IL142068A0 - Compositions containing a derivative of hyaluronic acid and methods for the preparation thereof - Google Patents

Compositions containing a derivative of hyaluronic acid and methods for the preparation thereof

Info

Publication number
IL142068A0
IL142068A0 IL14206899A IL14206899A IL142068A0 IL 142068 A0 IL142068 A0 IL 142068A0 IL 14206899 A IL14206899 A IL 14206899A IL 14206899 A IL14206899 A IL 14206899A IL 142068 A0 IL142068 A0 IL 142068A0
Authority
IL
Israel
Prior art keywords
hyaluronic acid
methods
derivative
preparation
compositions containing
Prior art date
Application number
IL14206899A
Other languages
English (en)
Original Assignee
Orthogene L L C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orthogene L L C filed Critical Orthogene L L C
Publication of IL142068A0 publication Critical patent/IL142068A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/70Polysaccharides
    • C12N2533/80Hyaluronan

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
IL14206899A 1998-09-18 1999-09-17 Compositions containing a derivative of hyaluronic acid and methods for the preparation thereof IL142068A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/156,829 US6630457B1 (en) 1998-09-18 1998-09-18 Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
PCT/EP1999/006913 WO2000016818A1 (en) 1998-09-18 1999-09-17 Functionalized derivatives of hyaluronic acid and formation of hydrogels in situ using same

Publications (1)

Publication Number Publication Date
IL142068A0 true IL142068A0 (en) 2002-03-10

Family

ID=22561268

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14206899A IL142068A0 (en) 1998-09-18 1999-09-17 Compositions containing a derivative of hyaluronic acid and methods for the preparation thereof
IL142068A IL142068A (en) 1998-09-18 2001-03-18 Compositions containing a derivative of hyaluronic acid and methods for the preparation thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL142068A IL142068A (en) 1998-09-18 2001-03-18 Compositions containing a derivative of hyaluronic acid and methods for the preparation thereof

Country Status (8)

Country Link
US (3) US6630457B1 (de)
EP (2) EP1115433B1 (de)
AT (1) ATE284229T1 (de)
AU (1) AU6192299A (de)
CA (1) CA2344215A1 (de)
DE (1) DE69922522T2 (de)
IL (2) IL142068A0 (de)
WO (1) WO2000016818A1 (de)

Families Citing this family (196)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1303738B1 (it) * 1998-11-11 2001-02-23 Aquisitio S P A Processo di reticolazione di polisaccaridi carbossilati.
JP2001037472A (ja) * 1999-07-28 2001-02-13 Bio Quest:Kk 三次元細胞培養基材及びそれを用いた細胞培養方法
ATE271886T1 (de) 1999-10-15 2004-08-15 Inst Genetics Llc Hyaluronsäure enthaltende zusammensetzungen zur abgabe osteogener proteine
MXPA04006875A (es) * 2002-01-18 2004-12-06 Control Delivery Sys Inc Sistema de gel polimerico para suministro controlado de cofarmacos.
ITPD20020064A1 (it) * 2002-03-12 2003-09-12 Fidia Advanced Biopolymers Srl Derivati esterei dell'acido ialuronico per la preparazione di idrogelda utilizzare in campo biomedico, sanitario e chirurgico e come sistem
TW200638946A (en) 2002-05-17 2006-11-16 Wyeth Corp Injectable solid hyaluronic acid carriers for delivery of osteogenic proteins
CA2489712C (en) 2002-06-21 2016-07-12 University Of Utah Research Foundation Crosslinked compounds and methods of making and using thereof
US7034127B2 (en) * 2002-07-02 2006-04-25 Genzyme Corporation Hydrophilic biopolymer-drug conjugates, their preparation and use
WO2004060404A1 (ja) * 2002-12-27 2004-07-22 Chugai Seiyaku Kabushiki Kaisha 薬物担体
US7465766B2 (en) 2004-01-08 2008-12-16 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US8137688B2 (en) 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US6982298B2 (en) 2003-01-10 2006-01-03 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US8138265B2 (en) 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
US8383158B2 (en) 2003-04-15 2013-02-26 Abbott Cardiovascular Systems Inc. Methods and compositions to treat myocardial conditions
DE10318801A1 (de) * 2003-04-17 2004-11-04 Aesculap Ag & Co. Kg Flächiges Implantat und seine Verwendung in der Chirurgie
US8073538B2 (en) 2003-11-13 2011-12-06 Cardio Polymers, Inc. Treatment of cardiac arrhythmia by modification of neuronal signaling through fat pads of the heart
AU2004297231B2 (en) 2003-12-04 2012-02-02 University Of Utah Research Foundation Modified macromolecules and associated methods of synthesis and use
JPWO2005054302A1 (ja) * 2003-12-05 2007-12-06 中外製薬株式会社 薬物担体及びその製造方法
US8124120B2 (en) * 2003-12-22 2012-02-28 Anika Therapeutics, Inc. Crosslinked hyaluronic acid compositions for tissue augmentation
JP4566189B2 (ja) * 2004-03-15 2010-10-20 テルモ株式会社 癒着防止材
US8293890B2 (en) 2004-04-30 2012-10-23 Advanced Cardiovascular Systems, Inc. Hyaluronic acid based copolymers
WO2005112888A2 (en) * 2004-05-20 2005-12-01 Mentor Corporation Methods for making injectable polymer hydrogels
EP1763552A1 (de) * 2004-07-08 2007-03-21 Symatese Lyophilisierter klebstoff auf kollagenbasis und dessen verwendung zur herstellung einer haftprothese
FR2873379B1 (fr) * 2004-07-23 2008-05-16 Jerome Asius Procede de preparation d'acide hyaluronique reticule, acide hyaluronique reticule susceptible d'etre obtenu par ledit procede, implant contenant ledit acide hyaluronique reticule, et son utilisation
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
US20090088846A1 (en) 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
US7235592B2 (en) 2004-10-12 2007-06-26 Zimmer Gmbh PVA hydrogel
CA2588449A1 (en) * 2004-11-24 2006-06-01 Therakine Corporation An implant for intraocular drug delivery
EP2664334B1 (de) * 2004-12-30 2015-03-04 Genzyme Corporation Therapien zur intraartikulären Viskosupplementation
US7825083B2 (en) * 2005-02-10 2010-11-02 Spine Wave, Inc. Synovial fluid barrier
JP2008531769A (ja) 2005-02-23 2008-08-14 ズィマー・テクノロジー・インコーポレーテッド ブレンドヒドロゲルおよびその製造方法
US8828433B2 (en) * 2005-04-19 2014-09-09 Advanced Cardiovascular Systems, Inc. Hydrogel bioscaffoldings and biomedical device coatings
US20080125745A1 (en) 2005-04-19 2008-05-29 Shubhayu Basu Methods and compositions for treating post-cardial infarction damage
US9539410B2 (en) 2005-04-19 2017-01-10 Abbott Cardiovascular Systems Inc. Methods and compositions for treating post-cardial infarction damage
US7858080B2 (en) 2005-05-20 2010-12-28 Agency For Science, Technology And Research Aldehyde conjugated flavonoid preparations
AU2006266741B2 (en) 2005-07-06 2011-09-01 Seikagaku Corporation Drug-introduced photo-crosslinked hyaluronic acid derived gel
WO2007026362A2 (en) * 2005-09-02 2007-03-08 Colbar Lifescience Ltd. Cross-linked polysaccharide and protein matrices and methods for their preparation
CA2623106C (en) 2005-09-19 2013-12-24 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
EP1942957B1 (de) * 2005-10-27 2012-07-11 Coloplast A/S Biologisch abbaubares gerüst mit ecm-material
WO2007059890A1 (en) * 2005-11-22 2007-05-31 Centre National De Recherche Scientifique New derivatives of hyaluronic acid, their preparation process and their uses
WO2007067697A2 (en) 2005-12-07 2007-06-14 Zimmer, Inc. Methods of bonding or modifying hydrogels using irradiation
DE602006017160D1 (de) 2005-12-22 2010-11-11 Zimmer Inc Perfluorcyclobutanvernetzte Hydrogele
CA2645227C (en) 2006-03-07 2015-06-23 Prochon Biotech Ltd. Hydrazido derivatives of hyaluronic acid
US8110242B2 (en) 2006-03-24 2012-02-07 Zimmer, Inc. Methods of preparing hydrogel coatings
WO2007116143A1 (fr) * 2006-04-07 2007-10-18 Adocia Polysaccharides bifonctionnalises
US7674781B2 (en) * 2006-04-28 2010-03-09 Heather Sheardown Hyaluronic acid-retaining polymers
KR100803576B1 (ko) * 2006-06-14 2008-02-15 주식회사 인피트론 지방줄기세포 및 지방세포를 포함한 이식용 조성물
EP1884231A1 (de) * 2006-08-01 2008-02-06 Auriga International S.A. Kosmetische oder Pharmazeutische Zusammensetzung, die Hyaluronsäure enthält
US9242005B1 (en) 2006-08-21 2016-01-26 Abbott Cardiovascular Systems Inc. Pro-healing agent formulation compositions, methods and treatments
FR2908415B1 (fr) * 2006-11-10 2009-01-23 Abr Dev Sarl Acide hyaluronique reticule et son procede de preparation
US9005672B2 (en) 2006-11-17 2015-04-14 Abbott Cardiovascular Systems Inc. Methods of modifying myocardial infarction expansion
SI2107913T1 (sl) * 2006-12-22 2012-05-31 Croma Pharma Ges M B H Uporaba tioliranih polisaharidov za tkivno avgmentacijo
EP2106263B1 (de) * 2007-01-04 2016-12-21 Hepacore Ltd. Wasserlösliche und reaktive derivate von carboxy-polysacchariden und fibrinogen-konjugate daraus
EP2152743A2 (de) * 2007-05-23 2010-02-17 Allergan, Inc. Quervernetztes collagen und anwendungen davon
US20110077737A1 (en) * 2007-07-30 2011-03-31 Allergan, Inc. Tunably Crosslinked Polysaccharide Compositions
US7731988B2 (en) 2007-08-03 2010-06-08 Zimmer, Inc. Multi-polymer hydrogels
US8062739B2 (en) 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
US7947784B2 (en) 2007-11-16 2011-05-24 Zimmer, Inc. Reactive compounding of hydrogels
EP3498299A1 (de) 2007-11-16 2019-06-19 Aclaris Therapeutics, Inc. Zusammensetzungen und verfahren zur behandlung von purpura
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
CN101918032A (zh) * 2007-12-21 2010-12-15 恩希瑟有限公司 含有活性物质的交联水凝胶
US8034362B2 (en) 2008-01-04 2011-10-11 Zimmer, Inc. Chemical composition of hydrogels for use as articulating surfaces
EP2249891B1 (de) 2008-02-13 2016-05-25 The Cleveland Clinic Foundation Molekulare verstärkung von extrazellulärer matrix und anwendungsverfahren
US8668863B2 (en) 2008-02-26 2014-03-11 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
EP3456749B1 (de) 2008-02-29 2021-07-14 PVAC Medical Technologies Ltd. Substituiertes polyvinylalkohol-reagenz
US8410180B2 (en) 2008-04-30 2013-04-02 The Cleveland Clinic Foundation Methods to treat urinary incontinence
WO2009148985A2 (en) * 2008-06-03 2009-12-10 E. I. Du Pont De Nemours And Company A tissue coating for preventing undesired tissue-to-tissue adhesions
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
US20100015231A1 (en) * 2008-07-17 2010-01-21 E.I. Du Pont De Nemours And Company Low swell, long-lived hydrogel sealant
US8450475B2 (en) 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
EP2323670A4 (de) 2008-08-05 2013-12-25 Biomimedica Inc Polyurethan-gepfropfte hydrogele
JP5722217B2 (ja) 2008-09-02 2015-05-20 アラーガン・ホールディングス・フランス・ソシエテ・パール・アクシオン・サンプリフィエAllergan Holdings France S.A.S. ヒアルロン酸および/またはその誘導体の糸、その作製方法、ならびにその使用
DE102008048227A1 (de) 2008-09-18 2010-04-01 Friedrich-Schiller-Universität Jena Verfahren zur Generierung von formstabilen Polyelektrolythydrogel-Körpern mit definierter dreidimensionaler Gestalt sowie deren Verwendung
ES2829956T3 (es) 2008-10-02 2021-06-02 Lrr & D Ltd Apósito para heridas en capa de interfaz
CN101721349B (zh) 2008-10-16 2011-07-20 常州百瑞吉生物医药有限公司 可注射原位交联水凝胶及其制备方法和用途
WO2010059279A2 (en) * 2008-11-19 2010-05-27 E. I. Du Pont De Nemours And Company Hydrogel tissue adhesive formed from aminated polysaccharide and aldehyde-functionalized multi-arm polyether
US20100160960A1 (en) * 2008-12-19 2010-06-24 E. I. Du Pont De Nemours And Company Hydrogel tissue adhesive having increased degradation time
US8273373B2 (en) * 2008-12-30 2012-09-25 Case Western Reserve University Photocrosslinked biodegradable hydrogel
US8968733B2 (en) 2009-02-21 2015-03-03 Sofradim Production Functionalized surgical adhesives
CA2757557C (en) * 2009-04-02 2017-06-27 Allergan, Inc. Hair-like shaped hydrogels for soft tissue augmentation
US8951989B2 (en) 2009-04-09 2015-02-10 Actamax Surgical Materials, Llc Hydrogel tissue adhesive having reduced degradation time
KR101100803B1 (ko) * 2009-04-24 2011-12-29 서울과학기술대학교 산학협력단 리포아마이드가 결합된 고분자화합물과 이의 제조방법
SG10201402723QA (en) 2009-05-29 2014-10-30 Agency Science Tech & Res Flavonoid hydrogel
WO2010138074A1 (en) * 2009-05-29 2010-12-02 Hilborn Joens Hyaluronic acid based delivery systems
IT1399351B1 (it) 2009-06-16 2013-04-16 Fidia Farmaceutici Procedimento per la sintesi di coniugati di glicosamminoglicani (gag) con molecole biologicamente attive, coniugati polimerici e usi relativi
US8796242B2 (en) 2009-07-02 2014-08-05 Actamax Surgical Materials, Llc Hydrogel tissue adhesive for medical use
US8778326B2 (en) 2009-07-02 2014-07-15 Actamax Surgical Materials, Llc Hydrogel tissue adhesive for medical use
US8580951B2 (en) * 2009-07-02 2013-11-12 Actamax Surgical Materials, Llc Aldehyde-functionalized polysaccharides
KR20120100962A (ko) 2009-10-02 2012-09-12 박스터 헬쓰케어 에스.에이. 신장 손상을 치료하는데 사용하기 위한 조혈 줄기 세포
US20120264689A1 (en) 2009-10-07 2012-10-18 Genogen, Inc. Methods and compositions for skin regeneration
CA2780274C (en) 2009-11-09 2018-06-26 Spotlight Technology Partners Llc Fragmented hydrogels
WO2011057131A1 (en) 2009-11-09 2011-05-12 Spotlight Technology Partners Llc Polysaccharide based hydrogels
WO2011059325A2 (en) * 2009-11-11 2011-05-19 University Of Twente, Institute For Biomedical Technology And Technical Medicine (Mira) Dextran-hyaluronic acid based hydrogels
EP3067069B1 (de) * 2009-11-11 2023-07-26 Hy2Care B.V. Hydrogele auf der basis von dextrantyramin und tyraminkonjugaten aus natürlichen polymeren
WO2011065916A1 (en) 2009-11-24 2011-06-03 Agency For Science, Technology And Research Crosslinking branched molecule through thiol-disulfide exchange to form hydrogel
JP4810628B2 (ja) * 2009-12-08 2011-11-09 キユーピー株式会社 精製ヒアルロン酸類の製造方法
CZ302503B6 (cs) 2009-12-11 2011-06-22 Contipro C A.S. Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace
CZ302504B6 (cs) 2009-12-11 2011-06-22 Contipro C A.S. Derivát kyseliny hyaluronové oxidovaný v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd, zpusob jeho prípravy a zpusob jeho modifikace
FR2954945B1 (fr) 2010-01-04 2012-01-06 Oreal Composition cosmetique ou dermatologique, procede de traitement cosmetique et derive d'acide hyaluronique
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
CA2792729C (en) 2010-03-12 2016-06-28 Allergan Industrie, Sas Fluid compositions for improving skin conditions
HUE030138T2 (en) 2010-03-22 2017-04-28 Allergan Inc Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation
US9012415B2 (en) 2010-03-26 2015-04-21 Stemmatters, Biotecnologia E Medicina Regenerativa S.A. Photo-crosslinked gellan gum-based hydrogels: preparation methods and uses thereof
JP2013523752A (ja) * 2010-03-29 2013-06-17 エボニック デグサ コーポレイション 局所投与部位における医薬組成物の保持改善のための組成物および方法
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US20130217829A1 (en) 2010-08-27 2013-08-22 David Myung "hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same"
CN102399295B (zh) 2010-09-09 2013-11-06 常州百瑞吉生物医药有限公司 低巯基化改性度生物相容高分子巯基化衍生物及其交联材料和用途
JP6042815B2 (ja) 2010-10-08 2016-12-14 ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム 生物医学的応用のためのアルギン酸塩及びヒアルロン酸を用いる抗癒着性バリア膜
WO2012048283A1 (en) 2010-10-08 2012-04-12 Board Of Regents, The University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
EP2630196B1 (de) 2010-10-20 2017-09-06 Li-Cor, Inc. Cyaninfarbstoffe und deren konjugate
US8524662B2 (en) 2010-12-28 2013-09-03 Depuy Mitek, Llc Compositions and methods for treating joints
US8455436B2 (en) 2010-12-28 2013-06-04 Depuy Mitek, Llc Compositions and methods for treating joints
US8398611B2 (en) 2010-12-28 2013-03-19 Depuy Mitek, Inc. Compositions and methods for treating joints
EP2670439B1 (de) * 2011-01-31 2019-03-13 PVAC Medical Technologies Ltd. Wirkstoff zur abschwächung unerwünschter medizinischer zustände
EP2682409B1 (de) * 2011-03-03 2017-07-05 Chugai Seiyaku Kabushiki Kaisha Durch aminocarbonsäure modifiziertes hyaluronsäurederivat
WO2012140650A2 (en) 2011-04-12 2012-10-18 Hepacore Ltd. Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof
US9492383B2 (en) 2011-04-20 2016-11-15 Carbylan Therapeutics, Inc. Rapid in-situ gel forming compositions prepared via reaction of vinyl sulfone derivatized hyaluronic acid with thiol derivatized polyethylene glycol at alkaline pH
WO2012165462A1 (ja) * 2011-05-31 2012-12-06 国立大学法人 東京大学 ハイドロゲル及びその製造方法
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US20220023186A1 (en) * 2011-06-03 2022-01-27 Allergan, Inc. Dermal filler compositions
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
AU2012262047A1 (en) 2011-06-03 2014-01-16 Allergan, Inc. Dermal filler compositions including antioxidants
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US8623839B2 (en) 2011-06-30 2014-01-07 Depuy Mitek, Llc Compositions and methods for stabilized polysaccharide formulations
WO2013010045A1 (en) 2011-07-12 2013-01-17 Biotime Inc. Novel methods and formulations for orthopedic cell therapy
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
TW201322988A (zh) * 2011-09-08 2013-06-16 Shin Poong Pharmaceutical Co 關節炎之治療注射劑
AU2015255254B2 (en) * 2011-09-14 2017-07-06 Allergan Industrie, Sas Dermal filler compositions for fine line treatment
WO2013052105A2 (en) 2011-10-03 2013-04-11 Biomimedica, Inc. Polymeric adhesive for anchoring compliant materials to another surface
TWI561535B (en) 2011-10-06 2016-12-11 Bvw Holding Ag Copolymers of hydrophobic and hydrophilic segments that reduce protein adsorption
AU2012340699A1 (en) 2011-11-21 2014-06-19 Biomimedica, Inc. Systems, devices, and methods for anchoring orthopaedic implants to bone
IN2014DN06200A (de) * 2012-01-25 2015-10-23 Univ Akron
WO2013126590A2 (en) 2012-02-21 2013-08-29 Baxter International Inc. Pharmaceutical composition comprising cd34+ cells
CZ2012136A3 (cs) * 2012-02-28 2013-06-05 Contipro Biotech S.R.O. Deriváty na bázi kyseliny hyaluronové schopné tvorit hydrogely, zpusob jejich prípravy, hydrogely na bázi techto derivátu, zpusob jejich prípravy a pouzití
CZ304512B6 (cs) * 2012-08-08 2014-06-11 Contipro Biotech S.R.O. Derivát kyseliny hyaluronové, způsob jeho přípravy, způsob jeho modifikace a použití
CZ2012842A3 (cs) 2012-11-27 2014-08-20 Contipro Biotech S.R.O. Nanomicelární kompozice na bázi C6-C18-acylovaného hyaluronanu, způsob přípravy C6-C18-acylovaného hyaluronanu, způsob přípravy nanomicelární kompozice a stabilizované nanomicelární kompozice a použití
CZ304266B6 (cs) 2012-11-27 2014-02-05 Contipro Biotech S.R.O. Nekonečná vlákna na bázi hyaluronanu selektivně oxidovaného v poloze 6 N-acetyl-D-glukosaminové části, jejich příprava, použití, nitě, střiže, příze, textilie a způsob jejich úpravy
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
JP6242910B2 (ja) 2012-12-11 2017-12-06 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム 癒着防止のためのハイドロゲル膜
US20140315828A1 (en) 2013-04-22 2014-10-23 Allergan, Inc. Cross-linked silk-hyaluronic acid compositions
WO2015017340A2 (en) 2013-07-29 2015-02-05 Actamax Surgical Materials, Llc Low swell tissue adhesive and sealant formulations
US9782345B2 (en) 2013-10-17 2017-10-10 Jade Therapeutics, Inc. Ocular composition and method
CZ2014150A3 (cs) 2014-03-11 2015-05-20 Contipro Biotech S.R.O. Konjugáty oligomeru kyseliny hyaluronové nebo její soli, způsob jejich přípravy a použití
US20170072096A1 (en) * 2014-03-16 2017-03-16 Drexel University Novel hydrogels and methods using same
CZ2014451A3 (cs) 2014-06-30 2016-01-13 Contipro Pharma A.S. Protinádorová kompozice na bázi kyseliny hyaluronové a anorganických nanočástic, způsob její přípravy a použití
WO2016051219A1 (en) 2014-09-30 2016-04-07 Allergan Industrie, Sas Stable hydrogel compositions including additives
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
EP3040348A1 (de) * 2014-12-29 2016-07-06 Galderma S.A. Pfropfcopolymer
US9682099B2 (en) 2015-01-20 2017-06-20 DePuy Synthes Products, Inc. Compositions and methods for treating joints
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
EP3653232A1 (de) 2015-02-13 2020-05-20 Allergan Industrie, SAS Implantate zur formung, verstärkung oder korrektur von gesichtszügen wie etwa dem kinn
CZ309295B6 (cs) 2015-03-09 2022-08-10 Contipro A.S. Samonosný, biodegradabilní film na bázi hydrofobizované kyseliny hyaluronové, způsob jeho přípravy a použití
CZ306479B6 (cs) 2015-06-15 2017-02-08 Contipro A.S. Způsob síťování polysacharidů s využitím fotolabilních chránicích skupin
CZ306662B6 (cs) 2015-06-26 2017-04-26 Contipro A.S. Deriváty sulfatovaných polysacharidů, způsob jejich přípravy, způsob jejich modifikace a použití
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
US10563164B1 (en) 2015-10-08 2020-02-18 Charm Sciences, Inc. Plate reader
EP3156044A1 (de) 2015-10-16 2017-04-19 Merz Pharma GmbH & Co. KGaA In-situ-vernetzbare polysaccharidzusammensetzungen und verwendungen davon
DK4279537T3 (da) 2015-12-29 2026-04-20 Galderma Holding SA Kulhydrat-tværbinder
US10495563B1 (en) 2016-04-28 2019-12-03 Charm Sciences, Inc. Plate reader observation methods and operation
EP3241895A1 (de) * 2016-05-04 2017-11-08 ETH Zürich, ETH Transfer Transglutaminasevermittelte hyaluronanhydrogele mit hohem molekulargewicht
PT3623390T (pt) * 2016-05-31 2023-10-27 Galderma Sa Reticulador de hidrato de carbono
US11491233B2 (en) * 2016-06-13 2022-11-08 Purdue Research Foundation Responsive elastic polymers and methods of making and using same
CZ308106B6 (cs) 2016-06-27 2020-01-08 Contipro A.S. Nenasycené deriváty polysacharidů, způsob jejich přípravy a jejich použití
AU2017315431B2 (en) 2016-08-24 2020-06-25 Allergan, Inc. Co-crosslinked hyaluronic acid-silk fibroin hydrogels for improving tissue graft viability and for soft tissue augmentation
WO2018067545A1 (en) * 2016-10-04 2018-04-12 University Of Florida Research Foundation, Inc. Chondroprotective nanoparticles for the treatment of osteoarthritis
KR101877894B1 (ko) * 2016-12-09 2018-07-12 서울대학교병원 난청 치료용 복합 주사 제제 및 그의 제조 방법
WO2018165327A1 (en) 2017-03-08 2018-09-13 Alafair Biosciences, Inc. Hydrogel medium for the storage and preservation of tissue
IL269506B2 (en) 2017-03-22 2024-04-01 Genentech Inc Hydrogel cross-linked hyaluronic acid prodrug compositions and methods
US11129790B2 (en) 2017-05-19 2021-09-28 Northeastern University Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates
US20230190997A1 (en) 2017-06-26 2023-06-22 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue filers and methods of using the same
SG11201913229PA (en) 2017-06-26 2020-01-30 Evolved By Nature Inc Silk-hyaluronic acid based tissue fillers and methods of using the same
WO2019121488A1 (en) * 2017-12-21 2019-06-27 Nicox S.A. Nitric oxide releasing hyaluronic esters
CN108721695A (zh) * 2018-05-29 2018-11-02 金陵科技学院 一种可注射性复合水凝胶细胞载体支架的制备方法
EP3806917B1 (de) 2018-06-15 2025-12-10 Croma-Pharma GmbH Hydrogelzusammensetzung umfassend ein quervernetztes polymer
JP7374133B2 (ja) 2018-06-15 2023-11-06 クロマ-ファーマ ゲゼルシャフト エム.ベー.ハー. 安定化されたヒアルロン酸
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions
WO2020132331A1 (en) 2018-12-19 2020-06-25 Evolved By Nature, Inc. Silk-hyaluronic acid tissue fillers and methods of making and using the same
EP3898703A1 (de) 2018-12-19 2021-10-27 Merz Pharma GmbH & Co. KGaA Aldehydmodifizierte hyaluronsäure, verfahren zur herstellung davon und anwendungen davon
US11667895B2 (en) 2019-05-10 2023-06-06 The Board Of Trustees Of The University Of Alabama Methods and devices related to controlled delivery of phages as a theranostic tool
CN110279610B (zh) 2019-06-26 2021-06-11 常州百瑞吉生物医药有限公司 一种透明质酸皮肤保护组合物及其制备方法和应用
EP3994183A4 (de) * 2019-07-03 2023-07-26 Molly Sandra Shoichet Hydrogeldzusammensetzungen und verwendungen davon
EP4069753A1 (de) 2019-12-02 2022-10-12 Galderma Holding SA Ästhetische zusammensetzungen mit hohem molekulargewicht
EP4077402B1 (de) 2019-12-19 2024-05-01 Croma-Pharma GmbH Thiolmodifiziertes hyaluronan und hydrogel mit dem vernetzten hyaluronan
CN113929792B (zh) * 2020-07-13 2023-03-10 孛朗孚(杭州)生物科技有限公司 一种醛基化修饰的透明质酸(钠)及其合成方法和应用
CN113583262B (zh) * 2021-06-24 2022-03-29 四川大学 用于关节软骨修复的近红外响应透明质酸水凝胶及其制备方法
WO2024124189A1 (en) * 2022-12-08 2024-06-13 The General Hospital Corporation Corneal filler
EP4654940A1 (de) * 2023-01-27 2025-12-03 Tempo Therapeutics, Inc. Geglühte mikrogelteilchensysteme und verfahren
EP4567050A1 (de) 2023-12-04 2025-06-11 Quantum Beauty Cosmetics Joint Stock Company Verfahren zur herstellung eines vernetzten hyaluronsäuregels

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166331A (en) 1983-10-10 1992-11-24 Fidia, S.P.A. Hyaluronics acid fractions, methods for the preparation thereof, and pharmaceutical compositions containing same
US5512329A (en) * 1982-09-29 1996-04-30 Bsi Corporation Substrate surface preparation
US4517295A (en) 1983-02-18 1985-05-14 Diagnostic, Inc. Hyaluronic acid from bacterial culture
US5316926A (en) 1983-11-25 1994-05-31 Miles Inc. Method for the microbiological production of non-antigenic hyaluronic acid
MX163953B (es) 1984-03-27 1992-07-03 Univ New Jersey Med Procedimiento para preparar una matriz biodegradable a base de colageno
JPS60251898A (ja) 1984-05-25 1985-12-12 Shiseido Co Ltd 醗酵法によるヒアルロン酸の製造方法
US4582865A (en) 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4780414A (en) 1985-01-18 1988-10-25 Bio-Technology General Corp. Method of producing high molecular weight sodium hyallronate by fermentation of streptococcus
US4713448A (en) 1985-03-12 1987-12-15 Biomatrix, Inc. Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues
US4851521A (en) 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
DE3608158A1 (de) 1986-03-12 1987-09-17 Braun Melsungen Ag Mit vernetzter gelatine impraegnierte gefaessprothese und verfahren zu ihrer herstellung
IT1198449B (it) 1986-10-13 1988-12-21 F I D I Farmaceutici Italiani Esteri di alcoli polivalenti di acido ialuronico
US6174999B1 (en) * 1987-09-18 2001-01-16 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US5017229A (en) 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US5527893A (en) 1987-09-18 1996-06-18 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
FI912858A0 (fi) 1988-12-20 1991-06-13 Jolla Cancer Res Found Polypeptidpolymerkonjugat aktiva vid botande av saor.
US4897349A (en) 1989-04-28 1990-01-30 Medchem Products, Inc. Biosynthesis of hyaluronic acid
US5356883A (en) 1989-08-01 1994-10-18 Research Foundation Of State University Of N.Y. Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
CA2070672C (en) * 1990-10-18 2002-10-08 Kazuo Akima Compound of medicinal ingredient and hyaluronic acid and process for producing the same
US5206023A (en) 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
US5219360A (en) * 1991-05-10 1993-06-15 Fortis Research Corporation Mammary prosthesis fill and method of making same
JP3351525B2 (ja) * 1991-06-21 2002-11-25 ジェネティックス・インスティテュート・インコーポレイテッド 骨形成性蛋白医薬処方物
FR2679778B1 (fr) 1991-08-02 1995-07-07 Coletica Utilisation de collagene reticule par un agent de reticulation pour la fabrication d'une membrane suturable, biocompatible, a resorption lente, ainsi qu'une telle membrane.
US5270300A (en) 1991-09-06 1993-12-14 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone
GB2261672A (en) 1991-11-18 1993-05-26 Michael Braden The use of biomaterials for tissue repair
JP2855307B2 (ja) * 1992-02-05 1999-02-10 生化学工業株式会社 光反応性グリコサミノグリカン、架橋グリコサミノグリカン及びそれらの製造方法
GB9206509D0 (en) 1992-03-25 1992-05-06 Jevco Ltd Heteromorphic sponges containing active agents
IL105529A0 (en) 1992-05-01 1993-08-18 Amgen Inc Collagen-containing sponges as drug delivery for proteins
US5565210A (en) 1993-03-22 1996-10-15 Johnson & Johnson Medical, Inc. Bioabsorbable wound implant materials
US5616568A (en) * 1993-11-30 1997-04-01 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
IT1268955B1 (it) * 1994-03-11 1997-03-18 Fidia Advanced Biopolymers Srl Esteri attivi di polisaccaridi carbossilici
US5769899A (en) 1994-08-12 1998-06-23 Matrix Biotechnologies, Inc. Cartilage repair unit
US6025444A (en) * 1994-11-17 2000-02-15 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Cinnamic acid derivative
IT1269274B (it) 1994-11-22 1997-03-26 Carlo Antonio Camorani Metodo per la formatura di piastrelle ceramiche ed impianto relativo
US5693341A (en) 1995-03-16 1997-12-02 Collagen Corporation Affinity bound collagen matrices for the delivery of biologically active agents
US5817303A (en) * 1995-05-05 1998-10-06 Protein Polymer Technologies, Inc. Bonding together tissue with adhesive containing polyfunctional crosslinking agent and protein polymer
WO1997018244A1 (en) 1995-11-15 1997-05-22 Seikagaku Corporation Photocured cross-linked-hyaluronic acid gel and method of preparation thereof
EP0907721A1 (de) 1996-05-28 1999-04-14 Brown University Research Foundation Biologisch abbaubarer träger auf basis von hyaluronan für die gewebewiederherstellung
FR2754267B1 (fr) 1996-10-07 1999-01-22 Dev Des Utilisations Du Collag Procede de reticulation de collagene ou de gelatine a l'aide d'un polyaldehyde macromoleculaire et composition adhesive
JP2002512942A (ja) * 1998-04-28 2002-05-08 ヤーゴウテック アーゲー ヒアルロナン系像形成剤
AU752280C (en) * 1998-05-20 2005-03-03 Chugai Seiyaku Kabushiki Kaisha Conjugate of therapeutic agent for joint disease and hyaluronic acid.

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IL142068A (en) 2006-10-05
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CA2344215A1 (en) 2000-03-30
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