IL148678A0 - Dna sequencing method - Google Patents
Dna sequencing methodInfo
- Publication number
- IL148678A0 IL148678A0 IL14867800A IL14867800A IL148678A0 IL 148678 A0 IL148678 A0 IL 148678A0 IL 14867800 A IL14867800 A IL 14867800A IL 14867800 A IL14867800 A IL 14867800A IL 148678 A0 IL148678 A0 IL 148678A0
- Authority
- IL
- Israel
- Prior art keywords
- dna sequencing
- sequencing method
- polynucleotide
- enzyme
- detection
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 238000001712 DNA sequencing Methods 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9923644.0A GB9923644D0 (en) | 1999-10-06 | 1999-10-06 | DNA sequencing |
| PCT/GB2000/003860 WO2001025480A2 (fr) | 1999-10-06 | 2000-10-06 | Procede de sequençage de l'adn |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL148678A0 true IL148678A0 (en) | 2002-09-12 |
Family
ID=10862234
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14867800A IL148678A0 (en) | 1999-10-06 | 2000-10-06 | Dna sequencing method |
| IL148678A IL148678A (en) | 1999-10-06 | 2002-03-13 | A method for sequencing DNA sequences |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL148678A IL148678A (en) | 1999-10-06 | 2002-03-13 | A method for sequencing DNA sequences |
Country Status (20)
| Country | Link |
|---|---|
| US (4) | US20050214849A1 (fr) |
| EP (1) | EP1226271B1 (fr) |
| JP (2) | JP5030249B2 (fr) |
| KR (1) | KR100809171B1 (fr) |
| CN (1) | CN1159457C (fr) |
| AT (1) | ATE388242T1 (fr) |
| AU (1) | AU769102B2 (fr) |
| BR (1) | BR0014468A (fr) |
| CA (1) | CA2386115C (fr) |
| DE (1) | DE60038244T2 (fr) |
| DK (1) | DK1226271T3 (fr) |
| EA (1) | EA006702B1 (fr) |
| ES (1) | ES2302497T3 (fr) |
| GB (1) | GB9923644D0 (fr) |
| IL (2) | IL148678A0 (fr) |
| IS (1) | IS6333A (fr) |
| MX (1) | MXPA02003534A (fr) |
| NZ (1) | NZ517775A (fr) |
| PT (1) | PT1226271E (fr) |
| WO (1) | WO2001025480A2 (fr) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001511358A (ja) * | 1997-07-28 | 2001-08-14 | メディカル・バイオシステムズ・リミテッド | 核酸配列の解析 |
| US7875440B2 (en) | 1998-05-01 | 2011-01-25 | Arizona Board Of Regents | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
| US6780591B2 (en) | 1998-05-01 | 2004-08-24 | Arizona Board Of Regents | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
| GB9907812D0 (en) * | 1999-04-06 | 1999-06-02 | Medical Biosystems Ltd | Sequencing |
| US7056661B2 (en) | 1999-05-19 | 2006-06-06 | Cornell Research Foundation, Inc. | Method for sequencing nucleic acid molecules |
| EP1681356B1 (fr) | 1999-05-19 | 2011-10-19 | Cornell Research Foundation, Inc. | Procédé de séquenage d'acides nucléiques |
| US7501245B2 (en) | 1999-06-28 | 2009-03-10 | Helicos Biosciences Corp. | Methods and apparatuses for analyzing polynucleotide sequences |
| US6818395B1 (en) | 1999-06-28 | 2004-11-16 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences |
| US7211390B2 (en) | 1999-09-16 | 2007-05-01 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| US7244559B2 (en) | 1999-09-16 | 2007-07-17 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| GB9923644D0 (en) | 1999-10-06 | 1999-12-08 | Medical Biosystems Ltd | DNA sequencing |
| ATE377093T1 (de) | 2000-07-07 | 2007-11-15 | Visigen Biotechnologies Inc | Sequenzbestimmung in echtzeit |
