IL142989A0 - Nucleotide and protein sequences of nogo genes and methods based thereon - Google Patents

Nucleotide and protein sequences of nogo genes and methods based thereon

Info

Publication number
IL142989A0
IL142989A0 IL14298999A IL14298999A IL142989A0 IL 142989 A0 IL142989 A0 IL 142989A0 IL 14298999 A IL14298999 A IL 14298999A IL 14298999 A IL14298999 A IL 14298999A IL 142989 A0 IL142989 A0 IL 142989A0
Authority
IL
Israel
Prior art keywords
nucleotide
protein sequences
methods based
nogo
nogo genes
Prior art date
Application number
IL14298999A
Other languages
English (en)
Inventor
Martin E Schwab
Maio S Chen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22316666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL142989(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of IL142989A0 publication Critical patent/IL142989A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
IL14298999A 1998-11-06 1999-11-05 Nucleotide and protein sequences of nogo genes and methods based thereon IL142989A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10744698P 1998-11-06 1998-11-06
PCT/US1999/026160 WO2000031235A2 (fr) 1998-11-06 1999-11-05 Sequences nucleotidiques et proteiques de gene nogo et procedes reposant sur ces sequences

Publications (1)

Publication Number Publication Date
IL142989A0 true IL142989A0 (en) 2002-04-21

Family

ID=22316666

Family Applications (3)

Application Number Title Priority Date Filing Date
IL14298999A IL142989A0 (en) 1998-11-06 1999-11-05 Nucleotide and protein sequences of nogo genes and methods based thereon
IL142989A IL142989A (en) 1998-11-06 2001-05-06 Nucleotide and protein sequences of nogo genes and methods based thereon
IL198027A IL198027A (en) 1998-11-06 2009-04-06 Antibody of the NOGO gene, medicinal preparations containing the antibody and use of the antibody

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL142989A IL142989A (en) 1998-11-06 2001-05-06 Nucleotide and protein sequences of nogo genes and methods based thereon
IL198027A IL198027A (en) 1998-11-06 2009-04-06 Antibody of the NOGO gene, medicinal preparations containing the antibody and use of the antibody

Country Status (26)

