IL102400A - Germicidal compositions containing quaternary ammonium iodide compounds, their preparation and uses thereof - Google Patents
Germicidal compositions containing quaternary ammonium iodide compounds, their preparation and uses thereofInfo
- Publication number
- IL102400A IL102400A IL102400A IL10240092A IL102400A IL 102400 A IL102400 A IL 102400A IL 102400 A IL102400 A IL 102400A IL 10240092 A IL10240092 A IL 10240092A IL 102400 A IL102400 A IL 102400A
- Authority
- IL
- Israel
- Prior art keywords
- iodine
- germicidal
- compounds
- sterilizing
- composition
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 65
- 230000002070 germicidal effect Effects 0.000 title claims abstract description 55
- 150000001875 compounds Chemical class 0.000 title claims abstract description 19
- 238000002360 preparation method Methods 0.000 title claims description 8
- 125000001453 quaternary ammonium group Chemical group 0.000 title claims description 3
- 229940107816 ammonium iodide Drugs 0.000 title 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims abstract description 24
- 239000011630 iodine Substances 0.000 claims abstract description 24
- 229910052740 iodine Inorganic materials 0.000 claims abstract description 24
- 230000000694 effects Effects 0.000 claims abstract description 13
- 230000001954 sterilising effect Effects 0.000 claims abstract description 13
- 150000002497 iodine compounds Chemical class 0.000 claims abstract description 11
- 230000000249 desinfective effect Effects 0.000 claims abstract description 9
- 208000015181 infectious disease Diseases 0.000 claims abstract description 7
- 235000013305 food Nutrition 0.000 claims abstract description 5
- 238000009924 canning Methods 0.000 claims abstract description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerol Natural products OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 17
- 238000003756 stirring Methods 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 11
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 10
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 claims description 10
- 150000002496 iodine Chemical class 0.000 claims description 8
- 230000008569 process Effects 0.000 claims description 8
- 150000002191 fatty alcohols Chemical class 0.000 claims description 7
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims description 7
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims description 6
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 6
- 239000000194 fatty acid Substances 0.000 claims description 6
- 229930195729 fatty acid Natural products 0.000 claims description 6
- 150000004665 fatty acids Chemical class 0.000 claims description 6
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims description 5
- 239000002253 acid Substances 0.000 claims description 5
- 239000000417 fungicide Substances 0.000 claims description 5
- -1 quaternary ammonium amide Chemical class 0.000 claims description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims description 3
- 150000001408 amides Chemical class 0.000 claims description 3
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 3
- 239000011707 mineral Substances 0.000 claims description 3
- FRPZMMHWLSIFAZ-UHFFFAOYSA-N 10-undecenoic acid Chemical compound OC(=O)CCCCCCCCC=C FRPZMMHWLSIFAZ-UHFFFAOYSA-N 0.000 claims description 2
- KHAVLLBUVKBTBG-UHFFFAOYSA-N caproleic acid Natural products OC(=O)CCCCCCCC=C KHAVLLBUVKBTBG-UHFFFAOYSA-N 0.000 claims description 2
- 238000011068 loading method Methods 0.000 claims description 2
- 229960002703 undecylenic acid Drugs 0.000 claims description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract description 3
- 239000000460 chlorine Substances 0.000 abstract description 3
- 229910052801 chlorine Inorganic materials 0.000 abstract description 3
- 150000001805 chlorine compounds Chemical class 0.000 abstract description 3
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 18
- 241001465754 Metazoa Species 0.000 description 13
- 239000000126 substance Substances 0.000 description 13
- 238000010790 dilution Methods 0.000 description 11
- 239000012895 dilution Substances 0.000 description 11
- 244000052616 bacterial pathogen Species 0.000 description 10
- 238000004659 sterilization and disinfection Methods 0.000 description 9
