IL100061A0 - Tricyclic compounds,their preparation and pharmaceutical compositions containing them - Google Patents

Tricyclic compounds,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL100061A0
IL100061A0 IL100061A IL10006191A IL100061A0 IL 100061 A0 IL100061 A0 IL 100061A0 IL 100061 A IL100061 A IL 100061A IL 10006191 A IL10006191 A IL 10006191A IL 100061 A0 IL100061 A0 IL 100061A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
tricyclic compounds
tricyclic
Prior art date
Application number
IL100061A
Other languages
English (en)
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of IL100061A0 publication Critical patent/IL100061A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL100061A 1990-11-16 1991-11-15 Tricyclic compounds,their preparation and pharmaceutical compositions containing them IL100061A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/614,326 US5189041A (en) 1990-11-16 1990-11-16 Tricyclic 5-ht3 receptor antagonists

Publications (1)

Publication Number Publication Date
IL100061A0 true IL100061A0 (en) 1992-08-18

Family

ID=24460766

Family Applications (1)

Application Number Title Priority Date Filing Date
IL100061A IL100061A0 (en) 1990-11-16 1991-11-15 Tricyclic compounds,their preparation and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US5189041A (fr)
EP (1) EP0485962A3 (fr)
JP (1) JPH04283587A (fr)
KR (1) KR920009828A (fr)
AU (1) AU8785291A (fr)
CA (1) CA2055680A1 (fr)
FI (1) FI915400A7 (fr)
HU (1) HUT59406A (fr)
IE (1) IE913987A1 (fr)
IL (1) IL100061A0 (fr)
IT (1) IT1250049B (fr)
MX (1) MX9102076A (fr)
NO (1) NO914490L (fr)
PL (1) PL292419A1 (fr)
PT (1) PT99518A (fr)
TW (1) TW208007B (fr)
ZA (1) ZA919078B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL166267B1 (pl) * 1989-11-28 1995-04-28 Syntex Inc Sposób wytwarzania nowych zwiazków trójpierscieniowych PL PL PL PL
WO1993018036A1 (fr) * 1992-03-12 1993-09-16 Smithkline Beecham Plc Derives condenses d'indoles en tant qu'antagonistes du recepteur 5ht¿4?
US5852014A (en) * 1992-03-12 1998-12-22 Smithkline Beecham P.L.C. Condensed indole derivatives as 5HT4 -receptor antagonists
MX9305947A (es) * 1992-09-29 1994-06-30 Smithkline Beecham Plc Compuestos antagonistas del receptor 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
ATE161819T1 (de) * 1993-04-27 1998-01-15 Solvay Fluor & Derivate Verfahren zur herstellung von carbonsäureestern aus carbonsäurehalogeniden und alkoholen
US6489355B2 (en) * 1993-12-01 2002-12-03 Eli Lilly And Company Methods of inhibiting the effects of amyloidogenic proteins
US5723103A (en) * 1994-12-09 1998-03-03 Vanderbilt University Substituted benzamides and radioligand analogs and methods of use
IT1303123B1 (it) 1998-10-13 2000-10-30 Rotta Research Lab Derivati basici di benz(e)isoindol-1-oni e pirrolo(3,4-c)chinolin-1-oni ad attivita' 5ht3 antagonista, loro preparazione ed
WO2001058869A2 (fr) * 2000-02-11 2001-08-16 Bristol-Myers Squibb Company Modulateurs de recepteurs aux cannabinoides, leurs procedes de preparation et utilisations de modulateurs de recepteurs aux cannabinoides pour le traitement de maladies respiratoires et non respiratoires
EP1284732A2 (fr) * 2000-05-18 2003-02-26 Glaxo Group Limited Methode de traitement de la dyspepsie fonctionnelle
AR036040A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
AR036041A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
MXPA04004373A (es) 2001-11-09 2004-08-11 Upjohn Co Compuestos heterociclicos condensados con fenilo azabiciclo para el tratamiento de enfermedades.
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
DE10234424A1 (de) 2002-07-29 2004-02-12 Bayer Ag Benzothiophen-, Benzofuran- und Indolharnstoffe
MY143789A (en) 2003-02-18 2011-07-15 Helsinn Healthcare Sa Use of palonosetron treating post- operative nausea and vomiting
ITMI20031467A1 (it) * 2003-07-18 2005-01-19 Acraf Farmaco attivo nel dolore neuropatico
LT2889033T (lt) 2008-11-19 2018-07-10 Forum Pharmaceuticals Inc. Šizofrenijos negatyvių simptomų gydymas (r)-7-chlor-n-(chinuklidin-3-il)benzo[b]tiofen-2-karboksamidu ir jo farmaciniu požiūriu priimtinomis druskomis
US9145396B2 (en) * 2008-12-01 2015-09-29 Targacept, Inc. Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3ylvinyl)pyrimidine
PE20170923A1 (es) 2010-05-17 2017-07-12 Forum Pharmaceuticals Inc Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida monohidratado
EP3461481A1 (fr) 2012-05-08 2019-04-03 Forum Pharmaceuticals Inc. Procédés de maintien, de traitement ou d'amélioration de la fonction cognitive

