IL134468A0 - 9-hydrazone and 9-azine erythromycin derivatives and a process of making the same - Google Patents

9-hydrazone and 9-azine erythromycin derivatives and a process of making the same

Info

Publication number
IL134468A0
IL134468A0 IL13446898A IL13446898A IL134468A0 IL 134468 A0 IL134468 A0 IL 134468A0 IL 13446898 A IL13446898 A IL 13446898A IL 13446898 A IL13446898 A IL 13446898A IL 134468 A0 IL134468 A0 IL 134468A0
Authority
IL
Israel
Prior art keywords
hydrazone
making
same
erythromycin derivatives
azine
Prior art date
Application number
IL13446898A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of IL134468A0 publication Critical patent/IL134468A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Solid Thermionic Cathode (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL13446898A 1997-09-10 1998-09-01 9-hydrazone and 9-azine erythromycin derivatives and a process of making the same IL134468A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/927,057 US5929219A (en) 1997-09-10 1997-09-10 9-hydrazone and 9-azine erythromycin derivatives and a process of making the same
PCT/US1998/018115 WO1999012946A1 (fr) 1997-09-10 1998-09-01 Derives d'erythromycine 9-hydrazone et 9-azine et procede de preparation de ces derniers

Publications (1)

Publication Number Publication Date
IL134468A0 true IL134468A0 (en) 2001-04-30

Family

ID=25454102

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13446898A IL134468A0 (en) 1997-09-10 1998-09-01 9-hydrazone and 9-azine erythromycin derivatives and a process of making the same
IL134468A IL134468A (en) 1997-09-10 2000-02-09 9 - hydrazone and 9 - azine

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL134468A IL134468A (en) 1997-09-10 2000-02-09 9 - hydrazone and 9 - azine

Country Status (13)

