	1985-10-17	Fremgangsmaade til fremstilling af oxadiazolylderivater af imidazobenzodiazepiner og mellemprodukt til brug ved fremgangsmaaden

Publications (2)

Publication Number	Publication Date
IE861306L IE861306L (en)	1986-11-17
IE59494B1 true IE59494B1 (en)	1994-02-23

Family

ID=27221528

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IE130686A IE59494B1 (en)	1985-05-17	1986-05-16	3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6-dihydro-5--methyl-6-oxo-4h-imidazo(1,4-a)(1,4)benzodiazepine, a process for its preparation and pharmaceutical compositions

Country Status (16)

Country	Link
US (2)	US4622320A (de)
EP (1)	EP0201678B1 (de)
JP (1)	JPH01279877A (de)
AT (1)	ATE35266T1 (de)
AU (2)	AU590273B2 (de)
CA (2)	CA1256864A (de)
DE (2)	DE3660331D1 (de)
DK (2)	DK157194C (de)
ES (1)	ES8707205A1 (de)
FI (1)	FI82049C (de)
GR (1)	GR861260B (de)
IE (1)	IE59494B1 (de)
IL (1)	IL78790A (de)
NO (1)	NO163228C (de)
NZ (1)	NZ216202A (de)
PT (1)	PT82594B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI850191A7 (fi) *	1984-01-19	1985-07-20	Hoffmann La Roche	Imidatsodiatsepiini-johdannaisia.
US4771051A (en) *	1985-05-17	1988-09-13	A/S Ferrosan	3-substituted-4,5-dihydro-5-oxo imidazoquinazolines, their preparation, and their use in treating benzodiazepin receptor-related ailments
US4622320A (en) *	1985-05-17	1986-11-11	As Ferrosan	Oxadiazolylimidazobenzodiazepine, compositions, and method
US4745112A (en) *	1985-05-17	1988-05-17	A/S Ferrosan	Oxadiazolylimidazobenzodiazepine, compositions, and method III
CA1297099C (en) *	1985-10-17	1992-03-10	Frank Watjen	Quinazoline compounds and their preparation and use
DK174086D0 (da) *	1986-04-16	1986-04-16	Ferrosan As	Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
DK522187D0 (da) *	1987-10-06	1987-10-06	Ferrosan As	Imidozothienopyrimidiner, deres fremstilling og anvendelse
GB8823475D0 (en) *	1988-10-06	1988-11-16	Merck Sharp & Dohme	Chemical compounds
CA2143246C (en) *	1994-03-16	2000-08-22	Thierry Godel	Imidazodiazepines
FI101305B1 (fi) *	1996-03-18	1998-05-29	Map Medical Technologies Oy	Radiofarmaseuttisena aineena käyttökelpoiset radiojodatut bentsodiatsepiini-johdannaiset ja niiden käyttö diagnostiikassa
US20090054412A1 (en) *	2007-08-20	2009-02-26	John Alan Kemp	Treatment of Sleep Disorders
WO2009024325A2 (en) *	2007-08-20	2009-02-26	Evotec Neurosciences Gmbh	Treatment of sleep disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4031029A (en) *	1975-07-02	1977-06-21	General Electric Company	Process for producing uranium oxide rich compositions from uranium hexafluoride using fluid injection into the reaction zone
CA1143728A (en) *	1979-10-04	1983-03-29	Max Gerecke	Imidazodiazepine derivatives
JPS57123180A (en) *	1980-12-17	1982-07-31	Schering Ag	3-substituted beta-carboline, manufacture and psychotropic drug containing same
DK151808C (da) *	1982-11-16	1988-06-20	Ferrosan As	Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater
FI850191A7 (fi) *	1984-01-19	1985-07-20	Hoffmann La Roche	Imidatsodiatsepiini-johdannaisia.
AU587802B2 (en) *	1985-03-08	1989-08-31	Ferrosan A/S	Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds
US4622320A (en) *	1985-05-17	1986-11-11	As Ferrosan	Oxadiazolylimidazobenzodiazepine, compositions, and method
CA1297099C (en) *	1985-10-17	1992-03-10	Frank Watjen	Quinazoline compounds and their preparation and use
DK174086D0 (da) *	1986-04-16	1986-04-16	Ferrosan As	Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme

