IL113433A - Tablet formulations comprising amoxycillin and salts of clavulanic acid - Google Patents

Tablet formulations comprising amoxycillin and salts of clavulanic acid

Info

Publication number
IL113433A
IL113433A IL11343395A IL11343395A IL113433A IL 113433 A IL113433 A IL 113433A IL 11343395 A IL11343395 A IL 11343395A IL 11343395 A IL11343395 A IL 11343395A IL 113433 A IL113433 A IL 113433A
Authority
IL
Israel
Prior art keywords
amoxycillin
salts
clavulanic acid
tablet formulations
formulations
Prior art date
Application number
IL11343395A
Other languages
English (en)
Other versions
IL113433A0 (en
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10754044&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL113433(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of IL113433A0 publication Critical patent/IL113433A0/xx
Publication of IL113433A publication Critical patent/IL113433A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL11343395A 1994-04-23 1995-04-20 Tablet formulations comprising amoxycillin and salts of clavulanic acid IL113433A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9408117A GB9408117D0 (en) 1994-04-23 1994-04-23 Pharmaceutical formulations

Publications (2)

Publication Number Publication Date
IL113433A0 IL113433A0 (en) 1995-07-31
IL113433A true IL113433A (en) 2003-06-24

Family

ID=10754044

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11343395A IL113433A (en) 1994-04-23 1995-04-20 Tablet formulations comprising amoxycillin and salts of clavulanic acid

Country Status (35)