| AU2002227156A1 (en) | 2000-12-01 | 2002-06-11 | Visigen Biotechnologies, Inc. | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity |
| JP2004523243A (ja) | 2001-03-12 | 2004-08-05 | カリフォルニア インスティチュート オブ テクノロジー | 非同期性塩基伸長によってポリヌクレオチド配列を分析するための方法および装置 |
| GB0112238D0 (en) * | 2001-05-18 | 2001-07-11 | Medical Biosystems Ltd | Sequencing method |
| US6902921B2 (en) | 2001-10-30 | 2005-06-07 | 454 Corporation | Sulfurylase-luciferase fusion proteins and thermostable sulfurylase |
| US6956114B2 (en) | 2001-10-30 | 2005-10-18 | '454 Corporation | Sulfurylase-luciferase fusion proteins and thermostable sulfurylase |
| SE0201655D0 (sv) * | 2002-05-31 | 2002-05-31 | Amersham Biosciences Ab | A method of electrophoresis |
| US7575865B2 (en) | 2003-01-29 | 2009-08-18 | 454 Life Sciences Corporation | Methods of amplifying and sequencing nucleic acids |
| CA2513899C (fr) | 2003-01-29 | 2013-03-26 | 454 Corporation | Procede d'amplification et de sequencage d'acides nucleiques |
| CA2532220A1 (fr) * | 2003-07-15 | 2005-01-27 | Daniel Henry Densham | Mesure d'une reaction d'amplification de polynucleotide |
| GB0317343D0 (en) * | 2003-07-24 | 2003-08-27 | Medical Biosystems Ltd | Polynucleotide sequencing |
| US7169560B2 (en) | 2003-11-12 | 2007-01-30 | Helicos Biosciences Corporation | Short cycle methods for sequencing polynucleotides |
| WO2005080605A2 (fr) | 2004-02-19 | 2005-09-01 | Helicos Biosciences Corporation | Procedes et kits pour analyser des sequences de polynucleotides |
| US7635562B2 (en) | 2004-05-25 | 2009-12-22 | Helicos Biosciences Corporation | Methods and devices for nucleic acid sequence determination |
| US7476734B2 (en) | 2005-12-06 | 2009-01-13 | Helicos Biosciences Corporation | Nucleotide analogs |
| US7170050B2 (en) | 2004-09-17 | 2007-01-30 | Pacific Biosciences Of California, Inc. | Apparatus and methods for optical analysis of molecules |
| CA2579150C (fr) | 2004-09-17 | 2014-11-25 | Pacific Biosciences Of California, Inc. | Appareil et procede d'analyse de molecules |
| US7220549B2 (en) | 2004-12-30 | 2007-05-22 | Helicos Biosciences Corporation | Stabilizing a nucleic acid for nucleic acid sequencing |
| US7482120B2 (en) | 2005-01-28 | 2009-01-27 | Helicos Biosciences Corporation | Methods and compositions for improving fidelity in a nucleic acid synthesis reaction |
| US7666593B2 (en) | 2005-08-26 | 2010-02-23 | Helicos Biosciences Corporation | Single molecule sequencing of captured nucleic acids |
| US7397546B2 (en) | 2006-03-08 | 2008-07-08 | Helicos Biosciences Corporation | Systems and methods for reducing detected intensity non-uniformity in a laser beam |
| CA2648149A1 (fr) * | 2006-03-31 | 2007-11-01 | Solexa, Inc. | Systemes et procedes pour analyse de sequencage par synthese |
| GB0721340D0 (en) * | 2007-10-30 | 2007-12-12 | Isis Innovation | Polymerase-based single-molecule DNA sequencing |
| EP4230747A3 (fr) | 2008-03-28 | 2023-11-15 | Pacific Biosciences Of California, Inc. | Compositions et procédés de séquençage d'acide nucléique |
| US9182406B2 (en) * | 2008-08-04 | 2015-11-10 | Biodesy, Inc. | Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability |
| US20110294116A1 (en) * | 2008-12-11 | 2011-12-01 | The Regents of the Unicersity of California | Methods and systems for direct sequencing of single dna molecules |