1986
- 1986-01-06 US US06/816,732 patent/US4622320A/en not_active Expired - Fee Related
- 1986-01-06 US US06/816,731 patent/US4622321A/en not_active Expired - Fee Related
- 1986-03-06 AT AT86102951T patent/ATE35266T1/de not_active IP Right Cessation
- 1986-03-06 DE DE8686102951T patent/DE3660331D1/de not_active Expired
- 1986-03-06 EP EP86102951A patent/EP0201678B1/de not_active Expired
- 1986-03-06 DE DE198686102951T patent/DE201678T1/de active Pending
- 1986-04-30 CA CA000507956A patent/CA1256864A/en not_active Expired
- 1986-04-30 CA CA000507955A patent/CA1256863A/en not_active Expired
- 1986-05-14 GR GR861260A patent/GR861260B/el unknown
- 1986-05-14 AU AU57429/86A patent/AU590273B2/en not_active Ceased
- 1986-05-15 IL IL78790A patent/IL78790A/xx not_active IP Right Cessation
- 1986-05-16 IE IE130686A patent/IE59494B1/en not_active IP Right Cessation
- 1986-05-16 DK DK231686A patent/DK157194C/da not_active IP Right Cessation
- 1986-05-16 NZ NZ216202A patent/NZ216202A/xx unknown
- 1986-05-16 ES ES555035A patent/ES8707205A1/es not_active Expired
- 1986-05-16 PT PT82594A patent/PT82594B/pt not_active IP Right Cessation
- 1986-05-16 FI FI862061A patent/FI82049C/fi not_active IP Right Cessation
- 1986-05-16 NO NO861954A patent/NO163228C/no unknown
1988
- 1988-02-08 DK DK063288A patent/DK160097C/da not_active IP Right Cessation
1989
- 1989-03-17 JP JP1065783A patent/JPH01279877A/ja active Pending
- 1989-08-04 AU AU39333/89A patent/AU614407B2/en not_active Ceased

Also Published As

Publication number	Publication date
EP0201678A1 (de)	1986-11-20
IL78790A0 (en)	1986-08-31
CA1256863A (en)	1989-07-04
DE201678T1 (de)	1987-02-26
DE3660331D1 (en)	1988-07-28
DK63288D0 (da)	1988-02-08
GR861260B (en)	1986-09-10
FI82049B (fi)	1990-09-28
ES8707205A1 (es)	1987-07-16
NZ216202A (en)	1989-08-29
AU614407B2 (en)	1991-08-29
ATE35266T1 (de)	1988-07-15
US4622320A (en)	1986-11-11
EP0201678B1 (de)	1988-06-22
CA1256864A (en)	1989-07-04
DK160097C (da)	1991-06-24
NO163228B (no)	1990-01-15
NO163228C (no)	1990-04-25
DK63288A (da)	1988-02-08
NO861954L (no)	1986-11-18
JPH01279877A (ja)	1989-11-10
PT82594B (pt)	1988-03-03
FI862061L (fi)	1986-11-18
FI82049C (fi)	1991-01-10
US4622321A (en)	1986-11-11
DK231686A (da)	1986-11-18
IE861306L (en)	1986-11-17
DK160097B (da)	1991-01-28
AU590273B2 (en)	1989-11-02
FI862061A0 (fi)	1986-05-16
AU5742986A (en)	1986-11-20
ES555035A0 (es)	1987-07-16
AU3933389A (en)	1989-11-23
DK157194B (da)	1989-11-20
DK231686D0 (da)	1986-05-16
PT82594A (en)	1986-06-01
IL78790A (en)	1990-01-18
DK157194C (da)	1990-04-23

Legal Events

Date	Code	Title	Description
1997-03-26	MM4A	Patent lapsed

Publication	Publication Date	Title
US4774245A (en)	1988-09-27	Imidazoquinoxaline compounds
EP0241682B1 (de)	1990-11-28	Benzodiazepinderivate und ihre Herstellung und Verwendung
US4968682A (en)	1990-11-06	Imidazoquinoxaline compounds and their preparation and use
EP0201678B1 (de)	1988-06-22	3-(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepin, Verfahren zu seiner Herstellung und pharmazeutische Zubereitungen
US4771051A (en)	1988-09-13	3-substituted-4,5-dihydro-5-oxo imidazoquinazolines, their preparation, and their use in treating benzodiazepin receptor-related ailments
EP0226282B1 (de)	1989-07-05	Heterocyclische Verbindungen und ihre Herstellung und Verwendung
US5034530A (en)	1991-07-23	Imidazoquinoxaline compounds and their preparation and use
US5075304A (en)	1991-12-24	Imidazoquinoxaline compounds and their preparation and use
EP0202441B1 (de)	1988-11-17	Oxadiazolylimidazobenzodiazepine, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen
US5276028A (en)	1994-01-04	Imidazoquinoxaline compounds
US4745112A (en)	1988-05-17	Oxadiazolylimidazobenzodiazepine, compositions, and method III
US5100895A (en)	1992-03-31	Heterocyclic compounds and their preparation and use
WO1992000298A1 (en)	1992-01-09	Heterocyclic compounds and their preparation and use
AU594676B2 (en)	1990-03-15	Oxadiazolyl imidazobenaodiazepine compound, pharmaceutical composition containing said compound, method of preparing said compound and method of treating a central nervous system ailment
JPS61263979A (ja)	1986-11-21	オキサジアゾリルイミダゾベンゾジアゼピン、並びに抗けいれん及び抗不安剤