IL101042A - 3-piperidinylmethyl-carboxylate substituted indoles their preparation and pharmaceutical compositions containing them - Google Patents

3-piperidinylmethyl-carboxylate substituted indoles their preparation and pharmaceutical compositions containing them

Info

Publication number
IL101042A
IL101042A IL10104292A IL10104292A IL101042A IL 101042 A IL101042 A IL 101042A IL 10104292 A IL10104292 A IL 10104292A IL 10104292 A IL10104292 A IL 10104292A IL 101042 A IL101042 A IL 101042A
Authority
IL
Israel
Prior art keywords
methyl
compound
indole
carboxylate
group
Prior art date
Application number
IL10104292A
Other languages
English (en)
Other versions
IL101042A0 (en
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IL101042A0 publication Critical patent/IL101042A0/xx
Publication of IL101042A publication Critical patent/IL101042A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL10104292A 1991-02-25 1992-02-24 3-piperidinylmethyl-carboxylate substituted indoles their preparation and pharmaceutical compositions containing them IL101042A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919103862A GB9103862D0 (en) 1991-02-25 1991-02-25 Chemical compounds
APAP/P/1992/000417A AP295A (en) 1991-02-25 1992-08-17 3-Piperidinylmethylcarboxylate substituted indoles.
CN92110050A CN1083059A (zh) 1991-02-25 1992-08-24 3-哌啶甲基羧酸酯取代的吲哚

Publications (2)

Publication Number Publication Date
IL101042A0 IL101042A0 (en) 1992-11-15
IL101042A true IL101042A (en) 1996-06-18

