IL115105A - Topical ketoconazole emulsions lacking sodium sulfite - Google Patents

Topical ketoconazole emulsions lacking sodium sulfite

Info

Publication number: IL115105A
Authority: IL; Israel
Prior art keywords: sodium sulfite; emulsions; pct; ketoconazole; lacking sodium
Prior art date: 1994-09-01

Application number

IL11510595A

Other languages

English (en)

Other versions

IL115105A0 (en

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-01

Filing date

1995-08-30

Publication date

1999-12-22

1995-08-30 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1995-12-08 Publication of IL115105A0 publication Critical patent/IL115105A0/xx

1999-12-22 Publication of IL115105A publication Critical patent/IL115105A/xx

Links

239000000839 emulsion Substances 0.000 title abstract 4
GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 title abstract 4
XMAYWYJOQHXEEK-OZXSUGGESA-N (2R,4S)-ketoconazole Chemical compound C1CN(C(=O)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2C=NC=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 XMAYWYJOQHXEEK-OZXSUGGESA-N 0.000 title abstract 2
229960004125 ketoconazole Drugs 0.000 title abstract 2
235000010265 sodium sulphite Nutrition 0.000 title abstract 2
230000000699 topical effect Effects 0.000 title 1
239000003963 antioxidant agent Substances 0.000 abstract 1
230000003078 antioxidant effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Oncology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Cosmetics (AREA)

IL11510595A 1994-09-01 1995-08-30 Topical ketoconazole emulsions lacking sodium sulfite IL115105A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP94202505		1994-09-01

Publications (2)

Publication Number	Publication Date
IL115105A0 IL115105A0 (en)	1995-12-08
IL115105A true IL115105A (en)	1999-12-22

Family

ID=8217156

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11510595A IL115105A (en)	1994-09-01	1995-08-30	Topical ketoconazole emulsions lacking sodium sulfite

Country Status (19)

Country	Link
US (1)	US5854246A (de)
EP (1)	EP0778771B1 (de)
JP (1)	JP3959110B2 (de)
KR (1)	KR100381701B1 (de)
CN (1)	CN1098074C (de)
AT (1)	ATE291917T1 (de)
AU (1)	AU698065B2 (de)
CA (1)	CA2198240C (de)
DE (1)	DE69534120T2 (de)
DK (1)	DK0778771T3 (de)
ES (1)	ES2240977T3 (de)
IL (1)	IL115105A (de)
MX (1)	MX9701397A (de)
MY (1)	MY115980A (de)
PT (1)	PT778771E (de)
SI (1)	SI0778771T1 (de)
TW (1)	TW460296B (de)
WO (1)	WO1996006613A1 (de)
ZA (1)	ZA957329B (de)

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SE9604610D0 (sv) *	1996-12-16	1996-12-16	Noviscens Ab	Medical composition
AU7484198A (en) *	1997-05-12	1998-12-08	Sage Pharmaceuticals, Inc.	Topical spray for burn treatment and anti-infection
AU734429B2 (en) *	1997-05-14	2001-06-14	Galen (Chemicals) Limited	Topical compositions
AUPO983897A0 (en)	1997-10-17	1997-11-06	Soltec Research Pty Ltd	Topical antifungal composition
RU2120305C1 (ru) *	1997-11-27	1998-10-20	Открытое акционерное общество Химико-фармацевтический комбинат "Акрихин"	Фармацевтический состав, обладающий противогрибковой активностью, и способ его получения
US5980904A (en) *	1998-11-18	1999-11-09	Amway Corporation	Skin whitening composition containing bearberry extract and a reducing agent
US6238683B1 (en) *	1998-12-04	2001-05-29	Johnson & Johnson Consumer Companies, Inc.	Anhydrous topical skin preparations
CN1173703C (zh) *	1999-04-23	2004-11-03	里奥药物制品有限公司	药物组合物
JP2005537244A (ja) *	2002-06-28	2005-12-08	ナステック・ファーマシューティカル・カンパニー・インコーポレーテッド	療法化合物の粘膜搬送を増進させるための、上皮接合部接着分子の生理機能を調節する組成物および方法
IL152486A0 (en)	2002-10-25	2003-05-29	Meir Eini	Alcohol-free cosmetic and pharmaceutical foam carrier
US7700076B2 (en) *	2002-10-25	2010-04-20	Foamix, Ltd.	Penetrating pharmaceutical foam
US10117812B2 (en)	2002-10-25	2018-11-06	Foamix Pharmaceuticals Ltd.	Foamable composition combining a polar solvent and a hydrophobic carrier
US9265725B2 (en)	2002-10-25	2016-02-23	Foamix Pharmaceuticals Ltd.	Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US8636982B2 (en)	2007-08-07	2014-01-28	Foamix Ltd.	Wax foamable vehicle and pharmaceutical compositions thereof
WO2009072007A2 (en)	2007-12-07	2009-06-11	Foamix Ltd.	Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
WO2010109422A1 (en) *	2009-03-25	2010-09-30	Sulur Subramaniam Vanangamudi	A medicinal cream for diaper rash and a process to make it
BRPI1006729B1 (pt) *	2009-04-13	2021-10-05	Sulur Subramaniam Vanangamudi	Creme medicinal de ácido fusídico preparado utilizando fusidato de sódio e incorporando um biopolímero e seu processo de preparação
BG66048B1 (bg) *	2009-04-21	2010-12-30	Емил ЯМАЛИЕВ	Състав и метод за получаване на козметичен противопърхутен гел
US20120087872A1 (en)	2009-04-28	2012-04-12	Foamix Ltd.	Foamable Vehicles and Pharmaceutical Compositions Comprising Aprotic Polar Solvents and Uses Thereof
WO2011013009A2 (en)	2009-07-29	2011-02-03	Foamix Ltd.	Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769677A1 (en)	2009-07-29	2011-02-03	Foamix Ltd.	Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
AU2010302350B2 (en)	2009-10-02	2015-06-18	Journey Medical Corporation	Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
US9849142B2 (en)	2009-10-02	2017-12-26	Foamix Pharmaceuticals Ltd.	Methods for accelerated return of skin integrity and for the treatment of impetigo
US12661407B2 (en)	2010-04-08	2026-06-23	Journey Medical Corporation	Compositions, gels and foams with rheology modulators and uses thereof
CN102018667B (zh) *	2010-10-29	2012-08-08	杭州雷布科技有限公司	一种咪唑类抗真菌皮肤擦拭剂及其制备方法
EP2723452A2 (de)	2011-06-22	2014-04-30	Vyome Biosciences Pvt Ltd	Konjugatbasierte antimykotische und antibakterielle prodrugs
US8530409B1 (en) *	2012-06-12	2013-09-10	Dipexium Pharmaceuticals LLC	Stable pexiganan formulation
WO2014195872A1 (en)	2013-06-04	2014-12-11	Vyome Biosciences Pvt. Ltd.	Coated particles and compositions comprising same
MX2020012139A (es)	2016-09-08	2021-01-29	Vyne Pharmaceuticals Inc	Composiciones y metodos para tratar rosacea y acne.
CN110876756A (zh) *	2019-12-17	2020-03-13	罗香英	用于治疗灰指甲的药膏
CN121197036A (zh) *	2025-11-11	2025-12-26	江西众泽源医药科技有限公司	一种复方酮康唑乳膏及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US456935A (en) *		1891-08-04		Axle-cutter
US4144346A (en) *	1977-01-31	1979-03-13	Janssen Pharmaceutica N.V.	Novel 1-(1,3-dioxolan-2-ylmethyl)-1H-imidazoles
US4942162A (en) *	1982-03-31	1990-07-17	University Of Tennessee Research Corporation	Topical treatment of seborrheic dermatitis with ketoconazole
US4569935A (en) *	1983-03-17	1986-02-11	University Of Tennessee Research Corp.	Topical treatment of psoriasis with imidazole antibiotics
JPH0774145B2 (ja) *	1986-12-15	1995-08-09	株式会社資生堂	結晶性薬物含有乳化組成物
US4976953A (en) *	1987-03-06	1990-12-11	The Procter & Gamble Company	Skin conditioning/cleansing compositions containing propoxylated glycerol derivatives
US5002974A (en) *	1988-04-04	1991-03-26	Warner-Lambert Co.	Anesthetic/skin moisturizing composition and method of preparing same
GB8910069D0 (en) *	1989-05-03	1989-06-21	Janssen Pharmaceutica Nv	Method of topically treating acne vulgaris
GB9014221D0 (en) *	1990-06-26	1990-08-15	Janssen Pharmaceutica Nv	Method of treating alopecia
US5215839A (en) *	1991-12-23	1993-06-01	Xerox Corporation	Method and system for reducing surface reflections from an electrophotographic imaging member
US5456851A (en) *	1994-04-07	1995-10-10	Johnson & Johnson Consumer Products, Inc.	Ketoconazole shampoo containing butylated hydroxytoluene or butylated hydroxyanisole