Country Link
US (1) US6051255A (de)
EP (5) EP1093813B1 (de)
JP (1) JP3622975B2 (de)
CN (1) CN1134258C (de)
AP (2) AP564A (de)
AT (6) ATE203161T1 (de)
AU (1) AU684949B2 (de)
BG (1) BG62842B1 (de)
BR (1) BR9507502A (de)
CA (1) CA2188496A1 (de)
CZ (2) CZ11376U1 (de)
DE (5) DE29522153U1 (de)
DK (4) DK0978276T3 (de)
DZ (1) DZ1876A1 (de)
ES (4) ES2180251T3 (de)
FI (1) FI964249A7 (de)
GB (1) GB9408117D0 (de)
GR (2) GR3035031T3 (de)
HK (1) HK1050992A1 (de)
HU (1) HU228399B1 (de)
IL (1) IL113433A (de)
MA (1) MA23528A1 (de)
MY (1) MY115351A (de)
NO (1) NO310703B1 (de)
NZ (1) NZ285080A (de)
OA (1) OA10377A (de)
PL (1) PL316966A1 (de)
PT (4) PT758235E (de)
RO (1) RO116997B1 (de)
RU (1) RU2152213C1 (de)
SA (1) SA95160343B1 (de)
SI (1) SI0758235T1 (de)
SK (1) SK282594B6 (de)
WO (1) WO1995028927A1 (de)
ZA (1) ZA953236B (de)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9407386D0 (en) 1994-04-14 1994-06-08 Smithkline Beecham Plc Pharmaceutical formulation
GB9408117D0 (en) * 1994-04-23 1994-06-15 Smithkline Beecham Corp Pharmaceutical formulations
DZ2028A1 (fr) * 1995-05-03 2002-10-23 Smithkline Beecham Plc Médicaments destinés au traitement d'infections bactériennes en pédiatrie.
US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
DK0862431T3 (da) 1995-09-07 2002-03-11 Smithkline Beecham Plc Anvendelse af pædiatrisk farmaceutisk formulering omfattende amoxycillin og clavulanat
AT403375B (de) * 1995-11-15 1998-01-26 Biochemie Gmbh Verfahren zur fällung von alkalisalzen der clavulansäure
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
AT407701B (de) * 1996-08-12 2001-05-25 Biochemie Gmbh Zur direkttablettierung geeignete mischung, die als wesentliche komponenten amoxicillin-trihydrat und das kaliumsalz der clavulansäure enthält und verfahren zur herstellung dieser mischung
GB9613470D0 (en) 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
GB9616536D0 (en) 1996-08-06 1996-09-25 Quadrant Holdings Cambridge Co-amoxiclav dosage form
GB9617780D0 (en) * 1996-08-24 1996-10-02 Smithkline Beecham Plc Method of treatment
AU6496498A (en) * 1997-02-07 1998-08-26 Gist-Brocades B.V. Homogeneous granulated formulations for dose sipping technology
SK110299A3 (en) * 1997-02-14 2000-08-14 Smithkline Beecham Lab Pharmaceutical formulations comprising amoxocyllin and clavulanate, preparation method and use thereof
US20030124187A1 (en) * 1997-02-14 2003-07-03 Smithkline Beecham Laboratoires Pharmaceutiques, Pharmaceutical formulations comprising amoxycillin and clavulanate
AU9540898A (en) * 1997-08-29 1999-03-22 Dsm N.V. Granules free of excipients
US6326028B1 (en) 1997-10-31 2001-12-04 Monsanto Company Alginate and gellan gum as tablet coating
CN1209099C (zh) 1999-04-01 2005-07-06 Dsm公司 结晶化附聚物
US7250176B1 (en) 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
US6294199B1 (en) * 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
IL145580A0 (en) * 1999-04-13 2002-11-10 Beecham Pharm Pte Ltd A modified release pharmaceutical composition comprising amoxycillin and potassium clavulanate
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
US20040038948A1 (en) * 1999-12-07 2004-02-26 Uhrich Kathryn E. Therapeutic compositions and methods
GB9930578D0 (en) * 1999-12-23 2000-02-16 Smithkline Beecham Plc Pharmaceutical formulations
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
WO2002002081A1 (en) * 2000-07-05 2002-01-10 Capricorn Pharma, Inc. Rapid-melt semi-solid compositions, methods of making same and methods of using same
US6375982B1 (en) * 2000-07-05 2002-04-23 Capricorn Pharma, Inc. Rapid-melt semi-solid compositions, methods of making same and method of using same
US6756057B2 (en) * 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
AU2001292185A1 (en) * 2000-10-12 2002-04-22 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin
US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
US20040156900A1 (en) * 2001-04-10 2004-08-12 Shanghvi Dilip Shantilal Time pulsed release composition
AU4061702A (en) * 2001-05-15 2003-04-03 Mcneil-Ppc, Inc. Dip coating compositions containing starch or dextrin
US20030070584A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
US8309118B2 (en) * 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
WO2003066053A1 (en) * 2002-02-07 2003-08-14 Rutgers, The State University Antibiotic polymers
BR0307666A (pt) * 2002-02-14 2005-01-11 Glaxo Group Ltd Composição farmacêutica compreendendo n-[(1-n-butil-4-piperidinil)metil]-3,4-diidro-2h[1-3]oxazi no(3,2-a) indol-10-carboxamida ou sal e processo para esta compreendendo granulação seca
GB0203528D0 (en) * 2002-02-14 2002-04-03 Glaxo Group Ltd Process and composition
US20060083759A1 (en) * 2002-07-17 2006-04-20 Aleksander Resman Stabilization of the profile of release of active substances from a formulation
US8637512B2 (en) 2002-07-29 2014-01-28 Glaxo Group Limited Formulations and method of treatment
KR100456833B1 (ko) * 2002-08-01 2004-11-10 주식회사 대웅 아목시실린 및 클라불라네이트를 함유하는 유핵정
US7429619B2 (en) * 2002-08-02 2008-09-30 Mcneil Consumer Healthcare Polyacrylic film forming compositions
CA2406592C (en) * 2002-10-04 2003-09-30 Duchesnay Inc. Method of preparing pharmaceutical dosage forms containing multiple active ingredients
US7405210B2 (en) 2003-05-21 2008-07-29 Osi Pharmaceuticals, Inc. Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase
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JP2006528185A (ja) * 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
JP2006528190A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
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JP5686494B2 (ja) * 2003-08-29 2015-03-18 シオノギ インコーポレイテッド 抗生物質製剤、その使用法及び作成方法
DE10341264A1 (de) 2003-09-04 2005-03-24 Grünenthal GmbH Schmelzformulierte, multipartikuläre orale Darreichungsform
EP1663169A4 (de) * 2003-09-15 2010-11-24 Middlebrook Pharmaceuticals In Antibiotisches produkt, seine verwendung und formulierung
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ATE483708T1 (de) 2004-03-08 2010-10-15 Prosidion Ltd Pyrrolopyridin-2-carbonsäurehydrazide als inhibitoren von glykogenphosphorylase
WO2006014427A1 (en) * 2004-07-02 2006-02-09 Advancis Pharmaceutical Corporation Tablet for pulsed delivery
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JP5000491B2 (ja) 2005-05-20 2012-08-15 第一三共株式会社 フィルムコーティング製剤
KR100780553B1 (ko) * 2005-08-18 2007-11-29 한올제약주식회사 메트포르민 서방정 및 그의 제조방법
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
CL2008003230A1 (es) * 2007-11-01 2009-11-27 Sanofi Aventis Healthcare Pty Ltd Composicion de recubrimiento de tableta que comprende polimero celulosico, plastificante, edulcorante y composicion de sabor en polvo la que comprende saborizante asociado con portador solido; fluido de recubrimiento de tableta que comprende dicha composicion; tableta farmaceutica; proceso de preparacion de dicha tableta.
CA2772275A1 (en) * 2009-09-18 2011-03-24 Sanofi (z)-2-cyano-3-hydroxy-but-2-enoic acid-(4'-trifluormethylphenyl)-amide tablet formulations with improved stability
TR200909787A2 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Üçüncü kuşak bir sefalosporin ve klavulanik asit içeren farmasötik formülasyonlar.
TR201000687A1 (tr) 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Aktif madde olarak sefiksim ve klavulanik asit içeren efervesan formülasyonlar
TR201000688A2 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Aktif madde olarak sefaklor ve klavulanik asit içeren efervesan formülasyonlar.
TR201000686A1 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@
JP6041591B2 (ja) * 2011-09-13 2016-12-14 大日本住友製薬株式会社 イルベサルタンとアムロジピンまたはその塩を含有する安定化された医薬組成物
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1241844A (en) 1968-08-23 1971-08-04 Beecham Group Ltd Penicillins
GB1508977A (en) 1974-04-20 1978-04-26 Beecham Group Ltd Beta-lactam antibiotic from streptomyces clavuligerus
US4098897A (en) * 1975-04-14 1978-07-04 Beecham Group Limited Anti bacterial agents
JO984B1 (en) * 1977-10-11 1979-12-01 بيتشام غروب ليمتد A dry pharmaceutical compound with a suitable dosage unit for oral administration
NZ198241A (en) * 1980-09-27 1983-12-16 Beecham Group Ltd Tablet containing amoxycillin and potassium clavulanate
EP0080862B1 (de) * 1981-12-02 1985-09-25 Beecham Group Plc Pharmazeutische Zubereitung die Beta-Lactam Antibiotika enthält
GB9408117D0 (en) * 1994-04-23 1994-06-15 Smithkline Beecham Corp Pharmaceutical formulations
IL145580A0 (en) * 1999-04-13 2002-11-10 Beecham Pharm Pte Ltd A modified release pharmaceutical composition comprising amoxycillin and potassium clavulanate
AU2001292185A1 (en) * 2000-10-12 2002-04-22 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin

Also Published As

Publication number Publication date
DK0761218T3 (da) 2000-12-18
EP0761218A1 (de) 1997-03-12
US6051255A (en) 2000-04-18
NO310703B1 (no) 2001-08-20
EP0761218B1 (de) 2000-10-11
AU684949B2 (en) 1998-01-08
DK0758235T3 (da) 2001-10-29
AP9500733A0 (en) 1995-04-30
OA10377A (en) 2001-11-21
PT1093813E (pt) 2003-02-28
DE69521799T2 (de) 2002-06-13
SK135496A3 (en) 1997-05-07
GR3036844T3 (en) 2002-01-31
MY115351A (en) 2003-05-31
CZ11376U1 (cs) 2001-07-12
ES2161288T3 (es) 2001-12-01
ES2180251T3 (es) 2003-02-01
CZ294168B6 (cs) 2004-10-13
SI0758235T1 (en) 2001-10-31
ATE226074T1 (de) 2002-11-15
ES2182754T3 (es) 2003-03-16
DE69528204T2 (de) 2003-08-07
CA2188496A1 (en) 1995-11-02
NO964488L (no) 1996-12-17
HU228399B1 (en) 2013-03-28
EP0978276A2 (de) 2000-02-09
RU2152213C1 (ru) 2000-07-10
DE69528608D1 (de) 2002-11-21
EP0758235B1 (de) 2001-07-18
HU9602922D0 (en) 1996-12-30
WO1995028927A1 (en) 1995-11-02
NO964488D0 (no) 1996-10-22
DE69528204D1 (de) 2002-10-17
DZ1876A1 (fr) 2002-02-17
AP9600868A0 (en) 1996-10-31
EP1093813A2 (de) 2001-04-25
HUT76335A (en) 1997-08-28
EP1093813A3 (de) 2001-05-30
DE69519093T2 (de) 2001-07-19
PT758235E (pt) 2001-10-31
AT5350U1 (de) 2002-06-25
DE69521799D1 (de) 2001-08-23
BG100933A (en) 1997-07-31
HK1027024A1 (en) 2001-01-05
DE69519093D1 (de) 2000-11-16
MA23528A1 (fr) 1995-12-31
AT5349U1 (de) 2002-06-25
AP564A (en) 1996-11-21
HK1021860A1 (en) 2000-07-07
EP1093813B1 (de) 2002-10-16
FI964249L (fi) 1996-10-22
PT761218E (pt) 2001-03-30
PL316966A1 (en) 1997-03-03
FI964249A0 (fi) 1996-10-22
CN1149829A (zh) 1997-05-14
SK282594B6 (sk) 2002-10-08
HK1036404A1 (en) 2002-01-04
JPH09512027A (ja) 1997-12-02
ES2152485T3 (es) 2001-02-01
JP3622975B2 (ja) 2005-02-23
IL113433A0 (en) 1995-07-31
EP0978276B1 (de) 2002-09-11
CN1134258C (zh) 2004-01-14
CZ309096A3 (en) 1997-04-16
ATE196845T1 (de) 2000-10-15
SA95160343B1 (ar) 2005-05-04
GB9408117D0 (en) 1994-06-15
ATE223706T1 (de) 2002-09-15
AU2406895A (en) 1995-11-16
BR9507502A (pt) 1997-09-02
DE69528608T2 (de) 2003-06-26
ZA953236B (en) 1995-12-27
DE29522153U1 (de) 2000-04-06
BG62842B1 (bg) 2000-09-29
EP1243267A2 (de) 2002-09-25
HK1050992A1 (en) 2003-07-18
DK1093813T3 (da) 2003-02-17
RO116997B1 (ro) 2001-09-28
EP0978276A3 (de) 2000-04-12
FI964249A7 (fi) 1996-10-22
ATE203161T1 (de) 2001-08-15
EP0758235A1 (de) 1997-02-19
DK0978276T3 (da) 2003-01-20
GR3035031T3 (en) 2001-03-30
PT978276E (pt) 2003-01-31
NZ285080A (en) 1998-05-27
EP1243267A3 (de) 2002-10-30
HK1009936A1 (en) 1999-06-11

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