Country Link
US (4) US7781188B1 (fr)
EP (3) EP1124846B1 (fr)
JP (2) JP2003531566A (fr)
KR (1) KR100728405B1 (fr)
CN (3) CN101684155A (fr)
AT (1) ATE435232T1 (fr)
AU (1) AU774367C (fr)
BR (1) BR9915137A (fr)
CA (1) CA2350395C (fr)
CY (1) CY1110679T1 (fr)
CZ (1) CZ304224B6 (fr)
DE (1) DE69941059D1 (fr)
DK (1) DK1124846T3 (fr)
ES (2) ES2529196T3 (fr)
HU (1) HUP0301829A3 (fr)
IL (3) IL142989A0 (fr)
MX (1) MXPA01004598A (fr)
NO (1) NO332460B1 (fr)
NZ (1) NZ511683A (fr)
PL (1) PL204293B1 (fr)
PT (1) PT1124846E (fr)
RU (3) RU2304585C2 (fr)
SK (1) SK287323B6 (fr)
TR (1) TR200700740T2 (fr)
WO (1) WO2000031235A2 (fr)
ZA (1) ZA200103714B (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020072493A1 (en) * 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
DE69942803D1 (de) * 1998-07-22 2010-11-11 Smithkline Beecham Ltd Rotein änhelt, und dafür kodierende cdns
WO2000031235A2 (fr) 1998-11-06 2000-06-02 Schwab Martin E Sequences nucleotidiques et proteiques de gene nogo et procedes reposant sur ces sequences
AU4216200A (en) * 1999-04-08 2000-10-23 Chiron Corporation Novel protein associated with cell stress response
US7186530B1 (en) 2000-04-07 2007-03-06 Chiron Corporation Protein associated with cell stress response
US7119165B2 (en) * 2000-01-12 2006-10-10 Yale University Nogo receptor-mediated blockade of axonal growth
HUP0203863A3 (en) * 2000-01-12 2008-03-28 Univ Yale Nogo receptor-mediated blockade of axonal growth
US7049395B2 (en) 2000-05-02 2006-05-23 Yale University Anti-inflammatory compounds and uses thereof
EP1325130B1 (fr) 2000-10-06 2010-02-24 Yale University Homologues du recepteur de nogo
GB0101313D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
GB0101312D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
TWI323265B (en) 2002-08-06 2010-04-11 Glaxo Group Ltd Antibodies
GB0228832D0 (en) 2002-12-10 2003-01-15 Novartis Ag Organic compound
WO2004039836A1 (fr) * 2002-10-31 2004-05-13 Pieris Proteolab Ag Polypeptides tronques solubles de la proteine nogo-a
GB0306309D0 (en) 2003-03-19 2003-04-23 Glaxo Group Ltd Method of treatment
US7988964B2 (en) * 2003-12-22 2011-08-02 Glaxo Group Limited NOGO-a neutralising immunoglobulin for treatment of neurological diseases
KR101239542B1 (ko) 2004-06-24 2013-03-07 바이오겐 아이덱 엠에이 인코포레이티드 탈수초화를 수반하는 병의 치료
KR100659820B1 (ko) 2004-11-17 2006-12-19 삼성에스디아이 주식회사 리튬 이온 이차 전지
WO2006059959A1 (fr) * 2004-12-01 2006-06-08 National University Of Singapore Fragments proteiniques nogo-a utiles comme peptides ayant une interaction avec le reseau neuronal
WO2007008732A2 (fr) 2005-07-07 2007-01-18 Yale University Compositions et procedes pour supprimer l'inhibition de la croissance axonale
CA2902070A1 (fr) 2005-07-08 2007-01-18 Biogen Idec Ma Inc. Anticorps anti-sp35 et leurs utilisations
WO2007014382A1 (fr) * 2005-07-28 2007-02-01 Wyeth Compositions de proteines possedant le domaine nogo 66 mutant et methodes associees
RU2008123384A (ru) 2005-11-16 2009-12-27 Новартис АГ (CH) БИОМАРКЕРЫ ДЛЯ ЛЕЧЕНИЯ АНТИТЕЛОМ к Nogo-A ПРИ ПОВРЕЖДЕНИЯХ СПИННОГО МОЗГА
GB0525662D0 (en) 2005-12-16 2006-01-25 Glaxo Group Ltd Immunoglobulins
WO2007137303A2 (fr) * 2006-05-24 2007-11-29 Myelin Repair Foundation, Inc. Perméabilité de la barrière hémato-encéphalique
CN101015683B (zh) * 2007-01-18 2010-07-21 复旦大学 人rtn4b蛋白在制备创伤愈合药物中的应用
AU2008317724B2 (en) * 2007-11-02 2011-06-02 Novartis Ag Improved Nogo-A binding molecules and pharmaceutical use thereof
RU2476886C2 (ru) * 2007-11-22 2013-02-27 Симфоген А/С Способ характеризации рекомбинантного поликлонального белка
JP2011527572A (ja) 2008-07-09 2011-11-04 バイオジェン・アイデック・エムエイ・インコーポレイテッド Ｌｉｎｇｏ抗体または断片を含む組成物
CA2764153C (fr) * 2009-06-02 2021-07-27 The Board Of Regents Of The University Of Texas System Identification de petites molecules reconnues par des anticorps chez des sujets atteints de maladies neurodegeneratives
US8828390B2 (en) 2010-07-09 2014-09-09 Universitat Zurich Uses of NOGO-A inhibitors and related methods
RU2478646C1 (ru) * 2011-11-28 2013-04-10 Федеральное государственное бюджетное учреждение науки Институт молекулярной биологии им.В.А.Энгельгардта Российской академии наук (ИМБ РАН) Способ получения высокоаффинных поликлональных антител
MX381731B (es) 2012-05-14 2025-03-13 Biogen Ma Inc Antagonistas de proteina que interactua con el receptor nogo 2 que contiene repeticion rica en leucina y dominio de inmunoglobulina (lingo-2) para el tratamiento de afecciones que involucran neuronas motoras.
ES2647789T3 (es) * 2013-08-08 2017-12-26 Global Bio Therapeutics, Inc. Dispositivo de inyección para procedimientos mínimamente invasivos
KR101685109B1 (ko) * 2014-12-22 2016-12-09 경북대학교 산학협력단 근육 분화, 재생, 또는 질환 상태와 관련된 노고-에이의 용도
JP2018504400A (ja) 2015-01-08 2018-02-15 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． Ｌｉｎｇｏ‐１拮抗薬及び脱髄障害の治療のための使用
EP3250220B1 (fr) * 2015-01-27 2020-03-11 Universität Zürich Agonistes de la voie s1pr nogo-a pour le traitement du glioblastome

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5A (en) * 1836-08-10 Thomas Blanchard Machine for mortising solid wooden shells of ships' tackle-blocks
US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
CA1173823A (fr) 1980-08-26 1984-09-04 Leonard M. Hjelmeland Detersif zwitterionique non denaturant pour la biochimie des membranes
EP0155433A1 (fr) 1984-03-23 1985-09-25 Adriano Fontana Facteur immunosuppresseur
CA1341401C (fr) 1984-03-23 2002-11-26 Adriano Fontana Facteur immunosuppresseur derive de cellules de glioblastome humain
EP0233838A3 (fr) 1986-02-04 1990-01-31 Incyte Pharmaceuticals, Inc. Facteur stimulant les neurites, et procédé de préparation
US5091313A (en) * 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
ATE145007T1 (de) 1988-06-13 1996-11-15 American Biogenetic Sciences Verfahren zur herstellung monoklonaler antikörper mit hilfe eines keimfreien tieres
DE68923362T2 (de) 1988-11-04 1996-03-28 Zuerich Erziehungsdirektion Wachstumsregelfaktoren für neuriten.
US5250414A (en) 1988-11-04 1993-10-05 Erziehungsdirektion Of The Canton Zurich Diagnostic methods using neurite growth regulatory factors
CA1341050C (fr) 1988-11-04 2000-07-11 Martin E. Schwab Facteurs de regulations de la croissance des axones
WO1993000427A2 (fr) 1991-06-24 1993-01-07 Erziehungsdirektion Of The Canton Zurich Facteurs regulateurs de la croissance des neurites
US5858708A (en) * 1996-08-12 1999-01-12 Bandman; Olga Polynucleotides encoding two novel human neuroendocrine-specific proteins
CA2269755A1 (fr) * 1996-10-25 1998-04-30 Genetics Institute, Inc. Proteines secretees et polynucleotides codant ces proteines
AU1929599A (en) * 1997-12-30 1999-07-19 Chiron Corporation Bone marrow secreted proteins and polynucleotides
US6607879B1 (en) * 1998-02-09 2003-08-19 Incyte Corporation Compositions for the detection of blood cell and immunological response gene expression
US20020072493A1 (en) * 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
DE69942803D1 (de) 1998-07-22 2010-11-11 Smithkline Beecham Ltd Rotein änhelt, und dafür kodierende cdns
WO2000011015A1 (fr) * 1998-08-24 2000-03-02 Alphagene, Inc. Proteines secretees et polynucleotides codant pour ces proteines
WO2000031235A2 (fr) 1998-11-06 2000-06-02 Schwab Martin E Sequences nucleotidiques et proteiques de gene nogo et procedes reposant sur ces sequences
EP1147192A1 (fr) * 1999-11-15 2001-10-24 Smithkline Beecham Plc Polynucleotides et polypeptides humains nogo-c et leurs utilisations
US20030134301A1 (en) * 2001-07-27 2003-07-17 Brooksbank Robert Alan Identification and use of molecules implicated in pain