- 238000002474 experimental method Methods 0.000 description 8
- 244000005700 microbiome Species 0.000 description 8
- 231100000331 toxic Toxicity 0.000 description 7
- 230000002588 toxic effect Effects 0.000 description 7
- 241000894006 Bacteria Species 0.000 description 5
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 5
- 239000003651 drinking water Substances 0.000 description 5
- 235000020188 drinking water Nutrition 0.000 description 5
- 206010011409 Cross infection Diseases 0.000 description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 231100000419 toxicity Toxicity 0.000 description 4
- 230000001988 toxicity Effects 0.000 description 4
- QJVOZXGJOGJKPT-IGHBBLSQSA-N (1r,2r,5s,11ar)-2-(prop-2-en-1-yl)-1,2,3,4,5,6,11,11a-octahydro-10h-1,5-methanopyrido[1,2-a][1,5]diazocin-10-one Chemical compound C([C@@H]12)C(=O)C=CN1C[C@@H]1CN[C@H](CC=C)[C@H]2C1 QJVOZXGJOGJKPT-IGHBBLSQSA-N 0.000 description 3
- 206010013975 Dyspnoeas Diseases 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 241000877401 Saccharomyces ellipsoideus Species 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 241000191967 Staphylococcus aureus Species 0.000 description 3
- 241000700605 Viruses Species 0.000 description 3
- QJVOZXGJOGJKPT-UHFFFAOYSA-N albine Natural products C12CC(=O)C=CN2CC2CNC(CC=C)C1C2 QJVOZXGJOGJKPT-UHFFFAOYSA-N 0.000 description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 3
- 230000000845 anti-microbial effect Effects 0.000 description 3
- 239000003899 bactericide agent Substances 0.000 description 3
- 230000000711 cancerogenic effect Effects 0.000 description 3
- 231100000315 carcinogenic Toxicity 0.000 description 3
- 230000001413 cellular effect Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 239000000975 dye Substances 0.000 description 3
- 239000002085 irritant Substances 0.000 description 3
- 231100000021 irritant Toxicity 0.000 description 3
- 230000000622 irritating effect Effects 0.000 description 3
- 230000003641 microbiacidal effect Effects 0.000 description 3
- 231100000219 mutagenic Toxicity 0.000 description 3
- 230000003505 mutagenic effect Effects 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 230000005855 radiation Effects 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 238000006467 substitution reaction Methods 0.000 description 3
- 241000700198 Cavia Species 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 2
- DZBUGLKDJFMEHC-UHFFFAOYSA-N acridine Chemical compound C1=CC=CC2=CC3=CC=CC=C3N=C21 DZBUGLKDJFMEHC-UHFFFAOYSA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- UKFWSNCTAHXBQN-UHFFFAOYSA-N ammonium iodide Chemical group [NH4+].[I-] UKFWSNCTAHXBQN-UHFFFAOYSA-N 0.000 description 2
- 239000000645 desinfectant Substances 0.000 description 2
- 229960004279 formaldehyde Drugs 0.000 description 2
- 235000019256 formaldehyde Nutrition 0.000 description 2
- 230000000855 fungicidal effect Effects 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 150000004820 halides Chemical class 0.000 description 2
- 239000000383 hazardous chemical Substances 0.000 description 2
- 231100000206 health hazard Toxicity 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 238000012009 microbiological test Methods 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 239000000344 soap Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- QLUMYZZMKLAMSN-UHFFFAOYSA-N (2,3,4,5,6-pentachlorophenyl) hypochlorite Chemical compound ClOC1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1Cl QLUMYZZMKLAMSN-UHFFFAOYSA-N 0.000 description 1
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- 241000228245 Aspergillus niger Species 0.000 description 1
- 241000194110 Bacillus sp. (in: Bacteria) Species 0.000 description 1
- ZKQDCIXGCQPQNV-UHFFFAOYSA-N Calcium hypochlorite Chemical compound [Ca+2].Cl[O-].Cl[O-] ZKQDCIXGCQPQNV-UHFFFAOYSA-N 0.000 description 1
- 229920003043 Cellulose fiber Polymers 0.000 description 1
- QDHHCQZDFGDHMP-UHFFFAOYSA-N Chloramine Chemical class ClN QDHHCQZDFGDHMP-UHFFFAOYSA-N 0.000 description 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 1
- 108010065152 Coagulase Proteins 0.000 description 1
- GUTLYIVDDKVIGB-OUBTZVSYSA-N Cobalt-60 Chemical compound [60Co] GUTLYIVDDKVIGB-OUBTZVSYSA-N 0.000 description 1
- 244000205754 Colocasia esculenta Species 0.000 description 1
