IL127685A0 - Fluorine-containing 1,4-disubstituted peperidine derivatives - Google Patents

Fluorine-containing 1,4-disubstituted peperidine derivatives

Info

Publication number
IL127685A0
IL127685A0 IL12768597A IL12768597A IL127685A0 IL 127685 A0 IL127685 A0 IL 127685A0 IL 12768597 A IL12768597 A IL 12768597A IL 12768597 A IL12768597 A IL 12768597A IL 127685 A0 IL127685 A0 IL 127685A0
Authority
IL
Israel
Prior art keywords
peperidine
disubstituted
fluorine
derivatives
peperidine derivatives
Prior art date
Application number
IL12768597A
Other languages
English (en)
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Publication of IL127685A0 publication Critical patent/IL127685A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL12768597A 1996-08-01 1997-07-28 Fluorine-containing 1,4-disubstituted peperidine derivatives IL127685A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP21943696 1996-08-01
JP5397997 1997-02-21
PCT/JP1997/002600 WO1998005641A1 (en) 1996-08-01 1997-07-28 Fluorinated 1,4-disubstituted piperidine derivatives

Publications (1)

Publication Number Publication Date
IL127685A0 true IL127685A0 (en) 1999-10-28

Family

ID=26394715

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12768597A IL127685A0 (en) 1996-08-01 1997-07-28 Fluorine-containing 1,4-disubstituted peperidine derivatives

Country Status (29)

Country Link
US (2) US5948792A (cs)
EP (1) EP0930298B1 (cs)
JP (1) JP3063164B2 (cs)
KR (1) KR20000022214A (cs)
CN (1) CN1226888A (cs)
AR (3) AR008272A1 (cs)
AT (1) ATE229941T1 (cs)
AU (1) AU716050B2 (cs)
BG (1) BG103114A (cs)
BR (1) BR9711108A (cs)
CA (1) CA2261680C (cs)
CO (1) CO4960641A1 (cs)
CZ (1) CZ33199A3 (cs)
DE (1) DE69718026T2 (cs)
EE (1) EE9900038A (cs)
ES (1) ES2188961T3 (cs)
HR (1) HRP970426A2 (cs)
HU (1) HUP9902381A3 (cs)
ID (1) ID17259A (cs)
IL (1) IL127685A0 (cs)
IS (1) IS4960A (cs)
NO (1) NO990472L (cs)
NZ (1) NZ333842A (cs)
PE (1) PE92198A1 (cs)
PL (1) PL331431A1 (cs)
SK (1) SK12299A3 (cs)
TR (2) TR199900204T2 (cs)
WO (1) WO1998005641A1 (cs)
YU (1) YU1299A (cs)

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UA73543C2 (uk) 1999-12-07 2005-08-15 Тераванс, Інк. Похідні сечовини, фармацевтична композиція та застосування похідного при приготуванні лікарського засобу для лікування захворювання, яке опосередковується мускариновим рецептором
JP4782342B2 (ja) * 1999-12-17 2011-09-28 サノフィ−アベンティス フェノキシプロパノールアミン類、それらの製造方法およびそれらを含む医薬組成物
US6403818B1 (en) 2000-02-28 2002-06-11 Eisai Co., Ltd. Process for producing α-hydroxy-carbonyl compound
US6469172B2 (en) 2000-03-08 2002-10-22 Merck & Co., Inc. Process for the preparation of chemical compounds
US6403584B1 (en) * 2000-06-22 2002-06-11 Merck & Co., Inc. Substituted nipecotyl derivatives as inhibitors of cell adhesion
AU2001271027B2 (en) * 2000-07-11 2005-07-07 Msd K.K. Ester derivatives
JP4445704B2 (ja) 2000-12-22 2010-04-07 アルミラル・ソシエダッド・アノニマ キヌクリジンカルバメート誘導体およびｍ３アンダゴニストとしてのそれらの使用
IL156558A0 (en) 2000-12-28 2004-01-04 Almirall Prodesfarma Ag Novel quinuclidine derivatives and medicinal compositions containing the same
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BR0315747A (pt) * 2002-10-29 2005-09-06 Pharmacia & Upjohn Co Llc Compostos de amÈnio quaternário como antagonistas de receptor muscarìnico
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US7232835B2 (en) 2002-12-10 2007-06-19 Ranbaxy Laboratories Limited 3,6-Disubstituted azabicyclo derivatives as muscarinic receptor antagonists
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EP1581522B1 (en) 2002-12-23 2008-02-20 Ranbaxy Laboratories Limited Flavaxate derivatives as muscarinic receptor antagonists
AU2002347552A1 (en) * 2002-12-23 2004-07-14 Ranbaxy Laboratories Limited 1-substituted-3-pyrrolidine derivatives as muscarinic receptor antagonists
US7488748B2 (en) 2003-01-28 2009-02-10 Ranbaxy Laboratories Limited 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
WO2004089898A1 (en) 2003-04-09 2004-10-21 Ranbaxy Laboratories Limited Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists
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EA009387B1 (ru) * 2003-04-11 2007-12-28 Рэнбакси Лабораториз Лимитед Азабициклические производные в качестве антагонистов мускаринового рецептора
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KR101517574B1 (ko) * 2007-09-07 2015-05-07 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 무스카린 수용체 길항제로서 유용한 구아니딘을 함유하는 화합물
KR101247418B1 (ko) * 2007-12-21 2013-03-25 에프. 호프만-라 로슈 아게 항체 제형
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Also Published As

Publication number Publication date
TR199900204T2 (xx) 2000-01-21
ES2188961T3 (es) 2003-07-01
CO4960641A1 (es) 2000-09-25
EE9900038A (et) 1999-08-16
US5948792A (en) 1999-09-07
CZ33199A3 (cs) 1999-07-14
TR200001482T2 (tr) 2000-11-21
ATE229941T1 (de) 2003-01-15
ID17259A (id) 1997-12-11
WO1998005641A1 (en) 1998-02-12
US6040449A (en) 2000-03-21
NO990472D0 (no) 1999-02-01
HUP9902381A3 (en) 2000-06-28
JP3063164B2 (ja) 2000-07-12
CA2261680A1 (en) 1998-02-12
AR008272A1 (es) 1999-12-29
AR016877A2 (es) 2001-08-01
YU1299A (sh) 2002-03-18
EP0930298B1 (en) 2002-12-18
KR20000022214A (ko) 2000-04-25
AR017021A1 (es) 2001-08-22
DE69718026D1 (de) 2003-01-30
AU3635197A (en) 1998-02-25
PL331431A1 (en) 1999-07-19
NZ333842A (en) 2001-05-25
HRP970426A2 (en) 1998-08-31
CN1226888A (zh) 1999-08-25
SK12299A3 (en) 2000-05-16
NO990472L (no) 1999-02-01
AU716050B2 (en) 2000-02-17
IS4960A (is) 1999-01-29
BG103114A (en) 1999-11-30
PE92198A1 (es) 1999-01-09
DE69718026T2 (de) 2003-07-10
BR9711108A (pt) 1999-08-17
EP0930298A4 (en) 2000-06-07
CA2261680C (en) 2005-03-08
EP0930298A1 (en) 1999-07-21
HUP9902381A2 (hu) 1999-11-29

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