ES2182754T3 - Procedimiento para preparar comprimidos revestidos con polimero, que comprenden amoxicilina y clavulanato revestidos con un revestimiento polimero acuoso formador de pelicula. - Google Patents

Procedimiento para preparar comprimidos revestidos con polimero, que comprenden amoxicilina y clavulanato revestidos con un revestimiento polimero acuoso formador de pelicula.

Info

Publication number
ES2182754T3
ES2182754T3 ES00204182T ES00204182T ES2182754T3 ES 2182754 T3 ES2182754 T3 ES 2182754T3 ES 00204182 T ES00204182 T ES 00204182T ES 00204182 T ES00204182 T ES 00204182T ES 2182754 T3 ES2182754 T3 ES 2182754T3
Authority
ES
Spain
Prior art keywords
covered
polymer
clavulanate
amoxycline
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00204182T
Other languages
English (en)
Inventor
Creighton Pierce Conley
Nigel Philip Mccreath Davidson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10754044&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2182754(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Application granted granted Critical
Publication of ES2182754T3 publication Critical patent/ES2182754T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Un procedimiento para preparar una formulación de comprimidos que comprende una mezcla compactada de amoxicilina y clavulanato y que tiene un revestimiento de película de polímeros cuyo proceso comprende como paso final revestir con una película el núcleo del comprimido con un revestimiento de película preparado en un sistema de disolvente acuoso.
ES00204182T 1994-04-23 1995-04-19 Procedimiento para preparar comprimidos revestidos con polimero, que comprenden amoxicilina y clavulanato revestidos con un revestimiento polimero acuoso formador de pelicula. Expired - Lifetime ES2182754T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9408117A GB9408117D0 (en) 1994-04-23 1994-04-23 Pharmaceutical formulations

Publications (1)

Publication Number Publication Date
ES2182754T3 true ES2182754T3 (es) 2003-03-16

Family

ID=10754044

Family Applications (4)

Application Number Title Priority Date Filing Date
ES00204182T Expired - Lifetime ES2182754T3 (es) 1994-04-23 1995-04-19 Procedimiento para preparar comprimidos revestidos con polimero, que comprenden amoxicilina y clavulanato revestidos con un revestimiento polimero acuoso formador de pelicula.
ES95917937T Expired - Lifetime ES2161288T3 (es) 1994-04-23 1995-04-19 Comprimido revestido con polimero que comprende amoxicilina y clavulanato.
ES96202848T Expired - Lifetime ES2152485T3 (es) 1994-04-23 1995-04-19 Procedimiento para preparar comprimidos que contienen amoxicilina y clavulanato recubiertos de una pelicula polimerica acuosa.
ES99200891T Expired - Lifetime ES2180251T3 (es) 1994-04-23 1995-04-19 Comprimido revestido con polimero, que contiene amoxicilina y clavulanato.

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES95917937T Expired - Lifetime ES2161288T3 (es) 1994-04-23 1995-04-19 Comprimido revestido con polimero que comprende amoxicilina y clavulanato.
ES96202848T Expired - Lifetime ES2152485T3 (es) 1994-04-23 1995-04-19 Procedimiento para preparar comprimidos que contienen amoxicilina y clavulanato recubiertos de una pelicula polimerica acuosa.
ES99200891T Expired - Lifetime ES2180251T3 (es) 1994-04-23 1995-04-19 Comprimido revestido con polimero, que contiene amoxicilina y clavulanato.

Country Status (35)