Country Link
US (2) US5929219A (fr)
EP (1) EP1015466B1 (fr)
JP (1) JP2001515914A (fr)
KR (1) KR100553468B1 (fr)
AT (1) ATE239751T1 (fr)
AU (1) AU9213698A (fr)
CA (1) CA2301639C (fr)
DE (1) DE69814422T2 (fr)
DK (1) DK1015466T3 (fr)
ES (1) ES2198745T3 (fr)
IL (2) IL134468A0 (fr)
PT (1) PT1015466E (fr)
WO (1) WO1999012946A1 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL124084A0 (en) * 1998-04-14 1999-04-11 Chemagis Ltd Erythromycin a derivatives and methods for the preparation thereof
IL125372A0 (en) * 1998-07-15 1999-03-12 Chemagis Ltd Erythromycin derivatives and methods for the preparation thereof
KR100317907B1 (ko) * 1998-11-24 2001-12-24 김 완 주 신규한 중간체, 이를 이용한 마크로라이드계 항생제의제조방법
US6437106B1 (en) 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives
US6565882B2 (en) 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
AU2578701A (en) * 2000-02-29 2001-09-12 Teva Pharma Processes for preparing clarithromycin and clarithromycin intermediate, essentially oxime-free clarithromycin, and pharmaceutical composition comprising the same
US6605707B1 (en) 2000-03-23 2003-08-12 Abbott Laboratories Process for the preparation of 6-O-propargyl erythromycin derivatives
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6541014B2 (en) 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US7435805B2 (en) 2003-05-30 2008-10-14 Glaxpsmithkline Istrazivacki O-alkyl macrolide and azalide derivatives and regioselective process for their preparation
CA2533292C (fr) 2003-07-21 2013-12-31 Advancis Pharmaceutical Corporation Produit antibiotique, utilisation et formulation correspondantes
EP1648415A4 (fr) 2003-07-21 2011-11-16 Middlebrook Pharmaceuticals Inc Produit antibiotique, son utilisation et sa formulation
EP1648418A4 (fr) 2003-07-21 2011-11-16 Middlebrook Pharmaceuticals Inc Produit antibiotique, utilisation et formulation associees
WO2005016311A1 (fr) 2003-08-11 2005-02-24 Advancis Pharmaceutical Corporation Pastille robuste
CA2535398C (fr) 2003-08-12 2013-11-12 Advancis Pharmaceuticals Corporation Antibiotique, utilisation et formulation associees
EP1658034A4 (fr) 2003-08-29 2011-06-22 Middlebrook Pharmaceuticals Inc Produit antibiotique, son utilisation et sa formulation
WO2005027877A1 (fr) 2003-09-15 2005-03-31 Advancis Pharmaceutical Corporation Antibiotique, son utilisation et sa formulation
US8715727B2 (en) 2004-07-02 2014-05-06 Shionogi Inc. Tablet for pulsed delivery
FI117133B (fi) 2004-10-19 2006-06-30 Auramo Oy Menetelmä ja pihtilaite kuormien käsittelemiseksi
ES2261090B1 (es) * 2005-04-25 2007-06-16 Ercros Industrial, S.A. Procedimiento de obtencion de derivados de eritromicina a y compuestos obtenidos.
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
EP2077271A4 (fr) * 2006-05-01 2010-09-15 Taisho Pharmaceutical Co Ltd Derive macrolide
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
US20090054634A1 (en) * 2007-08-09 2009-02-26 Vinod Kumar Kansal Process for the preparation of clarithromycin
CN102382157B (zh) * 2010-09-03 2015-04-08 上海医药工业研究院 一种红霉素a衍生物及其制备方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759252A (fr) 1969-11-21 1971-05-21 Lilly Co Eli Erytromycyl b amine
GB1344629A (en) 1970-09-30 1974-01-23 Lilly Industries Ltd Erythromycin azine derivatives
US3869444A (en) 1972-10-10 1975-03-04 Abbott Lab Esters of erythromycin oxime
FR2473525A1 (fr) 1980-01-11 1981-07-17 Roussel Uclaf Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
US4331803A (en) * 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
US4336368A (en) 1981-04-20 1982-06-22 Pfizer Inc. 4 Deoxy-4-methylene oleandomycin and derivatives thereof
JPS5896095A (ja) 1981-11-30 1983-06-07 Taisho Pharmaceut Co Ltd １１−ｏ−アルキルエリスロマイシンａ誘導体
JPS5896097A (ja) 1981-12-01 1983-06-07 Taisho Pharmaceut Co Ltd エリスロマイシンｂ誘導体
JPS5896098A (ja) 1981-12-03 1983-06-07 Taisho Pharmaceut Co Ltd エリスロマイシンａ誘導体
US4526889A (en) 1982-11-15 1985-07-02 Pfizer Inc. Epimeric azahomoerythromycin A derivative, intermediates and method of use
JPS60214796A (ja) * 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシン類の製法
JPS61103890A (ja) * 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシンａ誘導体
PT82162B (en) 1985-03-12 1987-08-06 Beecham Group Plc Chemical compounds
GB8506380D0 (en) 1985-03-12 1985-04-11 Beecham Group Plc Chemical compounds
US4670549A (en) * 1985-03-18 1987-06-02 Taisho Pharmaceutical Co., Ltd. Method for selective methylation of erythromycin a derivatives
JPS61229895A (ja) * 1985-04-03 1986-10-14 Nippon Zeon Co Ltd 保護化デス−ｎ−メチルエリスロマイシン誘導体
US4640910A (en) 1985-11-12 1987-02-03 Abbott Laboratories Erythromycin A silylated compounds and method of use
JPS63107994A (ja) 1986-05-02 1988-05-12 Taisho Pharmaceut Co Ltd エリスロマイシン誘導体
US4740502A (en) 1986-06-20 1988-04-26 Abbott Laboratories Semisynthetic erythromycin antibiotics
DE3782994T2 (de) * 1986-09-18 1993-04-08 Taisho Pharma Co Ltd Erythromycin-a-derivate und verfahren zu ihrer herstellung.
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
GB8721165D0 (en) 1987-09-09 1987-10-14 Beecham Group Plc Chemical compounds
JP2751385B2 (ja) * 1988-05-19 1998-05-18 大正製薬株式会社 エリスロマイシンａオキシム及びその塩の製造方法
US5302705A (en) 1989-10-07 1994-04-12 Taisho Pharmaceutical Co., Ltd. 6-O-methylerythromycin a oxime derivatives

Also Published As

Publication number Publication date
WO1999012946A1 (fr) 1999-03-18
AU9213698A (en) 1999-03-29
ES2198745T3 (es) 2004-02-01
EP1015466A1 (fr) 2000-07-05
CA2301639A1 (fr) 1999-03-18
DE69814422T2 (de) 2004-05-06
CA2301639C (fr) 2007-06-26
IL134468A (en) 2009-09-01
KR20010023778A (ko) 2001-03-26
EP1015466B1 (fr) 2003-05-07
PT1015466E (pt) 2003-09-30
JP2001515914A (ja) 2001-09-25
DK1015466T3 (da) 2003-09-01
ATE239751T1 (de) 2003-05-15
KR100553468B1 (ko) 2006-02-22
USRE39531E1 (en) 2007-03-27
DE69814422D1 (de) 2003-06-12
US5929219A (en) 1999-07-27

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