IL142989A0 - Nucleotide and protein sequences of nogo genes and methods based thereon - Google Patents

Nucleotide and protein sequences of nogo genes and methods based thereon

Info

Publication number
IL142989A0
IL142989A0 IL14298999A IL14298999A IL142989A0 IL 142989 A0 IL142989 A0 IL 142989A0 IL 14298999 A IL14298999 A IL 14298999A IL 14298999 A IL14298999 A IL 14298999A IL 142989 A0 IL142989 A0 IL 142989A0
Authority
IL
Israel
Prior art keywords
nucleotide
protein sequences
methods based
nogo
nogo genes
Prior art date
Application number
IL14298999A
Other languages
English (en)
Inventor
Martin E Schwab
Maio S Chen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22316666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL142989(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of IL142989A0 publication Critical patent/IL142989A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
IL14298999A 1998-11-06 1999-11-05 Nucleotide and protein sequences of nogo genes and methods based thereon IL142989A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10744698P 1998-11-06 1998-11-06
PCT/US1999/026160 WO2000031235A2 (fr) 1998-11-06 1999-11-05 Sequences nucleotidiques et proteiques de gene nogo et procedes reposant sur ces sequences

Publications (1)

Publication Number Publication Date
IL142989A0 true IL142989A0 (en) 2002-04-21

Family

ID=22316666

Family Applications (3)

Application Number Title Priority Date Filing Date
IL14298999A IL142989A0 (en) 1998-11-06 1999-11-05 Nucleotide and protein sequences of nogo genes and methods based thereon
IL142989A IL142989A (en) 1998-11-06 2001-05-06 Nucleotide and protein sequences of nogo genes and methods based thereon
IL198027A IL198027A (en) 1998-11-06 2009-04-06 Antibody of the NOGO gene, medicinal preparations containing the antibody and use of the antibody

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL142989A IL142989A (en) 1998-11-06 2001-05-06 Nucleotide and protein sequences of nogo genes and methods based thereon
IL198027A IL198027A (en) 1998-11-06 2009-04-06 Antibody of the NOGO gene, medicinal preparations containing the antibody and use of the antibody

Country Status (26)

Country Link
US (4) US7781188B1 (fr)
EP (3) EP2333064A1 (fr)
JP (2) JP2003531566A (fr)
KR (1) KR100728405B1 (fr)
CN (3) CN1721444A (fr)
AT (1) ATE435232T1 (fr)
AU (1) AU774367C (fr)
BR (1) BR9915137A (fr)
CA (1) CA2350395C (fr)
CY (1) CY1110679T1 (fr)
CZ (1) CZ304224B6 (fr)
DE (1) DE69941059D1 (fr)
DK (1) DK1124846T3 (fr)
ES (2) ES2329635T3 (fr)
HU (1) HUP0301829A3 (fr)
IL (3) IL142989A0 (fr)
MX (1) MXPA01004598A (fr)
NO (1) NO332460B1 (fr)
NZ (1) NZ511683A (fr)
PL (1) PL204293B1 (fr)
PT (1) PT1124846E (fr)
RU (3) RU2304585C2 (fr)
SK (1) SK287323B6 (fr)
TR (1) TR200700740T2 (fr)
WO (1) WO2000031235A2 (fr)
ZA (1) ZA200103714B (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020072493A1 (en) * 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
JP2002522016A (ja) * 1998-07-22 2002-07-23 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 神経内分泌特異的タンパク質に類似したタンパク質、およびそれをコードするcDNA
SK287323B6 (sk) 1998-11-06 2010-07-07 University Of Z�Rich Nogo proteín, jeho purifikovaný fragment, chimérny proteín a purifikovaná molekula s jeho obsahom, izolovaná nukleová kyselina, vektor s jej obsahom, rekombinantná bunka, spôsob produkcie rekombinantného proteínu a jeho použitie
US7186530B1 (en) 2000-04-07 2007-03-06 Chiron Corporation Protein associated with cell stress response
AU4216200A (en) * 1999-04-08 2000-10-23 Chiron Corporation Novel protein associated with cell stress response
HUP0203863A3 (en) * 2000-01-12 2008-03-28 Univ Yale Nogo receptor-mediated blockade of axonal growth
US7119165B2 (en) * 2000-01-12 2006-10-10 Yale University Nogo receptor-mediated blockade of axonal growth
US7049395B2 (en) 2000-05-02 2006-05-23 Yale University Anti-inflammatory compounds and uses thereof
ES2341608T3 (es) 2000-10-06 2010-06-23 Yale University Homologos del receptor de nogo.
GB0101312D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
GB0101313D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
AR040778A1 (es) 2002-08-06 2005-04-20 Glaxo Group Ltd Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina).
GB0228832D0 (en) 2002-12-10 2003-01-15 Novartis Ag Organic compound
US20060287501A1 (en) * 2002-10-31 2006-12-21 Pieris Proteolab Ag Soluble truncated polypeptides of the nogo-a protein
GB0306309D0 (en) 2003-03-19 2003-04-23 Glaxo Group Ltd Method of treatment
NZ548013A (en) * 2003-12-22 2009-04-30 Glaxo Group Ltd Immunoglobulins
PT1776136E (pt) 2004-06-24 2012-12-05 Biogen Idec Inc Tratamento de estados que envolvem desmielinização
KR100659820B1 (ko) 2004-11-17 2006-12-19 삼성에스디아이 주식회사 리튬 이온 이차 전지
US20090137484A1 (en) * 2004-12-01 2009-05-28 National University Of Singapore Neuronal Network-Interacting Peptide
EP1904091A4 (fr) 2005-07-07 2009-12-23 Univ Yale Compositions et procedes pour supprimer l'inhibition de la croissance axonale
SI1904104T1 (sl) 2005-07-08 2013-12-31 Biogen Idec Ma Inc. Protitelesa SP35 in njihova uporaba
US20070026463A1 (en) * 2005-07-28 2007-02-01 Wyeth Compositions and methods of mutant Nogo-66 domain proteins
JP2009515542A (ja) 2005-11-16 2009-04-16 ノバルティス アクチエンゲゼルシャフト 脊髄損傷における抗Nogo−A抗体処置のためのバイオマーカー
GB0525662D0 (en) 2005-12-16 2006-01-25 Glaxo Group Ltd Immunoglobulins
JP2009541211A (ja) * 2006-05-24 2009-11-26 ミエリン リペア ファウンデーション, インコーポレイテッド 血液脳関門の透過性
CN101015683B (zh) * 2007-01-18 2010-07-21 复旦大学 人rtn4b蛋白在制备创伤愈合药物中的应用
CA2704357C (fr) * 2007-11-02 2016-06-21 Novartis Ag Molecules ameliorees de liaison a nogo-a et utilisation pharmaceutique de celles-ci
WO2009065414A1 (fr) * 2007-11-22 2009-05-28 Symphogen A/S Procédé de caractérisation d'une protéine polyclonale recombinante
EP2315779A2 (fr) 2008-07-09 2011-05-04 Biogen Idec MA Inc. Compositions comprenant des anticorps anti-lingo ou leurs fragments
CN102439451B (zh) * 2009-06-02 2014-12-03 德克萨斯大学系统董事会 患神经退行性疾病的对象中抗体所识别的小分子的鉴定
US8828390B2 (en) 2010-07-09 2014-09-09 Universitat Zurich Uses of NOGO-A inhibitors and related methods
RU2478646C1 (ru) * 2011-11-28 2013-04-10 Федеральное государственное бюджетное учреждение науки Институт молекулярной биологии им.В.А.Энгельгардта Российской академии наук (ИМБ РАН) Способ получения высокоаффинных поликлональных антител
US9796780B2 (en) 2012-05-14 2017-10-24 Biogen Ma Inc. LINGO-2 antagonists for treatment of conditions involving motor neurons
EP3030171B1 (fr) * 2013-08-08 2017-11-01 Global Bio Therapeutics, Inc. Dispositif d'injection pour interventions peu invasives
KR101685109B1 (ko) * 2014-12-22 2016-12-09 경북대학교 산학협력단 근육 분화, 재생, 또는 질환 상태와 관련된 노고-에이의 용도
WO2016112270A1 (fr) 2015-01-08 2016-07-14 Biogen Ma Inc. Antagonistes de lingo-1 et leurs utilisations pour le traitement de troubles de démyélinisation
JP2018505161A (ja) * 2015-01-27 2018-02-22 ウニヴェルズィテート チューリッヒ 膠芽腫の治療のためのNogo−A S1PR経路のアゴニスト

