IL143123A0 - Methods for the preparation of nucleic acid and polypeptide libraries and uses thereof - Google Patents

Methods for the preparation of nucleic acid and polypeptide libraries and uses thereof

Info

Publication number
IL143123A0
IL143123A0 IL14312399A IL14312399A IL143123A0 IL 143123 A0 IL143123 A0 IL 143123A0 IL 14312399 A IL14312399 A IL 14312399A IL 14312399 A IL14312399 A IL 14312399A IL 143123 A0 IL143123 A0 IL 143123A0
Authority
IL
Israel
Prior art keywords
nucleic acid
recombination
methods
libraries
replication
Prior art date
Application number
IL14312399A
Other languages
English (en)
Original Assignee
S I S S A Scuola Internaz Supe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by S I S S A Scuola Internaz Supe filed Critical S I S S A Scuola Internaz Supe
Publication of IL143123A0 publication Critical patent/IL143123A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Ceramic Products (AREA)
  • Medicines Containing Plant Substances (AREA)
IL14312399A 1998-11-19 1999-11-18 Methods for the preparation of nucleic acid and polypeptide libraries and uses thereof IL143123A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI002509A IT1303776B1 (it) 1998-11-19 1998-11-19 Processo per la preparazione di genoteche, di polipeptidi utilizzandodette genoteche e i polipepti ottenuti.
PCT/EP1999/008856 WO2000031246A2 (en) 1998-11-19 1999-11-18 Methods for the preparation by in vivo recombination of nucleic acid and polypeptide libraries and uses thereof

Publications (1)

Publication Number Publication Date
IL143123A0 true IL143123A0 (en) 2002-04-21

Family

ID=11381090

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14312399A IL143123A0 (en) 1998-11-19 1999-11-18 Methods for the preparation of nucleic acid and polypeptide libraries and uses thereof
IL143123A IL143123A (en) 1998-11-19 2001-05-14 Methods for the preparation by in vivo recombination of nucleic acid and polypeptide libraries and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL143123A IL143123A (en) 1998-11-19 2001-05-14 Methods for the preparation by in vivo recombination of nucleic acid and polypeptide libraries and uses thereof

Country Status (9)

Country Link
EP (1) EP1131421B1 (de)
AT (1) ATE333502T1 (de)
AU (1) AU3790300A (de)
CA (1) CA2350779A1 (de)
DE (1) DE69932446T2 (de)
ES (1) ES2268907T3 (de)
IL (2) IL143123A0 (de)
IT (1) IT1303776B1 (de)
WO (1) WO2000031246A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6780620B1 (en) 1998-12-23 2004-08-24 Bristol-Myers Squibb Company Microbial transformation method for the preparation of an epothilone
US6686154B2 (en) * 2000-06-05 2004-02-03 Zyomyx, Inc. Screening of phage displayed peptides without clearing of the cell culture
EP1457559B1 (de) * 2001-11-22 2008-01-16 Keio University Künstliche antikörperbibliothek mit super-repertoire
CN105153307A (zh) 2010-05-04 2015-12-16 梅里麦克制药股份有限公司 抗表皮生长因子受体(egfr)的抗体及其用途
US8691231B2 (en) 2011-06-03 2014-04-08 Merrimack Pharmaceuticals, Inc. Methods of treatment of tumors expressing predominantly high affinity EGFR ligands or tumors expressing predominantly low affinity EGFR ligands with monoclonal and oligoclonal anti-EGFR antibodies
WO2013173582A1 (en) 2012-05-17 2013-11-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Hepatitis c virus neutralizing antibody
US9751931B2 (en) 2012-10-26 2017-09-05 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Hepatitis C virus neutralizing antibodies and methods
WO2018129451A2 (en) 2017-01-09 2018-07-12 Merrimack Pharmaceuticals, Inc. Anti-fgfr antibodies and methods of use
TWI788340B (zh) 2017-04-07 2023-01-01 美商必治妥美雅史谷比公司 抗icos促效劑抗體及其用途
EP3694552A1 (de) 2017-10-10 2020-08-19 Tilos Therapeutics, Inc. Anti-lap-antikörper und verwendungen davon
CN113056487A (zh) 2018-09-18 2021-06-29 梅里麦克制药股份有限公司 抗tnfr2抗体及其用途
EP3863722A2 (de) 2018-10-10 2021-08-18 Tilos Theapeutics, Inc. Anti-lap-antikörper und verwendungen davon
EP3870604B1 (de) * 2018-10-26 2022-11-23 F. Hoffmann-La Roche AG Screeningverfahren für multispezifische antiköper mittels rekombinase-vermitteltem kassettenaustausch
CN113874083A (zh) 2019-03-01 2021-12-31 梅里麦克制药股份有限公司 抗-tnfr2抗体及其用途
CN113661173B (zh) 2019-03-29 2024-10-01 豪夫迈·罗氏有限公司 通过以限定的组织形式靶向整合多个表达盒来产生表达FcRn的细胞的方法
WO2021190631A1 (zh) * 2020-03-27 2021-09-30 泷搌（上海）生物科技有限公司 在哺乳动物细胞表面展示双特异性抗体的方法及载体
EP4132971A1 (de) 2020-04-09 2023-02-15 Merck Sharp & Dohme LLC Affinitätsgereifte anti-lap-antikörper und verwendungen davon
CN117430696A (zh) * 2022-07-22 2024-01-23 北京智仁美博生物科技有限公司 用于表达Fab片段库的重组系统

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117679A (en) * 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5728557A (en) * 1995-06-01 1998-03-17 Merck & Co., Inc. Method of making herpes simplex type 1 mutants and mutants so produced
WO1998028416A1 (en) * 1996-12-20 1998-07-02 Novo Nordisk A/S In vivo recombination

Also Published As

Publication number Publication date
DE69932446D1 (de) 2006-08-31
ATE333502T1 (de) 2006-08-15
EP1131421A2 (de) 2001-09-12
IT1303776B1 (it) 2001-02-23
ES2268907T3 (es) 2007-03-16
EP1131421B1 (de) 2006-07-19
DE69932446T2 (de) 2007-01-04
WO2000031246A2 (en) 2000-06-02
AU3790300A (en) 2000-06-13
WO2000031246A3 (en) 2000-08-17
ITMI982509A1 (it) 2000-05-19
CA2350779A1 (en) 2000-06-02
IL143123A (en) 2009-11-18

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