IL127773A0 - Saccharide conjugates and pharmaceutical compositions comprising them - Google Patents

Saccharide conjugates and pharmaceutical compositions comprising them

Info

Publication number: IL127773A0
Authority: IL; Israel
Prior art keywords: saccharide; aids; residue; conjugates; sac
Prior art date: 1998-12-28

Application number

IL12777398A

Other languages

English (en)

Original Assignee

Yeda Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-28

Filing date

1998-12-28

Publication date

1999-10-28

1998-12-28 Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev

1998-12-28 Priority to IL12777398A priority Critical patent/IL127773A0/xx

1999-10-28 Publication of IL127773A0 publication Critical patent/IL127773A0/xx

1999-12-28 Priority to DE69930412T priority patent/DE69930412T2/de

1999-12-28 Priority to IL14399599A priority patent/IL143995A0/xx

1999-12-28 Priority to US09/869,437 priority patent/US6642365B1/en

1999-12-28 Priority to PCT/IL1999/000704 priority patent/WO2000039139A1/en

1999-12-28 Priority to AU17956/00A priority patent/AU1795600A/en

1999-12-28 Priority to HK02102642.6A priority patent/HK1042904A1/zh

1999-12-28 Priority to JP2000591050A priority patent/JP2003525859A/ja

1999-12-28 Priority to EP99961263A priority patent/EP1140958B1/de

1999-12-28 Priority to AT99961263T priority patent/ATE320439T1/de

2001-06-26 Priority to IL143995A priority patent/IL143995A/en

Links

150000001720 carbohydrates Chemical class 0.000 title abstract 3
239000008194 pharmaceutical composition Substances 0.000 title 1
208000030507 AIDS Diseases 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
150000002772 monosaccharides Chemical class 0.000 abstract 2
150000002482 oligosaccharides Polymers 0.000 abstract 2
125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
239000004475 Arginine Substances 0.000 abstract 1
229930182566 Gentamicin Natural products 0.000 abstract 1
CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 abstract 1
208000031886 HIV Infections Diseases 0.000 abstract 1
208000037357 HIV infectious disease Diseases 0.000 abstract 1
208000007766 Kaposi sarcoma Diseases 0.000 abstract 1
229930193140 Neomycin Natural products 0.000 abstract 1
229940126574 aminoglycoside antibiotic Drugs 0.000 abstract 1
239000002647 aminoglycoside antibiotic agent Substances 0.000 abstract 1
230000000798 anti-retroviral effect Effects 0.000 abstract 1
230000000840 anti-viral effect Effects 0.000 abstract 1
125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
229940042399 direct acting antivirals protease inhibitors Drugs 0.000 abstract 1
208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
-1 hydroxy, amino Chemical group 0.000 abstract 1
229960000318 kanamycin Drugs 0.000 abstract 1
229930027917 kanamycin Natural products 0.000 abstract 1
SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 abstract 1
229930182823 kanamycin A Natural products 0.000 abstract 1
229960004927 neomycin Drugs 0.000 abstract 1
229920001542 oligosaccharide Polymers 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
239000000137 peptide hydrolase inhibitor Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Virology (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Oncology (AREA)
Crystallography & Structural Chemistry (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Peptides Or Proteins (AREA)

IL12777398A 1998-12-28 1998-12-28 Saccharide conjugates and pharmaceutical compositions comprising them IL127773A0 (en)

Priority Applications (11)

Application Number	Priority Date	Filing Date	Title
IL12777398A IL127773A0 (en)	1998-12-28	1998-12-28	Saccharide conjugates and pharmaceutical compositions comprising them
AT99961263T ATE320439T1 (de)	1998-12-28	1999-12-28	Anti-(retro)virale konjugate von sacchariden und acetamidino- oder guanidinoverbindungen
PCT/IL1999/000704 WO2000039139A1 (en)	1998-12-28	1999-12-28	Anti-(retro)viral conjugates of saccharides and acetamidino or guanidino compounds
IL14399599A IL143995A0 (en)	1998-12-28	1999-12-28	Anti-(retro) viral conjugates of saccharides and acetamidino or guanidino compounds and pharmaceutical compositions comprising them
US09/869,437 US6642365B1 (en)	1998-12-28	1999-12-28	Anti-(retro)viral conjugates of saccharides and acetamidino or guanidino compounds
DE69930412T DE69930412T2 (de)	1998-12-28	1999-12-28	Anti-(retro)virale konjugate von sacchariden und acetamidino- oder guanidinoverbindungen
AU17956/00A AU1795600A (en)	1998-12-28	1999-12-28	Anti-(retro)viral conjugates of saccharides and acetamidino or guanidino compounds
HK02102642.6A HK1042904A1 (zh)	1998-12-28	1999-12-28	糖類和乙脒基或胍基化合物的抗(逆轉錄)病毒結合物
JP2000591050A JP2003525859A (ja)	1998-12-28	1999-12-28	糖類とアセトアミジノまたはグアニジノ化合物との抗−（レトロ）ウイルス結合体
EP99961263A EP1140958B1 (de)	1998-12-28	1999-12-28	Anti-(retro)virale konjugate von sacchariden und acetamidino- oder guanidinoverbindungen
IL143995A IL143995A (en)	1998-12-28	2001-06-26	Anti-(retro)viral conjugates of saccharides and acetamidino or guanidino compounds and pharmaceutical compositions comprising them

