NO914490L - Analogifremgangsmaate for fremstilling av terapeutisk virksomme tricykliske forbindelser - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk virksomme tricykliske forbindelser

Info

Publication number
NO914490L
NO914490L NO91914490A NO914490A NO914490L NO 914490 L NO914490 L NO 914490L NO 91914490 A NO91914490 A NO 91914490A NO 914490 A NO914490 A NO 914490A NO 914490 L NO914490 L NO 914490L
Authority
NO
Norway
Prior art keywords
preparation
therapeutically effective
tricyclic compounds
analogy procedure
effective tricyclic
Prior art date
Application number
NO91914490A
Other languages
English (en)
Norwegian (no)
Other versions
NO914490D0 (no
Inventor
Jacob Berger
Robin D Clark
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of NO914490D0 publication Critical patent/NO914490D0/no
Publication of NO914490L publication Critical patent/NO914490L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO91914490A 1990-11-16 1991-11-15 Analogifremgangsmaate for fremstilling av terapeutisk virksomme tricykliske forbindelser NO914490L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/614,326 US5189041A (en) 1990-11-16 1990-11-16 Tricyclic 5-ht3 receptor antagonists

Publications (2)

Publication Number Publication Date
NO914490D0 NO914490D0 (no) 1991-11-15
NO914490L true NO914490L (no) 1992-05-18

Family

ID=24460766

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91914490A NO914490L (no) 1990-11-16 1991-11-15 Analogifremgangsmaate for fremstilling av terapeutisk virksomme tricykliske forbindelser

Country Status (17)

Country Link
US (1) US5189041A (fr)
EP (1) EP0485962A3 (fr)
JP (1) JPH04283587A (fr)
KR (1) KR920009828A (fr)
AU (1) AU8785291A (fr)
CA (1) CA2055680A1 (fr)
FI (1) FI915400A7 (fr)
HU (1) HUT59406A (fr)
IE (1) IE913987A1 (fr)
IL (1) IL100061A0 (fr)
IT (1) IT1250049B (fr)
MX (1) MX9102076A (fr)
NO (1) NO914490L (fr)
PL (1) PL292419A1 (fr)
PT (1) PT99518A (fr)
TW (1) TW208007B (fr)
ZA (1) ZA919078B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ236225A (en) * 1989-11-28 1992-09-25 Syntex Inc Azabicyclic-substituted isoquinoline derivatives, intermediates and pharmaceutical compositions
US5852014A (en) * 1992-03-12 1998-12-22 Smithkline Beecham P.L.C. Condensed indole derivatives as 5HT4 -receptor antagonists
ATE266033T1 (de) * 1992-03-12 2004-05-15 Smithkline Beecham Plc N- (1-nbutyl-4-piperidyl)methyl -3,4-dihydro-2h- 1,3 oxazino 3,2-a indol-10-carboxamid oder ein pharmazeutisch annehmbares salz davon
MX9305947A (es) * 1992-09-29 1994-06-30 Smithkline Beecham Plc Compuestos antagonistas del receptor 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
EP0623582B1 (fr) * 1993-04-27 1998-01-07 Solvay Fluor und Derivate GmbH Procédé de préparation d'esters d'acides carboxyliques à partir d'halogénures d'acides carboxyliques et d'alcools
US6489355B2 (en) * 1993-12-01 2002-12-03 Eli Lilly And Company Methods of inhibiting the effects of amyloidogenic proteins
US5723103A (en) * 1994-12-09 1998-03-03 Vanderbilt University Substituted benzamides and radioligand analogs and methods of use
IT1303123B1 (it) * 1998-10-13 2000-10-30 Rotta Research Lab Derivati basici di benz(e)isoindol-1-oni e pirrolo(3,4-c)chinolin-1-oni ad attivita' 5ht3 antagonista, loro preparazione ed
AU2001234958A1 (en) * 2000-02-11 2001-08-20 Bristol-Myers Squibb Company Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators for treating respiratory and non-respiratory diseases
WO2001087305A2 (fr) * 2000-05-18 2001-11-22 Glaxo Group Limited Methode de traitement de la dyspepsie fonctionnelle
AR036040A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
AR036041A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
US6951868B2 (en) 2001-11-09 2005-10-04 Pfizer Inc. Azabicyclic-phenyl-fused-heterocyclic compounds for treatment of disease
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
DE10234424A1 (de) 2002-07-29 2004-02-12 Bayer Ag Benzothiophen-, Benzofuran- und Indolharnstoffe
TWI355936B (en) 2003-02-18 2012-01-11 Helsinn Healthcare Sa Uses of palonosetron hydrochloride
ITMI20031467A1 (it) * 2003-07-18 2005-01-19 Acraf Farmaco attivo nel dolore neuropatico
CA2894860C (fr) 2008-11-19 2018-11-06 Gerhard Koenig Traitement de troubles cognitifs par la (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide et les sels de qualite pharmaceutique de celle-ci
US9145396B2 (en) 2008-12-01 2015-09-29 Targacept, Inc. Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3ylvinyl)pyrimidine
MX357676B (es) 2010-05-17 2018-07-18 Forum Pharmaceuticals Inc Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin- 3-il)benzo[b]tiofeno-2-carboxamida monohidratado.
EP3666272A1 (fr) 2012-05-08 2020-06-17 Forum Pharmaceuticals Inc. Utilisation de l'encénicline dans le traitement de la déficience cognitive, de la maladie d'alzheimer, du déficit de mémoire