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2121394A1 (fr) * 1971-01-08 1972-08-25 Anvar Procédé d'obtention de dérivés d'acides indole carboxyliques et produits préparables par ce procédé.
JPS5337696A (en) * 1976-08-26 1978-04-06 Omnium Chimique Sa Hexahydrocantinonee6 derivative
FR2475394A1 (fr) * 1980-02-12 1981-08-14 Synthelabo Compositions pharmaceutiques contenant l'hexahydro-1, 2, 3, 3a, 4, 5, 6h indolo (3, 2, 1 - d. e) (1, 5) naphtyridinone - 6
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
GB8623142D0 (en) * 1986-09-26 1986-10-29 Beecham Group Plc Compounds
US4948803A (en) * 1986-11-21 1990-08-14 Glaxo Group Limited Medicaments for treatment on prevention of withdrawal syndrome
EP0306323B1 (fr) * 1987-09-03 1994-09-21 Glaxo Group Limited Dérivés de lactames
DE3810552A1 (de) * 1988-03-29 1989-10-19 Sandoz Ag Ester und amide von indol-, benzo(b)thiopen-, benzo(b)furancarbonsaeuren oder 4-amino-2-methoxy-benzolsaeuren mit n-heterocyclischen oder n-heterobicyclischen alkoholen oder aminen, verfahren zu deren herstellung sie enthaltende pharmazeutische zusammensetzungen sowie applikator zur verabreichung derselben
JPH02167280A (ja) * 1988-08-15 1990-06-27 Glaxo Group Ltd ラクタム誘導体
EP0377238A1 (fr) * 1988-12-22 1990-07-11 Duphar International Research B.V Indolo(3,2-c)-lactames annelés
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
EP0392663A1 (fr) * 1989-03-13 1990-10-17 Ono Pharmaceutical Co., Ltd. Un dérivé de carboline comme antagoniste du récepteur 5-HT3
JPH02290878A (ja) * 1989-04-28 1990-11-30 Ono Pharmaceut Co Ltd ベンゾチエノ（フロ）ピリジン誘導体

Also Published As

Publication number Publication date
IE913987A1 (en) 1992-05-20
ITTO910865A1 (it) 1993-05-12
EP0485962A3 (en) 1992-07-29
TW208007B (fr) 1993-06-21
CA2055680A1 (fr) 1992-05-17
MX9102076A (es) 1992-07-08
ITTO910865A0 (it) 1991-11-12
NO914490L (no) 1992-05-18
ZA919078B (en) 1993-05-17
AU8785291A (en) 1992-05-21
NO914490D0 (no) 1991-11-15
IT1250049B (it) 1995-03-30
HUT59406A (en) 1992-05-28
FI915400A0 (fi) 1991-11-15
PT99518A (pt) 1992-09-30
JPH04283587A (ja) 1992-10-08
EP0485962A2 (fr) 1992-05-20
KR920009828A (ko) 1992-06-25
FI915400A7 (fi) 1992-05-17
HU913579D0 (en) 1992-01-28
US5189041A (en) 1993-02-23
PL292419A1 (en) 1993-04-05

Similar Documents

Publication Publication Date Title
IL99225A0 (en) 3-amidopyrazole derivatives,their preparation and pharmaceutical compositions containing them
ZA915759B (en) Substituted bicyclic bis-aryl compounds,their preparation and pharmaceutical compositions containing them
IL98176A0 (en) Bicyclic 1-aza-cycloalkanes,their preparation and pharmaceutical compositions containing them
IL102638A0 (en) Heterocyclic compounds,their preparation and pharmaceutical compositions containing them
IL103053A0 (en) Heterocyclic compounds,their preparation and pharmaceutical compositions containing them
IL101763A0 (en) Dialkylenepiperidino compounds and their enantiomers,their preparation and pharmaceutical compositions containing them
IL101864A0 (en) Thiopyranopyrrole derivatives,their preparation and pharmaceutical compositions containing them
IL100262A0 (en) Alpha-oxoacetamide derivatives,their preparation and pharmaceutical compositions containing them
IL100229A0 (en) N,o-sulphated heparosans,their preparation and pharmaceutical compositions containing them
IL101380A0 (en) Bis-naphthalimides,their preparation and pharmaceutical compositions containing them
IL97050A0 (en) 4-isoxazolecarboxamide derivatives,pharmaceutical compositions containing them and their preparation
IL91361A0 (en) Tricyclic compounds,processes for the preparation thereof and pharmaceutical compositions containing the same
IL100061A0 (en) Tricyclic compounds,their preparation and pharmaceutical compositions containing them
IL98542A0 (en) Benzoquinazoline derivatives,their preparation and pharmaceutical compositions containing them
IL98756A0 (en) Pharmaceutical compositions containing benzeneacetamid derivatives,certain such novel compounds and their preparation
IL98499A0 (en) Aminobenzodiazepines,their preparation and pharmaceutical compositions containing them
IL100364A0 (en) Benzodiazepinones,their preparation and pharmaceutical compositions containing them
IL103160A0 (en) Quinoxaline compounds,their preparation and pharmaceutical compositions containing them
IL103502A0 (en) Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL104099A0 (en) Imidazoquinazoline compounds,their preparation and pharmaceutical compositions containing them
IL98223A0 (en) Pharmaceutical compositions containing fluorene derivatives,some such novel compounds and their preparation
IL98691A0 (en) Tricyclic compounds containing heteroatoms,their preparation and pharmaceutical compositions containing them
IL102500A0 (en) 3-deoxy-mannosamine derivatives,their preparation and pharmaceutical compositions containing them
IL90389A0 (en) Tricyclic 3-oxo-propanenitrile derivatives,their preparation and pharmaceutical compositions containing them
IL104042A0 (en) Substituted diphenylsulfides,their preparation and pharmaceutical compositions containing them