IL142668A - Method of preparing delta-9-tetrahydrocannabinol esters - Google Patents

Method of preparing delta-9-tetrahydrocannabinol esters

Info

Publication number: IL142668A
Authority: IL; Israel
Prior art keywords: tetrahydrocannabinol; esters; delta; preparing delta; preparing
Prior art date: 1998-10-26

Application number

IL14266899A

Other languages

English (en)

Other versions

IL142668A0 (en

Original Assignee

Univ Mississippi

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-10-26

Filing date

1999-10-26

Publication date

2005-03-20

1999-10-26 Application filed by Univ Mississippi filed Critical Univ Mississippi

2002-03-10 Publication of IL142668A0 publication Critical patent/IL142668A0/xx

2005-03-20 Publication of IL142668A publication Critical patent/IL142668A/xx

Links

CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical class C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 title abstract 3
XXGMIHXASFDFSM-UHFFFAOYSA-N Delta9-tetrahydrocannabinol Natural products CCCCCc1cc2OC(C)(C)C3CCC(=CC3c2c(O)c1O)C XXGMIHXASFDFSM-UHFFFAOYSA-N 0.000 abstract 2
CYQFCXCEBYINGO-UHFFFAOYSA-N THC Natural products C1=C(C)CCC2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3C21 CYQFCXCEBYINGO-UHFFFAOYSA-N 0.000 abstract 2
NUKYPUAOHBNCPY-UHFFFAOYSA-N 4-aminopyridine Chemical compound NC1=CC=NC=C1 NUKYPUAOHBNCPY-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000008065 acid anhydrides Chemical class 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
229960004979 fampridine Drugs 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
125000005270 trialkylamine group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrane Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IL14266899A 1998-10-26 1999-10-26 Method of preparing delta-9-tetrahydrocannabinol esters IL142668A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/178,644 US6008383A (en)	1998-10-26	1998-10-26	Method of preparing delta-9-tetrahydrocannabinol esters
PCT/US1999/025141 WO2000029402A1 (en)	1998-10-26	1999-10-26	Method of preparing delta-9-tetrahydrocannabinol esters

Publications (2)

Publication Number	Publication Date
IL142668A0 IL142668A0 (en)	2002-03-10
IL142668A true IL142668A (en)	2005-03-20

Family

ID=22653334

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL14266899A IL142668A (en)	1998-10-26	1999-10-26	Method of preparing delta-9-tetrahydrocannabinol esters

Country Status (25)

Country	Link
US (1)	US6008383A (de)
EP (1)	EP1124817B1 (de)
JP (1)	JP2002530279A (de)
KR (1)	KR100711951B1 (de)
CN (1)	CN1158275C (de)
AT (1)	ATE279405T1 (de)
AU (1)	AU770382B2 (de)
BR (1)	BR9914787A (de)
CA (1)	CA2348695C (de)
CZ (1)	CZ20011436A3 (de)
DE (1)	DE69921170T2 (de)
DK (1)	DK1124817T3 (de)
ES (1)	ES2232208T3 (de)
GB (1)	GB2358397A (de)
HU (1)	HU226777B1 (de)
IL (1)	IL142668A (de)
MX (1)	MXPA01004125A (de)
NO (1)	NO327128B1 (de)
NZ (1)	NZ511236A (de)
PL (1)	PL196944B1 (de)
PT (1)	PT1124817E (de)
RU (1)	RU2232759C2 (de)
SK (1)	SK5442001A3 (de)
WO (1)	WO2000029402A1 (de)
ZA (1)	ZA200103168B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6008383A (en) *	1998-10-26	1999-12-28	University Of Mississippi	Method of preparing delta-9-tetrahydrocannabinol esters
WO2000045813A1 (en) *	1999-02-04	2000-08-10	New Millennium Pharmaceutical Research, Inc.	Method for enhancement of delivery of thc by the administration of its prodrugs via the nasal route
EP1321159A1 (de)	2001-12-21	2003-06-25	CHIESI FARMACEUTICI S.p.A.	Betätigungsvorrichtung für Druckdosierinhalator mit lasergebohrten Löchern
MXPA05004966A (es) *	2002-11-12	2005-08-02	Mallinckrodt Inc	Derivados cristalinos de canabinoide y procesos de purificacion de canabinoide.
US20060051824A1 (en) *	2004-09-03	2006-03-09	Haoyun An	Tetrahydrocannabinoid antigens and method of use
EP1827393A4 (de) *	2004-12-09	2012-04-18	Insys Therapeutics Inc	Bei raumtemperatur stabile dronabinol-formulierungen
CA2623723A1 (en) *	2005-09-29	2007-04-12	Amr Technology, Inc.	Process for production of delta-9-tetrahydrocannabinol
WO2008019146A2 (en) *	2006-08-04	2008-02-14	Insys Therapeutics Inc.	Aqueous dronabinol formulations
CN101668425A (zh)	2007-03-02	2010-03-10	田纳西州立大学研究基金会	三芳基/杂芳族大麻素类和其应用
JP2010535774A (ja) *	2007-08-06	2010-11-25	インシスセラピューティクスインコーポレイテッド	経口カンナビノイド液体製剤および治療方法
HUE032158T2 (en) *	2008-10-31	2017-09-28	Univ Mississippi	Process for the preparation of delta9-THC amino acid esters
US10239808B1 (en)	2016-12-07	2019-03-26	Canopy Holdings, LLC	Cannabis extracts
CA3089994A1 (en)	2018-01-31	2019-08-08	Canopy Holdings, LLC	Hemp powder
WO2020077153A1 (en)	2018-10-10	2020-04-16	Canopy Holdings, LLC	Synthesis of cannabigerol
US10569189B1 (en) *	2019-05-17	2020-02-25	NextLeaf Solutions Ltd.	Method for acetylation of cannabinoids
US10954209B1 (en) *	2019-09-15	2021-03-23	NextLeaf Solutions Ltd.	Acetylation of cannabinoids using sulfuric acid catalyst
EP4089081B1 (de) *	2020-01-08	2025-07-23	Chengdu Baiyu Pharmaceutical Co., Ltd.	Tetrahydrocannabinol-derivat, und herstellungsverfahren dafür und medizinische verwendung davon
WO2021139739A1 (zh)	2020-01-08	2021-07-15	成都百裕制药股份有限公司	大麻二酚衍生物及其制备方法和在医药上的应用
CN115605195A (zh)	2020-03-04	2023-01-13	普利欧制药有限公司（Us）	用于治疗大麻使用病症和缓解大麻素戒断的方法和组合物
US12029718B2 (en)	2021-11-09	2024-07-09	Cct Sciences, Llc	Process for production of essentially pure delta-9-tetrahydrocannabinol

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3728360A (en) *	1971-08-31	1973-04-17	Little Inc A	Ester derivatives of tetrahydrocannabinol
US4933633A (en) *	1981-06-09	1990-06-12	Adec, Inc.	Computer controlled energy monitoring system
US4933363A (en) *	1988-08-16	1990-06-12	Elsohly Mahmoud A	Method for effecting systemic delivery of delta-9-tetrahydrocannabinol
US5389375A (en) *	1993-05-21	1995-02-14	University Of Mississippi	Stable suppository formulations effecting bioavailability of Δ9 -thc
RU2106350C1 (ru) *	1996-01-16	1998-03-10	Научно-исследовательский институт физической и органической химии Ростовского государственного университета	Производные 8,9-дигидроксантена и способ их получения
US6008383A (en) *	1998-10-26	1999-12-28	University Of Mississippi	Method of preparing delta-9-tetrahydrocannabinol esters

1998
- 1998-10-26 US US09/178,644 patent/US6008383A/en not_active Expired - Lifetime
1999
- 1999-10-26 CN CNB998150606A patent/CN1158275C/zh not_active Expired - Fee Related
- 1999-10-26 DK DK99972211T patent/DK1124817T3/da active
- 1999-10-26 NZ NZ511236A patent/NZ511236A/xx unknown
- 1999-10-26 HU HU0104776A patent/HU226777B1/hu not_active IP Right Cessation
- 1999-10-26 EP EP99972211A patent/EP1124817B1/de not_active Expired - Lifetime
- 1999-10-26 CA CA002348695A patent/CA2348695C/en not_active Expired - Fee Related
- 1999-10-26 PT PT99972211T patent/PT1124817E/pt unknown
- 1999-10-26 WO PCT/US1999/025141 patent/WO2000029402A1/en not_active Ceased
- 1999-10-26 KR KR1020017005204A patent/KR100711951B1/ko not_active Expired - Fee Related
- 1999-10-26 ES ES99972211T patent/ES2232208T3/es not_active Expired - Lifetime
- 1999-10-26 RU RU2001114197/04A patent/RU2232759C2/ru not_active IP Right Cessation
- 1999-10-26 AU AU12349/00A patent/AU770382B2/en not_active Ceased
- 1999-10-26 PL PL348118A patent/PL196944B1/pl not_active IP Right Cessation
- 1999-10-26 IL IL14266899A patent/IL142668A/xx not_active IP Right Cessation
- 1999-10-26 MX MXPA01004125A patent/MXPA01004125A/es not_active IP Right Cessation
- 1999-10-26 CZ CZ20011436A patent/CZ20011436A3/cs unknown
- 1999-10-26 DE DE69921170T patent/DE69921170T2/de not_active Expired - Fee Related
- 1999-10-26 AT AT99972211T patent/ATE279405T1/de not_active IP Right Cessation
- 1999-10-26 GB GB0109941A patent/GB2358397A/en not_active Withdrawn
- 1999-10-26 SK SK544-2001A patent/SK5442001A3/sk unknown
- 1999-10-26 JP JP2000582389A patent/JP2002530279A/ja active Pending
- 1999-10-26 BR BR9914787-4A patent/BR9914787A/pt not_active Application Discontinuation
2001
- 2001-04-18 ZA ZA200103168A patent/ZA200103168B/en unknown
- 2001-04-23 NO NO20011999A patent/NO327128B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
HUP0104776A3 (en)	2003-01-28
CA2348695C (en)	2009-12-29
KR20010085959A (ko)	2001-09-07
NZ511236A (en)	2002-11-26
CN1331687A (zh)	2002-01-16
AU770382B2 (en)	2004-02-19
DE69921170T2 (de)	2006-02-16
AU1234900A (en)	2000-06-05
DK1124817T3 (da)	2005-02-07
PT1124817E (pt)	2005-02-28
NO20011999D0 (no)	2001-04-23
BR9914787A (pt)	2001-07-03
HU226777B1 (en)	2009-09-28
NO327128B1 (no)	2009-04-27
EP1124817B1 (de)	2004-10-13
CZ20011436A3 (cs)	2001-10-17
ATE279405T1 (de)	2004-10-15
CN1158275C (zh)	2004-07-21
WO2000029402A1 (en)	2000-05-25
US6008383A (en)	1999-12-28
ES2232208T3 (es)	2005-05-16
PL196944B1 (pl)	2008-02-29
EP1124817A4 (de)	2002-03-27
GB2358397A (en)	2001-07-25
GB0109941D0 (en)	2001-06-13
PL348118A1 (en)	2002-05-06
KR100711951B1 (ko)	2007-05-02
CA2348695A1 (en)	2000-05-25
JP2002530279A (ja)	2002-09-17
RU2232759C2 (ru)	2004-07-20
NO20011999L (no)	2001-06-18
DE69921170D1 (de)	2004-11-18
HK1042088A1 (en)	2002-08-02
HUP0104776A2 (hu)	2002-04-29
SK5442001A3 (en)	2001-11-06
ZA200103168B (en)	2002-07-18
EP1124817A1 (de)	2001-08-22
MXPA01004125A (es)	2002-04-08
IL142668A0 (en)	2002-03-10

Legal Events

Date	Code	Title
2005-09-25	FF	Patent granted
2005-09-25	KB	Patent renewed
2006-01-15	KB	Patent renewed
2010-11-30	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
IL142668A0 (en)	2002-03-10	Method of preparing delta-9-tetrahydrocannabinol esters
MXPA03010183A (es)	2004-03-16	Proceso para preparar acidos carboxilicos y derivados de los mismos.
MY110715A (en)	1999-01-30	Esterification process
MY129065A (en)	2007-03-30	Flexible method for the common production of formic acid, a carboxylic acid having at least two carbon atoms, and/or the derivatives of the same
YU71100A (sh)	2002-10-18	Postupak za dobijanje alkil karboksilnih kiselina karboksilacijom nižih alkan metana
KR840001531A (ko)	1984-05-07	입상 고로슬랙용 분쇄보조제
DE3378206D1 (en)	1988-11-17	Process for the preparation of a free alpha-l-amino acid
AU7230994A (en)	1995-02-06	Process for the synthesis of nucleic acids on a solid support and compounds which are useful in particular as solid supports in the said process
HUT77183A (hu)	1998-03-02	Eljárás 2,6-diizopropil-fenol tisztítására
PL352359A1 (en)	2003-08-11	Method of making (nitroxymethylo)phenyl esters, derivatives of salicylic acid
AU2001246462A1 (en)	2001-09-17	Method for the synthesis of straight-chain aliphatic carboxylic acids from aldehydes
TW265344B (de)	1995-12-11
WO1993009111A3 (en)	1993-10-28	Novel methods for the preparation of glycerol carbonate esters
EP0269453A3 (en)	1988-08-10	A process for producing carboxylic acid esters
MY127267A (en)	2006-11-30	Method for producing esters of (alpha), ?-unsaturated carboxylic acids
ES2148667T3 (es)	2000-10-16	Procedimiento para la carbonilacion de butadieno o un derivado de butadieno.
ATE340265T1 (de)	2006-10-15	Verfahren zur reduktion von ketogruppen enthaltende verbindungen
HU9902855D0 (en)	1999-10-28	Preparation of sterol- and stanol-esters
RU95102320A (ru)	1996-11-20	Способ очистки сырого n-винилпирролид-2-она
AU2002221913A1 (en)	2002-06-24	Method for producing cinnamic acid esters
ES2095144T3 (es)	1997-02-01	Procedimiento mejorado para preparacion de l-(-)-carnitina a partir de un producto de desecho que tiene configuracion opuesta.
RU95109862A (ru)	1997-04-20	Способ выделения алифатических насыщенных дикислот с 6 атомами углерода из их смесей с адипиновой кислотой
MXPA02005084A (es)	2004-08-23	Procedimiento para fabricar tienopirimidinas.
MY133389A (en)	2007-11-30	Process for preparing aromatic carboxylic acids with efficient treatments of gaseous effluent
JPS57139035A (en)	1982-08-27	Preparation of ethynyl carbinol ester