Country Link
US (1) US6051255A (es)
EP (5) EP1093813B1 (es)
JP (1) JP3622975B2 (es)
CN (1) CN1134258C (es)
AP (2) AP564A (es)
AT (6) ATE226074T1 (es)
AU (1) AU684949B2 (es)
BG (1) BG62842B1 (es)
BR (1) BR9507502A (es)
CA (1) CA2188496A1 (es)
CZ (2) CZ294168B6 (es)
DE (5) DE69528608T2 (es)
DK (4) DK0978276T3 (es)
DZ (1) DZ1876A1 (es)
ES (4) ES2182754T3 (es)
FI (1) FI964249A7 (es)
GB (1) GB9408117D0 (es)
GR (2) GR3035031T3 (es)
HK (1) HK1050992A1 (es)
HU (1) HU228399B1 (es)
IL (1) IL113433A (es)
MA (1) MA23528A1 (es)
MY (1) MY115351A (es)
NO (1) NO310703B1 (es)
NZ (1) NZ285080A (es)
OA (1) OA10377A (es)
PL (1) PL316966A1 (es)
PT (4) PT978276E (es)
RO (1) RO116997B1 (es)
RU (1) RU2152213C1 (es)
SA (1) SA95160343B1 (es)
SI (1) SI0758235T1 (es)
SK (1) SK282594B6 (es)
WO (1) WO1995028927A1 (es)
ZA (1) ZA953236B (es)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
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GB9407386D0 (en) 1994-04-14 1994-06-08 Smithkline Beecham Plc Pharmaceutical formulation
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DZ2028A1 (fr) * 1995-05-03 2002-10-23 Smithkline Beecham Plc Médicaments destinés au traitement d'infections bactériennes en pédiatrie.
US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
TR199800415T1 (en) * 1995-09-07 1998-05-21 Smithkline Beecham Corporation Farmas�tik form�lasyon.
AT403375B (de) * 1995-11-15 1998-01-26 Biochemie Gmbh Verfahren zur fällung von alkalisalzen der clavulansäure
AT407701B (de) * 1996-08-12 2001-05-25 Biochemie Gmbh Zur direkttablettierung geeignete mischung, die als wesentliche komponenten amoxicillin-trihydrat und das kaliumsalz der clavulansäure enthält und verfahren zur herstellung dieser mischung
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
GB9613470D0 (en) 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
GB9616536D0 (en) * 1996-08-06 1996-09-25 Quadrant Holdings Cambridge Co-amoxiclav dosage form
GB9617780D0 (en) 1996-08-24 1996-10-02 Smithkline Beecham Plc Method of treatment
WO1998034598A2 (en) * 1997-02-07 1998-08-13 Gist-Brocades B.V. Homogeneous granulated formulations for dose sipping technology
CA2280857A1 (en) * 1997-02-14 1998-08-20 Smithkline Beecham Laboratoires Pharmaceutiques Pharmaceutical formulations comprising amoxocyllin and clavulanate
US20030124187A1 (en) * 1997-02-14 2003-07-03 Smithkline Beecham Laboratoires Pharmaceutiques, Pharmaceutical formulations comprising amoxycillin and clavulanate
EP1023065A1 (en) * 1997-08-29 2000-08-02 Dsm N.V. Granules free of excipients
US6326028B1 (en) 1997-10-31 2001-12-04 Monsanto Company Alginate and gellan gum as tablet coating
CA2364342C (en) 1999-04-01 2011-02-01 Dsm N.V. Agglomerates by crystallisation
US7250176B1 (en) 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
US6294199B1 (en) * 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
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US20040038948A1 (en) 1999-12-07 2004-02-26 Uhrich Kathryn E. Therapeutic compositions and methods
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US6756057B2 (en) * 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
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CL2008003230A1 (es) * 2007-11-01 2009-11-27 Sanofi Aventis Healthcare Pty Ltd Composicion de recubrimiento de tableta que comprende polimero celulosico, plastificante, edulcorante y composicion de sabor en polvo la que comprende saborizante asociado con portador solido; fluido de recubrimiento de tableta que comprende dicha composicion; tableta farmaceutica; proceso de preparacion de dicha tableta.
US20120172427A1 (en) * 2009-09-18 2012-07-05 Sanofi (z)-2-cyano-3-hydroxy-but-2-enoic acid-(4'-trifluoromethylphenyl)-amide tablet formulations with improved stability
TR200909787A2 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Üçüncü kuşak bir sefalosporin ve klavulanik asit içeren farmasötik formülasyonlar.
TR201000686A1 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@
TR201000687A1 (tr) 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Aktif madde olarak sefiksim ve klavulanik asit içeren efervesan formülasyonlar
TR201000688A2 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Aktif madde olarak sefaklor ve klavulanik asit içeren efervesan formülasyonlar.
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Also Published As

Publication number Publication date
HK1027024A1 (en) 2001-01-05
AU2406895A (en) 1995-11-16
DE69528204D1 (de) 2002-10-17
BG62842B1 (bg) 2000-09-29
HU228399B1 (en) 2013-03-28
PT978276E (pt) 2003-01-31
BG100933A (en) 1997-07-31
AP564A (en) 1996-11-21
PT758235E (pt) 2001-10-31
EP0978276A2 (en) 2000-02-09
JPH09512027A (ja) 1997-12-02
EP0978276B1 (en) 2002-09-11
EP1243267A2 (en) 2002-09-25
AU684949B2 (en) 1998-01-08
HK1050992A1 (en) 2003-07-18
DE69528204T2 (de) 2003-08-07
EP0761218B1 (en) 2000-10-11
AT5350U1 (de) 2002-06-25
EP0978276A3 (en) 2000-04-12
IL113433A0 (en) 1995-07-31
FI964249A0 (fi) 1996-10-22
CA2188496A1 (en) 1995-11-02
DK1093813T3 (da) 2003-02-17
DE29522153U1 (de) 2000-04-06
EP0758235A1 (en) 1997-02-19
IL113433A (en) 2003-06-24
ES2152485T3 (es) 2001-02-01
ZA953236B (en) 1995-12-27
RO116997B1 (ro) 2001-09-28
CN1149829A (zh) 1997-05-14
HUT76335A (en) 1997-08-28
MY115351A (en) 2003-05-31
DZ1876A1 (fr) 2002-02-17
ATE196845T1 (de) 2000-10-15
DE69521799D1 (de) 2001-08-23
EP1093813A2 (en) 2001-04-25
NO964488L (no) 1996-12-17
MA23528A1 (fr) 1995-12-31
RU2152213C1 (ru) 2000-07-10
GB9408117D0 (en) 1994-06-15
ES2180251T3 (es) 2003-02-01
US6051255A (en) 2000-04-18
SK135496A3 (en) 1997-05-07
PL316966A1 (en) 1997-03-03
CN1134258C (zh) 2004-01-14
EP0758235B1 (en) 2001-07-18
SA95160343B1 (ar) 2005-05-04
GR3036844T3 (en) 2002-01-31
AP9500733A0 (en) 1995-04-30
CZ294168B6 (cs) 2004-10-13
NO964488D0 (no) 1996-10-22
CZ309096A3 (en) 1997-04-16
EP1093813B1 (en) 2002-10-16
HK1009936A1 (en) 1999-06-11
CZ11376U1 (cs) 2001-07-12
SI0758235T1 (en) 2001-10-31
AT5349U1 (de) 2002-06-25
HK1021860A1 (en) 2000-07-07
NZ285080A (en) 1998-05-27
ES2161288T3 (es) 2001-12-01
EP1243267A3 (en) 2002-10-30
ATE223706T1 (de) 2002-09-15
DE69528608T2 (de) 2003-06-26
NO310703B1 (no) 2001-08-20
GR3035031T3 (en) 2001-03-30
FI964249L (fi) 1996-10-22
ATE226074T1 (de) 2002-11-15
HU9602922D0 (en) 1996-12-30
DE69519093D1 (de) 2000-11-16
WO1995028927A1 (en) 1995-11-02
DK0978276T3 (da) 2003-01-20
BR9507502A (pt) 1997-09-02
PT1093813E (pt) 2003-02-28
OA10377A (en) 2001-11-21
FI964249A7 (fi) 1996-10-22
JP3622975B2 (ja) 2005-02-23
ATE203161T1 (de) 2001-08-15
DK0758235T3 (da) 2001-10-29
HK1036404A1 (en) 2002-01-04
DE69528608D1 (de) 2002-11-21
DE69519093T2 (de) 2001-07-19
EP1093813A3 (en) 2001-05-30
DE69521799T2 (de) 2002-06-13
AP9600868A0 (en) 1996-10-31
SK282594B6 (sk) 2002-10-08
PT761218E (pt) 2001-03-30
DK0761218T3 (da) 2000-12-18
EP0761218A1 (en) 1997-03-12

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