| US8911972B2 (en) | 2009-12-16 | 2014-12-16 | Pacific Biosciences Of California, Inc. | Sequencing methods using enzyme conformation |
| WO2011159942A1 (fr) | 2010-06-18 | 2011-12-22 | Illumina, Inc. | Sondes conformationnelles et procédés de séquençage d'acides nucléiques |
| GB2503604B (en) | 2011-03-21 | 2020-04-22 | Biodesy Llc | Classification of kinase inhibitors using second harmonic optical techniques |
| DE102013202721A1 (de) * | 2013-02-20 | 2014-08-21 | Siemens Aktiengesellschaft | Sequenziervorrichtung zum Sequenzieren mindestens eines Nukleinsäureeinzelstrangs und Verfahren zum Sequenzieren mindestens eines Nukleinsäureeinzelstrangs |
| GB201306444D0 (en) * | 2013-04-09 | 2013-05-22 | Base4 Innovation Ltd | Single nucleotide detection method |
| CN113913505A (zh) | 2014-07-15 | 2022-01-11 | 亿明达股份有限公司 | 生物化学激活的电子装置 |
| WO2016106286A1 (fr) | 2014-12-23 | 2016-06-30 | Biodesy, Inc. | Fixation de protéines à des interfaces destinées à être utilisées en détection optique non linéaire |
| US10077470B2 (en) | 2015-07-21 | 2018-09-18 | Omniome, Inc. | Nucleic acid sequencing methods and systems |
| EP3449012B1 (fr) | 2016-04-29 | 2020-12-23 | Omniome, Inc. | Procédé de séquençage faisant appel à la déstabilisation d'un complexe ternaire pour identifier des nucléotides apparentés |
| US10428378B2 (en) | 2016-08-15 | 2019-10-01 | Omniome, Inc. | Sequencing method for rapid identification and processing of cognate nucleotide pairs |
| EP3497236B1 (fr) | 2016-08-15 | 2021-11-03 | Omniome, Inc. | Procédé de séquençage d'acides nucléiques |
| EP3562962B1 (fr) | 2016-12-30 | 2022-01-05 | Omniome, Inc. | Procédé et système utilisant des polymérases pouvant être distinguées pour détecter des complexes ternaires et identifier des nucléotides parents |
| WO2018136487A1 (fr) | 2017-01-20 | 2018-07-26 | Omniome, Inc. | Procédé de détection de nucléotides apparentés dans un flux de travaux de séquençage d'acides nucléiques |
| US10161003B2 (en) | 2017-04-25 | 2018-12-25 | Omniome, Inc. | Methods and apparatus that increase sequencing-by-binding efficiency |
| US9951385B1 (en) | 2017-04-25 | 2018-04-24 | Omniome, Inc. | Methods and apparatus that increase sequencing-by-binding efficiency |
| WO2019055867A1 (fr) * | 2017-09-15 | 2019-03-21 | Illumina, Inc. | Système de détection de séquence |
| EP3697932A1 (fr) | 2017-10-19 | 2020-08-26 | Omniome, Inc. | Réduction du bruit de fond et stabilisation de complexes simultanées dans des flux de travaux de dosage par liaison |
| US11499962B2 (en) | 2017-11-17 | 2022-11-15 | Ultima Genomics, Inc. | Methods and systems for analyte detection and analysis |
| US10344328B2 (en) | 2017-11-17 | 2019-07-09 | Ultima Genomics, Inc. | Methods for biological sample processing and analysis |
| US12239980B2 (en) | 2018-12-07 | 2025-03-04 | Ultima Genomics, Inc. | Implementing barriers for controlled environments during sample processing and detection |
| US10512911B1 (en) * | 2018-12-07 | 2019-12-24 | Ultima Genomics, Inc. | Implementing barriers for controlled environments during sample processing and detection |
| US10900078B2 (en) | 2019-03-14 | 2021-01-26 | Ultima Genomics, Inc. | Methods, devices, and systems for analyte detection and analysis |
| US11118223B2 (en) | 2019-03-14 | 2021-09-14 | Ultima Genomics, Inc. | Methods, devices, and systems for analyte detection and analysis |
| US12060148B2 (en) | 2022-08-16 | 2024-08-13 | Honeywell International Inc. | Ground resonance detection and warning system and method |
| CN116287109A (zh) * | 2022-09-29 | 2023-06-23 | 清华大学 | 一种测量单分子rna力谱的方法及其应用 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE462454B (sv) | 1988-11-10 | 1990-06-25 | Pharmacia Ab | Maetyta foer anvaendning i biosensorer |
| GB8910880D0 (en) * | 1989-05-11 | 1989-06-28 | Amersham Int Plc | Sequencing method |
| WO1991006678A1 (fr) | 1989-10-26 | 1991-05-16 | Sri International | Sequençage d'adn |
| US5583026A (en) * | 1994-08-31 | 1996-12-10 | Cornell Research Foundation, Inc. | Process for reconstituting the polymerase III* and other subassemblies of E. coli DNA polymerase III holoenzyme from peptide subunits |
| GB9208733D0 (en) | 1992-04-22 | 1992-06-10 | Medical Res Council | Dna sequencing method |
| US5360714A (en) * | 1992-08-28 | 1994-11-01 | Fox Chase Cancer Center | Hepadnavirus polymerase gene product having RNA-dependent DNA priming and reverse transcriptase activities and methods of measuring the activities thereof |
| CA2158642A1 (fr) | 1993-03-19 | 1994-09-29 | Hubert Koster | Sequencage de l'adn par spectrometrie de masse, via la degradation de l'exonuclease |
| WO1995006138A1 (fr) * | 1993-08-25 | 1995-03-02 | The Regents Of The University Of California | Procede microscopique pour la detection de micro-mouvements |
| US5747247A (en) * | 1994-07-25 | 1998-05-05 | The Regents Of The University Of California | Spectroscopic helicase assay |
| US5801042A (en) * | 1994-08-18 | 1998-09-01 | The Trustees Of Columbia University In The City Of New York | Unique associated Kaposi's sarcoma virus sequences and uses thereof |
| US5753439A (en) * | 1995-05-19 | 1998-05-19 | Trustees Of Boston University | Nucleic acid detection methods |
| WO1998035012A2 (fr) * | 1997-02-12 | 1998-08-13 | Chan Eugene Y | Procedes et produits permettant d'analyser des polymeres |
| CA2282418A1 (fr) * | 1997-03-05 | 1998-09-11 | Scriptgen Pharmaceuticals, Inc. | Selection par anisotropie a fluorescence pour identifier des composes presentant une affinite avec des acides nucleiques |
| US6159687A (en) * | 1997-03-18 | 2000-12-12 | Novo Nordisk A/S | Methods for generating recombined polynucleotides |
| JP2001511358A (ja) | 1997-07-28 | 2001-08-14 | メディカル・バイオシステムズ・リミテッド | 核酸配列の解析 |
| US7875440B2 (en) * | 1998-05-01 | 2011-01-25 | Arizona Board Of Regents | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
| US6263286B1 (en) * | 1998-08-13 | 2001-07-17 | U.S. Genomics, Inc. | Methods of analyzing polymers using a spatial network of fluorophores and fluorescence resonance energy transfer |
| US6210896B1 (en) * | 1998-08-13 | 2001-04-03 | Us Genomics | Molecular motors |
| WO2000009757A1 (fr) | 1998-08-13 | 2000-02-24 | U.S. Genomics, Inc. | Polymeres caracterises optiquement |
| WO2000053805A1 (fr) * | 1999-03-10 | 2000-09-14 | Asm Scientific, Inc. | Procede de sequençage direct d'acides nucleiques |
| GB9907812D0 (en) * | 1999-04-06 | 1999-06-02 | Medical Biosystems Ltd | Sequencing |
| US7056661B2 (en) * | 1999-05-19 | 2006-06-06 | Cornell Research Foundation, Inc. | Method for sequencing nucleic acid molecules |
