IL102980A - Benzopyran derivatives, their preparation and pharmaceutical compositions comprising them - Google Patents

Benzopyran derivatives, their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL102980A
IL102980A IL102980A IL10298092A IL102980A IL 102980 A IL102980 A IL 102980A IL 102980 A IL102980 A IL 102980A IL 10298092 A IL10298092 A IL 10298092A IL 102980 A IL102980 A IL 102980A
Authority
IL
Israel
Prior art keywords
methyl
benzopyran
oxo
dimethyl
formula
Prior art date
Application number
IL102980A
Other languages
English (en)
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of IL102980A publication Critical patent/IL102980A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL102980A 1991-08-29 1992-08-28 Benzopyran derivatives, their preparation and pharmaceutical compositions comprising them IL102980A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/751,491 US5250547A (en) 1991-08-29 1991-08-29 Benzopyran derivatives

Publications (1)

Publication Number Publication Date
IL102980A true IL102980A (en) 1998-04-05

Family

ID=25022219

Family Applications (1)

Application Number Title Priority Date Filing Date
IL102980A IL102980A (en) 1991-08-29 1992-08-28 Benzopyran derivatives, their preparation and pharmaceutical compositions comprising them

Country Status (15)

Country Link
US (2) US5250547A (it)
EP (1) EP0529654A1 (it)
JP (1) JPH05213940A (it)
KR (1) KR100235165B1 (it)
AU (1) AU653245B2 (it)
CA (1) CA2077098A1 (it)
FI (1) FI923872A7 (it)
HU (1) HUT65384A (it)
IL (1) IL102980A (it)
IT (1) IT1256948B (it)
MX (1) MX9205003A (it)
NO (1) NO302233B1 (it)
NZ (1) NZ244123A (it)
TW (1) TW203611B (it)
ZA (1) ZA926549B (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0549729B1 (en) * 1990-09-07 1997-12-17 Schering Corporation Antiviral compounds and antihypertensive compounds
CA2148220A1 (en) * 1992-11-06 1994-05-26 Kiyoshi Tamura Method for producing composition for solid medicine
GB9226302D0 (en) * 1992-12-17 1993-02-10 Smithkline Beecham Plc Pharmaceuticals
US5482942A (en) * 1994-06-28 1996-01-09 American Home Products Corporation (3,4-dioxocyclobuten-1-yl)chromene, indene, and dihydronaphthalenone derivatives as smooth muscle relaxants
TW533073B (en) * 1997-03-03 2003-05-21 Chugai Pharmaceutical Co Ltd Therapeutic agents for peripheral vascular disease
US6077850A (en) * 1997-04-21 2000-06-20 G.D. Searle & Co. Substituted benzopyran analogs for the treatment of inflammation
US6034256A (en) 1997-04-21 2000-03-07 G.D. Searle & Co. Substituted benzopyran derivatives for the treatment of inflammation
CA2307285C (en) 1998-08-17 2009-03-31 Senju Pharmaceutical Co., Ltd. Agent for prophylaxis and treatment of glaucoma
US20040198800A1 (en) * 2002-12-19 2004-10-07 Geoffrey Allan Lipoxygenase inhibitors as hypolipidemic and anti-hypertensive agents
WO2005033093A1 (en) 2003-09-19 2005-04-14 Galileo Pharmaceuticals, Inc. 7,8-bicycloalkyl-chroman derivatives
KR100602191B1 (ko) * 2004-03-10 2006-07-19 한국화학연구원 5-라이폭시게네이즈 저해활성을 가지는2,2'-이중치환-3,4-디하이드로-7,8-이중치환-6-알킬아미노벤조피란 유도체
AU2005316739A1 (en) 2004-12-13 2006-06-22 Galileo Pharmaceuticals, Inc. Spiro derivatives as lipoxygenase inhibitors
AU2005328328A1 (en) * 2005-02-25 2006-09-08 Galileo Pharmaceuticals, Inc. Spiro-heterocyclic chromans, thiochromans and dihydroquinolines
JP2006306791A (ja) * 2005-04-28 2006-11-09 Kanebo Cosmetics Inc 養毛剤
KR100704009B1 (ko) * 2005-08-30 2007-04-04 한국화학연구원 염증억제 활성을 가지는6-알킬아미노-2-메틸-2'-(ｎ-메틸치환술폰아미도)메틸-2ｈ-1-벤조피란 유도체
SG175390A1 (en) 2009-04-29 2011-12-29 Amarin Corp Plc Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2630110B1 (fr) * 1988-04-13 1990-07-27 Adir Nouveaux derives heteroarotinoides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5021432A (en) * 1988-04-26 1991-06-04 Yoshitomi Pharmaceutical Industries, Ltd. Benzopyran compound and its pharmaceutical use
EP0373204A1 (en) * 1988-05-09 1990-06-20 Beecham Group Plc Novel compounds and treatment
NZ231969A (en) * 1988-12-23 1992-09-25 Beecham Group Plc Benzopyran derivatives, analogues, precursors, and medicaments
US4908378A (en) * 1989-04-12 1990-03-13 American Home Products Corporation Benzopyran derivatives and antihypertensive use thereof
GB8916683D0 (en) * 1989-07-21 1989-09-06 Beecham Group Plc Novel compounds
DE3924417A1 (de) * 1989-07-24 1991-01-31 Merck Patent Gmbh Chromanderivate
DE3926001A1 (de) * 1989-08-05 1991-02-07 Merck Patent Gmbh Chromanderivate
US5053523A (en) * 1989-09-19 1991-10-01 Allergan, Inc. Ethynyl-chroman compounds
CA2070243A1 (en) * 1991-06-14 1992-12-15 Akira Shiozawa Chroman derivatives

Also Published As

Publication number Publication date
KR100235165B1 (ko) 1999-12-15
NZ244123A (en) 1995-06-27
JPH05213940A (ja) 1993-08-24
CA2077098A1 (en) 1993-03-01
TW203611B (it) 1993-04-11
ZA926549B (en) 1994-02-28
HU9202777D0 (en) 1992-12-28
NO923382D0 (no) 1992-08-28
ITTO920719A0 (it) 1992-08-28
AU2133392A (en) 1993-03-11
US5250547A (en) 1993-10-05
HUT65384A (en) 1994-05-02
EP0529654A1 (en) 1993-03-03
FI923872A0 (fi) 1992-08-28
FI923872A7 (fi) 1993-03-01
AU653245B2 (en) 1994-09-22
US5447943A (en) 1995-09-05
NO302233B1 (no) 1998-02-09
IT1256948B (it) 1995-12-27
ITTO920719A1 (it) 1994-02-28
KR930004290A (ko) 1993-03-22
NO923382L (no) 1993-03-01
MX9205003A (es) 1993-04-30

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Legal Events

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KB Patent renewed
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MM9K Patent not in force due to non-payment of renewal fees