IL129016A - Crystalline substance of cefditoren pivoxyl and the production of the same - Google Patents

Crystalline substance of cefditoren pivoxyl and the production of the same

Info

Publication number
IL129016A
IL129016A IL12901697A IL12901697A IL129016A IL 129016 A IL129016 A IL 129016A IL 12901697 A IL12901697 A IL 12901697A IL 12901697 A IL12901697 A IL 12901697A IL 129016 A IL129016 A IL 129016A
Authority
IL
Israel
Prior art keywords
production
same
crystalline substance
cefditoren pivoxyl
pivoxyl
Prior art date
Application number
IL12901697A
Other languages
English (en)
Other versions
IL129016A0 (en
Original Assignee
Meiji Seika Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha filed Critical Meiji Seika Kaisha
Publication of IL129016A0 publication Critical patent/IL129016A0/xx
Publication of IL129016A publication Critical patent/IL129016A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Liquid Crystal Substances (AREA)
IL12901697A 1996-09-20 1997-09-19 Crystalline substance of cefditoren pivoxyl and the production of the same IL129016A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24956196 1996-09-20
PCT/JP1997/003340 WO1998012200A1 (en) 1996-09-20 1997-09-19 A crystalline substance of cefditoren pivoxyl and the production of the same

Publications (2)

Publication Number Publication Date
IL129016A0 IL129016A0 (en) 2000-02-17
IL129016A true IL129016A (en) 2003-01-12

Family

ID=17194838

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12901697A IL129016A (en) 1996-09-20 1997-09-19 Crystalline substance of cefditoren pivoxyl and the production of the same

Country Status (25)

Country Link
US (2) US6294669B1 (de)
EP (1) EP0937083B1 (de)
JP (1) JP3403206B2 (de)
KR (1) KR100441907B1 (de)
CN (1) CN1116299C (de)
AR (1) AR008483A1 (de)
AT (1) ATE238310T1 (de)
AU (1) AU714735B2 (de)
BR (1) BR9712072A (de)
CA (1) CA2265686C (de)
CZ (1) CZ295199B6 (de)
DE (1) DE69721290T2 (de)
EA (1) EA001526B1 (de)
ES (1) ES2198593T3 (de)
HU (1) HU224196B1 (de)
ID (1) ID22064A (de)
IL (1) IL129016A (de)
NZ (1) NZ334883A (de)
PL (1) PL189548B1 (de)
PT (1) PT937083E (de)
RO (1) RO120196B1 (de)
SK (1) SK284973B6 (de)
TR (1) TR199900614T2 (de)
UA (1) UA55426C2 (de)
WO (1) WO1998012200A1 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998012200A1 (en) * 1996-09-20 1998-03-26 Meiji Seika Kaisha Ltd. A crystalline substance of cefditoren pivoxyl and the production of the same
HU230295B1 (hu) 1998-01-07 2015-12-28 Meiji Seika Pharma Co., Ltd. Kristálytanilag stabil, amorf, cephalosporin tartalmú készítmény és eljárás előállítására
HU230030B1 (hu) 1999-10-08 2015-05-28 Debiopharm International Sa Fab I inhibitorok
HU226640B1 (en) * 1999-10-18 2009-05-28 Egis Gyogyszergyar Nyilvanosan Process for producing amorphous atorvastatin calcium salt
JP2001131071A (ja) * 1999-10-29 2001-05-15 Meiji Seika Kaisha Ltd 非晶質および非晶質を含有する医薬組成物
EP1560584B1 (de) * 2001-04-06 2009-01-14 Affinium Pharmaceuticals, Inc. Fab-i-inhibitoren
DE60336149D1 (de) * 2002-08-16 2011-04-07 Immunogen Inc Vernetzer mit hoher reaktivität und löslichkeit und ihre verwendung bei der herstellung von konjugaten für die gezielte abgabe von kleinmolekularen arzneimitteln
AU2003235962A1 (en) * 2002-10-02 2004-04-23 Meiji Seika Kaisha, Ltd. Antibacterial medicinal composition of enhanced oral absorptivity
WO2004046154A1 (en) * 2002-11-15 2004-06-03 Orchid Chemicals & Pharmaceuticals Ltd Novel amorphous hydrate of a cephalosporin antibiotic
EP1575951B1 (de) * 2002-12-06 2014-06-25 Debiopharm International SA Heterozyclische verbindungen, verfahren zu deren herstellung und ihre verwendung als heilmittel
WO2004082586A2 (en) * 2003-03-17 2004-09-30 Affinium Pharmaceuticals, Inc. Phamaceutical compositions comprising inhibitors of fab i and further antibiotics
ES2329244T3 (es) * 2003-03-27 2009-11-24 Basilea Pharmaceutica Ag Cefalosporina en forma cristalina.
US8088387B2 (en) * 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
EP1660505A2 (de) * 2003-08-14 2006-05-31 Ranbaxy Laboratories Limited Verfahren zur selektiven herstellung des z-isomers von cefditoren und dessen pharmazeutisch unbedenklichen salzen und estern
CN1863535A (zh) 2003-10-08 2006-11-15 明治制果株式会社 含有头孢托仑匹伏酯的非晶性抗菌组合物
CN1902207A (zh) * 2003-11-07 2007-01-24 兰贝克赛实验室有限公司 高纯度3－(2－取代乙烯基)头孢菌素的制备方法
JP2005162696A (ja) * 2003-12-04 2005-06-23 Nichiko Pharmaceutical Co Ltd 溶出性に優れたセフジトレンピボキシル製剤
DK1828167T3 (da) * 2004-06-04 2014-10-20 Debiopharm Int Sa Acrylamidderivater som antibiotiske midler
WO2006024900A1 (en) * 2004-08-31 2006-03-09 Ranbaxy Laboratories Limited Highly pure cefditoren pivoxil
KR20080075027A (ko) * 2005-12-05 2008-08-13 아피늄 파마슈티컬스, 인크. Ｆａｂｉ 억제제 및 항박테리아제로서의헤테로시클릴아크릴아미드 화합물
US20080069879A1 (en) * 2006-05-02 2008-03-20 Ravishekhar Bhiwgade Stable solid dosage form containing amorphous cefditoren pivoxil and process for preparation thereof
JP5468899B2 (ja) 2006-07-20 2014-04-09 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉインヒビターとしてのアクリルアミド誘導体
EP2125802A4 (de) 2007-02-16 2014-08-20 Debiopharm Int Sa Salze, prodrugs und polymorphe von fab-i-inhibitoren
EP2520578A1 (de) 2011-05-06 2012-11-07 Lupin Limited Verfahren zur Reinigung von Cephalosporinen
CN103421025B (zh) * 2012-05-21 2016-05-11 上海医药工业研究院 制备7α-甲氧基头孢菌素C的方法
AU2013279021C1 (en) 2012-06-19 2017-03-16 Debiopharm International Sa Prodrug derivatives of (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
KR101561963B1 (ko) * 2013-05-23 2015-10-22 영진약품공업 주식회사 세프디토렌 피복실의 신규 결정 형태 및 이의 제조 방법
CN103665002B (zh) * 2013-12-18 2016-02-03 成都医路康医学技术服务有限公司 一种头孢妥仑匹酯的制备方法
EP3244879A1 (de) 2015-01-16 2017-11-22 Ögün, Yusuf Toktamis Cefditoren-pivoxil-zusammensetzungen mit verbesserter stabilität und herstellungsverfahren dafür
RS61312B1 (sr) 2016-02-26 2021-02-26 Debiopharm Int Sa Lek za lečenje infekcija dijabetskog stopala
TN2021000159A1 (en) 2019-02-14 2023-04-04 Debiopharm Int Sa Afabicin formulation, method for making the same and uses thereof
SG11202113174SA (en) 2019-06-14 2021-12-30 Debiopharm Int Sa Medicament and use thereof for treating bacterial infections involving biofilm