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IL12777398A IL127773A0 (en)	1998-12-28	1998-12-28	Saccharide conjugates and pharmaceutical compositions comprising them

Publications (1)

Publication Number	Publication Date
IL127773A0 true IL127773A0 (en)	1999-10-28

Family

ID=11072308

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL12777398A IL127773A0 (en)	1998-12-28	1998-12-28	Saccharide conjugates and pharmaceutical compositions comprising them
IL143995A IL143995A (en)	1998-12-28	2001-06-26	Anti-(retro)viral conjugates of saccharides and acetamidino or guanidino compounds and pharmaceutical compositions comprising them

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL143995A IL143995A (en)	1998-12-28	2001-06-26	Anti-(retro)viral conjugates of saccharides and acetamidino or guanidino compounds and pharmaceutical compositions comprising them

Country Status (9)

Country	Link
US (1)	US6642365B1 (de)
EP (1)	EP1140958B1 (de)
JP (1)	JP2003525859A (de)
AT (1)	ATE320439T1 (de)
AU (1)	AU1795600A (de)
DE (1)	DE69930412T2 (de)
HK (1)	HK1042904A1 (de)
IL (2)	IL127773A0 (de)
WO (1)	WO2000039139A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2829136B1 (fr) *	2001-08-29	2006-11-17	Aventis Pharma Sa	Derives lipidiques d'aminoglycosides
WO2003049772A2 (en) *	2001-12-11	2003-06-19	The Board Of Trustees Of The Leland Stanford Junior University	Guanidinium transport reagents and conjugates
US20050085432A1 (en) *	2001-12-26	2005-04-21	Aviva Lapidot	Methods of using conjugates of saccharides and acetamidino or guanidino compounds for treating bacterial infections
AU2002951247A0 (en) *	2002-09-06	2002-09-19	Alchemia Limited	Compounds that interact with kinases
WO2005060573A2 (en)	2003-12-15	2005-07-07	University Of Medicine And Dentistry Of New Jersey	Pna-neamine conjugates and methods for producing and using the same
CA2481491A1 (en)	2004-09-14	2006-03-14	Le Groupe Lysac Inc.	Amidinated or guanidinated polysaccharides, their use as absorbents and a process for producing same
CA2632968A1 (en)	2005-12-02	2007-06-07	Isis Pharmaceuticals, Inc.	Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents
FR2930942B1 (fr) *	2008-05-07	2011-03-04	Centre Nat Rech Scient	Nouvelles utilisations de derives de d-mannopyranose activateurs de l'angiogenese
WO2010030690A1 (en)	2008-09-10	2010-03-18	Isis Pharmaceuticals, Inc.	Antibacterial 4,6-substituted 6', 6" and 1 modified aminoglycoside analogs
WO2010030704A2 (en)	2008-09-10	2010-03-18	Achaogen, Inc.	Antibacterial aminoglycoside analogs
WO2010042851A1 (en)	2008-10-09	2010-04-15	Achaogen, Inc.	Antibacterial aminoglycoside analogs
WO2010042850A1 (en)	2008-10-09	2010-04-15	Achaogen, Inc.	Antibacterial aminoglycoside analogs
MX2012004036A (es)	2009-10-09	2012-06-27	Achaogen Inc	Analogos de aminoglicosidos antibacterianos.
US8774488B2 (en)	2010-03-11	2014-07-08	Cellscape Corporation	Method and device for identification of nucleated red blood cells from a maternal blood sample
AR083879A1 (es)	2010-11-17	2013-03-27	Achaogen Inc	Analogos de aminoglicosidos antibacterianos, metodos de preparacion y uso como agentes terapeuticos
US20200131231A1 (en)	2017-02-17	2020-04-30	Oxford University Innovation Limited	Cell penetrating peptides
GB201812980D0 (en)	2018-08-09	2018-09-26	Univ Oxford Innovation Ltd	Cell-penetrating peptides
GB201812972D0 (en)	2018-08-09	2018-09-26	Univ Oxford Innovation Ltd	Cell-penetrating peptides
EP3883943A4 (de) *	2018-11-22	2023-01-04	Technion Research & Development Foundation Limited	Modifizierte aminoglycosidverbindungen und ihre verwendungen zur deaktivierung von bakteriellen ribosomen
US12465646B2 (en)	2018-12-07	2025-11-11	Oxford University Innovation Limited	Linkers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE79034T1 (de) *	1987-10-14	1992-08-15	Ueno Seiyaku Oyo Kenkyujo Kk	Behandlung von viruskrankheiten.
WO1995000177A1 (en) *	1993-06-17	1995-01-05	Dextran Products Limited	Pharmaceutical preparation and a method for inhibiting the replication of various viruses
US5593835A (en) *	1995-05-12	1997-01-14	President And Fellows Of Harvard College	Methods and kits for RNA binding compounds