| US6335420B1 (en) | 1999-11-22 | 2002-01-01 | Ibc Advanced Technologies, Inc. | Polyamide ligand-containing polymeric resins and methods of using the same for removing, separating and/or concentrating desired metal ions from solutions |
| GB9923644D0 (en) * | 1999-10-06 | 1999-12-08 | Medical Biosystems Ltd | DNA sequencing |
| US6908736B1 (en) * | 1999-10-06 | 2005-06-21 | Medical Biosystems, Ltd. | DNA sequencing method |
| GB0112238D0 (en) | 2001-05-18 | 2001-07-11 | Medical Biosystems Ltd | Sequencing method |
| GB0317343D0 (en) | 2003-07-24 | 2003-08-27 | Medical Biosystems Ltd | Polynucleotide sequencing |
| GB0413082D0 (en) | 2004-06-11 | 2004-07-14 | Medical Biosystems Ltd | Method |
| US8262900B2 (en) * | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| US20100301398A1 (en) * | 2009-05-29 | 2010-12-02 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
| US20100137143A1 (en) * | 2008-10-22 | 2010-06-03 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
| US8574835B2 (en) * | 2009-05-29 | 2013-11-05 | Life Technologies Corporation | Scaffolded nucleic acid polymer particles and methods of making and using |
| US8673627B2 (en) * | 2009-05-29 | 2014-03-18 | Life Technologies Corporation | Apparatus and methods for performing electrochemical reactions |
-
1999
- 1999-10-06 GB GBGB9923644.0A patent/GB9923644D0/en not_active Ceased
-
2000
- 2000-10-06 AT AT00964544T patent/ATE388242T1/de not_active IP Right Cessation
- 2000-10-06 EP EP00964544A patent/EP1226271B1/fr not_active Expired - Lifetime
- 2000-10-06 ES ES00964544T patent/ES2302497T3/es not_active Expired - Lifetime
- 2000-10-06 NZ NZ517775A patent/NZ517775A/en unknown
- 2000-10-06 CA CA2386115A patent/CA2386115C/fr not_active Expired - Lifetime
- 2000-10-06 EA EA200200428A patent/EA006702B1/ru not_active IP Right Cessation
- 2000-10-06 WO PCT/GB2000/003860 patent/WO2001025480A2/fr not_active Ceased
- 2000-10-06 JP JP2001528630A patent/JP5030249B2/ja not_active Expired - Fee Related
- 2000-10-06 AU AU75467/00A patent/AU769102B2/en not_active Expired
- 2000-10-06 BR BR0014468-1A patent/BR0014468A/pt not_active Application Discontinuation
- 2000-10-06 KR KR1020027004272A patent/KR100809171B1/ko not_active Expired - Fee Related
- 2000-10-06 PT PT00964544T patent/PT1226271E/pt unknown
- 2000-10-06 DK DK00964544T patent/DK1226271T3/da active
- 2000-10-06 CN CNB008137854A patent/CN1159457C/zh not_active Expired - Lifetime
- 2000-10-06 IL IL14867800A patent/IL148678A0/xx unknown
- 2000-10-06 DE DE60038244T patent/DE60038244T2/de not_active Expired - Lifetime
- 2000-10-06 MX MXPA02003534A patent/MXPA02003534A/es unknown
-
2002
- 2002-03-13 IL IL148678A patent/IL148678A/en not_active IP Right Cessation
- 2002-04-05 IS IS6333A patent/IS6333A/is unknown
-
2005
- 2005-05-11 US US11/126,481 patent/US20050214849A1/en not_active Abandoned
-
2010
- 2010-02-22 US US12/710,059 patent/US7939264B1/en not_active Expired - Fee Related
-
2011
- 2011-03-29 US US13/074,949 patent/US20110177520A1/en not_active Abandoned
- 2011-12-01 JP JP2011264043A patent/JP2012196201A/ja active Pending
-
2012
- 2012-05-04 US US13/464,285 patent/US20120214164A1/en not_active Abandoned
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