IL121969A - 10,13,15-trioxatricyclo¬9.2.1.1.9.6¾-pentadecanone derivatives their preparation and pharmaceutical compositions containing these compounds - Google Patents

10,13,15-trioxatricyclo¬9.2.1.1.9.6¾-pentadecanone derivatives their preparation and pharmaceutical compositions containing these compounds

Info

Publication number: IL121969A
Authority: IL; Israel
Prior art keywords: trioxatricyclo; pentadecanone; derivatives; compounds; preparation
Prior art date: 1996-10-24

Application number

IL12196997A

Other languages

English (en)

Other versions

IL121969A0 (en

Original Assignee

Solvay Pharm Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-10-24

Filing date

1997-10-14

Publication date

2000-06-29

1997-10-14 Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh

1998-03-10 Publication of IL121969A0 publication Critical patent/IL121969A0/xx

2000-06-29 Publication of IL121969A publication Critical patent/IL121969A/xx

Links

150000001875 compounds Chemical class 0.000 title 1
QCJWNUNXTZOXCF-UHFFFAOYSA-N pentadecan-4-one Chemical class CCCCCCCCCCCC(=O)CCC QCJWNUNXTZOXCF-UHFFFAOYSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Genetics & Genomics (AREA)
Public Health (AREA)
Biotechnology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Medicinal Preparation (AREA)

IL12196997A 1996-10-24 1997-10-14 10,13,15-trioxatricyclo¬9.2.1.1.9.6¾-pentadecanone derivatives their preparation and pharmaceutical compositions containing these compounds IL121969A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19644195A DE19644195A1 (de)	1996-10-24	1996-10-24	10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (2)

Publication Number	Publication Date
IL121969A0 IL121969A0 (en)	1998-03-10
IL121969A true IL121969A (en)	2000-06-29

Family

ID=7809858

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12196997A IL121969A (en)	1996-10-24	1997-10-14	10,13,15-trioxatricyclo¬9.2.1.1.9.6¾-pentadecanone derivatives their preparation and pharmaceutical compositions containing these compounds

Country Status (26)

Country	Link
US (1)	US5912235A (pl)
EP (1)	EP0838469B1 (pl)
JP (1)	JP4175682B2 (pl)
KR (1)	KR100466495B1 (pl)
CN (1)	CN1093133C (pl)
AR (1)	AR009809A1 (pl)
AT (1)	ATE211745T1 (pl)
AU (1)	AU726092B2 (pl)
BR (2)	BR9705157A (pl)
CA (1)	CA2219311C (pl)
CZ (1)	CZ291768B6 (pl)
DE (2)	DE19644195A1 (pl)
DK (1)	DK0838469T3 (pl)
DZ (1)	DZ2322A1 (pl)
ES (1)	ES2170318T3 (pl)
HU (1)	HU222540B1 (pl)
IL (1)	IL121969A (pl)
MX (1)	MX9707974A (pl)
NO (1)	NO308362B1 (pl)
NZ (1)	NZ328979A (pl)
PL (1)	PL184693B1 (pl)
PT (1)	PT838469E (pl)
RU (1)	RU2181727C2 (pl)
SK (1)	SK283114B6 (pl)
UA (1)	UA44310C2 (pl)
ZA (1)	ZA979059B (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU4968997A (en) *	1996-11-26	1998-06-22	Chugai Seiyaku Kabushiki Kaisha	13-membered ring macrolide compounds, medicine containing the same, and process for producing the same
ATE321770T1 (de) *	2000-08-17	2006-04-15	Kitasato Inst	Pseudoerythromycin-derivate
JP2003007917A (ja) *	2001-06-19	2003-01-10	Sanyo Electric Co Ltd	回路装置の製造方法
US6986882B2 (en) *	2002-01-17	2006-01-17	Astrazeneca Ab	Therapy for functional dyspepsia
DK1633774T3 (da)	2003-06-18	2010-05-25	Tranzyme Pharma Inc	Makrocykliske motilinreceptorantagonister
GB0611907D0 (en)	2006-06-15	2006-07-26	Glaxo Group Ltd	Compounds
EP1902022A1 (en)	2005-07-12	2008-03-26	Glaxo Group Limited	Piperazine heteroaryl derivates as gpr38 agonists
SI1907374T1 (sl) *	2005-07-26	2012-11-30	Glaxo Group Ltd	Derivati benzilpiperazina uporabni za zdravljenje gastrointestinalnih motenj
JP2009518396A (ja) *	2005-12-08	2009-05-07	ファイザー・インク	エリスロマイシン化合物の３’−ジメチルアミノ基を脱メチルする方法
MX2009000110A (es)	2006-06-28	2009-01-23	Glaxo Group Ltd	Derivados de piperazinilo utiles en el tratamiento de enfermedades mediadas por el receptor grp38.
EP2431380A3 (en)	2006-09-11	2013-07-03	Tranzyme Pharma, Inc.	Macrocyclic antagonist of the motilin receptor for treatment of gastrointestinal dysmotility disorders
CA2670482C (en) *	2006-12-05	2011-10-11	Pfizer Inc.	Motilide polymorphs
KR101575703B1 (ko)	2009-02-27	2015-12-10	라퀄리아 파마 인코포레이티드	모틸린 수용체에 대해 작용제 활성을 가진 옥시인돌 유도체
TWI662967B (zh) *	2013-03-25	2019-06-21	日商志瑞亞新藥工業股份有限公司	食後期之胃運動亢進劑

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3725385A (en) *	1970-11-02	1973-04-03	Abbott Lab	Process for the demethylation of 3-amino macrolides
US5106961A (en) *	1987-05-26	1992-04-21	Eli Lilly And Company	Erythromycin ring-contracted derivatives
US4920102A (en) *	1988-04-18	1990-04-24	Eli Lilly And Company	Method for treating gastrointestinal disorders
DE4200145A1 (de) *	1992-01-07	1993-07-08	Kali Chemie Pharma Gmbh	7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

1996
- 1996-10-24 DE DE19644195A patent/DE19644195A1/de not_active Withdrawn
1997
- 1997-09-23 AR ARP970104375A patent/AR009809A1/es active IP Right Grant
- 1997-09-29 DZ DZ970172A patent/DZ2322A1/xx active
- 1997-10-01 CZ CZ19973106A patent/CZ291768B6/cs not_active IP Right Cessation
- 1997-10-07 KR KR1019970051470A patent/KR100466495B1/ko not_active Expired - Fee Related
- 1997-10-09 ZA ZA9709059A patent/ZA979059B/xx unknown
- 1997-10-14 IL IL12196997A patent/IL121969A/xx not_active IP Right Cessation
- 1997-10-16 MX MX9707974A patent/MX9707974A/es not_active IP Right Cessation
- 1997-10-17 AT AT97118000T patent/ATE211745T1/de not_active IP Right Cessation
- 1997-10-17 SK SK1419-97A patent/SK283114B6/sk not_active IP Right Cessation
- 1997-10-17 HU HU9701660A patent/HU222540B1/hu not_active IP Right Cessation
- 1997-10-17 DK DK97118000T patent/DK0838469T3/da active
- 1997-10-17 DE DE59705964T patent/DE59705964D1/de not_active Expired - Fee Related
- 1997-10-17 ES ES97118000T patent/ES2170318T3/es not_active Expired - Lifetime
- 1997-10-17 PT PT97118000T patent/PT838469E/pt unknown
- 1997-10-17 EP EP97118000A patent/EP0838469B1/de not_active Expired - Lifetime
- 1997-10-17 NZ NZ328979A patent/NZ328979A/xx unknown
- 1997-10-21 US US08/954,891 patent/US5912235A/en not_active Expired - Lifetime
- 1997-10-22 CN CN97121157A patent/CN1093133C/zh not_active Expired - Fee Related
- 1997-10-22 AU AU42788/97A patent/AU726092B2/en not_active Ceased
- 1997-10-22 JP JP28986197A patent/JP4175682B2/ja not_active Expired - Fee Related
- 1997-10-23 UA UA97105178A patent/UA44310C2/uk unknown
- 1997-10-23 RU RU97117347/04A patent/RU2181727C2/ru not_active IP Right Cessation
- 1997-10-23 PL PL97322802A patent/PL184693B1/pl not_active IP Right Cessation
- 1997-10-24 BR BR9705157-8A patent/BR9705157A/pt not_active Application Discontinuation
- 1997-10-24 NO NO974934A patent/NO308362B1/no not_active IP Right Cessation
- 1997-10-24 CA CA002219311A patent/CA2219311C/en not_active Expired - Fee Related
- 1997-10-24 BR BR9705143-8A patent/BR9705143A/pt active Search and Examination

Also Published As

Publication number	Publication date
SK283114B6 (sk)	2003-02-04
PL184693B1 (pl)	2002-12-31
DK0838469T3 (da)	2002-03-18
DE59705964D1 (de)	2002-02-14
BR9705143A (pt)	2000-12-12
UA44310C2 (uk)	2002-02-15
EP0838469B1 (de)	2002-01-09
CZ291768B6 (cs)	2003-05-14
EP0838469A1 (de)	1998-04-29
MX9707974A (es)	1998-04-30
NZ328979A (en)	1998-10-28
CN1186808A (zh)	1998-07-08
ZA979059B (en)	1998-05-07
ATE211745T1 (de)	2002-01-15
KR19980032626A (ko)	1998-07-25
HK1010885A1 (en)	1999-07-02
HU222540B1 (hu)	2003-08-28
DE19644195A1 (de)	1998-04-30
ES2170318T3 (es)	2002-08-01
IL121969A0 (en)	1998-03-10
CA2219311C (en)	2007-09-04
US5912235A (en)	1999-06-15
AR009809A1 (es)	2000-05-03
HUP9701660A2 (hu)	1998-05-28
DZ2322A1 (fr)	2002-12-28
NO974934D0 (no)	1997-10-24
KR100466495B1 (ko)	2005-05-27
CA2219311A1 (en)	1998-04-24
PL322802A1 (en)	1998-04-27
HUP9701660A3 (en)	1998-08-28
HU9701660D0 (en)	1997-12-29
BR9705157A (pt)	1999-09-28
NO974934L (no)	1998-04-27
CZ310697A3 (cs)	1998-06-17
JP4175682B2 (ja)	2008-11-05
AU726092B2 (en)	2000-11-02
NO308362B1 (no)	2000-09-04
AU4278897A (en)	1998-04-30
CN1093133C (zh)	2002-10-23
PT838469E (pt)	2002-05-31
JPH10130297A (ja)	1998-05-19
SK141997A3 (en)	1998-05-06
RU2181727C2 (ru)	2002-04-27

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Legal Events

Date	Code	Title
2000-11-21	FF	Patent granted
2004-01-04	KB	Patent renewed
2007-12-03	KB	Patent renewed
2012-10-31	MM9K	Patent not in force due to non-payment of renewal fees