IL144702A0 - Crystal modification c of 8-cyano-1-cyclopropyl-7- (1s, 6s-2, 8 diazabicyclo-[4.3.0.] nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid - Google Patents

Crystal modification c of 8-cyano-1-cyclopropyl-7- (1s, 6s-2, 8 diazabicyclo-[4.3.0.] nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid

Info

Publication number
IL144702A0
IL144702A0 IL14470200A IL14470200A IL144702A0 IL 144702 A0 IL144702 A0 IL 144702A0 IL 14470200 A IL14470200 A IL 14470200A IL 14470200 A IL14470200 A IL 14470200A IL 144702 A0 IL144702 A0 IL 144702A0
Authority
IL
Israel
Prior art keywords
nonan
diazabicyclo
cyclopropyl
dihydro
oxo
Prior art date
Application number
IL14470200A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL144702A0 publication Critical patent/IL144702A0/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL14470200A 1999-02-26 2000-02-14 Crystal modification c of 8-cyano-1-cyclopropyl-7- (1s, 6s-2, 8 diazabicyclo-[4.3.0.] nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid IL144702A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19908449A DE19908449A1 (de) 1999-02-26 1999-02-26 Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
PCT/EP2000/001202 WO2000052009A1 (fr) 1999-02-26 2000-02-14 Modification cristalline c de l'acide 8-cyano -1- cyclopropyl -7-(1s, 6s-2,8- diazabicyclo -[4.3.0] nonan -8-yl) -6-fluoro -1,4- dihydro -4-oxo -3-quinoleine -carboxylique

Publications (1)

Publication Number Publication Date
IL144702A0 true IL144702A0 (en) 2002-06-30

Family

ID=7899027

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14470200A IL144702A0 (en) 1999-02-26 2000-02-14 Crystal modification c of 8-cyano-1-cyclopropyl-7- (1s, 6s-2, 8 diazabicyclo-[4.3.0.] nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid
IL144702A IL144702A (en) 1999-02-26 2001-08-02 C-crystalline change of 8 - cyano - and cyclopropyl - 7 - (8, 2 - S1, S6 - diazabicyclo - [4.3.0] nonan - 8 - il) - 6 - fluoro - 1,4 - dihydro-4 - oxo Quinoline Carboxylic Acid

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL144702A IL144702A (en) 1999-02-26 2001-08-02 C-crystalline change of 8 - cyano - and cyclopropyl - 7 - (8, 2 - S1, S6 - diazabicyclo - [4.3.0] nonan - 8 - il) - 6 - fluoro - 1,4 - dihydro-4 - oxo Quinoline Carboxylic Acid

Country Status (26)

Country Link
US (1) US6649762B1 (fr)
EP (1) EP1155018B1 (fr)
JP (1) JP2002538158A (fr)
KR (1) KR100756471B1 (fr)
CN (1) CN1191253C (fr)
AT (1) ATE226952T1 (fr)
AU (1) AU763003B2 (fr)
BR (1) BR0008493A (fr)
CA (1) CA2362801A1 (fr)
CZ (1) CZ299700B6 (fr)
DE (2) DE19908449A1 (fr)
DK (1) DK1155018T3 (fr)
ES (1) ES2181644T3 (fr)
HK (1) HK1044948B (fr)
HU (1) HUP0200006A3 (fr)
IL (2) IL144702A0 (fr)
NO (1) NO320191B1 (fr)
NZ (1) NZ513750A (fr)
PL (1) PL349368A1 (fr)
PT (1) PT1155018E (fr)
RU (1) RU2248356C2 (fr)
SK (1) SK285562B6 (fr)
TR (1) TR200102434T2 (fr)
UA (1) UA70356C2 (fr)
WO (1) WO2000052009A1 (fr)
ZA (1) ZA200106289B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908448A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
DE19908449A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102006049520A1 (de) * 2006-10-20 2008-04-24 Bayer Healthcare Ag Verfahren zur Herstellung von Pradofloxacin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2676521B2 (ja) 1988-03-22 1997-11-17 北陸製薬株式会社 キノロンカルボン酸化合物ｉ型結晶の製造法
CA2201735A1 (fr) 1994-11-18 1996-05-30 The Upjohn Company Nouvelle forme physiquement stable d'une fluoroquinolone
DE19546249A1 (de) 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
EP0882049B1 (fr) * 1996-02-23 2002-11-20 Bayer Ag Acides 8-cyano-1-cyclopropyl-7-(2,8-diazabicyclo-(4.3.0)-nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinocarboxyliques eventuellement substitues et leurs derives
DE19633805A1 (de) * 1996-02-23 1997-08-28 Bayer Ag Gegenenenfalls substituierte 8-Cyan-l-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre Derivate
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908448A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
DE19908449A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure

Also Published As

Publication number Publication date
AU763003B2 (en) 2003-07-10
DE19908449A1 (de) 2000-08-31
NO20014061L (no) 2001-08-21
UA70356C2 (uk) 2004-10-15
CN1342160A (zh) 2002-03-27
HK1044948B (zh) 2005-10-14
PT1155018E (pt) 2003-02-28
TR200102434T2 (tr) 2002-03-21
EP1155018B1 (fr) 2002-10-30
HUP0200006A2 (en) 2002-06-29
SK11952001A3 (sk) 2001-12-03
IL144702A (en) 2006-07-05
NO20014061D0 (no) 2001-08-21
EP1155018A1 (fr) 2001-11-21
BR0008493A (pt) 2002-02-05
ZA200106289B (en) 2002-07-31
US6649762B1 (en) 2003-11-18
SK285562B6 (sk) 2007-03-01
ATE226952T1 (de) 2002-11-15
KR100756471B1 (ko) 2007-09-07
JP2002538158A (ja) 2002-11-12
CA2362801A1 (fr) 2000-09-08
CN1191253C (zh) 2005-03-02
WO2000052009A1 (fr) 2000-09-08
NZ513750A (en) 2001-09-28
HK1044948A1 (en) 2002-11-08
AU3154300A (en) 2000-09-21
DK1155018T3 (da) 2003-02-17
DE50000700D1 (de) 2002-12-05
CZ20013064A3 (cs) 2002-01-16
KR20010089630A (ko) 2001-10-06
PL349368A1 (en) 2002-07-15
ES2181644T3 (es) 2003-03-01
CZ299700B6 (cs) 2008-10-22
RU2248356C2 (ru) 2005-03-20
NO320191B1 (no) 2005-11-07
HUP0200006A3 (en) 2002-08-28

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