1998
- 1998-12-28 IL IL12777398A patent/IL127773A0/xx unknown
1999
- 1999-12-28 HK HK02102642.6A patent/HK1042904A1/zh unknown
- 1999-12-28 DE DE69930412T patent/DE69930412T2/de not_active Expired - Fee Related
- 1999-12-28 JP JP2000591050A patent/JP2003525859A/ja active Pending
- 1999-12-28 US US09/869,437 patent/US6642365B1/en not_active Expired - Fee Related
- 1999-12-28 EP EP99961263A patent/EP1140958B1/de not_active Expired - Lifetime
- 1999-12-28 WO PCT/IL1999/000704 patent/WO2000039139A1/en not_active Ceased
- 1999-12-28 AT AT99961263T patent/ATE320439T1/de not_active IP Right Cessation
- 1999-12-28 AU AU17956/00A patent/AU1795600A/en not_active Abandoned
2001
- 2001-06-26 IL IL143995A patent/IL143995A/en unknown

Also Published As

Publication number	Publication date
IL143995A (en)	2006-12-31
DE69930412D1 (de)	2006-05-11
WO2000039139A1 (en)	2000-07-06
DE69930412T2 (de)	2006-08-24
US6642365B1 (en)	2003-11-04
AU1795600A (en)	2000-07-31
ATE320439T1 (de)	2006-04-15
HK1042904A1 (zh)	2002-08-30
JP2003525859A (ja)	2003-09-02
EP1140958B1 (de)	2006-03-15
EP1140958A1 (de)	2001-10-10

Publication	Publication Date	Title
IL127773A0 (en)	1999-10-28	Saccharide conjugates and pharmaceutical compositions comprising them
IL118047A0 (en)	1996-08-04	Sulfated oligosaccharides pharmaceutical compositions containing them and their use
ATE409048T1 (de)	2008-10-15	Pharmazeutisch aktive oligosaccharid-conjugate
MX2009007415A (es)	2009-09-28	Sacaridos modificados.
DK0673258T3 (da)	2003-08-25	Polymerbundne camptothecinderivater
ES2118564T3 (es)	1998-09-16	Agente de limpieza para superficies duras.
SE9300954L (sv)	1994-09-24	Alkylglykosid, dess användning för rengöring samt komposition för detta ändamål
UA27108A1 (uk)	2000-02-28	Аhтрацикліhові глікозиди та їх фармацевтичhо прийhятhі кислотhо-адитивhі солі, спосіб їх одержаhhя, похідhі 1,6-дийод-3-оксапеhтаhу та спосіб їх одержаhhя
PT1020474E (pt)	2003-09-30	Derivados de oligossacaridos e processo para a sua obtencao
GR3015961T3 (en)	1995-07-31	Use of alkylglycosidsulfosuccinate in the preparation of cosmetic compositions and cleaning compositions.
HUT63171A (en)	1993-07-28	Process for producing anthracycline conjugates and pharmaceutical compositions comprising such compounds
MY110974A (en)	1999-07-31	Anthracycline conjugates, their preparation and their use as antitumor agents
WO2006012490A3 (en)	2007-03-01	Ketogenic saccharides
DE69624827D1 (de)	2002-12-19	5'-substitutierte-ribofuranosyl benzimidazolen als antivirale.
IL93258A0 (en)	1990-11-29	Anthracycline glycoside derivatives,their preparation and pharmaceutical compositions containing them
BG106123A (en)	2002-05-31	Diphosphate salt of a 4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin derivative and its pharmaceutical composition
GR3006831T3 (de)	1993-06-30
MX9704744A (es)	1997-10-31	Derivados de alquilpolisacarido y composiciones.
KR950028750A (ko)	1995-11-22	샴푸조성물
DE60238874D1 (de)	2011-02-17	Chromanol glucoside zur verbesserung der chemischen krebsbehandlung
TR199900982T2 (xx)	2000-07-21	�yonik olmayan y�zey aktif glikozitler i�in bir kristalizasyon �nleyici katk� maddesinin kullan�lmas�.
AU2323700A (en)	2000-08-25	Preventive and therapeutic agents for arteriosclerosis
WO1995016693A3 (en)	1995-07-20	4'-o-sulfonyl-anthracycline derivatives
EP1769799A3 (de)	2010-01-13	Pharmazeutische Zusammensetzung, welche steroidische Strukturen enthalten, und deren Verwendungen
CA2252717A1 (en)	1997-12-18	Colchicine-skeleton compounds, their use as medicaments and compositions containing them