IL103898A - Process for preparing 2-substituted 4,6-dialkoxypyrimidines and certain 2-alkylamino-4,6-dialkoxypyrimidines - Google Patents

Process for preparing 2-substituted 4,6-dialkoxypyrimidines and certain 2-alkylamino-4,6-dialkoxypyrimidines

Info

Publication number
IL103898A
IL103898A IL10389892A IL10389892A IL103898A IL 103898 A IL103898 A IL 103898A IL 10389892 A IL10389892 A IL 10389892A IL 10389892 A IL10389892 A IL 10389892A IL 103898 A IL103898 A IL 103898A
Authority
IL
Israel
Prior art keywords
denotes
general formula
formula
group
hydrogen
Prior art date
Application number
IL10389892A
Other languages
English (en)
Other versions
IL103898A0 (en
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of IL103898A0 publication Critical patent/IL103898A0/xx
Publication of IL103898A publication Critical patent/IL103898A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Liquid Crystal Substances (AREA)
IL10389892A 1991-11-26 1992-11-26 Process for preparing 2-substituted 4,6-dialkoxypyrimidines and certain 2-alkylamino-4,6-dialkoxypyrimidines IL103898A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH345491 1991-11-26

Publications (2)

Publication Number Publication Date
IL103898A0 IL103898A0 (en) 1993-04-04
IL103898A true IL103898A (en) 1998-10-30

Family

ID=4256295

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10389892A IL103898A (en) 1991-11-26 1992-11-26 Process for preparing 2-substituted 4,6-dialkoxypyrimidines and certain 2-alkylamino-4,6-dialkoxypyrimidines

Country Status (15)

Country Link
US (1) US5266697A (de)
EP (1) EP0547411B1 (de)
JP (1) JP3266951B2 (de)
KR (1) KR100233068B1 (de)
AT (1) ATE176463T1 (de)
CA (1) CA2083790C (de)
CZ (1) CZ282446B6 (de)
DE (1) DE59209632D1 (de)
ES (1) ES2128336T3 (de)
FI (1) FI111842B (de)
HU (2) HU212611B (de)
IL (1) IL103898A (de)
RU (1) RU2117007C1 (de)
SK (1) SK278153B6 (de)
ZA (1) ZA929131B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4331223A1 (de) * 1992-12-24 1994-06-30 Sueddeutsche Kalkstickstoff Verfahren zur Herstellung von 2-Ethoxy-4,6-dihydroxypyrimidin oder dessen Alkalisalz
US5552546A (en) * 1994-07-28 1996-09-03 Dowelanco Process for the preparation of 2-ethoxy-4,6-dihydroxypyrimidine
DE19517186A1 (de) * 1995-05-11 1996-11-14 Bayer Ag Verfahren zur Herstellung substituierter 2-Fluor-pyrimidine
TWI220428B (en) * 1999-02-05 2004-08-21 Syngenta Participations Ag Method of producing thiobarbituric acid derivatives
AU2001289701B2 (en) * 2000-07-21 2004-06-24 Syngenta Participations Ag Process for the preparation of 4,6-dimethoxy-2-(methylsulfonyl)-1,3-pyrimidine
ATE394380T1 (de) * 2001-10-17 2008-05-15 Lonza Ag Verfahren zur herstellung von (pyrimidin-2- yl)methylketonen
CN100447135C (zh) * 2005-06-20 2008-12-31 江苏省激素研究所有限公司 2-氯-4,6-二甲氧基嘧啶的制备方法
CN102285925A (zh) * 2010-06-18 2011-12-21 北京英力精化技术发展有限公司 2-氯-4,6-二丁氧基嘧啶的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1545839A1 (de) * 1965-07-24 1969-10-16 Bayer Ag Verfahren zur Herstellung substituierter Pyrimidine
AR225772A1 (es) * 1979-08-14 1982-04-30 Du Pont Nuevo 3-amino-3-alcoxi-n-ciano-2-propenimidato de alquilo y procedimientos para su preparacion y de pirimidinas partiendo de aquellos
JPH082883B2 (ja) * 1986-06-06 1996-01-17 クミアイ化学工業株式会社 ２−フエノキシピリミジン誘導体および除草剤
DE3642832A1 (de) * 1986-12-16 1988-06-30 Hoechst Ag Verfahren zur herstellung von aminopyrimidinen
JP2561480B2 (ja) * 1987-08-06 1996-12-11 イハラケミカル工業株式会社 ４，６−ジアルコキシ−２−アルキルチオピリミジン類の製造方法
GB8912700D0 (en) * 1989-06-02 1989-07-19 Shell Int Research Herbicidal compounds