- 235000006481 Colocasia esculenta Nutrition 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
- 235000011613 Pinus brutia Nutrition 0.000 description 1
- 241000018646 Pinus brutia Species 0.000 description 1
- 241000589776 Pseudomonas putida Species 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 241000122973 Stenotrophomonas maltophilia Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 231100000460 acute oral toxicity Toxicity 0.000 description 1
- 238000011047 acute toxicity test Methods 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000001299 aldehydes Chemical class 0.000 description 1
- 150000001449 anionic compounds Chemical class 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 229960000686 benzalkonium chloride Drugs 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 229960003260 chlorhexidine Drugs 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000005515 coenzyme Substances 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 150000001896 cresols Chemical class 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 230000001877 deodorizing effect Effects 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000002360 explosive Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005865 ionizing radiation Effects 0.000 description 1
- 150000002596 lactones Chemical class 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 150000002731 mercury compounds Chemical class 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
- 229940124561 microbicide Drugs 0.000 description 1
- 239000002855 microbicide agent Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 231100000350 mutagenesis Toxicity 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 230000002352 nonmutagenic effect Effects 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000009928 pasteurization Methods 0.000 description 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-N picric acid Chemical compound OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 239000012286 potassium permanganate Substances 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 231100000161 signs of toxicity Toxicity 0.000 description 1
- 229940100890 silver compound Drugs 0.000 description 1
- 150000003379 silver compounds Chemical class 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 239000002341 toxic gas Substances 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- YRIDFQASBDRMBJ-UHFFFAOYSA-N undec-10-enamide Chemical compound NC(=O)CCCCCCCCC=C YRIDFQASBDRMBJ-UHFFFAOYSA-N 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
- A01N37/20—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof containing the group, wherein Cn means a carbon skeleton not containing a ring; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Communicable Diseases (AREA)
- Agronomy & Crop Science (AREA)
- Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9101563A ES2037592B1 (es) | 1991-07-03 | 1991-07-03 | Procedimiento para preparar nuevos compuestos yodados con actividad germicida y fungicida. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL102400A0 IL102400A0 (en) | 1993-01-14 |
| IL102400A true IL102400A (en) | 1998-03-10 |
Family
ID=8272891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL102400A IL102400A (en) | 1991-07-03 | 1992-07-03 | Germicidal compositions containing quaternary ammonium iodide compounds, their preparation and uses thereof |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0534887B1 (ja) |
| JP (1) | JP3167724B2 (ja) |
| CN (1) | CN1045362C (ja) |
| AT (1) | ATE143766T1 (ja) |
| AU (1) | AU650350B2 (ja) |
| CA (1) | CA2073094C (ja) |
| DE (1) | DE69214399T2 (ja) |
| DK (1) | DK0534887T3 (ja) |
| ES (1) | ES2037592B1 (ja) |
| GR (1) | GR3022269T3 (ja) |
| IL (1) | IL102400A (ja) |
| MX (1) | MX9203941A (ja) |
| RU (1) | RU2128521C1 (ja) |
| WO (1) | WO1993000813A1 (ja) |
| ZA (1) | ZA924979B (ja) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5783604A (en) * | 1992-07-02 | 1998-07-21 | Garcia Nunez; Maria Rosalia | Germicidal compositions containing iodine compounds |
| ES2078139B1 (es) * | 1993-03-05 | 1996-08-01 | Nunez Maria Rosalia Garcia | Composiciones antirretrovirales que contienen compuestos iodados. |
| US6864269B2 (en) | 1996-04-12 | 2005-03-08 | University Of Arkansas | Concentrated, non-foaming solution of quarternary ammonium compounds and methods of use |
