IE914347A1 - Fusion polypeptides - Google Patents
Fusion polypeptidesInfo
- Publication number
- IE914347A1 IE914347A1 IE434791A IE434791A IE914347A1 IE 914347 A1 IE914347 A1 IE 914347A1 IE 434791 A IE434791 A IE 434791A IE 434791 A IE434791 A IE 434791A IE 914347 A1 IE914347 A1 IE 914347A1
- Authority
- IE
- Ireland
- Prior art keywords
- ala
- seq
- tyr
- leu
- pro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57509—Corticotropin releasing factor [CRF] (Urotensin)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57536—Endothelin, vasoactive intestinal contractor [VIC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Vascular Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62672790A | 1990-12-13 | 1990-12-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IE914347A1 true IE914347A1 (en) | 1992-06-17 |
Family
ID=24511577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE434791A IE914347A1 (en) | 1990-12-13 | 1991-12-13 | Fusion polypeptides |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0561971A1 (fr) |
| JP (1) | JPH06503473A (fr) |
| AU (1) | AU662508B2 (fr) |
| CA (1) | CA2094512A1 (fr) |
| CZ (1) | CZ109393A3 (fr) |
| FI (1) | FI932680A0 (fr) |
| HU (1) | HUT69963A (fr) |
| IE (1) | IE914347A1 (fr) |
| NO (1) | NO932148L (fr) |
| RU (1) | RU2114119C1 (fr) |
| SK (1) | SK60893A3 (fr) |
| TW (1) | TW213923B (fr) |
| WO (1) | WO1992010576A1 (fr) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9906715D0 (en) * | 1999-03-23 | 1999-05-19 | Ferring Bv | Compositions for promoting growth |
| US20050272652A1 (en) | 1999-03-29 | 2005-12-08 | Gault Victor A | Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity |
| EP1052286A3 (fr) * | 1999-04-12 | 2001-07-25 | Pfizer Products Inc. | Preparations contenant l'hormone de croissance GH et l'hormone libérant l'hormone de croissance GHRH |
| US6759393B1 (en) | 1999-04-12 | 2004-07-06 | Pfizer Inc. | Growth hormone and growth hormone releasing hormone compositions |
| MXPA02005014A (es) | 1999-11-19 | 2003-02-27 | Transkaryotic Therapies Inc | Constructo de acido nucleico para produccion optimizada de productos. |
| GB0010188D0 (en) * | 2000-04-26 | 2000-06-14 | Ferring Bv | Inhibitors of dipeptidyl peptidase IV |
| EP1205551A1 (fr) * | 2000-11-09 | 2002-05-15 | Pfizer Products Inc. | Préparations contenant l'hormone de croissance GH et l'hormone libérant l'hormone de croissance GHRH |
| WO2002079415A2 (fr) * | 2001-03-30 | 2002-10-10 | Lexigen Pharmaceuticals Corp. | Reduction de l'immunogenicite de proteines de fusion |
| DK1454138T3 (da) * | 2001-12-04 | 2012-02-13 | Merck Patent Gmbh | Immunocytokiner med moduleret selektivitet |
| GB2384001B (en) * | 2001-12-14 | 2004-02-04 | Asterion Ltd | Chimeric growth hormone-growth hormone receptor proteins |
| EP2298337B1 (fr) | 2003-12-09 | 2017-02-22 | Novo Nordisk A/S | Régulation des préférences alimentaires en utilisant des agonistes du GLP-1 |
| EP1758575A1 (fr) | 2004-06-11 | 2007-03-07 | Novo Nordisk A/S | Remede contre l'obesite induite par les medicaments au moyen d'agonistes glp-1 |
| KR20070115947A (ko) | 2005-02-11 | 2007-12-06 | 아밀린 파마슈티칼스, 인크. | 선택가능한 특성들을 가지는 ｇｉｐ 유사체 및 하이브리드폴리펩타이드 |
| US8263545B2 (en) | 2005-02-11 | 2012-09-11 | Amylin Pharmaceuticals, Inc. | GIP analog and hybrid polypeptides with selectable properties |
| US7855279B2 (en) | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
| AU2007223855B2 (en) † | 2006-03-06 | 2013-05-16 | Amunix Operating Inc. | Unstructured recombinant polymers and uses thereof |
| US8497240B2 (en) | 2006-08-17 | 2013-07-30 | Amylin Pharmaceuticals, Llc | DPP-IV resistant GIP hybrid polypeptides with selectable properties |
