ATE417604T1 - Matrix mit verzögerter freisetzung für hochdosierte unlösliche arzneistoffe - Google Patents

Matrix mit verzögerter freisetzung für hochdosierte unlösliche arzneistoffe

Info

Publication number
ATE417604T1
ATE417604T1 AT97935184T AT97935184T ATE417604T1 AT E417604 T1 ATE417604 T1 AT E417604T1 AT 97935184 T AT97935184 T AT 97935184T AT 97935184 T AT97935184 T AT 97935184T AT E417604 T1 ATE417604 T1 AT E417604T1
Authority
AT
Austria
Prior art keywords
sustained release
high dose
insoluble drugs
release matrix
dose insoluble
Prior art date
Application number
AT97935184T
Other languages
English (en)
Inventor
Anand Baichwal
Original Assignee
Penwest Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Penwest Pharmaceuticals Co filed Critical Penwest Pharmaceuticals Co
Application granted granted Critical
Publication of ATE417604T1 publication Critical patent/ATE417604T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT97935184T 1996-07-08 1997-07-08 Matrix mit verzögerter freisetzung für hochdosierte unlösliche arzneistoffe ATE417604T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2133596P 1996-07-08 1996-07-08

Publications (1)

Publication Number Publication Date
ATE417604T1 true ATE417604T1 (de) 2009-01-15

Family

ID=21803631

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97935184T ATE417604T1 (de) 1996-07-08 1997-07-08 Matrix mit verzögerter freisetzung für hochdosierte unlösliche arzneistoffe

Country Status (12)

Country Link
US (4) US6093420A (de)
EP (1) EP0859603B1 (de)
JP (1) JP3148256B2 (de)
KR (1) KR100321489B1 (de)
AT (1) ATE417604T1 (de)
AU (1) AU695734B2 (de)
CA (1) CA2231195C (de)
DE (1) DE69739165D1 (de)
ES (1) ES2322405T3 (de)
IL (1) IL123505A (de)
MX (1) MX9801835A (de)
WO (1) WO1998001117A1 (de)

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EP0859603A1 (de) 1998-08-26
US6245355B1 (en) 2001-06-12
KR19990044486A (ko) 1999-06-25
US6689386B2 (en) 2004-02-10
CA2231195A1 (en) 1998-01-15
WO1998001117A1 (en) 1998-01-15
EP0859603B1 (de) 2008-12-17
JP3148256B2 (ja) 2001-03-19
CA2231195C (en) 2003-01-21
AU695734B2 (en) 1998-08-20
AU3818397A (en) 1998-02-02
IL123505A0 (en) 1998-10-30
US20040121012A1 (en) 2004-06-24
US6093420A (en) 2000-07-25
JPH10511407A (ja) 1998-11-04
DE69739165D1 (de) 2009-01-29
ES2322405T3 (es) 2009-06-19
EP0859603A4 (de) 2006-05-24
US20010021392A1 (en) 2001-09-13
KR100321489B1 (ko) 2002-10-09
IL123505A (en) 2004-12-15
MX9801835A (es) 1998-08-30

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