| US5855940A (en) * | 1996-04-12 | 1999-01-05 | University Of Arkansas | Method for the broad spectrum prevention and removal of microbial contamination of poultry and meat products by quaternary ammonium compounds |
| ES2141678B1 (es) * | 1998-03-25 | 2000-11-01 | Larios Garcia Jose | Composicion con actividad germicida a base de derivados del acido undecilenico. |
| JP4782980B2 (ja) * | 2002-07-03 | 2011-09-28 | 株式会社Ａｄｅｋａ | 抗菌剤 |
| WO2016015691A1 (en) | 2014-07-30 | 2016-02-04 | Albert SARKESSYAN | A pharmaceutical composition having antibacterial and virucidal effects |
| RU2595871C1 (ru) * | 2015-01-29 | 2016-08-27 | Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Саратовский Государственный Технический Университет Имени Гагарина Ю. А." (Сгту Имени Гагарина Ю.А.) | Бактерицидная композиция |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2679533A (en) * | 1951-11-03 | 1954-05-25 | California Research Corp | Addition products of halogen and quaternary ammonium germicides and method for making the same |
| GB948966A (en) * | 1961-06-05 | 1964-02-05 | Sterwin Ag | New bactericidal compounds, processes for their preparation, and pharmaceutical compositions incorporating them |
| CH443774A (de) * | 1963-05-30 | 1967-09-15 | Ciba Geigy | Mittel zur Bekämpfung phytopathogener Mikroorganismen |
| US3869483A (en) | 1972-06-23 | 1975-03-04 | Us Agriculture | Quaternary ammonium salts of n-substituted palmitamides |
| US4042368A (en) * | 1975-06-27 | 1977-08-16 | Epic Chemical Inc. | Additive for quaternary amine bactericides and algicides, compositions containing same and method of manufacture |
| SU940631A3 (ru) * | 1975-08-28 | 1982-06-30 | За витель К ПАТЕНТУ | Способ получени дезинфицирующего средства |
| IT1082339B (it) * | 1977-02-07 | 1985-05-21 | Zambelletti Dr L Spa | Composto ad attivita disinfettante e composizioni farmaceutiche che lo contengono |
| IT1094152B (it) * | 1978-02-24 | 1985-07-26 | Gambar Labor | Cloroioditi di ammonio quaternario ad azione antisettica,processo per la loro preparrazione e composizioni farmaceutiche che li contengono |
| DE3619748A1 (de) * | 1986-06-12 | 1987-12-17 | Merz & Co Gmbh & Co | Antimikrobielle mittel |
| DK86290D0 (da) * | 1990-04-06 | 1990-04-06 | Novo Nordisk As | Fungicide praeparater |
-
1991
- 1991-07-03 ES ES9101563A patent/ES2037592B1/es not_active Expired - Fee Related
-
1992
- 1992-07-02 AT AT92500084T patent/ATE143766T1/de not_active IP Right Cessation
- 1992-07-02 DE DE69214399T patent/DE69214399T2/de not_active Expired - Fee Related
- 1992-07-02 EP EP92500084A patent/EP0534887B1/en not_active Expired - Lifetime
- 1992-07-02 AU AU19401/92A patent/AU650350B2/en not_active Ceased
- 1992-07-02 DK DK92500084.6T patent/DK0534887T3/da active
- 1992-07-03 IL IL102400A patent/IL102400A/en not_active IP Right Cessation
- 1992-07-03 CN CN92109200A patent/CN1045362C/zh not_active Expired - Fee Related
- 1992-07-03 MX MX9203941A patent/MX9203941A/es not_active IP Right Cessation
- 1992-07-03 WO PCT/ES1992/000051 patent/WO1993000813A1/es not_active Ceased
- 1992-07-03 JP JP50198693A patent/JP3167724B2/ja not_active Expired - Fee Related
- 1992-07-03 ZA ZA924979A patent/ZA924979B/xx unknown
- 1992-07-03 RU RU93005225A patent/RU2128521C1/ru not_active IP Right Cessation
- 1992-07-03 CA CA002073094A patent/CA2073094C/en not_active Expired - Fee Related
-
1997
- 1997-01-10 GR GR970400039T patent/GR3022269T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2037592A1 (es) | 1993-06-16 |
| DK0534887T3 (da) | 1997-03-03 |
| JP3167724B2 (ja) | 2001-05-21 |
| GR3022269T3 (en) | 1997-04-30 |
| MX9203941A (es) | 1993-04-01 |
| DE69214399T2 (de) | 1997-03-20 |
| ATE143766T1 (de) | 1996-10-15 |
| DE69214399D1 (de) | 1996-11-14 |
| CA2073094A1 (en) | 1993-01-04 |
| CN1070083A (zh) | 1993-03-24 |
| AU650350B2 (en) | 1994-06-16 |
| CA2073094C (en) | 2002-05-28 |
| IL102400A0 (en) | 1993-01-14 |
| EP0534887B1 (en) | 1996-10-09 |
| WO1993000813A1 (es) | 1993-01-21 |
| ZA924979B (en) | 1993-04-28 |
| RU2128521C1 (ru) | 1999-04-10 |
| CN1045362C (zh) | 1999-10-06 |
| JPH06501495A (ja) | 1994-02-17 |
| AU1940192A (en) | 1993-03-11 |
| EP0534887A1 (en) | 1993-03-31 |
| ES2037592B1 (es) | 1994-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |