IL149364A0 - Hydroxamic acid derivative as inhibitor of the formation of soluble human cd23 - Google Patents

Hydroxamic acid derivative as inhibitor of the formation of soluble human cd23

Info

Publication number: IL149364A0
Authority: IL; Israel
Prior art keywords: inhibitor; formation; acid derivative; hydroxamic acid; soluble human
Prior art date: 1999-10-27

Application number

IL14936400A

Other languages

English (en)

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-27

Filing date

2000-10-25

Publication date

2002-11-10

2000-10-25 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2002-11-10 Publication of IL149364A0 publication Critical patent/IL149364A0/xx

Links

NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 title 1
239000002253 acid Substances 0.000 title 1
230000015572 biosynthetic process Effects 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)

IL14936400A 1999-10-27 2000-10-25 Hydroxamic acid derivative as inhibitor of the formation of soluble human cd23 IL149364A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9925470.8A GB9925470D0 (en)	1999-10-27	1999-10-27	Novel compounds
PCT/EP2000/010649 WO2001030747A1 (en)	1999-10-27	2000-10-25	Hydroxamic acid derivative as inhibitor of the formation of soluble human cd23

Publications (1)

Publication Number	Publication Date
IL149364A0 true IL149364A0 (en)	2002-11-10

Family

ID=10863507

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL14936400A IL149364A0 (en)	1999-10-27	2000-10-25	Hydroxamic acid derivative as inhibitor of the formation of soluble human cd23

Country Status (31)

Country	Link
US (2)	US6673965B1 (cs)
EP (1)	EP1224164B1 (cs)
JP (1)	JP3922431B2 (cs)
KR (1)	KR20020044578A (cs)
CN (1)	CN1182107C (cs)
AR (1)	AR026244A1 (cs)
AT (1)	ATE284382T1 (cs)
AU (1)	AU766072B2 (cs)
BR (1)	BR0015082A (cs)
CA (1)	CA2389319A1 (cs)
CO (1)	CO5261576A1 (cs)
CZ (1)	CZ20021424A3 (cs)
DE (1)	DE60016622T2 (cs)
DK (1)	DK1224164T3 (cs)
ES (1)	ES2233474T3 (cs)
GB (1)	GB9925470D0 (cs)
GC (1)	GC0000142A (cs)
HU (1)	HUP0203270A3 (cs)
IL (1)	IL149364A0 (cs)
MX (1)	MXPA02004228A (cs)
MY (1)	MY133601A (cs)
NO (1)	NO20021965L (cs)
NZ (1)	NZ518566A (cs)
PE (1)	PE20010898A1 (cs)
PL (1)	PL356524A1 (cs)
PT (1)	PT1224164E (cs)
SI (1)	SI1224164T1 (cs)
TW (1)	TW561141B (cs)
UY (1)	UY26416A1 (cs)
WO (1)	WO2001030747A1 (cs)
ZA (1)	ZA200203255B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5524215B2 (ja) *	2008-09-19	2014-06-18	ファイザー・インク	抗菌剤として有用なヒドロキサム酸誘導体
EP2507266B1 (en)	2009-12-01	2015-02-18	Boston Medical Center Corporation	TREATMENT OF IgE-MEDIATED DISEASE
WO2011073845A1 (en)	2009-12-16	2011-06-23	Pfizer Inc.	N-linked hydroxamic acid derivatives useful as antibacterial agents
ES2626457T3 (es)	2011-03-07	2017-07-25	Pfizer Inc.	Derivados de fluoro-piridinona útiles como agentes antibacterianos
ES2526687T3 (es)	2011-04-08	2015-01-14	Pfizer Inc.	Derivados de isoxazol útiles como agentes antibacterianos
CA2830866A1 (en)	2011-04-08	2012-10-11	Pfizer Inc.	Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents
EP2525213A1 (en) *	2011-05-16	2012-11-21	Renishaw plc	Spectroscopic apparatus and methods for determining components present in a sample

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9513331D0 (en)	1995-06-30	1995-09-06	British Biotech Pharm	Matrix metalloproteinase inhibitors
GB9813451D0 (en) *	1998-06-22	1998-08-19	Smithkline Beecham Plc	Novel compounds

1999
- 1999-10-27 GB GBGB9925470.8A patent/GB9925470D0/en not_active Ceased
2000
- 2000-10-25 DK DK00975954T patent/DK1224164T3/da active
- 2000-10-25 AR ARP000105622A patent/AR026244A1/es not_active Application Discontinuation
- 2000-10-25 AT AT00975954T patent/ATE284382T1/de not_active IP Right Cessation
- 2000-10-25 MX MXPA02004228A patent/MXPA02004228A/es active IP Right Grant
- 2000-10-25 ES ES00975954T patent/ES2233474T3/es not_active Expired - Lifetime
- 2000-10-25 CN CNB008173680A patent/CN1182107C/zh not_active Expired - Fee Related
- 2000-10-25 GC GCP2000972 patent/GC0000142A/xx active
- 2000-10-25 JP JP2001533102A patent/JP3922431B2/ja not_active Expired - Fee Related
- 2000-10-25 BR BR0015082-7A patent/BR0015082A/pt not_active IP Right Cessation
- 2000-10-25 DE DE60016622T patent/DE60016622T2/de not_active Expired - Lifetime
- 2000-10-25 NZ NZ518566A patent/NZ518566A/en unknown
- 2000-10-25 AU AU13895/01A patent/AU766072B2/en not_active Ceased
- 2000-10-25 PL PL00356524A patent/PL356524A1/xx unknown
- 2000-10-25 KR KR1020027005340A patent/KR20020044578A/ko not_active Withdrawn
- 2000-10-25 UY UY26416A patent/UY26416A1/es not_active Application Discontinuation
- 2000-10-25 PT PT00975954T patent/PT1224164E/pt unknown
- 2000-10-25 WO PCT/EP2000/010649 patent/WO2001030747A1/en not_active Ceased
- 2000-10-25 SI SI200030603T patent/SI1224164T1/xx unknown
- 2000-10-25 HU HU0203270A patent/HUP0203270A3/hu unknown
- 2000-10-25 MY MYPI20005012A patent/MY133601A/en unknown
- 2000-10-25 EP EP00975954A patent/EP1224164B1/en not_active Expired - Lifetime
- 2000-10-25 CA CA002389319A patent/CA2389319A1/en not_active Abandoned
- 2000-10-25 US US10/111,209 patent/US6673965B1/en not_active Expired - Fee Related
- 2000-10-25 IL IL14936400A patent/IL149364A0/xx unknown
- 2000-10-25 CZ CZ20021424A patent/CZ20021424A3/cs unknown
- 2000-10-26 TW TW089122497A patent/TW561141B/zh active
- 2000-10-26 CO CO00081571A patent/CO5261576A1/es not_active Application Discontinuation
- 2000-10-27 PE PE2000001156A patent/PE20010898A1/es not_active Application Discontinuation
2002
- 2002-04-24 ZA ZA200203255A patent/ZA200203255B/en unknown
- 2002-04-25 NO NO20021965A patent/NO20021965L/no unknown
2003
- 2003-10-03 US US10/678,679 patent/US20040077727A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1224164B1 (en)	2004-12-08
AU1389501A (en)	2001-05-08
HUP0203270A3 (en)	2003-11-28
EP1224164A1 (en)	2002-07-24
HUP0203270A2 (hu)	2003-02-28
MXPA02004228A (es)	2002-10-17
DK1224164T3 (da)	2005-03-29
ES2233474T3 (es)	2005-06-16
CA2389319A1 (en)	2001-05-03
TW561141B (en)	2003-11-11
KR20020044578A (ko)	2002-06-15
MY133601A (en)	2007-11-30
US20040077727A1 (en)	2004-04-22
BR0015082A (pt)	2003-04-15
AU766072B2 (en)	2003-10-09
CN1411436A (zh)	2003-04-16
NO20021965D0 (no)	2002-04-25
CO5261576A1 (es)	2003-03-31
JP3922431B2 (ja)	2007-05-30
AR026244A1 (es)	2003-02-05
SI1224164T1 (en)	2005-06-30
ATE284382T1 (de)	2004-12-15
PL356524A1 (en)	2004-06-28
DE60016622D1 (de)	2005-01-13
JP2003512450A (ja)	2003-04-02
PT1224164E (pt)	2005-04-29
CZ20021424A3 (cs)	2002-09-11
HK1049146A1 (en)	2003-05-02
WO2001030747A1 (en)	2001-05-03
ZA200203255B (en)	2003-03-20
NO20021965L (no)	2002-06-13
US6673965B1 (en)	2004-01-06
PE20010898A1 (es)	2001-10-13
DE60016622T2 (de)	2005-11-03
GC0000142A (en)	2005-06-29
UY26416A1 (es)	2001-05-31
CN1182107C (zh)	2004-12-29
NZ518566A (en)	2004-02-27
GB9925470D0 (en)	1999-12-29

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HUP0200119A2 (en)	2002-06-29	Sulfamato hydroxamic acid metalloprotease inhibitor
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IL149364A0 (en)	2002-11-10	Hydroxamic acid derivative as inhibitor of the formation of soluble human cd23
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