Also Published As

Publication number Publication date
JP2003531566A (ja) 2003-10-28
RU2009103533A (ru) 2010-11-10
DK1124846T3 (da) 2009-10-26
WO2000031235A2 (fr) 2000-06-02
JP2012213406A (ja) 2012-11-08
CN1354755A (zh) 2002-06-19
CA2350395A1 (fr) 2000-06-02
CN101684155A (zh) 2010-03-31
HUP0301829A2 (hu) 2003-08-28
KR100728405B1 (ko) 2007-06-13
CA2350395C (fr) 2014-07-08
RU2304585C2 (ru) 2007-08-20
AU1469200A (en) 2000-06-13
CZ304224B6 (cs) 2014-01-15
US20110086034A1 (en) 2011-04-14
NO332460B1 (no) 2012-09-24
AU774367B2 (en) 2004-06-24
PL362990A1 (en) 2004-11-15
IL198027A (en) 2011-10-31
NO20012223D0 (no) 2001-05-04
US7781188B1 (en) 2010-08-24
WO2000031235A3 (fr) 2000-11-09
CN1354755B (zh) 2010-06-02
KR20020003353A (ko) 2002-01-12
US20050260616A1 (en) 2005-11-24
RU2004103555A (ru) 2005-07-20
SK6222001A3 (en) 2001-12-03
EP2093294A1 (fr) 2009-08-26
EP1124846B1 (fr) 2009-07-01
ATE435232T1 (de) 2009-07-15
EP1124846A2 (fr) 2001-08-22
SK287323B6 (sk) 2010-07-07
CY1110679T1 (el) 2015-06-10
RU2001115705A (ru) 2004-03-10
RU2432364C2 (ru) 2011-10-27
CN1721444A (zh) 2006-01-18
ES2529196T3 (es) 2015-02-17
AU774367C (en) 2005-04-21
IL142989A (en) 2010-12-30
DE69941059D1 (de) 2009-08-13
EP2333064A1 (fr) 2011-06-15
BR9915137A (pt) 2004-06-08
RU2358982C2 (ru) 2009-06-20
EP1124846A4 (fr) 2002-06-12
MXPA01004598A (es) 2002-04-24
ES2329635T3 (es) 2009-11-27
HK1038027A1 (en) 2002-03-01
NZ511683A (en) 2004-06-25
ZA200103714B (en) 2004-06-25
HUP0301829A3 (en) 2009-03-30
PL204293B1 (pl) 2009-12-31
EP2093294B1 (fr) 2014-10-29
CZ20011608A3 (cs) 2001-10-17
US7425334B2 (en) 2008-09-16
TR200700740T2 (tr) 2007-04-24
PT1124846E (pt) 2009-10-08
US20090162367A1 (en) 2009-06-25
NO20012223L (no) 2001-07-02

Similar Documents

Publication Publication Date Title
IL142989A (en) Nucleotide and protein sequences of nogo genes and methods based thereon
WO2000003685A3 (fr) Homologues de nitrilase
FR2637612B1 (fr) Sequences de nucleotides codant pour une proteine a activite ureasique
WO2001032910A3 (fr) 27 proteines humaines secretees
WO2001036432A3 (fr) 18 proteines secretees humaines
WO2001034768A3 (fr) 15 proteines secretees humaines
WO2001012776A3 (fr) 18 proteines secretees humaines
WO2000077026A8 (fr) 49 proteines secretees humaines
WO2000063230A3 (fr) 49 proteines secretees humaines
WO2001062891A3 (fr) 207 proteines humaines secretees
ATE310091T1 (de) Carboxypeptidasen aus aspergillus oryzae und diese kodierende nukleinsäuren
WO2001012775A8 (fr) 25 proteines secretees humaines
WO2000058339A3 (fr) 50 proteines humaines secretees
WO1999063094A3 (fr) Sequences nucleotidiques et proteiques gpr1 et methodes y relatives
WO2000043495A3 (fr) Proteines humaines secretees (33)
WO2000061624A8 (fr) 48 proteines secretees humaines
WO2003052377A9 (fr) 41 proteines secretees humaines
DE69730967D1 (en) Human dnase ii
WO2000061596A8 (fr) 50 proteines humaines secretees
WO2003040320A3 (fr) Modulation par composes antisens de l'expression de la proteine 2 mediatrice de reaction de collapsine humaine (crmp)
WO2001059113A3 (fr) Nouvelles proteines et acides nucleiques codant ces dernieres
WO2002099066A3 (fr) 20 proteines humaines secretees
WO2001034769A3 (fr) 24 proteines humaines secretees
HK1043155A1 (zh) 噬菌體t4基因35的基因及蛋白質排列
WO2002057420A3 (fr) 50 proteines secretees humaines