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58487B1 (en) 1984-09-07 1993-09-22 Kaisha Maiji Seika New cephalosporin compounds and the production thereof
WO1995009171A1 (en) * 1993-09-29 1995-04-06 Meiji Seika Kaisha, Ltd. Novel cephalosporin derivative
DE69427312T2 (de) * 1993-11-17 2001-08-23 Biochemie Ges.M.B.H., Kundl Trennung von Cephalosporinisomeren
WO1998012200A1 (en) * 1996-09-20 1998-03-26 Meiji Seika Kaisha Ltd. A crystalline substance of cefditoren pivoxyl and the production of the same

Also Published As

Publication number Publication date
CN1234036A (zh) 1999-11-03
CA2265686A1 (en) 1998-03-26
BR9712072A (pt) 1999-08-24
EP0937083B1 (de) 2003-04-23
CA2265686C (en) 2006-10-31
JP2001500521A (ja) 2001-01-16
AU714735B2 (en) 2000-01-13
KR100441907B1 (ko) 2004-07-27
AR008483A1 (es) 2000-01-19
US20020002279A1 (en) 2002-01-03
DE69721290D1 (de) 2003-05-28
AU4222297A (en) 1998-04-14
HUP9903454A3 (en) 2001-04-28
SK284973B6 (sk) 2006-03-02
SK35499A3 (en) 2000-03-13
EA199900311A1 (ru) 1999-10-28
HUP9903454A2 (hu) 2000-03-28
RO120196B1 (ro) 2005-10-28
ATE238310T1 (de) 2003-05-15
CZ97599A3 (cs) 1999-08-11
US6441162B2 (en) 2002-08-27
IL129016A0 (en) 2000-02-17
NZ334883A (en) 2000-09-29
JP3403206B2 (ja) 2003-05-06
ID22064A (id) 1999-08-26
CZ295199B6 (cs) 2005-06-15
UA55426C2 (uk) 2003-04-15
EP0937083A1 (de) 1999-08-25
HK1022912A1 (en) 2000-08-25
TR199900614T2 (xx) 1999-06-21
CN1116299C (zh) 2003-07-30
HU224196B1 (hu) 2005-06-28
WO1998012200A1 (en) 1998-03-26
PL332314A1 (en) 1999-08-30
KR20000048496A (ko) 2000-07-25
DE69721290T2 (de) 2004-01-22
PT937083E (pt) 2003-08-29
PL189548B1 (pl) 2005-08-31
US6294669B1 (en) 2001-09-25
ES2198593T3 (es) 2004-02-01
EA001526B1 (ru) 2001-04-23

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