IL136529A - Benzodioxan, benzofuran or benzopyran derivatives having fundic relaxation properties, their preparation and pharmaceutical compositions containing them - Google Patents

Benzodioxan, benzofuran or benzopyran derivatives having fundic relaxation properties, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL136529A
IL136529A IL13652998A IL13652998A IL136529A IL 136529 A IL136529 A IL 136529A IL 13652998 A IL13652998 A IL 13652998A IL 13652998 A IL13652998 A IL 13652998A IL 136529 A IL136529 A IL 136529A
Authority
IL
Israel
Prior art keywords
benzodioxan
benzofuran
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL13652998A
Other languages
English (en)
Other versions
IL136529A0 (en
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IL136529A0 publication Critical patent/IL136529A0/xx
Publication of IL136529A publication Critical patent/IL136529A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL13652998A 1997-12-05 1998-11-27 Benzodioxan, benzofuran or benzopyran derivatives having fundic relaxation properties, their preparation and pharmaceutical compositions containing them IL136529A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97203808 1997-12-05
PCT/EP1998/007771 WO1999029687A1 (fr) 1997-12-05 1998-11-27 Derives (de benzodioxane, de benzofurane ou de benzopyrane) possedant des proprietes de relachement fundique

Publications (2)

Publication Number Publication Date
IL136529A0 IL136529A0 (en) 2001-06-14
IL136529A true IL136529A (en) 2003-03-12

Family

ID=8229014

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13652998A IL136529A (en) 1997-12-05 1998-11-27 Benzodioxan, benzofuran or benzopyran derivatives having fundic relaxation properties, their preparation and pharmaceutical compositions containing them

Country Status (31)

Country Link
US (4) US6133277A (fr)
EP (1) EP1036073B8 (fr)
JP (1) JP2001525407A (fr)
KR (1) KR100591605B1 (fr)
CN (1) CN1155597C (fr)
AR (1) AR017195A1 (fr)
AT (1) ATE334125T1 (fr)
AU (1) AU748669B2 (fr)
BG (1) BG64624B1 (fr)
BR (1) BR9814256A (fr)
CA (1) CA2311669C (fr)
CO (1) CO5011114A1 (fr)
CZ (1) CZ297895B6 (fr)
DE (1) DE69835372T2 (fr)
EA (1) EA003365B1 (fr)
EE (1) EE04438B1 (fr)
ES (1) ES2270541T3 (fr)
HR (1) HRP20000340B1 (fr)
HU (1) HU224813B1 (fr)
ID (1) ID24616A (fr)
IL (1) IL136529A (fr)
MY (1) MY124586A (fr)
NO (1) NO320727B1 (fr)
NZ (1) NZ503603A (fr)
PL (1) PL191144B1 (fr)
SK (1) SK286268B6 (fr)
TR (1) TR200001542T2 (fr)
TW (1) TW577886B (fr)
UA (1) UA70308C2 (fr)
WO (1) WO1999029687A1 (fr)
ZA (1) ZA9811081B (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133277A (en) 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
EE04780B1 (et) * 1999-06-02 2007-02-15 Janssen Pharmaceutica N.V. Aminoalküül-asendatud bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod
SK286159B6 (sk) * 1999-06-02 2008-04-07 Janssen Pharmaceutica N. V. Benzodioxánový, benzofuránový alebo benzopyránovýderivát, spôsob jeho prípravy, tento derivát na použitie ako liečivo, farmaceutická kompozícia obsahujúca tento derivát a spôsob jej prípravy
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) * 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
US6688079B2 (en) 2001-04-18 2004-02-10 Kraft Foods Holdings, Inc. Method for manufacturing flexible packages having slide closures
JPWO2003040382A1 (ja) * 2001-11-09 2005-03-03 株式会社カネカ 光学活性クロマン誘導体の製造法および中間体
ES2199086B1 (es) 2002-07-31 2005-06-01 Cepa Schwarz Pharma Sl Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas.
US7071821B2 (en) * 2003-05-14 2006-07-04 Bellsouth Intellectual Property Corporation Method and system for alerting a person to a situation
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
WO2005033093A1 (fr) 2003-09-19 2005-04-14 Galileo Pharmaceuticals, Inc. Derives du 7,8-bicycloalkyl-chroman
BRPI0416206A (pt) 2003-11-20 2006-12-26 Janssen Pharmaceutica Nv 2-quinolinonas e 2-quinoxalinonas substituìdas por 6-alquenila e 6-fenilalquila como inibidores de polimerase de poli(adp-ribose)
CA2546002C (fr) 2003-11-20 2012-09-18 Janssen Pharmaceutica N.V. 2-quinolinones et 2 quinoxalinones a substitution 7-phenylalkyl tenant lieu d'inhibiteurs de poly(adp-ribose) polymerase inhibitors
ES2238015B1 (es) * 2004-01-30 2006-11-01 Cepa Schwarz Pharma, S.L. Derivados de cicloalcanodionas con actividad neuroprotectora.
EA011552B1 (ru) 2004-06-30 2009-04-28 Янссен Фармацевтика Н.В. Производные хиназолиндиона в качестве ингибиторов parp
SG154433A1 (en) 2004-06-30 2009-08-28 Janssen Pharmaceutica Nv Phthalazine derivatives as parp inhibitors
ATE540936T1 (de) 2004-06-30 2012-01-15 Janssen Pharmaceutica Nv Substituierte 2-alkyl-chinazolinonderivate als parp-hemmer
RU2391350C2 (ru) * 2004-07-02 2010-06-10 Базелль Полиолефине Гмбх Способ рацемоселективного синтеза анса-металлоценов
DE102004032277A1 (de) * 2004-07-02 2006-01-19 Basell Polyolefine Gmbh Verfahren zur racemoselektiven Synthese von ansa-Metallocenen
JP2008530229A (ja) 2005-02-17 2008-08-07 ワイス シクロアルキル縮合インドール、ベンゾチオフェン、ベンゾフランおよびインデン誘導体
WO2006116165A1 (fr) * 2005-04-22 2006-11-02 Wyeth Derives de chromane et de chromene, et leurs utilisations
WO2008015538A2 (fr) * 2006-07-31 2008-02-07 Schwarz Pharma S.L. Procédés pour prévenir et/ou traiter la douleur et/ou la migraine
US20080033050A1 (en) 2006-08-04 2008-02-07 Richards Patricia Allison Tewe Method of treating thermoregulatory disfunction with paroxetine
US8503431B2 (en) * 2006-08-25 2013-08-06 Wireless Wonders Ltd. Mobile phone related indirect communication system and method
US8299256B2 (en) 2007-03-08 2012-10-30 Janssen Pharmaceutica Nv Quinolinone derivatives as PARP and TANK inhibitors
JP5017703B2 (ja) * 2007-05-16 2012-09-05 住友ゴム工業株式会社 ビードエイペックスおよびタイヤ
US8404713B2 (en) 2007-10-26 2013-03-26 Janssen Pharmaceutica Nv Quinolinone derivatives as PARP inhibitors
ES2367760T3 (es) 2008-03-27 2011-11-08 Janssen Pharmaceutica, N.V. Derivados de quinazolinona como inhibidores de la polimerización de la tubulina.
CN101981013B (zh) 2008-03-27 2013-05-29 詹森药业有限公司 作为parp和微管蛋白聚合抑制剂的四氢菲啶酮和四氢环戊二烯并喹啉酮
PL2817299T3 (pl) 2012-02-24 2019-12-31 Lupin Limited Podstawione związki chromanowe jako modulatory receptorów wapniowych
DE102012206062B4 (de) 2012-04-13 2019-09-12 Adidas Ag Schuhoberteil
WO2014102592A2 (fr) 2012-12-27 2014-07-03 Purdue Pharma L.P. Composés de pipéridine de type quinoxaline substituée par oxime et leurs utilisations
DE102013207163B4 (de) 2013-04-19 2022-09-22 Adidas Ag Schuhoberteil
DE102014220087B4 (de) 2014-10-02 2016-05-12 Adidas Ag Flachgestricktes Schuhoberteil für Sportschuhe
EP3397643A1 (fr) 2015-12-30 2018-11-07 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Promédicaments pt(v)
CN119462701A (zh) * 2024-10-11 2025-02-18 合肥工业大学 一种四吡啶草酸铜金属配合物的制备及用途