Family

ID=36790873

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10104292A IL101042A (en) 1991-02-25 1992-02-24 3-piperidinylmethyl-carboxylate substituted indoles their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
EP (1) EP0501322B1 (de)
JP (1) JPH06505238A (de)
CN (1) CN1083059A (de)
AP (1) AP295A (de)
AT (1) ATE142205T1 (de)
AU (1) AU645402B2 (de)
CA (1) CA2105179A1 (de)
DE (1) DE69213276T2 (de)
ES (1) ES2091963T3 (de)
FI (1) FI933697A0 (de)
GB (1) GB9103862D0 (de)
HU (1) HUT65486A (de)
IE (1) IE920567A1 (de)
IL (1) IL101042A (de)
MX (1) MX9200762A (de)
NO (1) NO933015D0 (de)
NZ (1) NZ241704A (de)
WO (1) WO1992014727A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020128172A1 (en) 1991-12-21 2002-09-12 Smithkline Beecham Plc Use of 5-HT4 modulators for the manufacture of a medicament for the treatment of the bladder diseases
ATE170747T1 (de) * 1991-12-21 1998-09-15 Smithkline Beecham Plc Verwendung von 5-ht4 - antagonisten zur herstellung eines arzneimittels zur behandlung von harninkontinenz
ATE266033T1 (de) * 1992-03-12 2004-05-15 Smithkline Beecham Plc N- (1-nbutyl-4-piperidyl)methyl -3,4-dihydro-2h- 1,3 oxazino 3,2-a indol-10-carboxamid oder ein pharmazeutisch annehmbares salz davon
US5852014A (en) * 1992-03-12 1998-12-22 Smithkline Beecham P.L.C. Condensed indole derivatives as 5HT4 -receptor antagonists
EP0641198A1 (de) * 1992-05-23 1995-03-08 Smithkline Beecham Plc Arzneimittel zur behandlung von angstzuständen
JPH07508276A (ja) * 1992-06-27 1995-09-14 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ５−ｈｔ↓４受容体アンタゴニスト含有医薬品
MX9305947A (es) * 1992-09-29 1994-06-30 Smithkline Beecham Plc Compuestos antagonistas del receptor 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
GB9221468D0 (en) * 1992-10-13 1992-11-25 Smithkline Beecham Plc Pharmaceuticals
MX9306311A (es) * 1992-10-13 1994-04-29 Smithkline Beecham Plc Compuestos antagonistas del receptor de 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que los contienen
EP0664794A1 (de) * 1992-10-16 1995-08-02 Smithkline Beecham Plc N-alkylpiperidinyl-4-methyl-carbonsäure ester/amide von kondensierten ring-systemen als 5-ht4-rezeptor antagonisten
US5705498A (en) * 1992-11-05 1998-01-06 Smithkline Beecham Plc. Piperidine derivatives as 5-HT4 receptor antagonists
GB9301660D0 (en) * 1993-01-28 1993-03-17 Smithkline Beecham Plc Pharmaceuticals
GB9310582D0 (en) * 1993-05-22 1993-07-07 Smithkline Beecham Plc Pharmaceuticals
GB9312348D0 (en) * 1993-06-16 1993-07-28 Smithkline Beecham Plc Pharmaceuticals
IT1275903B1 (it) * 1995-03-14 1997-10-24 Boehringer Ingelheim Italia Esteri e ammidi della 1,4-piperidina disostituita
GB9702194D0 (en) 1997-02-04 1997-03-26 Lilly Co Eli Sulphonide derivatives
IT1291569B1 (it) * 1997-04-15 1999-01-11 Angelini Ricerche Spa Indazolammidi come agenti serotoninergici
GB9725933D0 (en) * 1997-12-05 1998-02-04 Smithkline Beecham Plc Pharmaceuticals
BR0113073A (pt) * 2000-08-07 2004-06-22 Glaxosmithkline Lab Sas Uso de antagonistas receptores 5ht4 na fabricação de um medicamento para a profilaxia ou tratamento de fibrilação atrial
IL158448A0 (en) * 2001-04-20 2004-05-12 Wyeth Corp Heterocyclylalkoxy- alkylthio-and-alkylaminobenzazole derivatives as 5-hydroxytryptamine-6 ligands
EA200301142A1 (ru) * 2001-04-20 2004-02-26 Уайт Производные гетероциклилокси-, -тиокси- и -аминобензазола в качестве лигандов 5-гидрокситриптамина-6
GB0211230D0 (en) 2002-05-16 2002-06-26 Medinnova Sf Treatment of heart failure
EP2445877B1 (de) * 2008-12-03 2014-07-23 Nanotherapeutics, Inc. Bicyclische verbindungen und verfahren zu deren herstellung und deren verwendung
AU2021479832C1 (en) * 2021-12-23 2026-04-16 Contemporary Amperex Technology (Hong Kong) Limited A/m/x crystalline material, photovoltaic device, and preparation methods thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60123485A (ja) * 1983-12-08 1985-07-02 Yoshitomi Pharmaceut Ind Ltd インド−ル−３−カルボキサミド誘導体
FR2557110B1 (fr) * 1983-12-23 1989-11-24 Sandoz Sa Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments
GB8527052D0 (en) * 1985-11-02 1985-12-04 Beecham Group Plc Compounds
DK623586A (da) * 1985-12-27 1987-06-28 Eisai Co Ltd Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne
CA2030051C (en) * 1989-11-17 2001-08-07 Haruhiko Kikuchi Indole derivatives

Also Published As

Publication number Publication date
EP0501322B1 (de) 1996-09-04
EP0501322A1 (de) 1992-09-02
WO1992014727A1 (en) 1992-09-03
FI933697A7 (fi) 1993-08-23
AP295A (en) 1993-12-29
CA2105179A1 (en) 1992-08-26
AU645402B2 (en) 1994-01-13
HU9302414D0 (en) 1993-11-29
MX9200762A (es) 1992-08-01
DE69213276D1 (de) 1996-10-10
ATE142205T1 (de) 1996-09-15
AP9200417A0 (en) 1992-10-31
FI933697L (fi) 1993-08-23
NO933015L (no) 1993-08-24
IL101042A0 (en) 1992-11-15
FI933697A0 (fi) 1993-08-23
ES2091963T3 (es) 1996-11-16
HUT65486A (en) 1994-06-28
GB9103862D0 (en) 1991-04-10
AU1209492A (en) 1992-09-15
NO933015D0 (no) 1993-08-24
CN1083059A (zh) 1994-03-02
JPH06505238A (ja) 1994-06-16
DE69213276T2 (de) 1997-01-23
IE920567A1 (en) 1992-08-26
NZ241704A (en) 1993-11-25

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