| ES2610356T3 (es) | 2009-02-03 | 2017-04-27 | Amunix Operating Inc. | Polipéptidos recombinantes extendidos y composiciones que comprenden los mismos |
| CA2771999A1 (fr) | 2009-08-24 | 2011-03-10 | Amunix Operating Inc. | Compositions de facteurs de coagulation vii et procedes de preparation et d'utilisation de celles-ci |
| EP2573103B1 (fr) * | 2010-01-29 | 2017-07-05 | Archer-Daniels-Midland Company | Domaines peptidiques se liant à de petites molécules d'importance industrielle |
| EP2822577B1 (fr) | 2012-02-15 | 2019-02-06 | Bioverativ Therapeutics Inc. | Protéines de facteur viii de recombinaison |
| JP6256882B2 (ja) | 2012-02-15 | 2018-01-10 | アムニクス オペレーティング インコーポレイテッド | 第ｖｉｉｉ因子組成物、ならびに組成物の作製方法および用途 |
| TW202003554A (zh) | 2013-08-14 | 2020-01-16 | 美商百歐維拉提夫治療公司 | 因子ｖｉｉｉ－ｘｔｅｎ融合物及其用途 |
| EA201890423A1 (ru) | 2015-08-03 | 2018-07-31 | Биовератив Терапьютикс Инк. | Слитые белки фактора ix, способы их получения и применения |
| MX2019006444A (es) | 2016-12-02 | 2019-10-30 | Bioverativ Therapeutics Inc | Métodos de tratamiento de artropatía hemofílica utilizando factores de coagulación quiméricos. |
| SG11201912433YA (en) * | 2017-06-29 | 2020-01-30 | Ureka Sarl | Pro-drug peptide with improved pharmaceutical properties |
| PL3793588T3 (pl) | 2018-05-18 | 2025-09-01 | Bioverativ Therapeutics Inc. | Sposoby leczenia hemofilii a |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4703004A (en) * | 1984-01-24 | 1987-10-27 | Immunex Corporation | Synthesis of protein with an identification peptide |
| US4569794A (en) * | 1984-12-05 | 1986-02-11 | Eli Lilly And Company | Process for purifying proteins and compounds useful in such process |
| US4734399A (en) * | 1985-08-06 | 1988-03-29 | Hoffmann-La Roche Inc. | Growth hormone releasing factor analogs |
| CA1340522C (fr) * | 1987-03-10 | 1999-05-04 | Heinz Dobeli | Proteins hybrides renfermant des histidines voisines pour une purification amelioree |
| ATE113965T1 (de) * | 1989-06-16 | 1994-11-15 | Upjohn Co | Stabilisierte, starke grf-analoga. |
| DE69120409T2 (de) * | 1990-04-09 | 1996-11-28 | Upjohn Co | Verfahren zur reinigung von rekombinanten proteinen und dafür nützliche produkte |
-
1991
- 1991-12-12 HU HU9301705A patent/HUT69963A/hu unknown
- 1991-12-12 WO PCT/US1991/009152 patent/WO1992010576A1/fr not_active Ceased
- 1991-12-12 SK SK60893A patent/SK60893A3/sk unknown
- 1991-12-12 EP EP92901817A patent/EP0561971A1/fr not_active Withdrawn
- 1991-12-12 JP JP4501996A patent/JPH06503473A/ja active Pending
- 1991-12-12 AU AU91165/91A patent/AU662508B2/en not_active Ceased
- 1991-12-12 CZ CS931093A patent/CZ109393A3/cs unknown
- 1991-12-12 FI FI932680A patent/FI932680A0/fi not_active Application Discontinuation
- 1991-12-12 CA CA002094512A patent/CA2094512A1/fr not_active Abandoned
- 1991-12-12 RU RU93045577A patent/RU2114119C1/ru active
- 1991-12-13 IE IE434791A patent/IE914347A1/en not_active Application Discontinuation
- 1991-12-17 TW TW080109839A patent/TW213923B/zh active
-
1993
- 1993-06-11 NO NO93932148A patent/NO932148L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CZ109393A3 (en) | 1994-01-19 |
| HU9301705D0 (en) | 1993-10-28 |
| EP0561971A1 (fr) | 1993-09-29 |
| FI932680L (fi) | 1993-06-11 |
| NO932148L (no) | 1993-08-09 |
| NO932148D0 (no) | 1993-06-11 |
| HUT69963A (en) | 1995-09-28 |
| WO1992010576A1 (fr) | 1992-06-25 |
| RU2114119C1 (ru) | 1998-06-27 |
| FI932680A7 (fi) | 1993-06-11 |
| FI932680A0 (fi) | 1993-06-11 |
| TW213923B (fr) | 1993-10-01 |
| JPH06503473A (ja) | 1994-04-21 |
| AU9116591A (en) | 1992-07-08 |
| CA2094512A1 (fr) | 1992-06-14 |
| AU662508B2 (en) | 1995-09-07 |
| SK60893A3 (en) | 1993-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC9A | Application refused sect. 31(1) |