IL123505A - Sustained release matrix for high-dose insoluble drugs - Google Patents

Sustained release matrix for high-dose insoluble drugs

Info

Publication number
IL123505A
IL123505A IL12350597A IL12350597A IL123505A IL 123505 A IL123505 A IL 123505A IL 12350597 A IL12350597 A IL 12350597A IL 12350597 A IL12350597 A IL 12350597A IL 123505 A IL123505 A IL 123505A
Authority
IL
Israel
Prior art keywords
sustained release
dosage form
ibuprofen
nsaid
weight
Prior art date
Application number
IL12350597A
Other languages
English (en)
Other versions
IL123505A0 (en
Original Assignee
Penwest Pharmaceuticals Compan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Penwest Pharmaceuticals Compan filed Critical Penwest Pharmaceuticals Compan
Publication of IL123505A0 publication Critical patent/IL123505A0/xx
Publication of IL123505A publication Critical patent/IL123505A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL12350597A 1996-07-08 1997-07-08 Sustained release matrix for high-dose insoluble drugs IL123505A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2133596P 1996-07-08 1996-07-08
PCT/US1997/013331 WO1998001117A1 (en) 1996-07-08 1997-07-08 Sustained release matrix for high-dose insoluble drugs

Publications (2)

Publication Number Publication Date
IL123505A0 IL123505A0 (en) 1998-10-30
IL123505A true IL123505A (en) 2004-12-15

Family

ID=21803631

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12350597A IL123505A (en) 1996-07-08 1997-07-08 Sustained release matrix for high-dose insoluble drugs

Country Status (12)

Country Link
US (4) US6093420A (de)
EP (1) EP0859603B1 (de)
JP (1) JP3148256B2 (de)
KR (1) KR100321489B1 (de)
AT (1) ATE417604T1 (de)
AU (1) AU695734B2 (de)
CA (1) CA2231195C (de)
DE (1) DE69739165D1 (de)
ES (1) ES2322405T3 (de)
IL (1) IL123505A (de)
MX (1) MX9801835A (de)
WO (1) WO1998001117A1 (de)

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JPH10511407A (ja) 1998-11-04
AU3818397A (en) 1998-02-02
ES2322405T3 (es) 2009-06-19
MX9801835A (es) 1998-08-30
US6093420A (en) 2000-07-25
DE69739165D1 (de) 2009-01-29
US6245355B1 (en) 2001-06-12
CA2231195A1 (en) 1998-01-15
AU695734B2 (en) 1998-08-20
US20040121012A1 (en) 2004-06-24
KR100321489B1 (ko) 2002-10-09
KR19990044486A (ko) 1999-06-25
WO1998001117A1 (en) 1998-01-15
EP0859603B1 (de) 2008-12-17
CA2231195C (en) 2003-01-21
US20010021392A1 (en) 2001-09-13
ATE417604T1 (de) 2009-01-15
IL123505A0 (en) 1998-10-30
JP3148256B2 (ja) 2001-03-19
US6689386B2 (en) 2004-02-10
EP0859603A4 (de) 2006-05-24
EP0859603A1 (de) 1998-08-26

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