IL108931A - Derivatives of 2-amino-n- (4-aminobutyl)-4-oxo-6- (1' 2-di- and 1, 2, 3-trihydroxypropyl)- pteridinebutanamide, their preparation and their use - Google Patents

Derivatives of 2-amino-n- (4-aminobutyl)-4-oxo-6- (1' 2-di- and 1, 2, 3-trihydroxypropyl)- pteridinebutanamide, their preparation and their use

Info

Publication number
IL108931A
IL108931A IL108931A IL10893194A IL108931A IL 108931 A IL108931 A IL 108931A IL 108931 A IL108931 A IL 108931A IL 10893194 A IL10893194 A IL 10893194A IL 108931 A IL108931 A IL 108931A
Authority
IL
Israel
Prior art keywords
preparation
derivatives
pteridinebutanamide
trihydroxypropyl
aminobutyl
Prior art date
Application number
IL108931A
Other languages
English (en)
Other versions
IL108931A0 (en
Original Assignee
Henning Berlin Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henning Berlin Gmbh filed Critical Henning Berlin Gmbh
Publication of IL108931A0 publication Critical patent/IL108931A0/xx
Publication of IL108931A publication Critical patent/IL108931A/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B17/00—Azine dyes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL108931A 1993-03-19 1994-03-10 Derivatives of 2-amino-n- (4-aminobutyl)-4-oxo-6- (1' 2-di- and 1, 2, 3-trihydroxypropyl)- pteridinebutanamide, their preparation and their use IL108931A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4308739A DE4308739C1 (de) 1993-03-19 1993-03-19 Pterinderivate, ihre Herstellung und ihre Verwendung

Publications (2)

Publication Number Publication Date
IL108931A0 IL108931A0 (en) 1994-06-24
IL108931A true IL108931A (en) 1997-03-18

Family

ID=6483186

Family Applications (1)

Application Number Title Priority Date Filing Date
IL108931A IL108931A (en) 1993-03-19 1994-03-10 Derivatives of 2-amino-n- (4-aminobutyl)-4-oxo-6- (1' 2-di- and 1, 2, 3-trihydroxypropyl)- pteridinebutanamide, their preparation and their use

Country Status (9)

Country Link
US (1) US5698408A (de)
EP (1) EP0689541B1 (de)
JP (1) JPH09504505A (de)
AT (1) ATE143962T1 (de)
AU (1) AU6257994A (de)
DE (2) DE4308739C1 (de)
IL (1) IL108931A (de)
WO (1) WO1994021636A1 (de)
ZA (1) ZA941913B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506567B2 (en) * 2000-01-31 2003-01-14 Fuji Photo Film Co., Ltd. Water-soluble flourescent intercalator compound
US7442372B2 (en) 2003-08-29 2008-10-28 Biomarin Pharmaceutical Inc. Delivery of therapeutic compounds to the brain and other tissues
WO2005048926A2 (en) * 2003-11-13 2005-06-02 The General Hospital Corporation Methods for treating pain
PL1708690T3 (pl) 2003-11-17 2017-01-31 Biomarin Pharmaceutical Inc. Leczenie fenyloketonurii za pomocą BH4
KR20070084270A (ko) 2004-11-17 2007-08-24 바이오마린 파머수티컬 인크. 안정한 정제 제형물
JP2008523090A (ja) * 2004-12-08 2008-07-03 バイオマリン ファーマシューティカル インコーポレイテッド 新生児肺高血圧症の治療のための方法および組成物
WO2007067570A1 (en) * 2005-12-05 2007-06-14 Biomarin Pharmaceutical Inc. Methods and compositions for the treatment of disease
US20100009997A1 (en) * 2007-01-12 2010-01-14 Biomarin Pharmaceutical Inc. Method of treating a metabolic or neuropsychiarty disorder with a bh4 derivative prodrug
CA2675134A1 (en) * 2007-01-12 2008-07-24 Biomarin Pharmaceutical Inc. Pterin analogs
LT2545939T (lt) 2007-04-11 2021-03-10 Biomarin Pharmaceutical Inc. Tetrahidrobiopterinas, skirtas gydyti ligas, susijusias supadidėjusiu fenilalanino kiekiu
RU2470642C2 (ru) * 2008-01-03 2012-12-27 Байомарин Фармасьютикл Инк. Аналоги птерина для лечения состояния, чувствительного к вн4
BRPI0907247A2 (pt) * 2008-01-07 2015-07-14 Biomarin Pharm Inc Métodos para preparar biopterina e para preparar tetraidrobiopterina
EP2438447B1 (de) * 2009-06-05 2015-02-18 B.R.A.H.M.S GmbH Nachweis von bakteriellen Infektionen bei an Dyspnoe leidenden Patienten.
US20120115244A1 (en) 2010-11-09 2012-05-10 Abbott Laboratories Materials and methods for immunoassay of pterins
US9216178B2 (en) 2011-11-02 2015-12-22 Biomarin Pharmaceutical Inc. Dry blend formulation of tetrahydrobiopterin
WO2019175328A1 (en) 2018-03-14 2019-09-19 Imba - Institut Für Molekulare Biotechnologie Gmbh Bh4pathwayactivationandusethereoffortreatingcancer
WO2019175332A1 (en) 2018-03-14 2019-09-19 Imba - Institut Für Molekulare Biotechnologie Gmbh Bh4 pathway inhibition and use thereof for treating t-cell mediated autoimmune diseases or hypersensitivity

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE301292C (de) *
GB2056459B (en) * 1979-07-04 1983-03-09 Daiichi Radioisotope Lab Pterin derivatives and an assay method for determining pterins
JPS57158783A (en) * 1981-03-26 1982-09-30 Daiichi Rajio Isotope Kenkyusho:Kk Pterin derivative
EP0370960A1 (de) * 1988-11-21 1990-05-30 Ivo E. Pera Neopterin als Marker in einem diagnostischen Testkit zum Nachweis von retroviralen Krankheiten
JPH0757754B2 (ja) * 1989-09-02 1995-06-21 学校法人藤田学園 ビオプテリン，ネオプテリン及び天然プテリジンの酵素免疫測定法及びそのための支持体
DE9217853U1 (de) * 1992-12-30 1993-03-25 Educational Foundation Fujita Gakuen, Toyoake, Aichi 2-(3-Aminopropyl)-amino-4-hydroxy-6-[(1'R,2'S)-1',2'-dihydroxypropyl]-pteridin, Diagnostikum für cancerogene Erkrankungen und Mittel zur quantitativen Bestimmung von Oncopterin

Also Published As

Publication number Publication date
DE69400709D1 (de) 1996-11-14
DE69400709T2 (de) 1997-05-15
ZA941913B (en) 1995-09-18
DE4308739C1 (de) 1994-06-23
JPH09504505A (ja) 1997-05-06
US5698408A (en) 1997-12-16
EP0689541A1 (de) 1996-01-03
EP0689541B1 (de) 1996-10-09
AU6257994A (en) 1994-10-11
IL108931A0 (en) 1994-06-24
ATE143962T1 (de) 1996-10-15
WO1994021636A1 (en) 1994-09-29

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