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2121394A1 (fr) * 1971-01-08 1972-08-25 Anvar Procédé d'obtention de dérivés d'acides indole carboxyliques et produits préparables par ce procédé.
JPS5337696A (en) * 1976-08-26 1978-04-06 Omnium Chimique Sa Hexahydrocantinonee6 derivative
FR2475394A1 (fr) * 1980-02-12 1981-08-14 Synthelabo Compositions pharmaceutiques contenant l'hexahydro-1, 2, 3, 3a, 4, 5, 6h indolo (3, 2, 1 - d. e) (1, 5) naphtyridinone - 6
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
GB8623142D0 (en) * 1986-09-26 1986-10-29 Beecham Group Plc Compounds
WO1988003801A1 (fr) * 1986-11-21 1988-06-02 Glaxo Group Limited Medicaments pour le traitement ou la prevention d'un syndrome de reaction a la privation
NZ226032A (en) * 1987-09-03 1991-12-23 Glaxo Group Ltd 2-(imidazolylmethyl)-pyrido or-azepino(4,3-b)indole-1(2h)-one derivatives; preparatory processes and pharmaceutical compositions
DE3810552A1 (de) * 1988-03-29 1989-10-19 Sandoz Ag Ester und amide von indol-, benzo(b)thiopen-, benzo(b)furancarbonsaeuren oder 4-amino-2-methoxy-benzolsaeuren mit n-heterocyclischen oder n-heterobicyclischen alkoholen oder aminen, verfahren zu deren herstellung sie enthaltende pharmazeutische zusammensetzungen sowie applikator zur verabreichung derselben
JPH02167280A (ja) * 1988-08-15 1990-06-27 Glaxo Group Ltd ラクタム誘導体
EP0377238A1 (fr) * 1988-12-22 1990-07-11 Duphar International Research B.V Indolo(3,2-c)-lactames annelés
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
EP0392663A1 (fr) * 1989-03-13 1990-10-17 Ono Pharmaceutical Co., Ltd. Un dérivé de carboline comme antagoniste du récepteur 5-HT3
JPH02290878A (ja) * 1989-04-28 1990-11-30 Ono Pharmaceut Co Ltd ベンゾチエノ（フロ）ピリジン誘導体

Also Published As

Publication number Publication date
TW208007B (fr) 1993-06-21
ITTO910865A1 (it) 1993-05-12
IE913987A1 (en) 1992-05-20
IT1250049B (it) 1995-03-30
ITTO910865A0 (it) 1991-11-12
MX9102076A (es) 1992-07-08
IL100061A0 (en) 1992-08-18
EP0485962A2 (fr) 1992-05-20
HUT59406A (en) 1992-05-28
PL292419A1 (en) 1993-04-05
NO914490D0 (no) 1991-11-15
EP0485962A3 (en) 1992-07-29
AU8785291A (en) 1992-05-21
HU913579D0 (en) 1992-01-28
CA2055680A1 (fr) 1992-05-17
ZA919078B (en) 1993-05-17
FI915400A0 (fi) 1991-11-15
US5189041A (en) 1993-02-23
FI915400A7 (fi) 1992-05-17
PT99518A (pt) 1992-09-30
JPH04283587A (ja) 1992-10-08
KR920009828A (ko) 1992-06-25

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