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5A (en) * 1836-08-10 Thomas Blanchard Machine for mortising solid wooden shells of ships' tackle-blocks
US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
CA1173823A (fr) 1980-08-26 1984-09-04 Leonard M. Hjelmeland Detersif zwitterionique non denaturant pour la biochimie des membranes
EP0155433A1 (fr) 1984-03-23 1985-09-25 Adriano Fontana Facteur immunosuppresseur
CA1341401C (fr) 1984-03-23 2002-11-26 Adriano Fontana Facteur immunosuppresseur derive de cellules de glioblastome humain
EP0233838A3 (fr) 1986-02-04 1990-01-31 Incyte Pharmaceuticals, Inc. Facteur stimulant les neurites, et procédé de préparation
US5091313A (en) * 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
EP0413763B1 (fr) 1988-06-13 1996-11-06 American Biogenetic Sciences, Inc. Procede de production d'anticorps monoclonaux a l'aide d'un animal non porteur de germes
CA1341050C (fr) 1988-11-04 2000-07-11 Martin E. Schwab Facteurs de regulations de la croissance des axones
US5250414A (en) 1988-11-04 1993-10-05 Erziehungsdirektion Of The Canton Zurich Diagnostic methods using neurite growth regulatory factors
EP0396719B1 (fr) * 1988-11-04 1995-07-05 Erziehungsdirektion Of The Canton Zurich Facteurs de regulation de la croissance des neurites
AU2152092A (en) * 1991-06-24 1993-01-25 Erziehungsdirektion Of The Canton Zurich Neurite growth regulatory factors
US5858708A (en) * 1996-08-12 1999-01-12 Bandman; Olga Polynucleotides encoding two novel human neuroendocrine-specific proteins
CA2269755A1 (fr) * 1996-10-25 1998-04-30 Genetics Institute, Inc. Proteines secretees et polynucleotides codant ces proteines
WO1999033979A2 (fr) * 1997-12-30 1999-07-08 Chiron Corporation Proteines secretees par la moelle osseuse et polynucleotides
US6607879B1 (en) * 1998-02-09 2003-08-19 Incyte Corporation Compositions for the detection of blood cell and immunological response gene expression
US20020072493A1 (en) * 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
JP2002522016A (ja) 1998-07-22 2002-07-23 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 神経内分泌特異的タンパク質に類似したタンパク質、およびそれをコードするcDNA
WO2000011015A1 (fr) * 1998-08-24 2000-03-02 Alphagene, Inc. Proteines secretees et polynucleotides codant pour ces proteines
SK287323B6 (sk) 1998-11-06 2010-07-07 University Of Z�Rich Nogo proteín, jeho purifikovaný fragment, chimérny proteín a purifikovaná molekula s jeho obsahom, izolovaná nukleová kyselina, vektor s jej obsahom, rekombinantná bunka, spôsob produkcie rekombinantného proteínu a jeho použitie
WO2001036631A1 (fr) * 1999-11-15 2001-05-25 Smithkline Beecham P.L.C. Polynucleotides et polypeptides humains nogo-c et leurs utilisations
US20030134301A1 (en) * 2001-07-27 2003-07-17 Brooksbank Robert Alan Identification and use of molecules implicated in pain

Also Published As

Publication number Publication date
BR9915137A (pt) 2004-06-08
RU2009103533A (ru) 2010-11-10
ES2329635T3 (es) 2009-11-27
PL204293B1 (pl) 2009-12-31
KR20020003353A (ko) 2002-01-12
AU774367C (en) 2005-04-21
EP2093294A1 (fr) 2009-08-26
WO2000031235A3 (fr) 2000-11-09
TR200700740T2 (tr) 2007-04-24
RU2432364C2 (ru) 2011-10-27
SK287323B6 (sk) 2010-07-07
DE69941059D1 (de) 2009-08-13
EP2333064A1 (fr) 2011-06-15
NZ511683A (en) 2004-06-25
US20050260616A1 (en) 2005-11-24
ES2529196T3 (es) 2015-02-17
US7781188B1 (en) 2010-08-24
RU2358982C2 (ru) 2009-06-20
RU2304585C2 (ru) 2007-08-20
CN1354755B (zh) 2010-06-02
IL142989A (en) 2010-12-30
CN1354755A (zh) 2002-06-19
PT1124846E (pt) 2009-10-08
RU2001115705A (ru) 2004-03-10
CN101684155A (zh) 2010-03-31
AU774367B2 (en) 2004-06-24
NO20012223D0 (no) 2001-05-04
CA2350395C (fr) 2014-07-08
CN1721444A (zh) 2006-01-18
RU2004103555A (ru) 2005-07-20
EP1124846A2 (fr) 2001-08-22
DK1124846T3 (da) 2009-10-26
ATE435232T1 (de) 2009-07-15
EP2093294B1 (fr) 2014-10-29
CA2350395A1 (fr) 2000-06-02
US7425334B2 (en) 2008-09-16
SK6222001A3 (en) 2001-12-03
US20110086034A1 (en) 2011-04-14
US20090162367A1 (en) 2009-06-25
JP2003531566A (ja) 2003-10-28
NO332460B1 (no) 2012-09-24
EP1124846A4 (fr) 2002-06-12
KR100728405B1 (ko) 2007-06-13
CY1110679T1 (el) 2015-06-10
PL362990A1 (en) 2004-11-15
HUP0301829A2 (hu) 2003-08-28
AU1469200A (en) 2000-06-13
CZ304224B6 (cs) 2014-01-15
NO20012223L (no) 2001-07-02
JP2012213406A (ja) 2012-11-08
IL198027A (en) 2011-10-31
MXPA01004598A (es) 2002-04-24
CZ20011608A3 (cs) 2001-10-17
HK1038027A1 (en) 2002-03-01
ZA200103714B (en) 2004-06-25
WO2000031235A2 (fr) 2000-06-02
EP1124846B1 (fr) 2009-07-01
HUP0301829A3 (en) 2009-03-30

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