1995
- 1995-07-07 TW TW084107005A patent/TW460296B/zh not_active IP Right Cessation
- 1995-08-25 AT AT95931931T patent/ATE291917T1/de active
- 1995-08-25 CN CN95194847A patent/CN1098074C/zh not_active Expired - Lifetime
- 1995-08-25 AU AU35183/95A patent/AU698065B2/en not_active Expired
- 1995-08-25 JP JP50847696A patent/JP3959110B2/ja not_active Expired - Lifetime
- 1995-08-25 SI SI9530718T patent/SI0778771T1/xx unknown
- 1995-08-25 WO PCT/EP1995/003366 patent/WO1996006613A1/en not_active Ceased
- 1995-08-25 CA CA002198240A patent/CA2198240C/en not_active Expired - Lifetime
- 1995-08-25 DE DE69534120T patent/DE69534120T2/de not_active Expired - Lifetime
- 1995-08-25 KR KR1019970701169A patent/KR100381701B1/ko not_active Expired - Lifetime
- 1995-08-25 US US08/793,359 patent/US5854246A/en not_active Expired - Lifetime
- 1995-08-25 PT PT95931931T patent/PT778771E/pt unknown
- 1995-08-25 DK DK95931931T patent/DK0778771T3/da active
- 1995-08-25 MX MX9701397A patent/MX9701397A/es unknown
- 1995-08-25 EP EP95931931A patent/EP0778771B1/de not_active Expired - Lifetime
- 1995-08-25 ES ES95931931T patent/ES2240977T3/es not_active Expired - Lifetime
- 1995-08-30 IL IL11510595A patent/IL115105A/xx not_active IP Right Cessation
- 1995-08-31 ZA ZA957329A patent/ZA957329B/xx unknown
- 1995-09-01 MY MYPI95002592A patent/MY115980A/en unknown

Also Published As

Publication number	Publication date
DE69534120T2 (de)	2006-01-26
DE69534120D1 (de)	2005-05-04
CA2198240C (en)	2007-04-10
EP0778771A1 (de)	1997-06-18
US5854246A (en)	1998-12-29
KR100381701B1 (ko)	2003-09-26
WO1996006613A1 (en)	1996-03-07
PT778771E (pt)	2005-08-31
AU3518395A (en)	1996-03-22
JPH10505346A (ja)	1998-05-26
CN1098074C (zh)	2003-01-08
EP0778771B1 (de)	2005-03-30
CA2198240A1 (en)	1996-03-07
ATE291917T1 (de)	2005-04-15
IL115105A0 (en)	1995-12-08
TW460296B (en)	2001-10-21
AU698065B2 (en)	1998-10-22
CN1156407A (zh)	1997-08-06
JP3959110B2 (ja)	2007-08-15
SI0778771T1 (en)	2005-10-31
MY115980A (en)	2003-10-31
DK0778771T3 (da)	2005-07-25
MX9701397A (es)	1997-05-31
ES2240977T3 (es)	2005-10-16
ZA957329B (en)	1997-02-28

Legal Events

Date	Code	Title
2000-06-01	FF	Patent granted
2000-08-31	KB	Patent renewed
2001-10-31	KB	Patent renewed
2005-11-20	KB	Patent renewed
2013-07-31	KB	Patent renewed
2016-04-21	EXP	Patent expired

Publication	Publication Date	Title
ZA957329B (en)	1997-02-28	Topical ketoconazole emulsions
DK0772604T3 (da)	1999-11-01	Trialzolforbindelser og deres anvendelse som dopamin-D3-ligander
TW263499B (de)	1995-11-21
HRP990167B1 (en)	2002-08-31	Sulphinic acid derivatives, method for producing them, and their use
AU3115395A (en)	1996-02-22	Dihydrobenzofuranes
BG102425A (en)	1999-06-30	(methylsulphonyl)phenyl-2-(5h)-furanons as cyclooxygenase-2-inhibitors
BG102259A (en)	1998-09-30	Compostions with controlled paroxetine release
GR3022510T3 (en)	1997-05-31	Lyospheres comprising gonadotropin
EP0917873A4 (de)	2003-06-11	Augentropfen
NO930232D0 (no)	1993-01-22	Vateritt og fremstillingsmetode
AU3397795A (en)	1996-03-29	A method for production of ethyl alcohol
DE69703796D1 (de)	2001-02-01	N-bis- oder n-tris-[(1,2-dicarboxy-ethoxy)-ethyl]-amin-derivate und herstellung und anwendung derselben
IT1293777B1 (it)	1999-03-10	Processo per la preparazione di tetraazamacrocicli
BG102213A (en)	1998-08-31	Endoparasiticidic composition based on didepsipeptides, new didepsipeptides and method for their preparation
HU9700024D0 (en)	1997-02-28	Imidazopyridin-azolidinones
GR3036220T3 (en)	2001-10-31	Process for reducing sulfur and vat dyes
MX9603087A (es)	1997-01-31	Procedimiento para la obtencion de aminocarboniltriazolinonas substituidas.
SE9404438D0 (sv)	1994-12-21	New process
ES2140683T3 (es)	2000-03-01	Procedimiento para preparar compuestos de benzopirano.
MX9603450A (es)	1997-03-29	Procedimiento para la obtencion de aminotriazolinas substituidas.
ATE103606T1 (de)	1994-04-15	Verfahren zur herstellung von sulfinylpristinamycin iib.
MY132066A (en)	2007-09-28	Pyrrolidinylmethylindole salt.
ZA200103910B (en)	2002-07-31	1,4-Diaryl-2-fluoro-1-buten-3-ol compounds and their use in the preparation of 1,4-diaryl-2-fluoro-1,3-butadiene and 1,4-diaryl-2-fluoro-2-butene compounds.
PL322847A1 (en)	1998-02-16	Condensed b-carbolins