IL122123A - Estrogen agonists / antagonists, their pharmaceutical preparations and their use in the preparation of drugs for the treatment of atherosclerosis - Google Patents

Estrogen agonists / antagonists, their pharmaceutical preparations and their use in the preparation of drugs for the treatment of atherosclerosis

Info

Publication number: IL122123A
Authority: IL; Israel
Prior art keywords: phenyl; compound; recited; independently selected; formula
Prior art date: 1996-11-15

Application number

IL12212397A

Other languages

English (en)

Hebrew (he)

Other versions

IL122123A0 (en

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-11-15

Filing date

1997-11-06

Publication date

2001-07-24

1997-11-06 Application filed by Pfizer filed Critical Pfizer

1998-04-05 Publication of IL122123A0 publication Critical patent/IL122123A0/xx

2001-07-24 Publication of IL122123A publication Critical patent/IL122123A/en

Links

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Classifications

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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47J—KITCHEN EQUIPMENT; COFFEE MILLS; SPICE MILLS; APPARATUS FOR MAKING BEVERAGES
- A47J47/00—Kitchen containers, stands or the like, not provided for in other groups of this subclass; Cutting-boards, e.g. for bread
- A47J47/02—Closed containers for foodstuffs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Food Science & Technology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Plant Substances (AREA)
Steroid Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Indole Compounds (AREA)

IL12212397A 1996-11-15 1997-11-06 Estrogen agonists / antagonists, their pharmaceutical preparations and their use in the preparation of drugs for the treatment of atherosclerosis IL122123A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US3127396P	1996-11-15	1996-11-15

Publications (2)

Publication Number	Publication Date
IL122123A0 IL122123A0 (en)	1998-04-05
IL122123A true IL122123A (en)	2001-07-24

Family

ID=21858549

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12212397A IL122123A (en)	1996-11-15	1997-11-06	Estrogen agonists / antagonists, their pharmaceutical preparations and their use in the preparation of drugs for the treatment of atherosclerosis

Country Status (17)

Country	Link
US (1)	US6034102A (da)
EP (1)	EP0842661B1 (da)
JP (1)	JP3287793B2 (da)
KR (1)	KR100367793B1 (da)
AT (1)	ATE202702T1 (da)
AU (1)	AU740378B2 (da)
CA (1)	CA2221114C (da)
DE (1)	DE69705480T2 (da)
DK (1)	DK0842661T3 (da)
ES (1)	ES2158452T3 (da)
GR (1)	GR3036455T3 (da)
HU (1)	HU223942B1 (da)
IL (1)	IL122123A (da)
MY (1)	MY114586A (da)
NZ (1)	NZ329174A (da)
PT (1)	PT842661E (da)
ZA (1)	ZA9710292B (da)

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JP2003521468A (ja)	1999-03-17	2003-07-15	シグナルファーマシューティカルズ，インコーポレイテッド	エストロゲンレセプタを変調させるための化合物及び方法
CO5170459A1 (es) *	1999-06-01	2002-06-27	Pfizer Prod Inc	Terapia transdermica con agonistas-antagonistas de estrogenos len-ol, administrados mediante medios transdermicos
EP1113007A1 (en) *	1999-12-24	2001-07-04	Pfizer Inc.	Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
PL201222B1 (pl) *	2000-06-01	2009-03-31	Watson Pharmaceuticals	Preparat transdermalny lazoksyfenu, urządzenie do podawania lazoksyfenu, oraz zastosowanie lazoksyfenu
US7025968B2 (en)	2000-08-30	2006-04-11	Chemocentryx, Inc.	CMV vaccines
IL145876A0 (en) *	2000-10-17	2002-07-25	Pfizer Prod Inc	Methods and kits for improving vascular health
IL156015A0 (en)	2000-11-24	2003-12-23	Vascular Biogenics Ltd	Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis
WO2002047723A1 (en) *	2000-12-11	2002-06-20	Takeda Chemical Industries, Ltd.	Medicinal compositions having improved water-solubility
CA2437201C (en)	2001-02-02	2008-11-18	Chemocentryx, Inc.	Methods and compositions useful for stimulating an immune response
US6821998B2 (en) *	2001-08-30	2004-11-23	Chemocentryx, Inc.	Arylamines as inhibitors of chemokine binding to US28
CA3204588A1 (en) *	2004-12-08	2006-06-15	Cedars-Sinai Medical Center	Methods for diagnosis and treatment of crohn's disease
WO2008101133A2 (en) *	2007-02-14	2008-08-21	Cedars-Sinai Medical Center	Methods of using genes and genetic variants to predict or diagnose inflammatory bowel disease
WO2008109782A2 (en) *	2007-03-06	2008-09-12	Cedars-Sinai Medical Center	Diagnosis of inflammatory bowel disease in children
EP1874334A4 (en) *	2005-04-15	2011-03-30	Vascular Biogenics Ltd	COMPOSITIONS WITH BETA 2-GLYCOPROTEIN I-PEPTIDES FOR THE PREVENTION AND / OR TREATMENT OF VASCULAR DISEASES
US20100190162A1 (en) *	2007-02-26	2010-07-29	Cedars-Sinai Medical Center	Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease
WO2010039931A2 (en) *	2008-10-01	2010-04-08	Cedars-Sinai Medical Center	Methods of using il17rd and il23-il17 pathway genes to diagnose crohn's disease
US8486640B2 (en)	2007-03-21	2013-07-16	Cedars-Sinai Medical Center	Ileal pouch-anal anastomosis (IPAA) factors in the treatment of inflammatory bowel disease
US20100184050A1 (en) *	2007-04-26	2010-07-22	Cedars-Sinai Medical Center	Diagnosis and treatment of inflammatory bowel disease in the puerto rican population
US20100144903A1 (en) *	2007-05-04	2010-06-10	Cedars-Sinai Medical Center	Methods of diagnosis and treatment of crohn's disease
US20110189685A1 (en) *	2008-10-22	2011-08-04	Cedars-Sinai Medical Center	Methods of using jak3 genetic variants to diagnose and predict crohn's disease
US20110229471A1 (en)	2008-11-26	2011-09-22	Cedars-Sinai Medical Center	Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
WO2010075579A2 (en)	2008-12-24	2010-07-01	Cedars-Sinai Medical Center	Methods of predicting medically refractive ulcerative colitis (mr-uc) requiring colectomy
KR20240122922A (ko)	2013-03-27	2024-08-13	세다르스-신나이 메디칼 센터	Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전
EP3022295A4 (en)	2013-07-19	2017-03-01	Cedars-Sinai Medical Center	Signature of tl1a (tnfsf15) signaling pathway
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JPH04312526A (ja) *	1991-04-09	1992-11-04	Fujisawa Pharmaceut Co Ltd	骨疾患治療剤
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1997
- 1997-10-21 US US08/955,312 patent/US6034102A/en not_active Expired - Fee Related
- 1997-11-05 PT PT97308862T patent/PT842661E/pt unknown
- 1997-11-05 DE DE69705480T patent/DE69705480T2/de not_active Expired - Fee Related
- 1997-11-05 DK DK97308862T patent/DK0842661T3/da active
- 1997-11-05 EP EP97308862A patent/EP0842661B1/en not_active Expired - Lifetime
- 1997-11-05 AT AT97308862T patent/ATE202702T1/de not_active IP Right Cessation
- 1997-11-05 ES ES97308862T patent/ES2158452T3/es not_active Expired - Lifetime
- 1997-11-06 IL IL12212397A patent/IL122123A/en not_active IP Right Cessation
- 1997-11-13 CA CA002221114A patent/CA2221114C/en not_active Expired - Fee Related
- 1997-11-13 NZ NZ329174A patent/NZ329174A/xx unknown
- 1997-11-13 MY MYPI97005407A patent/MY114586A/en unknown
- 1997-11-14 KR KR1019970060003A patent/KR100367793B1/ko not_active Expired - Fee Related
- 1997-11-14 ZA ZA9710292A patent/ZA9710292B/xx unknown
- 1997-11-14 HU HU9702040A patent/HU223942B1/hu not_active IP Right Cessation
- 1997-11-17 JP JP31522797A patent/JP3287793B2/ja not_active Expired - Fee Related
- 1997-11-17 AU AU45237/97A patent/AU740378B2/en not_active Ceased
2001
- 2001-08-27 GR GR20010401305T patent/GR3036455T3/el not_active IP Right Cessation

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KR100367793B1 (ko)	2003-04-21
JPH10147527A (ja)	1998-06-02
AU740378B2 (en)	2001-11-01
KR19980042432A (ko)	1998-08-17
DE69705480D1 (de)	2001-08-09
ZA9710292B (en)	1999-05-17
CA2221114C (en)	2003-10-28
ES2158452T3 (es)	2001-09-01
JP3287793B2 (ja)	2002-06-04
CA2221114A1 (en)	1998-05-15
HU223942B1 (hu)	2005-03-29
MY114586A (en)	2002-11-30
HU9702040D0 (en)	1998-01-28
NZ329174A (en)	2000-10-27
GR3036455T3 (en)	2001-11-30
PT842661E (pt)	2001-10-30
US6034102A (en)	2000-03-07
DK0842661T3 (da)	2001-09-24
IL122123A0 (en)	1998-04-05
DE69705480T2 (de)	2001-10-31
HUP9702040A1 (hu)	2000-11-28
EP0842661A3 (en)	1998-09-02
EP0842661B1 (en)	2001-07-04
ATE202702T1 (de)	2001-07-15
AU4523797A (en)	1998-05-21
EP0842661A2 (en)	1998-05-20

Legal Events

Date	Code	Title
2002-02-10	FF	Patent granted
2002-02-10	KB	Patent renewed
2004-01-04	KB	Patent renewed
2008-01-06	KB	Patent renewed
2012-10-31	MM9K	Patent not in force due to non-payment of renewal fees

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