Also Published As

Publication number Publication date
FI111842B (fi) 2003-09-30
ZA929131B (en) 1993-05-25
HUT64043A (en) 1993-11-29
CZ282446B6 (cs) 1997-07-16
ES2128336T3 (es) 1999-05-16
KR100233068B1 (ko) 1999-12-01
RU2117007C1 (ru) 1998-08-10
JPH05194423A (ja) 1993-08-03
ATE176463T1 (de) 1999-02-15
EP0547411B1 (de) 1999-02-03
DE59209632D1 (de) 1999-03-18
SK348792A3 (en) 1996-02-07
CZ348792A3 (en) 1993-09-15
JP3266951B2 (ja) 2002-03-18
IL103898A0 (en) 1993-04-04
HU212611B (en) 1996-09-30
US5266697A (en) 1993-11-30
CA2083790C (en) 2001-04-03
SK278153B6 (en) 1996-02-07
FI925258A7 (fi) 1993-05-27
HU9203731D0 (en) 1993-03-29
EP0547411A1 (de) 1993-06-23
KR930010008A (ko) 1993-06-21
CA2083790A1 (en) 1993-05-27
FI925258A0 (fi) 1992-11-19

Similar Documents

Publication Publication Date Title
EP0757678B1 (de) Verfahren zur herstellung von 4,6-dichloropyrimidin
EP0483204B1 (de) Verfahren zur herstellung von 2,5-diamino-4,6-dichlorpyrimidin
EP1636231B1 (de) Herstellungsverfahren für 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurin unter verwendung einer verbindung von 2-amino-9-(2-substituierte ethyl)purine
EP1551839B1 (de) Verfahren zur herstellung von 9-¬4-acetoxy-3-(acetoxymethyl)but-1-yl -2-aminopurin
NO328103B1 (no) Fremgangsmate for fremstilling av 2-amino-4-(4-fluorfenyl)-6-alkylpyrimidin-5-karboksylater og mellomprodukter derav
US5274166A (en) Dithiocarbamic acid salt, process for production thereof, and process for production of isothiocyanate using said dithiocarbamic acid salt
US5266697A (en) Process for the production of 2-substituted 4,6-dialkoxypyrimidines
KR100369274B1 (ko) 4-히드록시-2-피롤리돈의개량제법
US4985563A (en) Process for the preparation of 6-piperidino-2,4-diamino pyrimidine-3-oxide
KR870002019B1 (ko) 아민유도체의 제조방법
JP3602796B2 (ja) チオバルビツール酸誘導体の製法
JPH10130244A (ja) アシクロヌクレオシドの製造方法
US6197964B1 (en) Method for the production of 2,6-dichloro-5-fluoronicotinonitrile and the chemical compound 3-cyano-2-hydroxy-5-fluoropyride-6-one-monosodium salt its tautomers
JPH11147879A (ja) 非対称４，６−ビス（アリールオキシ）ピリミジン化合物の改良された製造方法
JP2991832B2 (ja) ピリミジン誘導体の製造方法
JP2659587B2 (ja) ４―アジリジニルピリミジン誘導体及びその製造法
JPH10168068A (ja) アシクロヌクレオシドの製造方法
US4723006A (en) Process for 4,6-di-substituted 2-aminopyrimidines
Pochat et al. Synthesis and experimental anti-tumor activities of 6-alkyl (or aryl) thio 5-deazapteridines
IE53383B1 (en) Chemical process
Hirota et al. Pyrimidine derivatives and related compounds. Part 36. Nucleophilic addition reaction of a cyanide lon to 6-substituted 1, 3-dimethyl-5-nitrouracils. Synthesis of 5, 6-dihydrouracil and 5, 6-dihydrocyclo-thymine derivatives
JPH02221261A (ja) ２，４―ジアミノ―６―置換―ピリミジン―３―オキサイドの製造方法
JPH0710859B2 (ja) ビスアゾリルピリミジン誘導体の製造方法
JPS59152359A (ja) アルコキシメチレンマロノニトリルの製造法
NO168703B (no) Utgangsforbindelse for anvendelse ved fremstilling av pyrrolidinderivater

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees