IL143830A0 - BENZISOXAZOLES AND PHENONES AS α2-ANTAGONISTS - Google Patents

BENZISOXAZOLES AND PHENONES AS α2-ANTAGONISTS

Info

Publication number: IL143830A0
Authority: IL; Israel
Prior art keywords: benzisoxazoles; phenones; antagonists
Prior art date: 1998-12-21

Application number

IL14383099A

Other languages

English (en)

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-21

Filing date

1999-12-14

Publication date

2002-04-21

1999-12-14 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2002-04-21 Publication of IL143830A0 publication Critical patent/IL143830A0/xx

Links

239000000670 adrenergic alpha-2 receptor antagonist Substances 0.000 title 1
150000008316 benzisoxazoles Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Gynecology & Obstetrics (AREA)
Hematology (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Ophthalmology & Optometry (AREA)
Reproductive Health (AREA)
Emergency Medicine (AREA)
Pain & Pain Management (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Plural Heterocyclic Compounds (AREA)

IL14383099A 1998-12-21 1999-12-14 BENZISOXAZOLES AND PHENONES AS α2-ANTAGONISTS IL143830A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98204358		1998-12-21
PCT/EP1999/010054 WO2000037466A1 (en)	1998-12-21	1999-12-14	BENZISOXAZOLES AND PHENONES AS α2-ANTAGONISTS

Publications (1)

Publication Number	Publication Date
IL143830A0 true IL143830A0 (en)	2002-04-21

Family

ID=8234508

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL14383099A IL143830A0 (en)	1998-12-21	1999-12-14	BENZISOXAZOLES AND PHENONES AS α2-ANTAGONISTS
IL143830A IL143830A (en)	1998-12-21	2001-06-19	History 2 - Benzisoxazolylpentyl and 2 - Benzoylpentylpyridoindole a2 - adrenoceptor antagonists and their analogues, their preparation and pharmaceutical preparations containing them

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL143830A IL143830A (en)	1998-12-21	2001-06-19	History 2 - Benzisoxazolylpentyl and 2 - Benzoylpentylpyridoindole a2 - adrenoceptor antagonists and their analogues, their preparation and pharmaceutical preparations containing them

Country Status (30)

Country	Link
US (1)	US6576640B1 (de)
EP (1)	EP1140934B1 (de)
JP (1)	JP4717216B2 (de)
KR (2)	KR100657540B1 (de)
CN (1)	CN1154646C (de)
AR (1)	AR021924A1 (de)
AT (1)	ATE251622T1 (de)
AU (1)	AU765751B2 (de)
BG (1)	BG65162B1 (de)
BR (1)	BR9916427A (de)
CA (1)	CA2355716C (de)
CZ (1)	CZ294532B6 (de)
DE (1)	DE69911995T2 (de)
EA (1)	EA003606B1 (de)
EE (1)	EE200100329A (de)
ES (1)	ES2209553T3 (de)
HK (1)	HK1045686B (de)
HR (1)	HRP20010444A2 (de)
HU (1)	HUP0104812A3 (de)
ID (1)	ID28967A (de)
IL (2)	IL143830A0 (de)
NO (1)	NO317892B1 (de)
NZ (1)	NZ511411A (de)
PL (1)	PL196958B1 (de)
SK (1)	SK285560B6 (de)
TR (1)	TR200101813T2 (de)
TW (1)	TWI229673B (de)
UA (1)	UA71938C2 (de)
WO (1)	WO2000037466A1 (de)
ZA (1)	ZA200105067B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MXPA04000036A (es) *	2001-07-05	2004-05-21	Upjohn Co	Benzofuranos sustituidos con (hetero) arilo como ligandos 5-ht.
US20050203100A1 (en) *	2002-04-03	2005-09-15	Jukka Sallinen	Use of an alfa2-adrenoreceptor antagonist for cns-related diseases
JP4816453B2 (ja)	2004-04-12	2011-11-16	大正製薬株式会社	環状アミン化合物
MX2008000811A (es) *	2005-07-28	2008-03-18	Squibb Bristol Myers Co	Tetrahidro-1h-pitido[4,3-b]indoles substituidos como agonistas y antagonistas del receptor de serotonina.
CN117327065B (zh) *	2022-06-23	2026-06-19	北京大学	作为多巴胺d2/3受体调节剂的咔唑类衍生物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3419568A (en) *	1966-12-07	1968-12-31	Abbott Lab	Derivatives of 1,2,3,4-tetrahydro-5h-pyrido[4,3b]indoles
US3382250A (en) *	1966-12-07	1968-05-07	Abbott Lab	Aroylalkyl derivatives of 1, 2, 3, 4-tetrahydro-5h-pyrido[4, 3b]indoles
US3718657A (en) *	1970-12-03	1973-02-27	Abbott Lab	Certain-2-substituted-1,2,3,4-tetrahydro-beta or gamma carbolines
JPS4729395U (de) *	1971-04-26	1972-12-04
AR206812A1 (es) *	1974-04-01	1976-08-23	Pfizer	Compuestos intermediarios de azaciclo(3,4-a)indoles 4- y 5-fenil substituidos desprovistos de actividad terapeutica
US4001263A (en) *	1974-04-01	1977-01-04	Pfizer Inc.	5-Aryl-1,2,3,4-tetrahydro-γ-carbolines
US4224329A (en) *	1979-01-23	1980-09-23	Pfizer Inc.	2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
FR2570701B1 (fr) *	1984-09-27	1987-05-22	Synthelabo	Derives de furo(3,2-c)pyridines, leur preparation et leur application en therapeutique
DE3522959A1 (de) *	1985-06-27	1987-01-08	Merck Patent Gmbh	Indolderivate
EP0339959A3 (de) *	1988-04-27	1991-03-20	Glaxo Group Limited	Laktam-Derivate
WO1994008040A1 (en) *	1992-09-25	1994-04-14	Synaptic Pharmaceutical Corporation	Dna encoding human alpha 1 adrenergic receptors and uses thereof
US5403847A (en)	1992-11-13	1995-04-04	Synaptic Pharmaceutical Corporation	Use of α1C specific compounds to treat benign prostatic hyperlasia
US5508306A (en) *	1992-11-13	1996-04-16	Synaptic Pharmaceutical Corporation	Aromatic amine derivatives
UA52681C2 (uk) *	1997-04-08	2003-01-15	Янссен Фармацевтика Н.В.	Похідні 1,2,3,4-тетрагідро-бензофуро[3,2,-c]піридину, спосіб їх одержання та фармацевтична композиція на їх основі

1999
- 1999-12-14 JP JP2000589537A patent/JP4717216B2/ja not_active Expired - Fee Related
- 1999-12-14 BR BR9916427-2A patent/BR9916427A/pt not_active Application Discontinuation
- 1999-12-14 CN CNB998147095A patent/CN1154646C/zh not_active Expired - Fee Related
- 1999-12-14 CZ CZ20012120A patent/CZ294532B6/cs not_active IP Right Cessation
- 1999-12-14 ID IDW00200101335A patent/ID28967A/id unknown
- 1999-12-14 AT AT99967955T patent/ATE251622T1/de not_active IP Right Cessation
- 1999-12-14 ES ES99967955T patent/ES2209553T3/es not_active Expired - Lifetime
- 1999-12-14 EE EEP200100329A patent/EE200100329A/xx unknown
- 1999-12-14 NZ NZ511411A patent/NZ511411A/xx unknown
- 1999-12-14 IL IL14383099A patent/IL143830A0/xx active IP Right Grant
- 1999-12-14 UA UA2001064352A patent/UA71938C2/uk unknown
- 1999-12-14 KR KR1020017004946A patent/KR100657540B1/ko not_active Expired - Fee Related
- 1999-12-14 SK SK858-2001A patent/SK285560B6/sk unknown
- 1999-12-14 CA CA2355716A patent/CA2355716C/en not_active Expired - Fee Related
- 1999-12-14 EP EP99967955A patent/EP1140934B1/de not_active Expired - Lifetime
- 1999-12-14 TR TR2001/01813T patent/TR200101813T2/xx unknown
- 1999-12-14 HU HU0104812A patent/HUP0104812A3/hu unknown
- 1999-12-14 HR HR20010444A patent/HRP20010444A2/hr not_active Application Discontinuation
- 1999-12-14 EA EA200100709A patent/EA003606B1/ru not_active IP Right Cessation
- 1999-12-14 DE DE69911995T patent/DE69911995T2/de not_active Expired - Lifetime
- 1999-12-14 KR KR1020067015507A patent/KR20060093139A/ko not_active Ceased
- 1999-12-14 AU AU24327/00A patent/AU765751B2/en not_active Ceased
- 1999-12-14 PL PL348421A patent/PL196958B1/pl unknown
- 1999-12-14 WO PCT/EP1999/010054 patent/WO2000037466A1/en not_active Ceased
- 1999-12-14 HK HK02105098.8A patent/HK1045686B/zh not_active IP Right Cessation
- 1999-12-14 US US09/868,756 patent/US6576640B1/en not_active Expired - Lifetime
- 1999-12-16 TW TW088122067A patent/TWI229673B/zh not_active IP Right Cessation
- 1999-12-20 AR ARP990106577A patent/AR021924A1/es active IP Right Grant
2001
- 2001-05-18 BG BG105521A patent/BG65162B1/bg unknown
- 2001-06-06 NO NO20012783A patent/NO317892B1/no unknown
- 2001-06-19 IL IL143830A patent/IL143830A/en not_active IP Right Cessation
- 2001-06-20 ZA ZA200105067A patent/ZA200105067B/en unknown

Also Published As

Publication number	Publication date
JP2002533341A (ja)	2002-10-08
EA003606B1 (ru)	2003-06-26
IL143830A (en)	2007-07-24
DE69911995D1 (de)	2003-11-13
BR9916427A (pt)	2001-09-04
AU765751B2 (en)	2003-09-25
NO317892B1 (no)	2004-12-27
EE200100329A (et)	2002-08-15
SK8582001A3 (en)	2001-12-03
KR20060093139A (ko)	2006-08-23
KR20010075650A (ko)	2001-08-09
HUP0104812A2 (hu)	2002-04-29
BG105521A (en)	2001-12-29
UA71938C2 (en)	2005-01-17
BG65162B1 (bg)	2007-04-30
WO2000037466A1 (en)	2000-06-29
KR100657540B1 (ko)	2006-12-14
TR200101813T2 (tr)	2001-12-21
HK1045686B (zh)	2005-04-01
HK1045686A1 (en)	2002-12-06
NO20012783L (no)	2001-06-06
CN1331692A (zh)	2002-01-16
AU2432700A (en)	2000-07-12
SK285560B6 (sk)	2007-03-01
TWI229673B (en)	2005-03-21
NO20012783D0 (no)	2001-06-06
NZ511411A (en)	2002-12-20
EA200100709A1 (ru)	2001-12-24
DE69911995T2 (de)	2004-09-02
PL196958B1 (pl)	2008-02-29
ZA200105067B (en)	2002-06-20
JP4717216B2 (ja)	2011-07-06
CZ294532B6 (cs)	2005-01-12
CA2355716A1 (en)	2000-06-29
HRP20010444A2 (en)	2002-06-30
PL348421A1 (en)	2002-05-20
CZ20012120A3 (cs)	2001-10-17
CN1154646C (zh)	2004-06-23
EP1140934A1 (de)	2001-10-10
ES2209553T3 (es)	2004-06-16
US6576640B1 (en)	2003-06-10
CA2355716C (en)	2010-05-18
EP1140934B1 (de)	2003-10-08
AR021924A1 (es)	2002-09-04
ID28967A (id)	2001-07-19
ATE251622T1 (de)	2003-10-15
HUP0104812A3 (en)	2003-12-29

Legal Events

Date	Code	Title	Description
2008-01-06	FF	Patent granted
2008-01-06	KB	Patent renewed

Publication	Publication Date	Title
DE69924108D1 (en)	2005-04-14	Offshore-bohrsystem
EP1102535A4 (de)	2004-09-29	Verbindungen und verfahren
GB2336711B (en)	2002-01-09	Cables
DE69943409D1 (en)	2011-06-16	Fmcw-radar
AU2349399A (en)	1999-08-16	R-lansoprazole compositions and methods
GB9801877D0 (en)	1998-03-25	Aerators
HU9900892D0 (en)	1999-06-28	Enclosed multiple-biofilter
PL348421A1 (en)	2002-05-20	Benzisoxazoles and phenones as α2
HU9900891D0 (en)	1999-06-28	Putrefy set
DE69912430D1 (en)	2003-12-04	Hydroformylierungsreaktionen
GB2336996B (en)	2002-11-06	Multi-desk
AU2331699A (en)	1999-08-09	Self-inducting aerator
EP1098583A4 (de)	2002-11-20	Badewannensitz
GB2332917B (en)	2002-03-13	Building insert members
DE59911094D1 (en)	2004-12-23	Tryptase-inhibitoren
AUPP642798A0 (en)	1998-10-29	Improvements in water distribution
GB9807430D0 (en)	1998-06-03	Rapid Floar
GB9801431D0 (en)	1998-03-18	Curvers
EG21492A (en)	2001-11-28	Outo-calcimeter
GB9803826D0 (en)	1998-04-22	Easy rockeries
CZ80198A3 (cs)	1999-11-17	Kabel
GB9810642D0 (en)	1998-07-15	Plastoc gland adaptor
CA83795S (en)	1998-05-08	Faucet
CA83796S (en)	1998-05-08	Faucet
CA84194S (en)	1998-06-26	Faucet