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US3910930A (en) * 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US3929801A (en) * 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
GB1599296A (en) * 1977-07-06 1981-09-30 Brewster D L Ice making machine
GR71865B (fr) * 1978-03-20 1983-07-07 Ciba Geigy
DE2852945A1 (de) * 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
US4239348A (en) * 1979-11-30 1980-12-16 Hughes Aircraft Company High resolution AC silicon MOS light-valve substrate
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4140540A1 (de) * 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE4319038A1 (de) * 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
ES2212797T3 (es) * 1993-08-19 2004-08-01 Janssen Pharmaceutica N.V. Derivados de dihidrobenzopirano vasoconstrictores.
US5541199A (en) * 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
FR2744451B1 (fr) * 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US5696653A (en) * 1996-12-13 1997-12-09 Phase Metrics Tooling for holding a head gimbal assembly
US6133277A (en) 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties

Also Published As

Publication number Publication date
HRP20000340A2 (en) 2001-04-30
ATE334125T1 (de) 2006-08-15
US20030149093A1 (en) 2003-08-07
EE04438B1 (et) 2005-02-15
IL136529A0 (en) 2001-06-14
AR017195A1 (es) 2001-08-22
WO1999029687A8 (fr) 2000-04-13
KR20010031010A (ko) 2001-04-16
ID24616A (id) 2000-07-27
EE200000328A (et) 2001-08-15
UA70308C2 (uk) 2004-10-15
AU2412799A (en) 1999-06-28
NO20002074L (no) 2000-06-02
NZ503603A (en) 2001-10-26
ES2270541T3 (es) 2007-04-01
US6747045B2 (en) 2004-06-08
EP1036073B8 (fr) 2006-11-15
NO320727B1 (no) 2006-01-23
HUP0004492A3 (en) 2002-04-29
CO5011114A1 (es) 2001-02-28
BG64624B1 (bg) 2005-09-30
ZA9811081B (en) 2000-06-22
EP1036073A1 (fr) 2000-09-20
EP1036073B1 (fr) 2006-07-26
DE69835372D1 (de) 2006-09-07
CZ297895B6 (cs) 2007-04-25
EA200000616A1 (ru) 2000-12-25
CA2311669C (fr) 2010-04-27
US6133277A (en) 2000-10-17
CN1155597C (zh) 2004-06-30
JP2001525407A (ja) 2001-12-11
HU224813B1 (en) 2006-02-28
CN1280577A (zh) 2001-01-17
BR9814256A (pt) 2000-10-03
NO20002074D0 (no) 2000-04-19
MY124586A (en) 2006-06-30
KR100591605B1 (ko) 2006-06-20
US6852714B2 (en) 2005-02-08
SK8032000A3 (en) 2001-02-12
SK286268B6 (sk) 2008-06-06
WO1999029687A1 (fr) 1999-06-17
CZ20002018A3 (cs) 2000-10-11
AU748669B2 (en) 2002-06-06
HRP20000340B1 (hr) 2008-12-31
DE69835372T2 (de) 2007-08-09
HUP0004492A2 (hu) 2002-03-28
US20030083365A1 (en) 2003-05-01
US6495547B1 (en) 2002-12-17
TR200001542T2 (tr) 2001-01-22
PL341007A1 (en) 2001-03-12
EA003365B1 (ru) 2003-04-24
BG104372A (en) 2000-12-29
PL191144B1 (pl) 2006-03-31
HK1028400A1 (en) 2001-02-16
TW577886B (en) 2004-03-01
CA2311669A1 (fr) 1999-06-17

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Legal Events

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KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees