ES2182754T3 - Procedimiento para preparar comprimidos revestidos con polimero, que comprenden amoxicilina y clavulanato revestidos con un revestimiento polimero acuoso formador de pelicula. - Google Patents

Procedimiento para preparar comprimidos revestidos con polimero, que comprenden amoxicilina y clavulanato revestidos con un revestimiento polimero acuoso formador de pelicula.

Info

Publication number
ES2182754T3
ES2182754T3 ES00204182T ES00204182T ES2182754T3 ES 2182754 T3 ES2182754 T3 ES 2182754T3 ES 00204182 T ES00204182 T ES 00204182T ES 00204182 T ES00204182 T ES 00204182T ES 2182754 T3 ES2182754 T3 ES 2182754T3
Authority
ES
Spain
Prior art keywords
covered
polymer
clavulanate
amoxycline
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00204182T
Other languages
English (en)
Inventor
Creighton Pierce Conley
Nigel Philip Mccreath Davidson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10754044&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2182754(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Application granted granted Critical
Publication of ES2182754T3 publication Critical patent/ES2182754T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Un procedimiento para preparar una formulación de comprimidos que comprende una mezcla compactada de amoxicilina y clavulanato y que tiene un revestimiento de película de polímeros cuyo proceso comprende como paso final revestir con una película el núcleo del comprimido con un revestimiento de película preparado en un sistema de disolvente acuoso.
ES00204182T 1994-04-23 1995-04-19 Procedimiento para preparar comprimidos revestidos con polimero, que comprenden amoxicilina y clavulanato revestidos con un revestimiento polimero acuoso formador de pelicula. Expired - Lifetime ES2182754T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9408117A GB9408117D0 (en) 1994-04-23 1994-04-23 Pharmaceutical formulations

Publications (1)

Publication Number Publication Date
ES2182754T3 true ES2182754T3 (es) 2003-03-16

Family

ID=10754044

Family Applications (4)

Application Number Title Priority Date Filing Date
ES00204182T Expired - Lifetime ES2182754T3 (es) 1994-04-23 1995-04-19 Procedimiento para preparar comprimidos revestidos con polimero, que comprenden amoxicilina y clavulanato revestidos con un revestimiento polimero acuoso formador de pelicula.
ES95917937T Expired - Lifetime ES2161288T3 (es) 1994-04-23 1995-04-19 Comprimido revestido con polimero que comprende amoxicilina y clavulanato.
ES96202848T Expired - Lifetime ES2152485T3 (es) 1994-04-23 1995-04-19 Procedimiento para preparar comprimidos que contienen amoxicilina y clavulanato recubiertos de una pelicula polimerica acuosa.
ES99200891T Expired - Lifetime ES2180251T3 (es) 1994-04-23 1995-04-19 Comprimido revestido con polimero, que contiene amoxicilina y clavulanato.

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES95917937T Expired - Lifetime ES2161288T3 (es) 1994-04-23 1995-04-19 Comprimido revestido con polimero que comprende amoxicilina y clavulanato.
ES96202848T Expired - Lifetime ES2152485T3 (es) 1994-04-23 1995-04-19 Procedimiento para preparar comprimidos que contienen amoxicilina y clavulanato recubiertos de una pelicula polimerica acuosa.
ES99200891T Expired - Lifetime ES2180251T3 (es) 1994-04-23 1995-04-19 Comprimido revestido con polimero, que contiene amoxicilina y clavulanato.

Country Status (35)

Country Link
US (1) US6051255A (es)
EP (5) EP1243267A3 (es)
JP (1) JP3622975B2 (es)
CN (1) CN1134258C (es)
AP (2) AP564A (es)
AT (6) ATE223706T1 (es)
AU (1) AU684949B2 (es)
BG (1) BG62842B1 (es)
BR (1) BR9507502A (es)
CA (1) CA2188496A1 (es)
CZ (2) CZ11376U1 (es)
DE (5) DE69521799T2 (es)
DK (4) DK0758235T3 (es)
DZ (1) DZ1876A1 (es)
ES (4) ES2182754T3 (es)
FI (1) FI964249A0 (es)
GB (1) GB9408117D0 (es)
GR (2) GR3035031T3 (es)
HK (1) HK1050992A1 (es)
HU (1) HU228399B1 (es)
IL (1) IL113433A (es)
MA (1) MA23528A1 (es)
MY (1) MY115351A (es)
NO (1) NO310703B1 (es)
NZ (1) NZ285080A (es)
OA (1) OA10377A (es)
PL (1) PL316966A1 (es)
PT (4) PT758235E (es)
RO (1) RO116997B1 (es)
RU (1) RU2152213C1 (es)
SA (1) SA95160343B1 (es)
SI (1) SI0758235T1 (es)
SK (1) SK282594B6 (es)
WO (1) WO1995028927A1 (es)
ZA (1) ZA953236B (es)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
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GB9407386D0 (en) 1994-04-14 1994-06-08 Smithkline Beecham Plc Pharmaceutical formulation
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DZ2028A1 (fr) * 1995-05-03 2002-10-23 Smithkline Beecham Plc Médicaments destinés au traitement d'infections bactériennes en pédiatrie.
US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
EP1093812A3 (en) * 1995-09-07 2001-06-06 SmithKline Beecham Corporation Amoxycillin and clavulanate containing pharmaceutical formulation
AT403375B (de) * 1995-11-15 1998-01-26 Biochemie Gmbh Verfahren zur fällung von alkalisalzen der clavulansäure
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
AT407701B (de) * 1996-08-12 2001-05-25 Biochemie Gmbh Zur direkttablettierung geeignete mischung, die als wesentliche komponenten amoxicillin-trihydrat und das kaliumsalz der clavulansäure enthält und verfahren zur herstellung dieser mischung
GB9613470D0 (en) 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
GB9616536D0 (en) * 1996-08-06 1996-09-25 Quadrant Holdings Cambridge Co-amoxiclav dosage form
GB9617780D0 (en) 1996-08-24 1996-10-02 Smithkline Beecham Plc Method of treatment
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US20030124187A1 (en) * 1997-02-14 2003-07-03 Smithkline Beecham Laboratoires Pharmaceutiques, Pharmaceutical formulations comprising amoxycillin and clavulanate
IL131201A (en) * 1997-02-14 2005-06-19 Smithkline Beecham Lab Pharmaceutical formulations comprising amoxycillin and clavulanate
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US6294199B1 (en) * 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
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US7250176B1 (en) * 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
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WO2002030392A2 (en) * 2000-10-12 2002-04-18 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin
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JP2013505213A (ja) * 2009-09-18 2013-02-14 サノフイ 改善された安定性を有する（ｚ）−２−シアノ−３−ヒドロキシ−ブタ−２−エン酸−（４’−トリフルオロメチルフェニル）−アミド錠製剤
TR200909787A2 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Üçüncü kuşak bir sefalosporin ve klavulanik asit içeren farmasötik formülasyonlar.
TR201000688A2 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Aktif madde olarak sefaklor ve klavulanik asit içeren efervesan formülasyonlar.
TR201000686A1 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@
TR201000687A1 (tr) 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Aktif madde olarak sefiksim ve klavulanik asit içeren efervesan formülasyonlar
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Also Published As

Publication number Publication date
AP564A (en) 1996-11-21
HU9602922D0 (en) 1996-12-30
GR3035031T3 (en) 2001-03-30
HK1021860A1 (en) 2000-07-07
NZ285080A (en) 1998-05-27
EP1093813A3 (en) 2001-05-30
HUT76335A (en) 1997-08-28
PT978276E (pt) 2003-01-31
FI964249L (fi) 1996-10-22
DE69521799T2 (de) 2002-06-13
ATE196845T1 (de) 2000-10-15
HK1050992A1 (en) 2003-07-18
EP0978276B1 (en) 2002-09-11
DE29522153U1 (de) 2000-04-06
RO116997B1 (ro) 2001-09-28
DE69528608D1 (de) 2002-11-21
BR9507502A (pt) 1997-09-02
CA2188496A1 (en) 1995-11-02
SK282594B6 (sk) 2002-10-08
AP9500733A0 (en) 1995-04-30
CZ294168B6 (cs) 2004-10-13
EP0761218B1 (en) 2000-10-11
EP0978276A3 (en) 2000-04-12
JPH09512027A (ja) 1997-12-02
CN1149829A (zh) 1997-05-14
GR3036844T3 (en) 2002-01-31
DK0758235T3 (da) 2001-10-29
DK0761218T3 (da) 2000-12-18
CZ11376U1 (cs) 2001-07-12
WO1995028927A1 (en) 1995-11-02
NO964488L (no) 1996-12-17
AU684949B2 (en) 1998-01-08
ATE226074T1 (de) 2002-11-15
DK1093813T3 (da) 2003-02-17
PL316966A1 (en) 1997-03-03
EP1093813B1 (en) 2002-10-16
EP1093813A2 (en) 2001-04-25
HK1027024A1 (en) 2001-01-05
DE69519093D1 (de) 2000-11-16
ATE223706T1 (de) 2002-09-15
SA95160343B1 (ar) 2005-05-04
EP1243267A2 (en) 2002-09-25
PT761218E (pt) 2001-03-30
IL113433A0 (en) 1995-07-31
JP3622975B2 (ja) 2005-02-23
EP1243267A3 (en) 2002-10-30
NO310703B1 (no) 2001-08-20
CZ309096A3 (en) 1997-04-16
US6051255A (en) 2000-04-18
SK135496A3 (en) 1997-05-07
DE69521799D1 (de) 2001-08-23
EP0978276A2 (en) 2000-02-09
BG100933A (en) 1997-07-31
ES2152485T3 (es) 2001-02-01
DK0978276T3 (da) 2003-01-20
HK1036404A1 (en) 2002-01-04
NO964488D0 (no) 1996-10-22
ES2161288T3 (es) 2001-12-01
DZ1876A1 (fr) 2002-02-17
BG62842B1 (bg) 2000-09-29
AU2406895A (en) 1995-11-16
ES2180251T3 (es) 2003-02-01
HK1009936A1 (en) 1999-06-11
AT5350U1 (de) 2002-06-25
DE69528204D1 (de) 2002-10-17
FI964249A7 (fi) 1996-10-22
CN1134258C (zh) 2004-01-14
RU2152213C1 (ru) 2000-07-10
AP9600868A0 (en) 1996-10-31
OA10377A (en) 2001-11-21
EP0758235B1 (en) 2001-07-18
HU228399B1 (en) 2013-03-28
DE69519093T2 (de) 2001-07-19
SI0758235T1 (en) 2001-10-31
MA23528A1 (fr) 1995-12-31
MY115351A (en) 2003-05-31
ZA953236B (en) 1995-12-27
AT5349U1 (de) 2002-06-25
DE69528204T2 (de) 2003-08-07
EP0758235A1 (en) 1997-02-19
GB9408117D0 (en) 1994-06-15
PT758235E (pt) 2001-10-31
DE69528608T2 (de) 2003-06-26
ATE203161T1 (de) 2001-08-15
IL113433A (en) 2003-06-24
PT1093813E (pt) 2003-02-28
EP0761218A1 (en) 1997-03-12
FI964249A0 (fi) 1996-10-22

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