IL138672A0 - Liposomal bupivacaine compositions and methods of preparation - Google Patents
Liposomal bupivacaine compositions and methods of preparationInfo
- Publication number
- IL138672A0 IL138672A0 IL13867299A IL13867299A IL138672A0 IL 138672 A0 IL138672 A0 IL 138672A0 IL 13867299 A IL13867299 A IL 13867299A IL 13867299 A IL13867299 A IL 13867299A IL 138672 A0 IL138672 A0 IL 138672A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- methods
- liposomal bupivacaine
- bupivacaine compositions
- compositions
- Prior art date
Links
- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Anesthesiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8019598P | 1998-03-31 | 1998-03-31 | |
| PCT/US1999/006958 WO1999049849A1 (fr) | 1998-03-31 | 1999-03-30 | Compositions de liposomes de bupivacaine et leurs methodes de preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL138672A0 true IL138672A0 (en) | 2001-10-31 |
Family
ID=22155864
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13867299A IL138672A0 (en) | 1998-03-31 | 1999-03-30 | Liposomal bupivacaine compositions and methods of preparation |
| IL138672A IL138672A (en) | 1998-03-31 | 2000-09-24 | Liposome liposome preparations containing anesthetic, method of preparation and uses |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL138672A IL138672A (en) | 1998-03-31 | 2000-09-24 | Liposome liposome preparations containing anesthetic, method of preparation and uses |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6926905B2 (fr) |
| EP (1) | EP1071401A4 (fr) |
| AU (1) | AU757686B2 (fr) |
| CA (1) | CA2326348C (fr) |
| IL (2) | IL138672A0 (fr) |
| WO (1) | WO1999049849A1 (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ515644A (en) * | 1999-06-04 | 2004-12-24 | Skyepharma Inc | Oil-core compositions for the sustained release of hydrophobic drugs |
| KR100343125B1 (ko) * | 1999-09-14 | 2002-07-05 | 임정옥 | 도포용 리포좀형 혼합국소마취제 및 그 제조방법 |
| KR20010090030A (ko) * | 2001-08-09 | 2001-10-18 | 임정옥 | 경피마취효과가 월등한 혼합형 마취제의 제형방법 |
| US20030157162A1 (en) * | 2002-01-22 | 2003-08-21 | Krugner-Higby Lisa A. | Liposome-encapsulated opioid analgesics |
| AU2004233873B2 (en) | 2003-04-25 | 2010-11-18 | The Penn State Research Foundation | Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds |
| JP2007522085A (ja) * | 2003-06-27 | 2007-08-09 | スミスクライン・ビーチャム・コーポレイション | 安定化されたトポテカンリポソーム組成物および方法 |
| US8753673B2 (en) * | 2006-05-23 | 2014-06-17 | Taiwan Liposome Co. Ltd. | Liposome composition for delivery of a therapeutic agent to eyes |
| US9713591B2 (en) * | 2008-10-07 | 2017-07-25 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | Composition of matter comprising liposomes embedded in a polymeric matrix and methods of using same |
| EP2576813A1 (fr) | 2010-05-28 | 2013-04-10 | Diagon Kft. | Procédé pour la préparation biphasique de liposomes et son utilisation dans la fabrication de réactifs de diagnostic |
| EP3043769B1 (fr) | 2013-09-11 | 2023-06-07 | AIM Targeted Therapies, Inc. | Compositions thérapeutiques antimicrobiennes hypertoniques |
| CA2939916A1 (fr) | 2014-02-18 | 2015-08-27 | Glenn Abrahmsohn | Compositions et methodes destinees a attenuer la douleur sans engourdir |
| CN111182889A (zh) | 2017-08-28 | 2020-05-19 | 美商Tlc生物医药公司 | 缓释麻醉剂组成物及其制备方法 |
| CN115350154A (zh) | 2018-03-30 | 2022-11-18 | 美商Tlc生物医药公司 | 用以制备麻醉剂组成物的脂质饼块及其用途 |
| JP2022523208A (ja) * | 2019-02-26 | 2022-04-21 | ティーエルシー バイオファーマシューティカルズ、インク. | 疼痛の治療に使用するための医薬組成物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4880635B1 (en) * | 1984-08-08 | 1996-07-02 | Liposome Company | Dehydrated liposomes |
| EP0225130B1 (fr) | 1985-11-22 | 1991-10-30 | Takeda Chemical Industries, Ltd. | Composition de liposomes |
| US5244678A (en) * | 1986-01-14 | 1993-09-14 | Ire-Celltarg S.A. | Pharmaceutical composition containing a local anesthetic and/or centrally acting analgesic encapsulated in liposomes |
| CH672733A5 (fr) | 1987-05-22 | 1989-12-29 | Bracco Ind Chimica Spa | |
| US5244878A (en) * | 1987-12-30 | 1993-09-14 | Institut Francais Du Petrole | Process for delaying the formation and/or reducing the agglomeration tendency of hydrates |
| GB9609779D0 (en) * | 1996-05-10 | 1996-07-17 | Univ Bruxelles | Freeze dried liposome encapsulated amphiphilic drug compositions and a process for the preparation thereof |
-
1999
- 1999-03-30 CA CA002326348A patent/CA2326348C/fr not_active Expired - Fee Related
- 1999-03-30 AU AU33720/99A patent/AU757686B2/en not_active Ceased
- 1999-03-30 EP EP99915127A patent/EP1071401A4/fr not_active Withdrawn
- 1999-03-30 IL IL13867299A patent/IL138672A0/xx active IP Right Grant
- 1999-03-30 WO PCT/US1999/006958 patent/WO1999049849A1/fr not_active Ceased
-
2000
- 2000-09-24 IL IL138672A patent/IL138672A/en not_active IP Right Cessation
-
2003
- 2003-07-16 US US10/620,006 patent/US6926905B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20040018230A1 (en) | 2004-01-29 |
| EP1071401A4 (fr) | 2002-05-15 |
| EP1071401A1 (fr) | 2001-01-31 |
| CA2326348C (fr) | 2009-10-06 |
| US6926905B2 (en) | 2005-08-09 |
| AU3372099A (en) | 1999-10-18 |
| WO1999049849A1 (fr) | 1999-10-07 |
| CA2326348A1 (fr) | 1999-10-07 |
| AU757686B2 (en) | 2003-03-06 |
| IL138672A (en) | 2006-07-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed |