IL144374A0 - Method of identifying cytosine methylation patterns in genomic dna samples - Google Patents

Method of identifying cytosine methylation patterns in genomic dna samples

Info

Publication number
IL144374A0
IL144374A0 IL14437400A IL14437400A IL144374A0 IL 144374 A0 IL144374 A0 IL 144374A0 IL 14437400 A IL14437400 A IL 14437400A IL 14437400 A IL14437400 A IL 14437400A IL 144374 A0 IL144374 A0 IL 144374A0
Authority
IL
Israel
Prior art keywords
dna sample
probes
genomic dna
hybridized
methylation patterns
Prior art date
Application number
IL14437400A
Other languages
English (en)
Original Assignee
Epigenomics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epigenomics Ag filed Critical Epigenomics Ag
Publication of IL144374A0 publication Critical patent/IL144374A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
IL14437400A 1999-01-29 2000-01-27 Method of identifying cytosine methylation patterns in genomic dna samples IL144374A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19905082A DE19905082C1 (de) 1999-01-29 1999-01-29 Verfahren zur Identifikation von Cytosin-Methylierungsmustern in genomischen DNA-Proben
PCT/DE2000/000288 WO2000044934A2 (fr) 1999-01-29 2000-01-27 Procede d'identification de modeles de methylation de cytosine dans des echantillons d'adn genomiques

Publications (1)

Publication Number Publication Date
IL144374A0 true IL144374A0 (en) 2002-05-23

Family

ID=7896786

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14437400A IL144374A0 (en) 1999-01-29 2000-01-27 Method of identifying cytosine methylation patterns in genomic dna samples

Country Status (10)

Country Link
US (1) US6977146B1 (fr)
EP (1) EP1147228B1 (fr)
JP (1) JP2002535011A (fr)
AT (1) ATE252159T1 (fr)
AU (1) AU764683B2 (fr)
CA (1) CA2359182A1 (fr)
DE (3) DE19905082C1 (fr)
ES (1) ES2208285T3 (fr)
IL (1) IL144374A0 (fr)
WO (1) WO2000044934A2 (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10032529A1 (de) * 2000-06-30 2002-02-07 Epigenomics Ag Diagnose von bedeutenden genetischen Parametern innerhalb des Major Histocompatibility Complex (MHC)
WO2001077377A2 (fr) * 2000-04-06 2001-10-18 Epigenomics Ag Diagnostic de maladies associees a la replication de l'adn
AU2001276371A1 (en) * 2000-06-30 2002-01-14 Epigenomics Ag Method and nucleic acids for analysing the methylation of genes implicated pharmacogenomics
AU2001281311A1 (en) * 2000-07-10 2002-01-21 Epigenx Pharmaceutical, Inc. Detecting methylated cytosine in polynucleotides
DE10037769A1 (de) * 2000-08-03 2002-02-21 Epigenomics Gmbh Diagnose von mit CD24 assoziierten Krankheiten
DK1423528T3 (da) * 2000-09-01 2008-05-13 Epigenomics Ag Fremgangsmåde til bestemmelse af methyleringsgraden af bestemte cytosiner i genomisk DNA i sekvenskonteksten 5-CPG-3
DE10050942B4 (de) * 2000-10-10 2005-11-17 Epigenomics Ag Verfahren zum Nachweis von Cytosin-Methylierungen
AU2002221800A1 (en) * 2000-11-02 2002-05-15 Epigenomics Ag Systems, methods and computer program products for guiding the selection of therapeutic treatment regimens
DE10054972A1 (de) * 2000-11-06 2002-06-06 Epigenomics Ag Diagnose von mit humos assoziierten Krankheiten
DE10054974A1 (de) * 2000-11-06 2002-06-06 Epigenomics Ag Diagnose von mit Cdk4 assoziierten Krankheiten
AUPR142500A0 (en) * 2000-11-13 2000-12-07 Human Genetic Signatures Pty Ltd A peptide nucleic acid-based assay for the detection of specific nucleic acid sequences
DE10056802B4 (de) * 2000-11-14 2005-06-16 Epigenomics Ag Verfahren zur Detektion von Methylierungszuständen zur toxikologischen Diagnostik
DE10061338A1 (de) * 2000-12-06 2002-06-20 Epigenomics Ag Diagnose von mit Angiogenese assoziierten Krankheiten
DE10061348C2 (de) * 2000-12-06 2002-10-24 Epigenomics Ag Verfahren zur Quantifizierung von Cytosin-Methylierungen in komplex amplifizierter genomischer DNA
US20020137086A1 (en) * 2001-03-01 2002-09-26 Alexander Olek Method for the development of gene panels for diagnostic and therapeutic purposes based on the expression and methylation status of the genes
WO2002077895A2 (fr) * 2001-03-26 2002-10-03 Epigenomics Ag Procede de selection d'aspects epigenetiques
DE10128509A1 (de) * 2001-06-14 2003-01-02 Epigenomics Ag Verfahren und Nukleinsäuren für die Differenzierung von Prostata- und Nierenkarzinomen
DE10128508A1 (de) * 2001-06-14 2003-02-06 Epigenomics Ag Verfahren und Nukleinsäuren für die Differenzierung von Prostata-Tumoren
DE10139283A1 (de) * 2001-08-09 2003-03-13 Epigenomics Ag Verfahren und Nukleinsäuren zur Analyse von Colon-Krebs
DE10154317B4 (de) * 2001-10-26 2005-06-09 Epigenomics Ag Verfahren zum Nachweis von Cytosin-Methylierungen in immobilisierten DNA Proben
EP1344832A1 (fr) * 2002-03-15 2003-09-17 Epigenomics AG Procédé et acides nucléiques pour l'analyse de méthylation dans le gène de melastatin
US20050164193A1 (en) * 2002-03-25 2005-07-28 Epigenomics Ag Method for the analysis of methylation patterns within nucleic acids by means of mass spectrometry
US6916621B2 (en) 2002-03-27 2005-07-12 Spectral Genomics, Inc. Methods for array-based comparitive binding assays
WO2004111266A1 (fr) 2003-06-17 2004-12-23 Human Genetic Signatures Pty Ltd Procedes d'amplification de genome
EP1668148B1 (fr) 2003-09-04 2008-12-31 Human Genetic Signatures PTY Ltd. Dosage de detection d'acide nucleique
US8168777B2 (en) 2004-04-29 2012-05-01 Human Genetic Signatures Pty. Ltd. Bisulphite reagent treatment of nucleic acid
JP4980219B2 (ja) 2004-09-10 2012-07-18 ヒューマン ジェネティック シグネチャーズ ピーティーワイ リミテッド インターカレート型擬似ヌクレオチド（ｉｐｎ）を含有するインターカレーティング核酸（ｉｎａ）を含む増幅ブロッカー
NZ555620A (en) 2004-12-03 2008-08-29 Human Genetic Signatures Pty Methods for simplifying microbial nucleic acids by chemical modification of cytosines
WO2006084340A1 (fr) * 2005-02-14 2006-08-17 Commonwealth Scientific And Industrial Research Organisation Dosage en phase solide pour analyse de méthylation
EP1883707B1 (fr) 2005-05-26 2014-04-09 Human Genetic Signatures PTY Ltd Amplification par deplacement de brin isotherme utilisant des amorces contenant une base non reguliere
CN101292046B (zh) 2005-09-14 2013-03-13 人类遗传标记控股有限公司 健康状态的测定法
WO2008135512A2 (fr) * 2007-05-02 2008-11-13 Jerzy Paszkowski Procédé d'amplification de l'adn
AU2008329549B2 (en) 2007-11-27 2013-08-22 Human Genetic Signatures Pty Ltd Enzymes for amplification and copying bisulphite modified nucleic acids
WO2010083046A2 (fr) * 2009-01-15 2010-07-22 The Salk Institute For Biological Studies Procédés ayant recours à un séquençage de nouvelle génération pour identifier les 5-méthylcytosines dans le génome
KR101912488B1 (ko) 2011-09-07 2018-10-26 휴먼 제네틱 시그너처스 피티와이 엘티디 분자 검출 분석법
EP2844768B1 (fr) 2012-04-30 2019-03-13 Raindance Technologies, Inc. Analyse d'analyte numérique
EP2986762B1 (fr) 2013-04-19 2019-11-06 Bio-Rad Laboratories, Inc. Analyse d'analyte numérique

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605798A (en) * 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
CA2153387A1 (fr) * 1993-01-07 1994-07-21 Hubert Koester Sequencage de l'adn par spectrometrie de masse
DE19543065C2 (de) * 1995-11-09 2002-10-31 Gag Bioscience Gmbh Zentrum Fu Verfahren zur Genomanalyse und Mittel zur Durchführung des Verfahrens
WO1997037041A2 (fr) * 1996-03-18 1997-10-09 Sequenom, Inc. Sequençage d'adn par spectrometrie de masse
US5786146A (en) 1996-06-03 1998-07-28 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US6017704A (en) * 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids

Also Published As

Publication number Publication date
JP2002535011A (ja) 2002-10-22
CA2359182A1 (fr) 2000-08-03
EP1147228A2 (fr) 2001-10-24
WO2000044934A3 (fr) 2000-11-30
EP1147228B1 (fr) 2003-10-15
AU3144700A (en) 2000-08-18
AU764683B2 (en) 2003-08-28
WO2000044934A2 (fr) 2000-08-03
DE19905082C1 (de) 2000-05-18
ATE252159T1 (de) 2003-11-15
ES2208285T3 (es) 2004-06-16
DE50004066D1 (de) 2003-11-20
US6977146B1 (en) 2005-12-20
DE10080169D2 (de) 2002-01-24

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